Basic Information

Insect: Bombus impatiens
Gene Symbol: znf423
Assembly: GCA_000188095.4
Location: NT:288539-426315[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 6.3e-06 0.00039 19.9 1.8 1 23 145 167 145 167 0.98

2 18 0.18 11 5.9 4.1 1 23 209 231 209 231 0.98

3 18 2.2e-07 1.4e-05 24.5 4.3 1 23 237 259 237 259 0.99

4 18 0.00016 0.01 15.4 0.2 1 23 265 287 265 287 0.99

5 18 5.7e-05 0.0035 16.9 0.8 1 23 439 462 439 462 0.96

6 18 0.31 19 5.1 0.0 2 23 473 495 472 495 0.88

7 18 1.1 68 3.4 0.3 3 23 558 578 556 578 0.95

8 18 0.0016 0.097 12.4 0.6 1 23 590 612 590 612 0.97

9 18 0.01 0.65 9.8 0.3 1 23 621 644 621 644 0.92

10 18 2.8 1.7e+02 2.1 0.2 1 23 649 672 649 672 0.91

11 18 0.17 11 5.9 0.8 2 23 746 767 746 767 0.96

12 18 0.0039 0.24 11.1 0.1 1 23 772 795 772 796 0.94

13 18 0.9 56 3.7 0.1 2 23 860 883 859 883 0.83

14 18 0.00017 0.011 15.4 1.0 2 23 899 921 898 921 0.96

15 18 0.031 1.9 8.3 1.0 1 23 930 953 930 953 0.93

16 18 0.93 58 3.6 0.4 2 23 1166 1187 1165 1187 0.94

17 18 0.51 32 4.5 0.1 2 23 1196 1218 1195 1218 0.93

18 18 0.017 1 9.1 3.1 1 23 1225 1248 1225 1248 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	6.3e-06	0.00039	19.9	1.8	1	23	145	167	145	167	0.98
2	18	0.18	11	5.9	4.1	1	23	209	231	209	231	0.98
3	18	2.2e-07	1.4e-05	24.5	4.3	1	23	237	259	237	259	0.99
4	18	0.00016	0.01	15.4	0.2	1	23	265	287	265	287	0.99
5	18	5.7e-05	0.0035	16.9	0.8	1	23	439	462	439	462	0.96
6	18	0.31	19	5.1	0.0	2	23	473	495	472	495	0.88
7	18	1.1	68	3.4	0.3	3	23	558	578	556	578	0.95
8	18	0.0016	0.097	12.4	0.6	1	23	590	612	590	612	0.97
9	18	0.01	0.65	9.8	0.3	1	23	621	644	621	644	0.92
10	18	2.8	1.7e+02	2.1	0.2	1	23	649	672	649	672	0.91
11	18	0.17	11	5.9	0.8	2	23	746	767	746	767	0.96
12	18	0.0039	0.24	11.1	0.1	1	23	772	795	772	796	0.94
13	18	0.9	56	3.7	0.1	2	23	860	883	859	883	0.83
14	18	0.00017	0.011	15.4	1.0	2	23	899	921	898	921	0.96
15	18	0.031	1.9	8.3	1.0	1	23	930	953	930	953	0.93
16	18	0.93	58	3.6	0.4	2	23	1166	1187	1165	1187	0.94
17	18	0.51	32	4.5	0.1	2	23	1196	1218	1195	1218	0.93
18	18	0.017	1	9.1	3.1	1	23	1225	1248	1225	1248	0.97

