Basic Information

Insect: Bombus cullumanus
Gene Symbol: znf423
Assembly: GCA_014737535.1
Location: JACXIX010000039.1:4801960-4823869[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 7.2e-06 0.00067 20.0 1.5 1 23 92 114 92 114 0.98

2 18 0.21 20 5.9 4.1 1 23 120 142 120 142 0.98

3 18 2.6e-07 2.4e-05 24.5 4.3 1 23 148 170 148 170 0.99

4 18 0.00019 0.018 15.5 0.2 1 23 176 198 176 198 0.99

5 18 6.6e-05 0.0062 17.0 0.8 1 23 350 373 350 373 0.96

6 18 0.36 34 5.2 0.0 2 23 384 406 383 406 0.88

7 18 1.3 1.2e+02 3.5 0.3 3 23 469 489 467 489 0.95

8 18 0.0018 0.17 12.5 0.6 1 23 501 523 501 523 0.97

9 18 0.012 1.1 9.8 0.3 1 23 532 555 532 555 0.92

10 18 3.2 3e+02 2.2 0.2 1 23 560 583 560 583 0.91

11 18 0.2 19 6.0 0.8 2 23 657 678 657 678 0.96

12 18 0.0045 0.42 11.2 0.1 1 23 683 706 683 707 0.94

13 18 1 98 3.8 0.1 2 23 771 794 770 794 0.83

14 18 0.0002 0.019 15.4 1.0 2 23 810 832 809 832 0.96

15 18 0.036 3.3 8.4 1.0 1 23 841 864 841 864 0.93

16 18 1.1 1e+02 3.7 0.4 2 23 1092 1113 1091 1113 0.94

17 18 0.59 56 4.5 0.1 2 23 1122 1144 1121 1144 0.93

18 18 0.019 1.8 9.2 3.1 1 23 1151 1174 1151 1174 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	7.2e-06	0.00067	20.0	1.5	1	23	92	114	92	114	0.98
2	18	0.21	20	5.9	4.1	1	23	120	142	120	142	0.98
3	18	2.6e-07	2.4e-05	24.5	4.3	1	23	148	170	148	170	0.99
4	18	0.00019	0.018	15.5	0.2	1	23	176	198	176	198	0.99
5	18	6.6e-05	0.0062	17.0	0.8	1	23	350	373	350	373	0.96
6	18	0.36	34	5.2	0.0	2	23	384	406	383	406	0.88
7	18	1.3	1.2e+02	3.5	0.3	3	23	469	489	467	489	0.95
8	18	0.0018	0.17	12.5	0.6	1	23	501	523	501	523	0.97
9	18	0.012	1.1	9.8	0.3	1	23	532	555	532	555	0.92
10	18	3.2	3e+02	2.2	0.2	1	23	560	583	560	583	0.91
11	18	0.2	19	6.0	0.8	2	23	657	678	657	678	0.96
12	18	0.0045	0.42	11.2	0.1	1	23	683	706	683	707	0.94
13	18	1	98	3.8	0.1	2	23	771	794	770	794	0.83
14	18	0.0002	0.019	15.4	1.0	2	23	810	832	809	832	0.96
15	18	0.036	3.3	8.4	1.0	1	23	841	864	841	864	0.93
16	18	1.1	1e+02	3.7	0.4	2	23	1092	1113	1091	1113	0.94
17	18	0.59	56	4.5	0.1	2	23	1122	1144	1121	1144	0.93
18	18	0.019	1.8	9.2	3.1	1	23	1151	1174	1151	1174	0.97

