Basic Information

Insect: Nomia melanderi
Gene Symbol: znf423
Assembly: GCA_003710045.1
Location: NW:520745-544325[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 5.6e-06 0.00034 20.0 1.5 1 23 92 114 92 114 0.98

2 22 0.32 19 5.0 3.9 1 23 120 142 120 142 0.97

3 22 6.9e-07 4.2e-05 22.8 4.3 1 23 148 170 148 170 0.99

4 22 0.00015 0.009 15.5 0.2 1 23 176 198 176 198 0.99

5 22 0.00027 0.017 14.7 0.6 1 23 354 377 354 377 0.95

6 22 0.28 17 5.2 0.0 2 23 388 410 387 410 0.88

7 22 0.14 8.4 6.2 0.1 3 23 473 493 472 493 0.97

8 22 0.002 0.12 12.0 0.3 1 23 505 527 505 527 0.97

9 22 0.0095 0.58 9.8 0.3 1 23 536 559 536 559 0.92

10 22 2.5 1.5e+02 2.2 0.2 1 23 564 587 564 587 0.91

11 22 9.2 5.6e+02 0.4 0.2 10 23 619 633 618 633 0.93

12 22 0.15 9.2 6.0 2.0 2 23 661 682 661 682 0.96

13 22 0.0015 0.09 12.3 0.2 1 23 687 710 687 711 0.95

14 22 2.2 1.4e+02 2.4 0.1 2 23 774 797 773 797 0.81

15 22 0.00014 0.0083 15.6 1.0 2 23 813 835 812 835 0.96

16 22 0.028 1.7 8.3 1.0 1 23 844 867 844 867 0.93

17 22 5.1 3.1e+02 1.2 0.1 2 23 875 896 874 896 0.94

18 22 0.0003 0.018 14.5 0.1 2 23 1058 1080 1057 1080 0.97

19 22 0.07 4.2 7.1 0.3 1 23 1090 1113 1090 1113 0.96

20 22 0.32 19 5.0 0.3 2 23 1125 1146 1124 1146 0.95

21 22 0.32 19 5.0 0.1 2 23 1155 1177 1154 1177 0.93

22 22 0.071 4.3 7.1 3.0 1 23 1184 1207 1184 1207 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	5.6e-06	0.00034	20.0	1.5	1	23	92	114	92	114	0.98
2	22	0.32	19	5.0	3.9	1	23	120	142	120	142	0.97
3	22	6.9e-07	4.2e-05	22.8	4.3	1	23	148	170	148	170	0.99
4	22	0.00015	0.009	15.5	0.2	1	23	176	198	176	198	0.99
5	22	0.00027	0.017	14.7	0.6	1	23	354	377	354	377	0.95
6	22	0.28	17	5.2	0.0	2	23	388	410	387	410	0.88
7	22	0.14	8.4	6.2	0.1	3	23	473	493	472	493	0.97
8	22	0.002	0.12	12.0	0.3	1	23	505	527	505	527	0.97
9	22	0.0095	0.58	9.8	0.3	1	23	536	559	536	559	0.92
10	22	2.5	1.5e+02	2.2	0.2	1	23	564	587	564	587	0.91
11	22	9.2	5.6e+02	0.4	0.2	10	23	619	633	618	633	0.93
12	22	0.15	9.2	6.0	2.0	2	23	661	682	661	682	0.96
13	22	0.0015	0.09	12.3	0.2	1	23	687	710	687	711	0.95
14	22	2.2	1.4e+02	2.4	0.1	2	23	774	797	773	797	0.81
15	22	0.00014	0.0083	15.6	1.0	2	23	813	835	812	835	0.96
16	22	0.028	1.7	8.3	1.0	1	23	844	867	844	867	0.93
17	22	5.1	3.1e+02	1.2	0.1	2	23	875	896	874	896	0.94
18	22	0.0003	0.018	14.5	0.1	2	23	1058	1080	1057	1080	0.97
19	22	0.07	4.2	7.1	0.3	1	23	1090	1113	1090	1113	0.96
20	22	0.32	19	5.0	0.3	2	23	1125	1146	1124	1146	0.95
21	22	0.32	19	5.0	0.1	2	23	1155	1177	1154	1177	0.93
22	22	0.071	4.3	7.1	3.0	1	23	1184	1207	1184	1207	0.97

