Basic Information

Insect: Megalopta genalis
Gene Symbol: znf423
Assembly: GCA_011865705.1
Location: NW:6266368-6370447[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 6.9e-06 0.00037 19.9 1.5 1 23 146 168 146 168 0.98

2 21 0.39 21 4.9 3.9 1 23 174 196 174 196 0.97

3 21 8.5e-07 4.6e-05 22.8 4.3 1 23 202 224 202 224 0.99

4 21 0.00018 0.0098 15.4 0.2 1 23 230 252 230 252 0.99

5 21 0.00034 0.018 14.6 0.6 1 23 408 431 408 431 0.95

6 21 3.2 1.7e+02 2.1 0.0 2 21 442 461 441 464 0.82

7 21 0.17 9.1 6.1 0.1 3 23 527 547 526 547 0.97

8 21 0.0024 0.13 11.9 0.3 1 23 559 581 559 581 0.97

9 21 0.0042 0.22 11.1 0.5 1 23 590 613 590 613 0.92

10 21 3.1 1.6e+02 2.1 0.2 1 23 618 641 618 641 0.91

11 21 0.19 10 6.0 2.0 2 23 715 736 715 736 0.96

12 21 0.0032 0.17 11.5 0.2 1 23 741 764 741 765 0.94

13 21 2.7 1.5e+02 2.3 0.1 2 23 828 851 827 851 0.81

14 21 0.00017 0.009 15.5 1.0 2 23 867 889 866 889 0.96

15 21 0.034 1.8 8.3 1.0 1 23 898 921 898 921 0.93

16 21 7.5 4e+02 0.9 0.3 2 23 929 950 928 950 0.93

17 21 0.00015 0.0079 15.7 0.1 2 23 1112 1134 1111 1134 0.93

18 21 0.086 4.6 7.0 0.3 1 23 1144 1167 1144 1167 0.96

19 21 0.39 21 4.9 0.3 2 23 1180 1201 1179 1201 0.95

20 21 0.39 21 4.9 0.1 2 23 1210 1232 1209 1232 0.93

21 21 0.087 4.7 7.0 3.0 1 23 1239 1262 1239 1262 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	6.9e-06	0.00037	19.9	1.5	1	23	146	168	146	168	0.98
2	21	0.39	21	4.9	3.9	1	23	174	196	174	196	0.97
3	21	8.5e-07	4.6e-05	22.8	4.3	1	23	202	224	202	224	0.99
4	21	0.00018	0.0098	15.4	0.2	1	23	230	252	230	252	0.99
5	21	0.00034	0.018	14.6	0.6	1	23	408	431	408	431	0.95
6	21	3.2	1.7e+02	2.1	0.0	2	21	442	461	441	464	0.82
7	21	0.17	9.1	6.1	0.1	3	23	527	547	526	547	0.97
8	21	0.0024	0.13	11.9	0.3	1	23	559	581	559	581	0.97
9	21	0.0042	0.22	11.1	0.5	1	23	590	613	590	613	0.92
10	21	3.1	1.6e+02	2.1	0.2	1	23	618	641	618	641	0.91
11	21	0.19	10	6.0	2.0	2	23	715	736	715	736	0.96
12	21	0.0032	0.17	11.5	0.2	1	23	741	764	741	765	0.94
13	21	2.7	1.5e+02	2.3	0.1	2	23	828	851	827	851	0.81
14	21	0.00017	0.009	15.5	1.0	2	23	867	889	866	889	0.96
15	21	0.034	1.8	8.3	1.0	1	23	898	921	898	921	0.93
16	21	7.5	4e+02	0.9	0.3	2	23	929	950	928	950	0.93
17	21	0.00015	0.0079	15.7	0.1	2	23	1112	1134	1111	1134	0.93
18	21	0.086	4.6	7.0	0.3	1	23	1144	1167	1144	1167	0.96
19	21	0.39	21	4.9	0.3	2	23	1180	1201	1179	1201	0.95
20	21	0.39	21	4.9	0.1	2	23	1210	1232	1209	1232	0.93
21	21	0.087	4.7	7.0	3.0	1	23	1239	1262	1239	1262	0.97

