Basic Information

Insect: Bombus campestris
Gene Symbol: znf423
Assembly: GCA_905333015.1
Location: HG995145.1:3809043-3820743[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.21 17 6.0 4.1 1 23 54 76 54 76 0.98

2 17 2.6e-07 2e-05 24.7 4.3 1 23 82 104 82 104 0.99

3 17 0.00019 0.015 15.6 0.2 1 23 110 132 110 132 0.99

4 17 6.6e-05 0.0052 17.1 0.8 1 23 284 307 284 307 0.96

5 17 0.36 28 5.3 0.0 2 23 318 340 317 340 0.88

6 17 1.3 1e+02 3.6 0.3 3 23 403 423 401 423 0.95

7 17 0.0018 0.14 12.6 0.6 1 23 435 457 435 457 0.97

8 17 0.012 0.96 9.9 0.3 1 23 466 489 466 489 0.92

9 17 3.2 2.5e+02 2.3 0.2 1 23 494 517 494 517 0.91

10 17 0.091 7.2 7.2 0.9 2 23 591 612 591 612 0.97

11 17 0.0045 0.35 11.3 0.1 1 23 617 640 617 641 0.94

12 17 1 82 3.9 0.1 2 23 705 728 704 728 0.83

13 17 0.0002 0.016 15.5 1.0 2 23 744 766 743 766 0.96

14 17 0.036 2.8 8.5 1.0 1 23 775 798 775 798 0.93

15 17 1.1 85 3.8 0.4 2 23 1011 1032 1010 1032 0.94

16 17 0.59 47 4.6 0.1 2 23 1041 1063 1040 1063 0.93

17 17 0.019 1.5 9.3 3.1 1 23 1070 1093 1070 1093 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.21	17	6.0	4.1	1	23	54	76	54	76	0.98
2	17	2.6e-07	2e-05	24.7	4.3	1	23	82	104	82	104	0.99
3	17	0.00019	0.015	15.6	0.2	1	23	110	132	110	132	0.99
4	17	6.6e-05	0.0052	17.1	0.8	1	23	284	307	284	307	0.96
5	17	0.36	28	5.3	0.0	2	23	318	340	317	340	0.88
6	17	1.3	1e+02	3.6	0.3	3	23	403	423	401	423	0.95
7	17	0.0018	0.14	12.6	0.6	1	23	435	457	435	457	0.97
8	17	0.012	0.96	9.9	0.3	1	23	466	489	466	489	0.92
9	17	3.2	2.5e+02	2.3	0.2	1	23	494	517	494	517	0.91
10	17	0.091	7.2	7.2	0.9	2	23	591	612	591	612	0.97
11	17	0.0045	0.35	11.3	0.1	1	23	617	640	617	641	0.94
12	17	1	82	3.9	0.1	2	23	705	728	704	728	0.83
13	17	0.0002	0.016	15.5	1.0	2	23	744	766	743	766	0.96
14	17	0.036	2.8	8.5	1.0	1	23	775	798	775	798	0.93
15	17	1.1	85	3.8	0.4	2	23	1011	1032	1010	1032	0.94
16	17	0.59	47	4.6	0.1	2	23	1041	1063	1040	1063	0.93
17	17	0.019	1.5	9.3	3.1	1	23	1070	1093	1070	1093	0.97