Sequence Information

Coding Sequence: ATGTCCAGGAGGAAGCAGGCAAAGCCTCGATCTCTAAAACGAGACGAAGAGTGGGACGACGGGAACGAGCAAAATGTCCTGGAGGTAACCGAGCAGGATAATGAGACAACGGGAATTAAACaGGATgacgaggaggaagaggaagaagaggagctGCAGAGAGCGTTCAGTCAACATTCGGAGGAGTACGCACAAGAAGGAAGGCCATCGTCAGTTCAAGGACTAGATCTGGAGAATCAGAACAGCCTCGACAGCGAGGCCTTGGGCACCGGAAGTTCGTCATGGCAGAGCGAGGATGGCGGTGCAAACTCGCGACGTGGCGGAGAGACGCCGTCTTCTTGTGCGACGCCGACATCGGCGAGCTTCCCGTCGGAGCCCGAGGTCGACGCCGACGTTGGTGTCAACGCCGACGGAACCAACGCTACCGCACCTTATCCTTGTCAATTCTGTGACCGCACATTTCCTCGACTTAGCTACCTGAAGAAGCACGAACAGCGTCACTTTGATCAACTTCATCGAGGATTGATATTAGCTCTTCACGGTTCGATGTCCAGTGTAATTTCTATTCTGGTAAGCTCAATGTCCAGTGTAACTGCTATTCCGAGCCACGGAGATCAAATGCCATACAAATGCAACTGGTGTGCCAGATTGTTCAAACATAAACGCAGTAGAGATCGACACGTGAAACTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGACGCTGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACTCACGACACCCAGAAGCCGTATCAGTGCACAGCATGCTCCAGAGGCTACAACACAGCAGCCGCTCTAACATCTCACATGCAGTCTCACAAGAAACAATCTCAAGGAACTGCCAGGCTTCAAGACATTGATTATGGTAGAAGAAGCGTGTCTTCTCATAGTACATCATCTCCACCAGTACCAAGCTCCCCATCGCCATCTTTAAACCTTTTGTTGAATCCAAAGGCTGGCTTAAAAAGTTCCCAAGGAAGTGCTTCGACGACTCCAATTTTGAGTTCACCGTTGAAATTAGCCTGCATGTACTGTACCAGAGACTCCTTTAGTTGCATGCAACAGCTGCAAATGCACGTGCATACTATGCATCAGGCTATCCTTAGTGGAGAAACCGTTGCAGTATCCCCATCAACAAATAGAACCAACGAACAGATGAGTTATCAACGTGATAAAACTCTGGATAGACCAGAAGGATCATCCAAAGAACAGGAAAGAAAGTATCAGGATGATTCAGAGAGATCTATAGAGAAAGATCactatgaaaatacatttacatGCAATCAGTGTACTATGAAGTTCTCTACGTTAGACTCTTTGAGAGATCATCTGATCTCAATTCATAGAACCGATGGTTTTAGTTCTACTTTAATGATGTGCCCTCTCTGCGGCATTCCTTGTGCTTCTGCAGCAGCCTACGCGGAGCACTATGTCCTCCAACATTGTGAGAATCGAAGAGTAGATCCATTGGAGGTTAAAAGTTATATAGATTCCAAGATGAATGGAAGCAACGAAACTAAGAGTCCCAGGAATCAGAAATATAGAGAGCAAACTTCTTCTGAGCCAGCTGATTTGACCAACAAGCATTCCACCAGTACAGCCAGCAATTATACAGCTGGTACGCTATTTTGTGGACAATGTAGAGCTGCATTGAAAGACTTCGAGTCATTCAGAGAACACCTAGCTAGACATCTTCAGGCTGATCATAGAAATGACGTTATTAGACATCCTTGTCCAAAGTGTGAAGCCACTTTTCAAGATAGGGAGAACATGTTGGTACACTTGACAAAGCATTATTTGAGTCAGATTAGTAAAGAATATGCTTGCGGTGCTTGCAAGAAGCTGTATCCCCATCCGGACCTCCTCCAAAGACATTTACTTGACAGCCATGCTCATCATCTCTATAGATGCGCCCTGTGCAGAGACACTTTCGATTCTAGAGTGGCAATACAGGTCCATTTCGCTGTAAAACACAGTCAAGAATGCAGTATTTATAGGTGCAATGCTTGCACAGTGtctaataatgaaaattcgcCAGGAAATGCGCCAGGGGAGGGTAAAAGCTTCTTCAGAAGCGAATCCGAAATGGCAAGCCATGTGAGAAATGTTCATGCACCTCCTACAGTTTCTAACAACAATCCTGTCGTTACAAGCCCGGCCTCCACTCCGGGAATAACTGGAAATTCAGGACCAAGATGCGTTTTCTGTGGAACTTACTGCAGTTCTGAGCTGGAACTACAACTCCACTTGGCTAGCCACTCTGCTAATTTATACAGGTGCCCAATTTGTAGAGAGGGATTTGCTGTGGAGTTTTTACTAGACAGGCATATTGCTCAAGTGCATCATTCTAGTGATCATCAAGGTGCTATAAGGAATAATTCTCGGGAGAATGGAAGGATTGATAGACTACCCAGATTACAGGAAGAAGGCAAATCTCAAAAGAGAGGCCGCTCTCCAGCCTCCAGTAACAACAATTCTGTGAACCAGCgcgataacaataataaacgtCCACATTACTCAAATCCATCTGCTCAGCAGTGTGATCTCTGTGAAAGGGGAGAGTTTTCCAACGAGGCCGAACTGCAAGCCCACAAGAAACTTGCTCACACTCCATCCAAGCTTCCAAACAAGTCCATATCGAATCTCAGCATGTCTTGCGCATATTGCGGGGAAGTATGTCGTTCTAGAACTGACCTGGAGTCCCACACAAGGATTCAACATGCATCGAATGAACCTGGTGGTCGGCACAAGTGTAACATATGCGACGAAGTCTGTCCATCAGGGGCAACTCTTGCAGAACATAAATTGCAGAAACACTGCAAGATTCAATTAAGCGACACATGCATCGTTTGTCGAGGAAATCTAGCTTCGGAGTCACAGTTTCTGGAACATGTGCAAAGACATAGCCTAGAGAACGTGGATCCTCAGCAAAGATTAGATGGTTCTCTTCCCCATCTCCCTGCAGCTTGTGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAGTGTCGTCTTCACGCCAGACACCATTTAAGAGCTTCTACTGGTTCTCACAGTGTAACATCCAGCCCCAGCCCCAACCAAAAGAACCAGAATCCTAGCTGTTGCCTTTGTTTAAGAGATTATTTAGCTGATGACTTTGTCAATTTGCCTCCAAGTCATATAAGCGGCGGAGGACAGTCTTTAAGGGTCTGCAAGTCATGCTACATTCGTCACTCTCAGGGTTTACCTATCTTGAATTCACCTTATGAGCCTGCTAGATCTAAATGTGACGGTACTTGGACATCCAATAACAAAGATGGACAATGGGATGGATCAAGGGATACATGGGAGTCAGAGAACAGATTTAAGGAAGACAGAAACGAGATGTCGTTGCCAACAGAAGCAAAAATTCAACAGCATATAAAGAAGGAACAGCTGGAGATGTCGGGAAAGACTTCCATAGAGGCGTTACGATGTCATCTGTGTCTTTTTGAAGCTAGCAGTCCCTTACAATTGCAAAGCCATTTGATAGAGCACACTTTTGCAGGATGTGCCGCTCTCAGCTGTTACATTTGTCAGTCTCTCTTCACAGCTCCTATCGGCCTCCAGagCCATATGCTTCAAGAGCATGGCCTGGGTGCTCGTCCCTACGATTGTTCTCAGTGCACGCTCAAGTTCTTCTTCAGAGCAGAATTGGACCATCACATGCTAACATTTCATCGACCTGGGGATGCGTGTTCACCGGATGACAAGGCAGAAAATACTGGAGAAACGAAAGCAAGAGACGCTGAGGAAAGGAACTGCGGTGAAGAAATAACCGTAAAGGAAGAAATAGTTTCAGAAATAGTTgcagacgaagaagaagaaatcaaCGTGGACGAACAAGTGGAAGAGAACGATCAAAAGGCGAACAAGGAAACAGAAATTGAGACGAAATTGAAAACTGAACTTGTGGAGGAATCTGTTCCAGAAAAGATGAAATCGTGA
Protein Sequence: MSRRKQAKPRSLKRDEEWDDGNEQNVLEVTEQDNETTGIKQDDEEEEEEEELQRAFSQHSEEYAQEGRPSSVQGLDLENQNSLDSEALGTGSSSWQSEDGGANSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGTNATAPYPCQFCDRTFPRLSYLKKHEQRHFDQLHRGLILALHGSMSSVISILVSSMSSVTAIPSHGDQMPYKCNWCARLFKHKRSRDRHVKLHTGDRRYRCTHCDAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKQSQGTARLQDIDYGRRSVSSHSTSSPPVPSSPSPSLNLLLNPKAGLKSSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRTNEQMSYQRDKTLDRPEGSSKEQERKYQDDSERSIEKDHYENTFTCNQCTMKFSTLDSLRDHLISIHRTDGFSSTLMMCPLCGIPCASAAAYAEHYVLQHCENRRVDPLEVKSYIDSKMNGSNETKSPRNQKYREQTSSEPADLTNKHSTSTASNYTAGTLFCGQCRAALKDFESFREHLARHLQADHRNDVIRHPCPKCEATFQDRENMLVHLTKHYLSQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECSIYRCNACTVSNNENSPGNAPGEGKSFFRSESEMASHVRNVHAPPTVSNNNPVVTSPASTPGITGNSGPRCVFCGTYCSSELELQLHLASHSANLYRCPICREGFAVEFLLDRHIAQVHHSSDHQGAIRNNSRENGRIDRLPRLQEEGKSQKRGRSPASSNNNSVNQRDNNNKRPHYSNPSAQQCDLCERGEFSNEAELQAHKKLAHTPSKLPNKSISNLSMSCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLASESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGSHSVTSSPSPNQKNQNPSCCLCLRDYLADDFVNLPPSHISGGGQSLRVCKSCYIRHSQGLPILNSPYEPARSKCDGTWTSNNKDGQWDGSRDTWESENRFKEDRNEMSLPTEAKIQQHIKKEQLEMSGKTSIEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQSHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRPGDACSPDDKAENTGETKARDAEERNCGEEITVKEEIVSEIVADEEEEINVDEQVEENDQKANKETEIETKLKTELVEESVPEKMKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00232173;
80% Identity: -