Basic Information

Insect: Thumatha senex
Gene Symbol: -
Assembly: GCA_948477245.1
Location: OX419732.1:21245442-21275464[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3.2e-05 0.0032 18.8 1.4 1 23 418 440 418 440 0.96

2 20 0.0024 0.24 12.9 1.5 1 20 446 465 446 468 0.94

3 20 1.2e-05 0.0012 20.2 5.8 1 23 487 509 487 509 0.98

4 20 2.7e-06 0.00027 22.2 3.7 1 23 515 537 515 537 0.99

5 20 3.9e-05 0.004 18.5 5.3 1 23 543 565 543 565 0.97

6 20 7.7e-07 7.8e-05 23.9 5.2 1 23 571 593 571 593 0.98

7 20 9.7e-07 9.7e-05 23.6 3.1 1 23 599 621 599 621 0.97

8 20 0.00011 0.011 17.1 6.7 1 23 627 649 627 649 0.97

9 20 0.00015 0.015 16.7 6.7 1 23 655 677 655 677 0.97

10 20 5.2e-07 5.2e-05 24.4 1.9 1 23 683 705 683 705 0.98

11 20 1e-05 0.001 20.3 7.7 1 23 711 733 711 733 0.98

12 20 4.4e-05 0.0044 18.4 6.8 1 23 739 761 739 761 0.98

13 20 9.2e-06 0.00092 20.5 5.3 1 23 767 789 767 789 0.98

14 20 3.1e-06 0.00031 22.0 6.1 1 23 795 817 795 817 0.97

15 20 7.3e-07 7.3e-05 24.0 5.0 1 23 823 845 823 845 0.98

16 20 3.3e-06 0.00033 21.9 6.0 1 23 851 873 851 873 0.98

17 20 6e-05 0.006 17.9 7.8 1 23 879 901 879 901 0.97

18 20 2.9e-05 0.0029 18.9 6.4 1 23 907 929 907 929 0.98

19 20 0.0012 0.13 13.8 0.9 1 23 936 958 936 958 0.96

20 20 0.043 4.3 8.9 4.1 1 23 969 991 969 991 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3.2e-05	0.0032	18.8	1.4	1	23	418	440	418	440	0.96
2	20	0.0024	0.24	12.9	1.5	1	20	446	465	446	468	0.94
3	20	1.2e-05	0.0012	20.2	5.8	1	23	487	509	487	509	0.98
4	20	2.7e-06	0.00027	22.2	3.7	1	23	515	537	515	537	0.99
5	20	3.9e-05	0.004	18.5	5.3	1	23	543	565	543	565	0.97
6	20	7.7e-07	7.8e-05	23.9	5.2	1	23	571	593	571	593	0.98
7	20	9.7e-07	9.7e-05	23.6	3.1	1	23	599	621	599	621	0.97
8	20	0.00011	0.011	17.1	6.7	1	23	627	649	627	649	0.97
9	20	0.00015	0.015	16.7	6.7	1	23	655	677	655	677	0.97
10	20	5.2e-07	5.2e-05	24.4	1.9	1	23	683	705	683	705	0.98
11	20	1e-05	0.001	20.3	7.7	1	23	711	733	711	733	0.98
12	20	4.4e-05	0.0044	18.4	6.8	1	23	739	761	739	761	0.98
13	20	9.2e-06	0.00092	20.5	5.3	1	23	767	789	767	789	0.98
14	20	3.1e-06	0.00031	22.0	6.1	1	23	795	817	795	817	0.97
15	20	7.3e-07	7.3e-05	24.0	5.0	1	23	823	845	823	845	0.98
16	20	3.3e-06	0.00033	21.9	6.0	1	23	851	873	851	873	0.98
17	20	6e-05	0.006	17.9	7.8	1	23	879	901	879	901	0.97
18	20	2.9e-05	0.0029	18.9	6.4	1	23	907	929	907	929	0.98
19	20	0.0012	0.13	13.8	0.9	1	23	936	958	936	958	0.96
20	20	0.043	4.3	8.9	4.1	1	23	969	991	969	991	0.99