Sequence Information

Coding Sequence: ATGTTGTTCAAGGGAAACAGCTCCAGGCTGGAGCTGTTGATCGGGAAGATACAGGCTCATAAGGAACCTTCTCAGGATGATCACCACAAATCGAAAGAAGCGCTCGGGACCGGAAGTTCGTCCTGGCACAGCGAGGATGGTGGACCAAACTCGCGGCGTGGCGGAGAGACACCGTCGTCCTGTGCGACTCCAACATCCGCCAGCTTCCCGTCGGAACCCGAAGTCGATGCCGACGTTGGCGTCAACGCCGACGGGAACAACGCCACCGCGCCTTATCCTTGTCAATTCTGCGACCGCACTTTTCCGCGACTGAGCTACCTGAAGAAGCACGAACAGAGCCACGGCGATCAAATGCCCTACCGATGCAGCTGGTGCGCCAGACTGTTCAAGCACAAACGCAGCAGAGATCGACACGTGAAGCTGCACACGGGAGATCGAAGATATCGATGCACGCACTGCGAGGCTGCTTTCTCCAGGAGCGATCACCTAAAGATCCACATGAAGACCCATGACACCCAGAAGCCATACCAATGCACGGCATGTTCCCGCGGCTACAACACCGCGGCCGCATTGACATCGCACATGCAGTCGCACAAGAAGCACCACCACCAGTCCCAGGGAGCTACGAAACTGCAGGACGTGGAGTACGGTCGACGAAGCGTGTCCTCGCACAGCACGTCTTCGCCGCCGGTGCCAAGTTCTCCATCGCCATCTCTGAATCTAACGCTGAATCCGAAGACTGGTTTGAAGAGTTCTCACGGCAGCGCGTCCACAACGCCGATCCTGAGTTCACCGTTGAAGCTGGCGTGCATGTACTGCACCAGGGACTCGTTCAGTTGCATGCAACAGCTGCAGATGCACGTGCACACGATGCACCAGGCGATCTTGAGCGGCGAGGCCGTGGCAGTGCCACCGTCGCCCAGCAGGAGCACCGATCAGGCGAACTACCAGCGGGAGAAAGGATCGCTGGCTCGATCGGAAGGCTCTTCGAAAGACCACGAGAGGAAGTATCAAGAAGATACCGAGAGATCCGTCGAGAAGGATCAGTACGAGAACGCGTTCACTTGCAACCAATGCACCATGAAGTTCTCCACGTTGGCGACACTTAGAGACCACCTGGTCTCGATCCACAGGACGGACGGTTTCGGGTCAGCGCTGATGATGTGTCCTCTCTGCGGGATCCCTTGCGCCTCCGCCGCGGCTTACGCGGAGCACTACGTCTTGCAGCACTGCGAGAACCGCAGAATAGGTCCTTTAGAAGGCGCGGAGTACGCGGACGCAAAGATGAATGGGAGTTACGGCGACTCGAAGAGTTCTAGAAGCCAGAAGCCTAGGGAATCGGTCTCCGAGCCGGCTGATCTGACCAGCAAACATTCCAGACCGACTGAGAACAGTTACACTGCAGGAACGTTGCTCTGCGGACAATGCGGAGCAGCGTTGAAGGACTTCGAATCGTTCAGGGAGCATCTAGCTAGGCATCTGCAAGCTGATCATAGGAATGACGCCATGAGACATCCGTGTCCTAAGTGCGAAGCGAGCTTCCAGGACAGAGAGGACATGCTGGCGCATCTGACGAAGCATTATCTGGGCCAGATCAGCAAGGAGTACGCTTGTGGAGCCTGCAAGAAGCTGTACCCTCATCCAGACCTTTTGCAGAGGCACCTGCTCGACAGCCATGCGCACCATTTGTACAGATGCGCCTTATGCAGGGACACTTTCGACTCCAGAGTAGCGATACAGGTCCACTTCGCGGTGAAGCATAGTCAGGAGTGCAGGATCTATCGGTGCAACGCCTGCACAGTGCCCAATAATGAAAACTCGCCGGGAAACACGCCGGGGGAGGGTAGAAGCTTCTTCAGGAGCGAATCGGAGATGGCGAATCATGTCAGGAACGTCCACGCGCCTTCCACGGTTTCTAACAGCAGTCCCGTGGCTAGGAGTCCAGCATCAACACCCGGAATCACTGGGAACGCTGTGCCGAGATGCGTTTTCTGTGGGATCTGCTGCAACTCTGAGTTGGAGCTGCAACTTCACTTGGCCAGCCACTCGACTAGCTTGTACAGATGTCCTATCTGCAGGGAGGGCTTCGCCGTGGAATTCTTGCTCGACAGACACATGGCCCAAGCTCATCATTCGAGCGATCATCAGGCTGTGAGGAGCAGCTCCAGGGAAAATGGACGGATAGGGAGACCAGCCAGGACGCAGGAAGAGCCTAAGTCCCAGAAAAGAGGTCGTTCTCCAGCGTCCAGCAACAACAATTCCCTGAACCAACGGGACAACAACAACAAACGGCCGAACTACACCAACACAGGGGGGCAGCAGTGCGAGCTCTGCGAGAGAGGAGAGTTCGCGAATGAGGCAGAGCTGCAGGCTCACAAGAAACTGGCTCACACCCCGGCAAAGCTGCAGAACAAGTCCGTGTCCAACCTCAGCATGACCTGTGCGTACTGTGGTGAAGTGTGTCGCTCTAGGACTGAACTGGAATCCCATACTAGGATCCAGCACGCCTCCAATGAACCTGGAGGTCGTCACAAGTGCAACATCTGCGACGAGGTGTGTCCTTCCGGAGCAACATTAGCTGAGCACAAACTGCAGAAGCATTGCAAGATTCAGCTAAGCGACACCTGCGTCGTTTGCCGAGGAAACTTAACGTCGGAAGCCCAGTTCCTCGAGCACGTGCAGAGACACAGCCTGGAGAATGTTGATCCTCAACAGAGACTGGACGGCTCTCTCCCTCATCTGCCTGCGGCCTGTGTCGTCTGCAGGCAGACGTTGATCAGTGACTTAGAGTGTCGTCTGCATGCCAGGCATCACCTCAGGTCTCCCACTGGCCCCCAGAGTGCAACGTCCAGCCCCAGTCCCAATCAAAAGAGTCAGAGTCCTGGTTGCTGCCTCTGCTTAAGAGACTATTCCGCGGATGACTTCGTCAGTTTGCCACCGAGCCATATCAGCGGCGGTGGACAGTCCCTGAGGGTTTGCAAGTCCTGTTACATTCGCCACTCTCAGGGTCTACCCATCTTGAATTCGCCGTATGAGCACGCTAGGGGGAAGAGCGATAGAGGATGGACTTCGAGTGGTAAAGAGTCTCAATGGGATGGGTCTAGGGATAGATGGGAGCCTGATAGAGTCTTCAAAGCTGAAGACAGGACGGACGAGACTAGTGATAATAAAAGATGTCAGGATTGTGGGGTGAAGTTTGAGGACCCTGAAGAGGTTGAGAAACACAGACTTACGGAACACGAGAAGGTTGGATCTGGATCGAACACTTACACTTGCATACAGTGTCAGATGTCGTTTCCATCTGAAGCAAAGATACAGCAGCATGTAAGAAAGGAGCATTTAGAAGCCACTGGGAAATCTATTGATGCACTGCGGTGTCACCTGTGTCTCTACGAAGCTAGCAGTCCCCTGCAGTTGCAGAGCCATTTGATAGAGCACACTTTCGCCGGGTGCGCTGCTCTTAGTTGTTACATTTGTCAGTCTCTTTTCACCGCTCCTATTGGTCTTCAGAATCACATGCTACAAGAACATGGTCTGGGTGCCCGTCCGTACGACTGCTCAAAGTGCACTCTGAAGTTCTTCTTCAGGGCAGAACTGGATCATCATGTGTTAACGTTCCATCGACCTGGAGAGGTATCTCCGCCTCATGAAGCTGTTCAGAACGTCGTAGAAATGAAAGCTACAGATCCTGAAGAGCAGATCTGTGATGATGGGATCACGGTGAAAGAGGAACTGTTACCAGATGCTgcagaagaagaggaagagatCAATGTCGACGGGCAAATGGAACATGAGGAGGAAGGCAAACAGGATGCAAATCAGAAACTCAAAACCGAAATTGACACGGAACCTGCTGTTCCGGAGAAAACTGAATCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQDDHHKSKEALGTGSSSWHSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGNNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHHQSQGATKLQDVEYGRRSVSSHSTSSPPVPSSPSPSLNLTLNPKTGLKSSHGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGEAVAVPPSPSRSTDQANYQREKGSLARSEGSSKDHERKYQEDTERSVEKDQYENAFTCNQCTMKFSTLATLRDHLVSIHRTDGFGSALMMCPLCGIPCASAAAYAEHYVLQHCENRRIGPLEGAEYADAKMNGSYGDSKSSRSQKPRESVSEPADLTSKHSRPTENSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDAMRHPCPKCEASFQDREDMLAHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVPNNENSPGNTPGEGRSFFRSESEMANHVRNVHAPSTVSNSSPVARSPASTPGITGNAVPRCVFCGICCNSELELQLHLASHSTSLYRCPICREGFAVEFLLDRHMAQAHHSSDHQAVRSSSRENGRIGRPARTQEEPKSQKRGRSPASSNNNSLNQRDNNNKRPNYTNTGGQQCELCERGEFANEAELQAHKKLAHTPAKLQNKSVSNLSMTCAYCGEVCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCVVCRGNLTSEAQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRSPTGPQSATSSPSPNQKSQSPGCCLCLRDYSADDFVSLPPSHISGGGQSLRVCKSCYIRHSQGLPILNSPYEHARGKSDRGWTSSGKESQWDGSRDRWEPDRVFKAEDRTDETSDNKRCQDCGVKFEDPEEVEKHRLTEHEKVGSGSNTYTCIQCQMSFPSEAKIQQHVRKEHLEATGKSIDALRCHLCLYEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCTLKFFFRAELDHHVLTFHRPGEVSPPHEAVQNVVEMKATDPEEQICDDGITVKEELLPDAAEEEEEINVDGQMEHEEEGKQDANQKLKTEIDTEPAVPEKTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: -
80% Identity: -