Sequence Information

Coding Sequence: ATGTCCAGGAGGAAGCAGGCGAAGCCGCGATCTCTCAAACGAGACGAGGAGTGGGAGGACGGGAACGAGCAGAATGTCCTGGAGGTAACCGAGCAGGATAATGGGACAACGGGAATTAAGCaggacgaggaggaggaggaggaggaagaggaggagctGCAGCGGGCGTTCAGTCGTCATTCCGAGGACTATCTCCAAGATGGCAGGCCGTCGTCGACGCAGGGTCCGGACCTAGAGAACCACAACAGCCTCGACAGCGAAGCACTCGGAACCGGAAGTTCGTCTTGGCACAGCGAGGATGGCGGGCCAAACTCGCGGCGAGGAGGAGAAACGCCTTCGTCTTGCGCGACGCCAACGTCAGCTAGCTTCCCGTCGGAACCCGAAGTCGACGCCGACGTCGGCGTCAACGCCGACGGCAATAACGCGACCGCCCCTTATCCATGCCAATTCTGTGACCGCACTTTTCCGAGGCTTAGCTACCTGAAGAAGCACGAACAGAGCCACGGCGATCAAATGCCGTATCGGTGCAGCTGGTGCGCCAGACTATTCAAACACAAACGCAGCAGAGATCGACACGTGAAGCTGCACACCGGAGATCGAAGATATCGATGCACGCACTGCGAGGCAGCTTTCTCCAGGAGCGACCACCTGAAAATCCACATGAAGACCCACGACACCCAGAAGCCGTACCAATGCACGGCCTGCTCCCGAGGCTACAACACCGCGGCCGCCTTGACGTCGCACATGCAGTCCCACAAGAAGCACCACCATCAGTCTCAGGGCGCGACGAAGCTGCAGGACGTGGACTACGGTCGTCGCAGCGTGTCCTCCCACAGCACGTCCTCGCCGCCAGTTCCCAGTTCCCCGTCGCCTTCGTTGAACCTCGCCCTGAACCCGAAAGCCGGGTTGAAAAGCTCGCACGGCAGCGCGTCGACCACGCCGATCCTGAGCTCTCCGCTGAAGCTGGCCTGCATGTACTGCACCAGGGACTCGTTCAGCTGCATGCAGCAGCTGCAGATGCACGTGCACACGATGCACCAGGCGATTCTCAGCGGCGAGAGCGTGGCGGTGCCGCCGTCGCCCAGCAGGAACGCCGAGCCGGCCGGTTACCAGCGAGAGAAAGGATCGCTTCGGTCGGAGGGGTCCTCGAAGGACCACCACGAGAGGAAGTACCAAGAGGAGGCGGACAGATCGACGGAGAAGGACCAGTACGAGAACGCGTTCACGTGCAACCAGTGTACCATGAAGTTCTCGACGTTGGCCACGCTGAGGGACCACCTGGTCTCGATCCACAGAACCGACGGATTCGGGTCCGCGCTGATGATGTGCCCCCTTTGCGGGATCCCGTGCGCCTCTGGCGCGGCCTACGCCGAGCACTACGTCCTCCAGCACTGCGAGAACCGGAGACTGGGTCCTATGGACGGCGTGGAGTACGGGGACGCGAAGATGAACGGTAGCTACGGCGACTCGAAGACATCCCGAAGCCAGAAGACACGGGACTCGATGTCGGAGCCGGCCGATTTGACCAGCAAACATTCCAGACCCACCGAGAGCAGCTACACCGCCGGCACCCTGCTCTGCGGACAGTGCGGCGCGGCTTTGAAGGACTTCGAGTCGTTCAGGGAGCATCTGGCCAGGCATCTGCAGGCCGATCACAGGAACGACGCCATGAGGCACCCTTGTCCAAAGTGCGAGGCCAGCTTCCAGGACAGGGAGGACATGCTGGCGCATCTCACCAAGCATTATCTCGGCCAGATCAGCAAGGAGTACGCTTGCGGGGCTTGCAAGAAGCTGTACACTCATCCGGATCTGCTGCAGAGGCACCTGCTCGACAGCCACGCGCATCATCTGTACAGATGCGCCTTGTGCAGGGACACTTTCGATTCCAGGGTCGCGATACAGGTGCATTTCGCGGTGAAGCACAGCCAGGAGTGCAGGATCTACAGATGCAACGCGTGCACCGTCTCCAATAACGAGAACTCGCCCGGCAACGCGCCCGGCGAAGGGCGAAGCTTCTTCAGGAGCGAAGCGGAGATGGCGAACCACGTCAGGAACGTGCACGCGCCATCCACTGTCTCCAATAGCAGCCCCGTGGCCAGGAGTCCCGCCTCCACCCCCGGCGTCACCGGCAACGCTGTCCCCAGATGCGTGTTCTGCGGGATCTGCTGCAACTCGGAGCTGGAGCTGCAGCTTCACCTGGCCAGTCACTCGACCAGCTTGTACAGGTGTCCTATCTGCAGGGAAGGCTTCGCCGTGGAGTTCCTGCTGGACAGACACATGGTCCAGGCCCATCATTCCAGCGACCATCAGGCCGTACGCAGCAGCTCCAGGGAGAACGGGAGGGTCGGGCGACCGCCTAGAACGCAGGAAGAGCCGAGGTCCCTGAAGAGGGGCCGTTCCCCGGCCTCCAGCAACAACAACTCCTTGAACCAACGGGACAACAACAACAAGCGGCCGAATTTAAGCAGCACCGGGGGCCAGCAGTGCGAGCTCTGCGAGAGAGGAGAGTTCGCGAACGAGGCGGAGCTGCAGGCACACAAGAAGCTGGCCCACGCCCCTGCGAAGCTTCAGACCAAGTCTCTGTCCAGCCTCAGCATGACCTGCGCCTACTGCGGCGAGGTCTGTCGCTCCAGAACCGAGCTGGAATCCCACACGCGGATCCAGCACGCCTCCAACGAGCCCGGCGGCAGGCACAAGTGCAACATCTGCGACGAGGTGTGCCCCTCCGGAGCGACTTTGGCCGAGCACAAGTTGCAGAAGCACTGCAAGATCCAGCTGAGCGACACCTGCGTCGTCTGCCGCGGGAACCTGGCCACCGAGGCCCACTTCCTCGAGCACGTGCAGAGACACAGTCTGGAGAACGTCGACCCTCAGCAGCGACTCGACGGCTCCCTTCCTCATCTCCCCGCCGCCTGTGTCGTCTGCAGACAGACCTTGATCAGCGATCTGGAGTGCCGTCTCCACGCCAGGCATCATCTCAGATCGTCCACCAGCTCGCAGAGCACCGCGTCCAGTCCTAGCCCGAACCAGAAGAGCCAGAGTCCAGGGTGCTGTCTCTGTCTGAGAGACTACTCGGCCGACGACTTCGTCAGCCTGCCTCCTAGCCACATCACCGGCGGAGGACAGTCCTTGAGGGTCTGCAAGTCCTGCTACATTCGCCACTCACAGGGTCTGCCCATCTTAAATTCGCCCTACGAGCACGCCAGAGGGAAGAACGACAGAGGCTGGATCCCCAGCAGCAAAGAGTCGCAATGGGACGGGTCTCGAGATAGATGGGAGTCCGATAGGGTCTTCAAAGCCGAGGACAGGGTCGACGAGCAGGGTGATAATAAAAGATGTCAAGACTGCGGGGTGAAGTTCGAAGATCCTGAGGAATTGGAGAAACACAGGCTCGCGGAGCACGACAAAGTTGCAGCAGGGTCCAACACGTACACCTGTATACAGTGTCAGATGTCGTTCCCGTCGGAAGCGAAGATACAGCAACACGTCAGAAAGGAACACCTAGAGGCGACGGGAAAGACTTCTATCGATGCTCTACGATGCCATCTGTGTCTCTACGAGGCTAGCAGCCCCCTGCAGTTGCAAAGCCACCTGATAGAGCACACCTTCGCCGGCTGCGCTGCTCTCAGCTGTTACATTTGCCAGTCCCTTTTCACTGCTCCGATCGGTCTTCAGaaccACATGCTGCAAGAACATGGTCTTGGTGCCCGACCCTATGATTGCTCGAAGTGCACCTTGAAGTTCTTCTTCAGGGCCGAGCTTGATCATCACGTGCTGACGTTCCATCGTCCTGGAGAAATGTCACCGCCCCACGAAACCGTGCAGAACGTCGAAatgaaagcggccgaggctgaAGAACAAAACTGCGACGACGGCATCACCGTGAAAGAGGAGATGTTGCCGGACGTTGtcgaagaagaggaggagatcAATGTTGACGGGCAGATGGAACACGAAGAGGTGGAGGAGAAGCAGGTGGAAGTGAAACAGAAGATGAAAACCGAGGTGGACGAGGAGGCTGCTCTTCCCGAGAAGACGGAATCGTGA
Protein Sequence: MSRRKQAKPRSLKRDEEWEDGNEQNVLEVTEQDNGTTGIKQDEEEEEEEEEELQRAFSRHSEDYLQDGRPSSTQGPDLENHNSLDSEALGTGSSSWHSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGNNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHHQSQGATKLQDVDYGRRSVSSHSTSSPPVPSSPSPSLNLALNPKAGLKSSHGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGESVAVPPSPSRNAEPAGYQREKGSLRSEGSSKDHHERKYQEEADRSTEKDQYENAFTCNQCTMKFSTLATLRDHLVSIHRTDGFGSALMMCPLCGIPCASGAAYAEHYVLQHCENRRLGPMDGVEYGDAKMNGSYGDSKTSRSQKTRDSMSEPADLTSKHSRPTESSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDAMRHPCPKCEASFQDREDMLAHLTKHYLGQISKEYACGACKKLYTHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSPGNAPGEGRSFFRSEAEMANHVRNVHAPSTVSNSSPVARSPASTPGVTGNAVPRCVFCGICCNSELELQLHLASHSTSLYRCPICREGFAVEFLLDRHMVQAHHSSDHQAVRSSSRENGRVGRPPRTQEEPRSLKRGRSPASSNNNSLNQRDNNNKRPNLSSTGGQQCELCERGEFANEAELQAHKKLAHAPAKLQTKSLSSLSMTCAYCGEVCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCVVCRGNLATEAHFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRSSTSSQSTASSPSPNQKSQSPGCCLCLRDYSADDFVSLPPSHITGGGQSLRVCKSCYIRHSQGLPILNSPYEHARGKNDRGWIPSSKESQWDGSRDRWESDRVFKAEDRVDEQGDNKRCQDCGVKFEDPEELEKHRLAEHDKVAAGSNTYTCIQCQMSFPSEAKIQQHVRKEHLEATGKTSIDALRCHLCLYEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCTLKFFFRAELDHHVLTFHRPGEMSPPHETVQNVEMKAAEAEEQNCDDGITVKEEMLPDVVEEEEEINVDGQMEHEEVEEKQVEVKQKMKTEVDEEAALPEKTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00184109; iTF_00183450; iTF_00865535;
80% Identity: -