Sequence Information

Coding Sequence: ATGACAAAAAATGGCATAGTTACTGATTTAACTCGATTGCAGGAACAGAACCAACGAATTCAATCGACCCAACAACAGCAACAAAGCAACTTACCTGCCACGACATCCGCTACTGATCTGCGAGTGAATTCTGTTAACTCTGCTGTGAATGTCGCTTTGTCCAGTGTGGCAAAATATTGGGTGTTTACAAATTTGTTTCCCGGACCTATACCTCAAGTATCTGTTTATGGCCTACCTGCTGGAGCCAGAATTGAAAATGGGAAACCTGTGCAGGATCTCGGACAAGCTCATGCAAGCATACTTAATGGGGACCCAAATATTATTCTTGGACATCATGGTGGACAATCCCAAGTCACTGTGTCAGCTGCAGGTGGCCAGCAGATACCAGTTTCTCAGATTATTGCCACACAGTCTGGCCAAACACATGAAGCACTTGTGGCTCACAGTCAGCAAGCGGAACTTGTGGCGGCTCAGGCTTCCAACAATAATGGGCAGGTGCAAGTTAGCACTGGCCAGCCTACTCATCAGCAGGTACCCAATAACCGGGTCGAATTTGTACAACACCATAATATCGATATGGGGCACCATTCACAACAGCATCTGCTACAACAACAGCTCATGGCTACATCGAGGCCAGACCATAGCAACCAACAGATACAATTGACTGTTAGCGAAGATGGTATCGTGACGGTAATGGAACCAGCAGGCACTAAACTTGTCGATAAGGACGAACTCCACGAAGCCATTAAGATGCCAACTGAACATGGCCTCACAGTTCATCAGCTGCAGCAAATAGTTGGACAACAGGTGATAGACAGCGTGGTTCGCATCGAGCAAGCTACTGGCGAGCCTGCCAACATCCTAGTGACGCACAACGCTGACGGTACGACGTCGATAGAAGCAAGTGCCGCAGAAACACTTATAATCAAGGATGAAAAGAGCTCAAAGATGGAAACGGCACAATTTGCTATACCGGCAGATATTAAGGATATTAAAGGCATAGATTTAAAGAATGTAGGGACAATGGGAATGGAAGGCGCAGTGGTCAAGATATCAGCCGGTACATCCGATCATGATCTTCATGCTATGTACAAAGTCAATGTTGAAGACCTCTCGCAGTTGCTAGCTTATCATGAAGTATTTGGTAAATTAAATACAGAAGGACAGCAACAACCTAAGGTTATAAGTGAAGTGGAAGTAGAAGCGGGTACGAGTGCAGCTATGTCAGAAGCCGAGTCGTCTCCAGGACATCATGCATGTGATATTTGTGGCAAAGTATTCCAATTCCGGTACCAACTTATTGTACACAGGCGTTACCATGGCGAAAGCAAACCGTTCACATGTCATGTTTGTGGGTCCGCCTTTGCAAATCCCGTCGATCTATCGAGGCACGGAAAGTGTCATCTTGCCGGTGACCCCAGTGAGAGACAGGCTAAGAGAATGGCTCAGGATAAGCCATACGTCTGCACAACCTGTCATAAAACATTCTCTCGGAAAGAGCATTTAGACAATCATGTTCGAAGTCATACTGGAGAGACTCCATACAGGTGCGAGTACTGCGCAAAAACGTTTACTCGTAAGGAGCACTTGGTGAACCATGTCCGTAAACACACGGGAGAAACGCCTCATCGCTGCGATATATGCAAGAAAAGCTTCACGCGGAAAGAACACTTTATGAATCATGTCATGTGGCATACAGGTGAAACGCCACACCAATGTCAAATATGCGGCAAGAAGTATACTAGGAAAGAGCATTTAGTGAACCATATGAGATCACACACAAACGATACACCGTTTCGATGCGATCTGTGTGGCAAGACGTTCACGAGAAAGGAACACTTCACCAATCACATATTGTGGCATACGGGTGAAACTCCGCATCGCTGTGATTTCTGCTCGAAGACATTCACGCGTAAGGAGCACTTACTAAACCACGTTCGTCAGCACACTGGGGAATCGCCACATAGATGTACTTTCTGCAGTAAATCGTTTACTCGGCGAGAGCATCTTGTTAATCACGTTAGACAACATACTGGAGAAACTCCTTTCCAATGTGGATACTGTCCAAAGGCGTTCACTAGGAAAGATCATCTAGTGAATCACGTTCGCCAACACACAGGCGAGTCTCCACACAAATGCTCGTATTGCACCAAGTCGTTCACTCGTAAAGAACACCTCACGAATCACGTGCGACAACACACCGGCGAGTCGCCACATCGATGTACATTCTGCGCTAAATCTTTTACTAGAAAAGAACATCTTACTAATCATATCAGACAGCACACGGGAGAAACGCCACACAAGTGCACGTACTGCTCGCGCGCGTTCGCTCGCAAGGAGCACCTCAACAACCACATTCGTCAGCACACCGGCGTCACGCCGCACTCCTGCTCCTACTGCAACAAGAGCTTCACTAGGAAGGAGCATCTCGTCAACCATATACGGCAACACACAGGCGAGACTCCATTTAAATGCACATACTGCTCGAAATCATTCTCTCGTAAGGAACATTTGACGAATCACATAAATCTTCATACAGGGGAGACGCCGCACAAATGTCCATTCTGCACCAAAACATTCTCAAGAAAGGAACATTTGACGAATCATGTCAGAATACACACTGGAGAGTCACCGCATCGGTGTGAGTTCTGTCAGAAGACGTTCACACGGAAGGAGCATCTTACAAATCACTTGAAACAACATACTGGCGTCACGGAGCACACGTGTAAAGTATGCGCTAAACACTTCACTAGAAAAGAACATCTTGTCGCACATATGAGATCACACAGTTGCGGCGAAAAGCCTCACACTTGTGGTGAGTGTGGGAAGTCGTTCCCCTTAAAAGGGAATCTTCTGTTCCATGAGCGCTCCCACAACAAGTCTAACGCAAATGCTAACAAACCCTACCGGTGTGAAGTTTGCGCTAAGGAATTTATGTGTAAAGGACATCTGGTATCGCACAGGCGCACACATTCAGACACGGGTGAAGCCGCACCTTCGGGGACTGAGGCACCACCTGAAGCTGAAGATTGCACTGCCGACTGCAATAAGTGCATCAAAGTGGAACCCGAACGACCTGACATGAAACATGAAATCAGGACGTCTGTAGATACAAGACCACCCGAAAGCAACATTATACAACCACAGCAAAATACTGCTCAAACTGTGATGCAAATCAGCAATCAGCAGATCCGTGTGGGCACATCAAGCGCAGGCGGCGTGGTGGGCAGCGTGAACAGCGCGGCGGGCGTCACCACCGGCACCTTCACGCACACCGTGCCCGCGCCGCACCACCCCGCCGCGCACCACCCCGTGCCCGTCAACTATTAG
Protein Sequence: MTKNGIVTDLTRLQEQNQRIQSTQQQQQSNLPATTSATDLRVNSVNSAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPAGARIENGKPVQDLGQAHASILNGDPNIILGHHGGQSQVTVSAAGGQQIPVSQIIATQSGQTHEALVAHSQQAELVAAQASNNNGQVQVSTGQPTHQQVPNNRVEFVQHHNIDMGHHSQQHLLQQQLMATSRPDHSNQQIQLTVSEDGIVTVMEPAGTKLVDKDELHEAIKMPTEHGLTVHQLQQIVGQQVIDSVVRIEQATGEPANILVTHNADGTTSIEASAAETLIIKDEKSSKMETAQFAIPADIKDIKGIDLKNVGTMGMEGAVVKISAGTSDHDLHAMYKVNVEDLSQLLAYHEVFGKLNTEGQQQPKVISEVEVEAGTSAAMSEAESSPGHHACDICGKVFQFRYQLIVHRRYHGESKPFTCHVCGSAFANPVDLSRHGKCHLAGDPSERQAKRMAQDKPYVCTTCHKTFSRKEHLDNHVRSHTGETPYRCEYCAKTFTRKEHLVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHQCQICGKKYTRKEHLVNHMRSHTNDTPFRCDLCGKTFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCTFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSYCTKSFTRKEHLTNHVRQHTGESPHRCTFCAKSFTRKEHLTNHIRQHTGETPHKCTYCSRAFARKEHLNNHIRQHTGVTPHSCSYCNKSFTRKEHLVNHIRQHTGETPFKCTYCSKSFSRKEHLTNHINLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCEFCQKTFTRKEHLTNHLKQHTGVTEHTCKVCAKHFTRKEHLVAHMRSHSCGEKPHTCGECGKSFPLKGNLLFHERSHNKSNANANKPYRCEVCAKEFMCKGHLVSHRRTHSDTGEAAPSGTEAPPEAEDCTADCNKCIKVEPERPDMKHEIRTSVDTRPPESNIIQPQQNTAQTVMQISNQQIRVGTSSAGGVVGSVNSAAGVTTGTFTHTVPAPHHPAAHHPVPVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00704247;
90% Identity: iTF_01166931;
80% Identity: -