Basic Information

Insect: Bombus difficillimus
Gene Symbol: znf423
Assembly: GCA_014737525.1
Location: JACXIT010000141.1:3912682-3933385[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 7.8e-06 0.00073 20.0 1.5 1 23 92 114 92 114 0.98

2 18 0.23 22 5.9 4.1 1 23 120 142 120 142 0.98

3 18 2.8e-07 2.6e-05 24.6 4.3 1 23 148 170 148 170 0.99

4 18 0.00021 0.019 15.5 0.2 1 23 176 198 176 198 0.99

5 18 2.8e-05 0.0026 18.3 0.9 1 23 350 373 350 373 0.96

6 18 0.58 54 4.7 0.1 2 23 384 406 383 406 0.88

7 18 1.4 1.3e+02 3.5 0.3 3 23 469 489 467 489 0.95

8 18 0.0018 0.17 12.6 0.8 1 23 501 523 501 523 0.97

9 18 0.013 1.2 9.8 0.3 1 23 532 555 532 555 0.92

10 18 3.5 3.3e+02 2.2 0.2 1 23 560 583 560 583 0.91

11 18 0.099 9.3 7.1 0.9 2 23 657 678 657 678 0.97

12 18 0.0049 0.46 11.2 0.1 1 23 683 706 683 707 0.94

13 18 1.3 1.2e+02 3.6 0.1 2 23 771 794 771 794 0.81

14 18 0.00022 0.021 15.4 1.0 2 23 810 832 809 832 0.96

15 18 0.039 3.6 8.4 1.0 1 23 841 864 841 864 0.93

16 18 1.2 1.1e+02 3.7 0.4 2 23 1091 1112 1090 1112 0.94

17 18 0.64 60 4.5 0.1 2 23 1121 1143 1120 1143 0.93

18 18 0.021 2 9.2 3.1 1 23 1150 1173 1150 1173 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	7.8e-06	0.00073	20.0	1.5	1	23	92	114	92	114	0.98
2	18	0.23	22	5.9	4.1	1	23	120	142	120	142	0.98
3	18	2.8e-07	2.6e-05	24.6	4.3	1	23	148	170	148	170	0.99
4	18	0.00021	0.019	15.5	0.2	1	23	176	198	176	198	0.99
5	18	2.8e-05	0.0026	18.3	0.9	1	23	350	373	350	373	0.96
6	18	0.58	54	4.7	0.1	2	23	384	406	383	406	0.88
7	18	1.4	1.3e+02	3.5	0.3	3	23	469	489	467	489	0.95
8	18	0.0018	0.17	12.6	0.8	1	23	501	523	501	523	0.97
9	18	0.013	1.2	9.8	0.3	1	23	532	555	532	555	0.92
10	18	3.5	3.3e+02	2.2	0.2	1	23	560	583	560	583	0.91
11	18	0.099	9.3	7.1	0.9	2	23	657	678	657	678	0.97
12	18	0.0049	0.46	11.2	0.1	1	23	683	706	683	707	0.94
13	18	1.3	1.2e+02	3.6	0.1	2	23	771	794	771	794	0.81
14	18	0.00022	0.021	15.4	1.0	2	23	810	832	809	832	0.96
15	18	0.039	3.6	8.4	1.0	1	23	841	864	841	864	0.93
16	18	1.2	1.1e+02	3.7	0.4	2	23	1091	1112	1090	1112	0.94
17	18	0.64	60	4.5	0.1	2	23	1121	1143	1120	1143	0.93
18	18	0.021	2	9.2	3.1	1	23	1150	1173	1150	1173	0.97

