Edil006476.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Euglossa dilemma
Gene Symbol
znf423
Assembly
GCA_002201625.1
Location
NIJG01000047.1:5382486-5400167[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 7.5e-06 0.00056 20.0 1.5 1 23 92 114 92 114 0.98
2 20 0.43 32 5.0 3.9 1 23 120 142 120 142 0.97
3 20 9.3e-07 6.9e-05 22.8 4.3 1 23 148 170 148 170 0.99
4 20 0.0002 0.015 15.5 0.2 1 23 176 198 176 198 0.99
5 20 0.00016 0.012 15.8 0.6 1 23 352 375 352 375 0.96
6 20 0.13 10 6.6 0.0 2 23 386 408 385 408 0.88
7 20 0.18 14 6.2 0.1 3 23 471 491 470 491 0.97
8 20 0.016 1.2 9.5 0.2 1 23 503 525 503 525 0.96
9 20 0.013 0.95 9.8 0.3 1 23 534 557 534 557 0.92
10 20 3.4 2.5e+02 2.2 0.2 1 23 562 585 562 585 0.91
11 20 0.089 6.7 7.2 2.0 2 23 659 680 659 680 0.96
12 20 0.0084 0.63 10.4 0.1 1 23 685 708 685 709 0.94
13 20 1.1 83 3.7 0.1 2 23 773 796 772 796 0.83
14 20 0.00016 0.012 15.8 1.1 2 23 812 834 811 834 0.96
15 20 0.037 2.8 8.3 1.0 1 23 843 866 843 866 0.93
16 20 0.011 0.81 10.0 0.2 2 23 1055 1077 1054 1077 0.96
17 20 0.013 0.99 9.8 0.5 1 23 1087 1110 1087 1110 0.96
18 20 1.1 84 3.7 0.4 2 23 1122 1143 1121 1143 0.94
19 20 0.43 32 5.0 0.1 2 23 1152 1174 1151 1174 0.93
20 20 0.02 1.5 9.2 3.1 1 23 1181 1204 1181 1204 0.97

Sequence Information

Coding Sequence
ATGTTGTTTAAGGGGAACAGTTCAAGGTTGGAGCTGTTGATAGGAAAAATCCAGGCCCATAAAGAACCTACTCAGGAGGAGCAGCATAAGTCCAAAGAGGCCTTGGGGACCGGAAGTTCGTCGTGGCAGAGCGAGGATGGCGGGCCGAACTCGCGACGCGGCGGAGAGACGCCGTCGTCTTGCGCGACGCCGACGTCGGCCAGCTTCCCGTCGGAACCTGAGGTCGACGCCGACGTCGGCGTCAACACTGACGGGAACAACGCCACCGCGCCCTACCCCTGCCAATTCTGCGACCGTACGTTTCCTCGGCTCAGCTACCTGAAGAAGCACGAACAGAGCCACGGTGACCAAATGCCATACAGATGCAGCTGGTGTGCCAGATTATTCAAACATAAACGCAGCAGAGATCGACACGTGAAGCTTCACACAGGAGACCGAAGATATCGATGCACGCACTGCGAGGCTGCTTTCTCCAGGAGTGACCACCTAAAGATCCACATGAAGACACACGACACCCAGAAGCCGTATCAGTGCACGGCCTGTTCCAGAGGTTACAACACAGCAGCTGCTTTAACATCGCACATGCAGTCGCACAAAAAACATCATCAATCGCAAGGAACGACCAAGCTCCAAGAGATCGATTATGGTAGAAGAAGCGTGTCCTCTCACAGTACGTCTTCGCCACCTGTGCCGAGTTCTCCGTCGCCATCTTTAAACCTCGCGTTGAATCCGAAAACTGGCCTGAAGAGCTCCCAGGGTAGCGCTTCGACCACTCCAATTCTGAGCTCTCCGTTGAAGTTGGCCTGTATGTACTGCACCAGAGACTCCTTCAGCTGCATGCAACAGCTGCAGATGCACGTGCACACGATGCACCAGGCTATCCTGAGCGGAGAAACGGTCGCGGTATCTCCGTCGACCAATAGAAGCAACGAGCAAATAGCTTATCAACGCGAAAAGAATTTGGATCGACCAAAGGGTACTTCGAAGGAGCACGAAAAGAAGTATCAAGAGGATGCAGAGGGATCGATCGAGAAGGATCACTATGAAAACGCGTTCACGTGCAGCCAGTGCACCATGAAGTTCTCCACGCTAGGCTCTCTGAGAGATCATCTGATTTCTATTCACAGAACCGACGGTTTCGGATCTACCTTGATGATGTGTCCTCTCTGTGGCATTCCCTGCACTTCTGCTGCAGCTTATGCAGAGCATTACGTTCTCCAACACTGCGAGAATCGACGAGTAGGTCCTCTAGAGGCCAGAGAGTATATAGATTCCAAGATGAACGGAAGTTACGACTGTAAAAGTTCCAGGAGCCAGAAATGCAGGGAGCAAACGTCCTCTGAGCCAGCGGATTTAACCAGTAAGCATTCCACCACTACAGAAAGCAATTATACAGCTGGTACATTGTTGTGTGGTCAGTGTGGCGCAGCATTAAAGGATTTCGAGTCGTTCAGAGAACACTTGGCGAGACATCTGCAAGCCGATCATCGAAACGACGTCGTTAGGCACCCTTGCCCTAAATGCGAGGCTATATTCCAAGACAGAGAAGACATGCTGGTACACTTGACGAAACATTACCTTGGTCAGATCAGCAAAGAGTACGCTTGCGGCGCTTGCAAGAAGCTCTATCCTCATCCTGATCTTCTTCAGAGACACTTGCTCGATAGTCACGCTCACCACCTCTACAGATGCGCTCTATGCAGGGACACTTTCGATTCCAGAGTCGCGATACAAGTCCATTTCGCCGTGAAACATAGTCAGGAGTGCAGGATCTACCGATGCAATGCTTGCACGGTGCCTAATAACGAAAACTCGCCAGGGAACGCGCCGGGGGAGGGAAAAAGTTTCTTTAGAAGCGAATCCGAGATGGCAAACCACGTGAGGAACGTCCACGCACCTCCCACCGTGTCGAGTAACAGTCCTGTTGCCAGAAGTCCTGCTTCTACTCCAGGGATAACTGGAAATTCCGGACCAAGATGCGTCTTCTGCGGGATTTGTTGTAGTTCCGAGCTTGAACTACAGCTTCATTTGGCTAGCCATTCTGCAAACTTGTACAGGTGTCCGGTTTGCAGAGAAGGATTTGCCGTAGAATTCCTGTTGGACAGGCATATTGCTCAAGCACATCATTCTAGCGATCATCAAGGTGCTGTGAGAAGTAGTTCTAGGGAAAACGGAAGGATCGGTAAACCACCAAGATTACAGGAAGAGGCTAAATCTCAGAAAAGAGGCCGCTCTCCAGCATCCAGCAACAATAATTCGCTAAACCAACGGGACAACAACAATAAACGTCCAAATTATACCAATACATCGTCCCAGCAGTGCGATCTCTGTGAAAGGGGAGAGTTCACCAACGAAGCGGAACTTCAAGCCCACAAAAAACTTGCTCACAGTACAGCTAAGCTTCAAAACAAGTCCATATCGAACCTGAGCATGACCTGCGCGTACTGTGGAGAAGTATGTCGTTCTAGAACCGATCTAGAATCTCACACGAGAATTCAACACGCTTCGAACGAACCCGGTGGACGCCACAAGTGCAACATCTGCGACGAGGTTTGCCCCTCGGGTGCAACTCTTGCCGAACACAAACTGCAGAAACATTGTAAGATTCAGTTAAGTGACACGTGCATCGTTTGCCGAGGAAACTTGACTACAGAGTCGCAATTTCTGGAACACGTGCAAAGACACAGTCTGGAGAACGTGGACCCTCAACAAAGATTAGACGGTTCCCTTCCTCATCTTCCTGCGGCATGTGTAGTTTGCAGACAGACGTTGATCAGTGATTTAGAATGTCGTCTTCACGCCAGACATCATTTGAGAGCATCTACTGGTTCTCATAGCGTGGGATCTAGTCCCAGCCCTAATCAGAAGAGCCAAAGTCCAAATTGTTGTCTTTGTTTAAGAGATTATTCGGCCGATGACTTTGTTAATTTACCTCCGAATCATATAAGTGGGGGAGGACAATCCTTAAGGGTCTGCAAGTCTTGCTACATTCGTCATTCTCAGGGTTTACCTATTTTGAATACACCGTATGAACCTCTTAGGTCTAAATGCGATGGTCCTTGGATATCCAGTAATAAAGATGGCCAGTGGGATGGATCGAGGGATAGACGGGAGCCAGAGAGTAGATTTAAAGAAGATAGAAACGAGGTAAATGATAATAAAAGATGTCAGGACTGTGGTGTAAAGTTTGAAGGTTCCGAGGAGGCGGAGAAACATAGGATGATGGAACATGAAAAGGCTGCGACTGCTTCAAACACGTATACGTGTATACAGTGTCAGACGTCGTTTGCAACAGAAGCGAAGATCCAGCAACACATAAGAAAGGAACATCTGGAGGCATCGAAAGCTTCTATCGAGGCGTTACGATGTCACCTGTGTCTGTTTGAAGCTAGCAGTCCATTACAGTTGCAGAGCCATTTGATAGAACACACTTTTGCAGGATGTGCAGCTCTTAGTTGCTACATTTGCCAATCACTCTTCACTGCACCTATTGGTCTTCAGAACCATATGCTCCAAGAGCACGGCCTGGGCGCTCGTCCATACGACTGTTCTCAGTGCACGCTGAAATTCTTCTTCAGGGCTGAGCTAGACCATCATATGTTAACATTTCACCGACTCGGGGAAATGCCTTCACCCGGTGGAAACGCACAGGACATCGTCGAGACGAAAACGAAAGACACTGAAGAAAAAACCTACAACGAAGGAGTAACGGTGAAAGAAGAACTACTTCCGGATGCCGGAGACGAGGAAGAAGAGATCAACGTGGACGAGCAAGTGGAAGAAAATGATCGAAAAGTAGACAAGCGTTCGTTAATCGAAACGAAATTAAAAATTGAGCTCGAGGAAGAAACTGTTTCTGAAAAAATGCAATCGTGA
Protein Sequence
MLFKGNSSRLELLIGKIQAHKEPTQEEQHKSKEALGTGSSSWQSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNTDGNNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSQGTTKLQEIDYGRRSVSSHSTSSPPVPSSPSPSLNLALNPKTGLKSSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRSNEQIAYQREKNLDRPKGTSKEHEKKYQEDAEGSIEKDHYENAFTCSQCTMKFSTLGSLRDHLISIHRTDGFGSTLMMCPLCGIPCTSAAAYAEHYVLQHCENRRVGPLEAREYIDSKMNGSYDCKSSRSQKCREQTSSEPADLTSKHSTTTESNYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDVVRHPCPKCEAIFQDREDMLVHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVPNNENSPGNAPGEGKSFFRSESEMANHVRNVHAPPTVSSNSPVARSPASTPGITGNSGPRCVFCGICCSSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHIAQAHHSSDHQGAVRSSSRENGRIGKPPRLQEEAKSQKRGRSPASSNNNSLNQRDNNNKRPNYTNTSSQQCDLCERGEFTNEAELQAHKKLAHSTAKLQNKSISNLSMTCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLTTESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGSHSVGSSPSPNQKSQSPNCCLCLRDYSADDFVNLPPNHISGGGQSLRVCKSCYIRHSQGLPILNTPYEPLRSKCDGPWISSNKDGQWDGSRDRREPESRFKEDRNEVNDNKRCQDCGVKFEGSEEAEKHRMMEHEKAATASNTYTCIQCQTSFATEAKIQQHIRKEHLEASKASIEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRLGEMPSPGGNAQDIVETKTKDTEEKTYNEGVTVKEELLPDAGDEEEEINVDEQVEENDRKVDKRSLIETKLKIELEEETVSEKMQS