Sequence Information

Coding Sequence: ATGGAGTTTAAAATAGCGCAAAAGTCGCAGCCTCACTTTGATCAACTTCATCGAGGATTGATATTAGCTCTTCACGGTTCGATGTCCAGTGTAATTTCTATTCTGGTAAGCTCAATGTCCAGTATAACTGCTATTCTGAGCCACGGAGATCAAATGCCATACAAATGCAACTGGTGTGCCAGATTATTCAAACATAAACGCAGTAGAGATCGACACGTGAAACTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGACGCTGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACTCACGACACCCAGAAGCCGTATCAGTGCACAGCATGTTCCAGAGGCTACAACACAGCAGCCGCTCTAACATCCCACATGCAGTCTCACAAAAAACAATCCCAAGGAACTTCCAGACTTCAAGACATTGATTATGGTAGAAGAAGCGTGTCTTCTCATAGTACATCATCTCCACCAGTACCAAGCTCCCCATCGCCATCTTTAAACCTTTTATTGAATCCAAAGGCTGGCTTAAAAAGTTCCCAAGGAAGTGCTTCGACGACTCCAATTTTGAGTTCACCATTAAAATTAGCTTGCATGTACTGTACCAGAGATTCCTTTAGTTGCATGCAACAGCTACAAATGCACGTGCATACTATGCATCAGGCTATCCTTAGTGGAGAAACTGTTGCGGTATCCCCATCAACAAATAGAACCAACGAACAGATGAGTTATCAACGTGAGAAGACTCTGGATAGACCAGAAGGATCATCTAGAGAACAGGAAAGAAAGTATCATGATGATTCAGAGAGATCTATAGAGAAAGATCACtatgaaaatacatttacatgcaatcagtgTACTATGAAGTTCTCTACGTTAGACTCTTTGAGAGATCATCTGATCTCAATTCATAGAACCGATGGTTTTAGTTCTACTTTAATGATGTGCCCTCTCTGCGGCATTCCTTGTGCTTCTGCAGCAGCCTACGCGGAGCATTATGTCCTTCAACATTGTGAAAATCGAAGAGTAGATCCATTGGAGgttaaaagttatatagaTTCCAAGATGAATGGAAGCAACGAAACTAAGAGTCCCAGGAATCAGAAATATAGGGAGCAAACTTCTTCTGAGCCAGCTGATTTGACCAACAAGCATTCCACCAGTACAGTCAGCAATTATACATCTGGTACGCTATTTTGTGGACAATGTAGAGCTGCATTGAAAGACTTCGAGTCATTCAGAGAACACCTAGCCAGACATCTTCAGGCTGATCATAGAAATAATGTTGTTAGACATCCTTGTCCAAAGTGTGAAGCTACTTTTCAAGATAGGGAGAACATGTTAGTACACTTGACGAAGCACTATTTGAATCAGATTAGCAAAGAATATGCTTGCGGTGCTTGCAAGAAGCTATATCCCCATCCGGACCTTCTTCAAAGACATTTACTTGACAGCCATGCTCATCATCTCTATAGATGCGCCCTGTGCAGGGACACTTTTGATTCTAGAGTGGCAATACAGGTCCATTTCGCTGTAAAACACAGTCAAGAATGCAGTATTTATAGGTGCAATGCTTGCACAGTGtctaataatgaaaattcacCGGGAAATGCGCCAGGGGAGGGTAAAAGCTTCTTCAGAAGTGAATCCGAAATGGCAAGCCATGTGAGAAATGTTCATGCACCTCCTACAGTGTCTAACAACAATCCTGCCGTTACAAGCCCGGCCTCCACTCCGGGAATAACTGGAAATTCAGGGCCAAGATGCGTTTTCTGTGGAACTTACTGCAGTTCTGAGCTAGAACTACAGCTCCACTTGGCTACCCACTCTGCTAATTTGTACAGGTGCCCAATTTGTAGAGAGGGATTTGCTGTGGAATTTTTACTAGACAGGCATATTGCTCAAGTGCATCATTCTAGTGATCATCAAGGTGCTATAAGGAATAATTCTCGGGAGAATGGAAGGATTGATAGATTACCCAGATTACAGGAAGAAGGCAAATCTCAAAAGAGAGGCCGCTCTCCAGCCTCCAGTAACAACAATTCTCTGAATCAACacgataacaataataaacgtcCACATTACTCAAATCCATCTGCTCAGCAGTGTGATCTCTGTGAAAGGGGAGAGTTTTCCAACGAGGCGGAACTGCAAGCCCACAAGAAACTTGCCCACATTCCATCCAAGCTTCCAAACAAGTCCATATCAAATCTCAGCATGTCTTGCGCATATTGCGGGGAAGTATGTCGTTCTAGAACTGACTTGGAGTCCCACACAAGGATCCAACATGCATCGAACGAACCTGGTGGTCGGCACAAGTGTAACATATGCGACGAAGTCTGTCCATCAGGGGCAACTCTTGCAGAACATAAATTGCAGAAACACTGCAAGATTCAATTAAGTGACACATGTATCGTTTGTCGAGGAAATCTAGCTTCGGAATCACAGTTTCTGGAACATGTGCAAAGACATAGCCTGGAGAACGTGGATCCTCAGCAAAGATTAGATGGTTCTCTTCCCCATCTCCCTGCAGCTTGCGTAGTTTGTAGACAGACATTAATCAGTGATTTGGAGTGTCGTCTTCACGCCAGACACCACTTGAGAACTTCTACTGGTTCTCACAGTGTCACATCCAGCCCCAGTCCCAACCAAAAGAACCAGAATCCTAGCTGTTGCCTTTGTTTAAGAGATTATTTAGCTGATGACTTTGTCAATTTGCCTCCAAGTCATATAAGCGGTGGAGGACAGTCTTTAAGGGTCTGCAAGTCATGCTACATTCGTCACTCTCAGGGTTTACCTATCTTGAATTCACCTTATGAGCCTGCTAGATCTAAATGTGACGGTACCTGGACATCCAATAACAAAGATGGACAATGGGATGGATCAAGAGATACATGGGAGTCAGAGAACAGATTTAAGGAAGACAGAAATGAGATGTCGTTGCCAACAGAAGCAAAAATTCAACAGCATGTAAAGAAGGAACAACTGGAGATGTCAGGAAAGACTTCCATAGAGGCGTTACGATGTCACCTGTGTCTTTTTGAAGCTAGCAGTCCCTTACAATTGCAAAGCCATTTGATAGAGCACACTTTTGCAGGATGTGCCGCTCTCAGCTGTTACATTTGCCAGTCTCTCTTCACTGCTCCTATCGGCCTCCAGaGCCATATGCTTCAAGAGCATGGTCTGGGTGCTCGTCCCTACGATTGTTCTCAGTGCACGCTCAAGTTCTTCTTCAGAGCAGAATTGGACCATCACATGCTAACATTTCATCGATCTGGAGATGCGTGTTCACCGGATGACAAGGCGGAAAATACTGGAGAAACGAAAGCAAGAGACGCTGAAGAAAGGAACTGCGGCGAAGAAATAACCGTAAAGGAAGAAATAGTTTCAGAAATAGTTgcagacgaagaagaagaaatcaaCGTGGATGAACAAGTGGAAGAGAACGATCAAACGGCGAACAAGCAAACAGAAATTGAGACGAAATTAAAAACTGAACTTGTGGAGGACTCTGTTCCAGAAAAGATGAAATCGTGA
Protein Sequence: MEFKIAQKSQPHFDQLHRGLILALHGSMSSVISILVSSMSSITAILSHGDQMPYKCNWCARLFKHKRSRDRHVKLHTGDRRYRCTHCDAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKQSQGTSRLQDIDYGRRSVSSHSTSSPPVPSSPSPSLNLLLNPKAGLKSSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRTNEQMSYQREKTLDRPEGSSREQERKYHDDSERSIEKDHYENTFTCNQCTMKFSTLDSLRDHLISIHRTDGFSSTLMMCPLCGIPCASAAAYAEHYVLQHCENRRVDPLEVKSYIDSKMNGSNETKSPRNQKYREQTSSEPADLTNKHSTSTVSNYTSGTLFCGQCRAALKDFESFREHLARHLQADHRNNVVRHPCPKCEATFQDRENMLVHLTKHYLNQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECSIYRCNACTVSNNENSPGNAPGEGKSFFRSESEMASHVRNVHAPPTVSNNNPAVTSPASTPGITGNSGPRCVFCGTYCSSELELQLHLATHSANLYRCPICREGFAVEFLLDRHIAQVHHSSDHQGAIRNNSRENGRIDRLPRLQEEGKSQKRGRSPASSNNNSLNQHDNNNKRPHYSNPSAQQCDLCERGEFSNEAELQAHKKLAHIPSKLPNKSISNLSMSCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLASESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRTSTGSHSVTSSPSPNQKNQNPSCCLCLRDYLADDFVNLPPSHISGGGQSLRVCKSCYIRHSQGLPILNSPYEPARSKCDGTWTSNNKDGQWDGSRDTWESENRFKEDRNEMSLPTEAKIQQHVKKEQLEMSGKTSIEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQSHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRSGDACSPDDKAENTGETKARDAEERNCGEEITVKEEIVSEIVADEEEEINVDEQVEENDQTANKQTEIETKLKTELVEDSVPEKMKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00232173;
80% Identity: -