Sequence Information

Coding Sequence: ATGTTGTTTAAGGGAAACAGTTCGAGATTAGAGCTATTGATAGGAAAAATTCAGGCCCACAAGGAACCTTCTCGAGATGAACAAGCCAAGTCGAAAGAGGCCTTGGGCACCGGAAGTTCGTCATGGCAAAGCGAGGATGGCGGTGCAAACTCGCGACGTGGCGGAGAGACGCCGTCTTCTTGTGCGACGCCGACATCGGCGAGCTTCCCGTCGGAGCCCGAGGTCGACGCCGACGTTGGTGTCAACGCCGACGGAACCAACGCTACCGCACCTTATCCTTGTCAATTCTGTGACCGCACATTTCCTCGACTTAGCTACCTGAAGAAACACGAACAGAGCCACGGAGATCAAATGCCATACAAATGCAACTGGTGTGCCAGATTATTCAAACATAAACGCAGTAGAGATCGACACGTGAAACTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGACGCTGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACTCACGACACCCAGAAGCCGTATCAGTGCACAGCATGTTCCAGAGGCTACAACACAGCAGCCGCTCTAACATCCCACATGCAGTCTCACAAAAAACAATCCCAAGGAACTTCCAGGCTTCAAGACATTGATTATGGTAGAAGAAGCGTGTCTTCTCATAGTACATCATCTCCACCAGTACCAAGCTCCCCATCGCCATCTTTAAACCTTTTGTTGAATCCAAAGGCTGGCTTAAAAAGTTCCCAAGGAAGTGCTTCGACGACTCCAATTTTGAGTTCACCATTGAAATTAGCTTGCATGTACTGTACCAGAGATTCCTTTAGTTGCATGCAACAGCTGCAAATGCACGTGCATACTATGCATCAGGCTATCCTTAGTGGAGAAACTGTTGCGGTATCCCCATCAACAAATAGAACCAACGAACAGATAAATTATCAACGTGAGAAGACTCTGGATAGACCAGAAGGATCATCTAAAGAACAGGAAAGAAAGTATCAGGATGATTCAGAGAGATCTATAGAGAAAGATCACTATGAAAATACATTTACATGCAATCAGTGTACTATGAAGTTCTCTACGTCAGACTCTTTGAGAGATCATCTGATCTCGATTCATAGAACCGATGGTTTTAGTTCTACTTTAATGATGTGCCCTTTTTGCGGCATTCCTTGTGCTTCTACAGCAGCCTACGCGAATCACTATGTCCTTCGACATTGTGAGGATCGAAGAGTAGGTCCATTGGAGGTTAAAACTTATATAGATTCCAAGTTGAATGGAAGCAACGAAACTAAGAGTCCCAGGAATCAGAAATATAGGGAGCAAACTTCTTCTGAGCCAGCTGATTTGACCAACAAGCATTCCACCAGTACAGTCAGCAATTATACAGCTGGTACGCTATTTTGTGGACAATGTAGAGCTGCATTGAAAGACTTCGAGTCATTCAGAGAACACCTAGCTAAACATCTTCAGGCTGATCATAGAAATGACGTTATTAGACATCCTTGTCCAAAGTGTGAAGCTACTTTTCAAAATAGGGAGAACATGTTGGTACACTTGACGAAGCACTATTTGAATCAGATTAGTAAAGAATATGCTTGCGGTGCTTGCAAGAAGCTGTATCCCCATCCGGACCTTCTCCAAAGACATTTACTTGACAGCCATGCTCATCATCTCTATAGATGCGCCCTGTGCAGAGACACTTTTGATTCTAGAGTGGCAATACAGGTCCATTTCGCTGTAAAACACAGTCAAGAATGCAGTATTTATAGGTGCAATGCTTGCACAGTGTCTAATAATGAAAATTCACCAGGAAATGCGCCAGGGGAGGGTAAAAGCTTCTTCAGAAGTGAATCCGAAATGGCAAGCCATGTGAGAAATGTTCATGCACCTCCTACAGTGTCTAACAACAATCCTGTCGTTACAAGCCCGGCCTCCACTCCGGGAATAACTGGAAATTCAGGACCAAGATGCGTTTTCTGTGGAACTTACTGCAGTTCTGAACTGGAACTACAACTCCACTTGGCTACCCACTCTACTAATTTATACAGGTGCCCAATTTGTAGAGAGGGATTTGCTGTGGAGTTTTTACTAGACAGGCATATTGCTCAAGTGCATCATTCTAGTGATCATCAAGCTGCTATAAAGAATAGTTCTTGGGAGAATGGAAGGATTGATAGATTACCCAGATTACAGGAAGAAGGCAAATCTCAAAAGAGAGGCCGCTCTCCAGCCTCCAGTAACAACAATTCTCTGAATCAACGCGATAACAATAATAAACGTCCACATTACTCAAATCCATCTGCTCGGCAGTGTGATCTCTGTGAAAGGGGAGAGTTTTCCAACGAGGCGGAACTGCAAGCCCACAAGAAACTTGCTCACACTCCATCCAAGCTTCCAAACAAGTCCATATCAAATCTCAGCATGTCTTGCGCATATTGCGGGGAAGTATGTCGTTCTAGAACTGACCTGGAGTCCCACACAAGGATCCAACATGCATCGAACGAACCTGGTGGTCGGCACAAGTGTAACATATGCGACGAAGTCTGTCCATCAGGAGCAACTCTTGCAGAACATAAATTGCAGAAACACTGCAAGATTCAATTAAGCGACACATGCATCGTTTGTCGAGGAAATCTAGCTTCGGAGTCACAGTTTCTGGAACATGTGCAAAGACATAGCCTGGAGAACGTGGATCCTCAGCAAAGATTAGATGGTTCTCTTCCCCATCTCCCTGCAGCTTGCGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAGTGTCGTCTTCACGCCAGACACCACTTGAGAGCTTCTACTGGTTCTCACAGTGTAACATCCAGCCCCAGTCCCAATCAAAAGAACCAGAATCCTAGCTGTTGCCTTTGTTTAAGAGATTATTTAGCTGATGACTTTGTCAATTTGCCTCCAAGTCATATAAGCGGCGGAGGACAGTCTTTAAGGGTCTGCAAGTCATGCTACATTCGTCACTCTCAGGGTTTACCTATCTTGAATTCACCTTATGAGCCTGCTAGATCTAAATGTGACGGTACTTGGACATCCAATAACAAAGATGGACAATGGGATGGATCAAGGGATACATGGGAGTCAGAGAACAGATTTAAGGAAGACAGAAACGAGGTAAGTGATAACAAAAGATTGTCAGGGTTGTGGGAGTGTCAGATGTCGTTGCCAACAGAAGCACAAATTCAACAGCATGTAAAGAAGGAACAACTGGAGATGTCGGGAAAGACTTCCATAGAAGCGTTGCGATGTCATCTGTGTCTTTTTGAAGCTAGCAGTCCCTTACAATTGCAAAGCCATTTGATAGAGCACACTTTTGCAGGATGTGCCGCTCTCAGCTGTTACATTTGCCAGTCTCTCTTCACTGCTCCTATCGGCCTGCAGAGCCATATGCTTCAAGAGCATGGCCTGGGTGCTCGTCCCTACGATTGTTCTCAGTGCACGCTCAAGTTCTTCTTCAGAGCAGAATTGGACCATCACATGCTAACATTTCATCGACCTGGTGATGCGTGTTCACCGGATGACAAGGCAGAAAATACTGGAGAAACGAAAGCAAGAGACGCTGAAGAAAGGAACTGCGGCGAAGAAATAACAGTAAAGGAAGAAATAGTTTCAGAAATAGTTGCAAACGAAGAAGAAGAAATCAACGTGGATGAACAAGTGGAAGAGAACGATCAAAAGGCGAACAAGCAAACAGAAATTGAGACGAAATTAAAAACTGAACTTGTGGAGGAATCTATTCCAGAGAAGATGAAATCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSRDEQAKSKEALGTGSSSWQSEDGGANSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGTNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYKCNWCARLFKHKRSRDRHVKLHTGDRRYRCTHCDAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKQSQGTSRLQDIDYGRRSVSSHSTSSPPVPSSPSPSLNLLLNPKAGLKSSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRTNEQINYQREKTLDRPEGSSKEQERKYQDDSERSIEKDHYENTFTCNQCTMKFSTSDSLRDHLISIHRTDGFSSTLMMCPFCGIPCASTAAYANHYVLRHCEDRRVGPLEVKTYIDSKLNGSNETKSPRNQKYREQTSSEPADLTNKHSTSTVSNYTAGTLFCGQCRAALKDFESFREHLAKHLQADHRNDVIRHPCPKCEATFQNRENMLVHLTKHYLNQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECSIYRCNACTVSNNENSPGNAPGEGKSFFRSESEMASHVRNVHAPPTVSNNNPVVTSPASTPGITGNSGPRCVFCGTYCSSELELQLHLATHSTNLYRCPICREGFAVEFLLDRHIAQVHHSSDHQAAIKNSSWENGRIDRLPRLQEEGKSQKRGRSPASSNNNSLNQRDNNNKRPHYSNPSARQCDLCERGEFSNEAELQAHKKLAHTPSKLPNKSISNLSMSCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLASESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGSHSVTSSPSPNQKNQNPSCCLCLRDYLADDFVNLPPSHISGGGQSLRVCKSCYIRHSQGLPILNSPYEPARSKCDGTWTSNNKDGQWDGSRDTWESENRFKEDRNEVSDNKRLSGLWECQMSLPTEAQIQQHVKKEQLEMSGKTSIEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQSHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRPGDACSPDDKAENTGETKARDAEERNCGEEITVKEEIVSEIVANEEEEINVDEQVEENDQKANKQTEIETKLKTELVEESIPEKMKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00232173;
80% Identity: -