Sequence Information

Coding Sequence: ATGTTGTTTAAGGGAAACAGTTCGAGATTAGAGCTATTGATAGGAAAAATTCAGGCCCACAAGGAACCTTCTCGAGATGAACAGGCCAAGTCGAAAGAGGCCTTGGGCACCGGAAGTTCGTCATGGCAGAGCGAGGATGGCGGTGCAAACTCGCGACGTGGCGGAGAGACGCCGTCTTCTTGTGCGACGCCGACATCGGCGAGCTTCCCGTCGGAGCCCGAGGTCGACGCCGACGTTGGTGTCAACGCCGACGGAACCAACGCTACCGCACCATATCCTTGTCAATTCTGTGACCGCACATTTCCTCGACTAAGCTACCTGAAGAAGCACGAACAGAGCCACGGAGATCAAATGCCATACAAATGCAACTGGTGTGCCAGATTATTCAAACATAAACGCAGTAGAGATCGACACGTGAAGCTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGACGCTGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACTCACGACACCCAGAAGCCGTATCAGTGCACAGCATGTTCCAGAGGCTACAACACAGCAGCCGCTCTAACATCGCACATGCAGTCTCACAAAAAACAATCCCAAGGAACTTCCAGGCTTCAAGACATTGATTATGGTAGAAGAAGCGTGTCTTCTCATAGTACATCATCTCCACCAGTACCAAGCTCCCCATCGCCATCTTTAAACCTTTTGTTGAATCCAAAGGCTGGCTTAAAAGGTTCCCAAGGAAGTGCTTCGACGACTCCAATTTTGAGTTCACCGTTAAAATTAGCTTGCATGTACTGTACCAGAGATTCCTTTAGTTGCATGCAACAGCTGCAAATGCACGTGCATACTATGCATCAGGCTATCCTTAGTGGAGAAACTGTTGCAGTATCCCCATCAACAAATAGAACCAACGAACAGATGAGTTATCAACGTGAGAAAACTCTGGATAGACGAGAAGTATCGTCTAAAGAACAGGAAAGAAAGTATCAGGATGATTCGGAGAGATCTATAGAGAAAGATCACTATGAAAATACATTTACATGCAATCAGTGTACTATGAAGTTCTCTACGCTAGACTCTTTGAGAGATCATCTGATCTCAATTCATAGAACCGATGGTTTTAGTTCCACTTTAATGATGTGCCCTCTCTGCGGCATTCCCTGTGCTTCTGCAGCAGCCTACGCGGAGCACTATGTCCTCCAACATTGCGAGAATCGAAGAGTAGATCCACTGGAGGTTAAAAGTTATATAGATTCCAAGATGAATGGGAGCAACGAAACTAAGAGTCCCAGGAATCAGAAATATAGGGAGCAAGCTTCTTCCGAGCCAGCTGATTTGACCAACAAGCATTCCACCAATACGGTCAGCAATTATACAGCTGGTACGCTATTTTGTGGACAATGTAGAGCTGCATTGAAAGACTTCGAGTCATTCAGAGAACACCTAGCTAGACACCTTCAGGCTGATCATAGAAACGACGTTATTAGACATCCTTGTCCAAAGTGTGAAGCTACTTTTCAAGATAGGGAAAACATGTTGGTACACTTGACGAAGCACTATTTGAGTCAGATTAGTAAAGAATATGCTTGCGGCGCTTGCAAGAAGCTGTATCCCCATCCGGACCTCCTCCAAAGACATTTACTTGACAGCCATGCTCATCATCTGTATAGATGCGCGCTGTGCAGAGACACTTTTGATTCTAGAGTGGCAATACAGGTCCATTTCGCTGTAAAACACAGCCAAGAATGCAGTATTTATAGGTGCAATGCTTGCACAGTGTCTAATAATGAAAATTCACCAGGAAATGCGCCAGGCGAGGGTAAAAGCTTCTTCAGAAGTGAATCCGAAATGGCAAGCCATGTGAGAAATGTTCATGCACCTCCTACAGTGTCTAACAACAATCCTGCCGTTACAAGCCCGGCCTCCACTCCGGGAATAACTGGAAATTCAGGACCAAGATGCGTTTTCTGTGGAACTTACTGCAGCTCTGAGCTGGAGCTACAGCTCCACTTGGCTAGCCACTCTGCTAATTTGTACAGGTGTCCAATTTGTAGAGAGGGATTTGCTGTGGAGTTTTTACTGGACAGGCATATTGCTCAAGTGCATCATTCTAGCGATCATCAAGGTGCTATAAGGAATAATTCTCGGGAGAATGGAAGGATTGATAGACTGCCCAGATTACAGGAGGAAGGCAAATCTCAAAAGAGAGGCCGCTCTCCAGCCTCCAGTAACAACAATTCTCTGAACCAACGCGATAACAATAATAAACGTGCACATTACCCAAATCCATCTGCTCAGCAGTGTGATCTCTGTGAAAGGGGAGAGTTTTCCAACGAGGCGGAACTGCAAGCCCACAAGAAGCTTGCTCACACTCCATCCAAGCTTCCAAACAAGTCCATATCAAATCTCAGCATGTCTTGCGCATATTGCGGGGAAGTATGCCGTTCTAGAACTGACCTTGAGTCCCACACAAGGATCCAACATGCATCGAACGAACCCGGTGGTCGGCACAAGTGTAACATATGCGACGAAGTCTGTCCATCAGGGGCAACCCTTGCAGAGCATAAATTGCAGAAACACTGCAAGATTCAATTAAGTGACACATGCATCGTTTGTCGAGGAAATCTAGCTTCGGAGTCACAGTTTCTGGAACATGTGCAAAGACATAGCCTGGAGAACGTGGATCCTCAGCAAAGATTAGATGGTTCTCTTCCCCATCTGCCTGCAGCTTGCGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAGTGTCGTCTTCACGCCAGACACCACTTGAGAGCTTCTACTGGTTCTCACAGTGTAACATCCAGCCCCAGCCCCAATCAAAAGAACCAGAATCCTAGCTGTTGCCTTTGTTTAAGAGATTATTTAGCTGATGACTTTGTCAATTTGCCTCCAAGTCATATAACCGGTGGAGGACAGTCTTTAAGGGTCTGCAAGTCGTGCTACATTCGTCACTCTCAGGGTTTACCTATCTTGAATTCACCTTATGAGCCTGCTAGATCTAAATGTGACGGTACTTGGACATCCAATAACAAAGATGGACAATGGGATGGATCAAGGGATACATGGGAGTCAGAGAACAGATTTAAGGAAGACAGAAACGAGAAACCTGGATCTATGCCGGACACGTGTACGTGTATAGAGTGTCAGATGTCGTTGCCAACAGAAGCAAAAATTCAACAGCATGTAAAGAAGGAACAGCTGGAGATGTCGGGAAAGGCTTCCATAGAGGCGTTACGATGTCATCTGTGTCTTTTCGAAGCTAGCAGTCCCTTACAATTGCAAAGCCATTTGATAGAGCACACTTTTGCAGGATGTGCCGCTCTCAGCTGTTACATTTGCCAGTCTCTCTTCACTGCTCCTATCGGCCTCCAGAGCCATATGCTTCAAGAGCATGGCCTGGGTGCTCGTCCCTACGATTGTTCTCAGTGCACGCTTAAGTTCTTCTTCAGAGCAGAATTGGACCATCACATGCTAACATTTCATCGACCTGGAGATGCGTGTTCAACGGATGACAAGGCAGAAAATACCGGGGAAACGAAAGCAAGAGACGCTGAGGAAAGGAACTGCGGCGAAGAAATAACCATAAAGGAAGAAATAGTTTCAGAAATGGTTGCAGACGAAGAAGAAGAAATCAACGTGGACGAACAAGTGGAAGAGAACGATGAAAAGGCGAACAAGCAAACAGAAATTGAGACGAAATTAAAAACTGAACTTGTGGAGGAATCTGTTCCAGAAAAGATGAAATCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSRDEQAKSKEALGTGSSSWQSEDGGANSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGTNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYKCNWCARLFKHKRSRDRHVKLHTGDRRYRCTHCDAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKQSQGTSRLQDIDYGRRSVSSHSTSSPPVPSSPSPSLNLLLNPKAGLKGSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRTNEQMSYQREKTLDRREVSSKEQERKYQDDSERSIEKDHYENTFTCNQCTMKFSTLDSLRDHLISIHRTDGFSSTLMMCPLCGIPCASAAAYAEHYVLQHCENRRVDPLEVKSYIDSKMNGSNETKSPRNQKYREQASSEPADLTNKHSTNTVSNYTAGTLFCGQCRAALKDFESFREHLARHLQADHRNDVIRHPCPKCEATFQDRENMLVHLTKHYLSQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECSIYRCNACTVSNNENSPGNAPGEGKSFFRSESEMASHVRNVHAPPTVSNNNPAVTSPASTPGITGNSGPRCVFCGTYCSSELELQLHLASHSANLYRCPICREGFAVEFLLDRHIAQVHHSSDHQGAIRNNSRENGRIDRLPRLQEEGKSQKRGRSPASSNNNSLNQRDNNNKRAHYPNPSAQQCDLCERGEFSNEAELQAHKKLAHTPSKLPNKSISNLSMSCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLASESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGSHSVTSSPSPNQKNQNPSCCLCLRDYLADDFVNLPPSHITGGGQSLRVCKSCYIRHSQGLPILNSPYEPARSKCDGTWTSNNKDGQWDGSRDTWESENRFKEDRNEKPGSMPDTCTCIECQMSLPTEAKIQQHVKKEQLEMSGKASIEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQSHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRPGDACSTDDKAENTGETKARDAEERNCGEEITIKEEIVSEMVADEEEEINVDEQVEENDEKANKQTEIETKLKTELVEESVPEKMKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00232173;
80% Identity: -