Basic Information

Insect: Tetragonula mellipes
Gene Symbol: znf423
Assembly: GCA_011634685.1
Location: WINE01002980.1:3277-14857[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.33 97 5.2 3.9 1 23 3 25 3 25 0.97

2 20 7.2e-07 0.00021 23.0 4.3 1 23 31 53 31 53 0.99

3 20 2e-05 0.0059 18.4 0.4 1 23 59 81 59 81 0.99

4 20 0.0004 0.12 14.3 0.9 1 23 235 258 235 258 0.95

5 20 0.089 26 7.0 0.1 2 23 269 291 268 291 0.88

6 20 0.14 42 6.3 0.1 3 23 355 375 354 375 0.97

7 20 0.038 11 8.1 0.7 1 23 386 408 386 408 0.96

8 20 0.0099 2.9 10.0 0.3 1 23 417 440 417 440 0.92

9 20 2.6 7.6e+02 2.3 0.2 1 23 445 468 445 468 0.91

10 20 3.7 1.1e+03 1.8 0.3 10 23 500 514 498 514 0.93

11 20 0.069 20 7.3 2.0 2 23 542 563 542 563 0.96

12 20 0.0068 2 10.5 0.2 1 23 568 591 568 592 0.94

13 20 0.85 2.5e+02 3.9 0.1 2 23 654 677 653 677 0.83

14 20 0.00013 0.037 15.9 1.1 2 23 693 715 692 715 0.96

15 20 0.029 8.4 8.5 1.0 1 23 724 747 724 747 0.93

16 20 2 5.9e+02 2.7 0.3 5 23 758 776 754 776 0.84

17 20 0.00083 0.24 13.3 0.3 2 23 931 953 930 953 0.95

18 20 0.87 2.5e+02 3.8 0.4 2 23 1004 1025 1003 1025 0.94

19 20 0.33 97 5.2 0.1 2 23 1034 1056 1033 1056 0.93

20 20 0.016 4.6 9.3 3.1 1 23 1063 1086 1063 1086 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.33	97	5.2	3.9	1	23	3	25	3	25	0.97
2	20	7.2e-07	0.00021	23.0	4.3	1	23	31	53	31	53	0.99
3	20	2e-05	0.0059	18.4	0.4	1	23	59	81	59	81	0.99
4	20	0.0004	0.12	14.3	0.9	1	23	235	258	235	258	0.95
5	20	0.089	26	7.0	0.1	2	23	269	291	268	291	0.88
6	20	0.14	42	6.3	0.1	3	23	355	375	354	375	0.97
7	20	0.038	11	8.1	0.7	1	23	386	408	386	408	0.96
8	20	0.0099	2.9	10.0	0.3	1	23	417	440	417	440	0.92
9	20	2.6	7.6e+02	2.3	0.2	1	23	445	468	445	468	0.91
10	20	3.7	1.1e+03	1.8	0.3	10	23	500	514	498	514	0.93
11	20	0.069	20	7.3	2.0	2	23	542	563	542	563	0.96
12	20	0.0068	2	10.5	0.2	1	23	568	591	568	592	0.94
13	20	0.85	2.5e+02	3.9	0.1	2	23	654	677	653	677	0.83
14	20	0.00013	0.037	15.9	1.1	2	23	693	715	692	715	0.96
15	20	0.029	8.4	8.5	1.0	1	23	724	747	724	747	0.93
16	20	2	5.9e+02	2.7	0.3	5	23	758	776	754	776	0.84
17	20	0.00083	0.24	13.3	0.3	2	23	931	953	930	953	0.95
18	20	0.87	2.5e+02	3.8	0.4	2	23	1004	1025	1003	1025	0.94
19	20	0.33	97	5.2	0.1	2	23	1034	1056	1033	1056	0.93
20	20	0.016	4.6	9.3	3.1	1	23	1063	1086	1063	1086	0.97

Sequence Information

Coding Sequence: ATGCCATATAGGTGCAGTTGGTGTGCCAGATTATTCAAACATAAACGCAGTAGAGATCGCCACGTGAAGCTTCATACAGGAGACCGAAGATACCGATGCACGCACTGCGAAGCTGCTTTCTCCAGAAGTGACCACTTGAAGATTCATATGAAGACGCATGACACTCAAAAGCCGTATCAGTGCACAACCTGTTCCAGAGGTTACAACACAGCAGCTGCGCTAACGTCCCACATGCAATCTCACAAGAAACATCATCAATCTCAAACATCCAAACTCCAGGACATCGACTACGGTAGAAGAAGTGTATCTTCTCACAGTACATCATCGCCGCCAATACCAAGCTCTCCATCGCCATCTCTAAATATAGTCTTAAATTCAAAAACTGGTATGAAAAATACTCAAGGAAGTGCTTCGACAACTCCGATTCTGAGCTCTCCACTGAAATTAGCTTGCATGTATTGTACCAGAGATACCTTCAGTTGCATGCAACAACTTCAGATGCACGTGCATACGATGCATCAAGCTATCTTAAGTGGAGAAACTGTTGCAGTATCTCCATCAACTAACAGAACcaatgaacaaataaattatcaGCATGGAAAAACTTTTGACAGAAAGCCAGAAGGATCGTCTAAAGAACACAAAAGGAAATATCAAGATGATTCAGAAAAATCTATTGAGAAAGATCACTATGAAAACGCATTTACATGCAGTCAATGTACTATGAGATTCTCTACGTTAAACTCATTGAGAGATCATTTGGTTTCGATTCATAGAACCGATGGTTTTTGTTCTGCTTTGATGATGTGTCCTCTTTGTGGCATTCCTTGCACTTCTGCAGCGACTTATGCAGAACACTATGTTCTCCAACACtgtgaaaatcgaagaacagGTCTCCTAGAAATTAGAGACTATACAGATTCTAAGATGAATGGAAATTATGACACCAAGAGTCAGACCAGAAGTCAGAAATGTAAGGAGCAAACGTCTTCTGAGCCAGCTGATTTGACTAACAAGCATTCCACCGgtacagaaaataattatacagctGGTACATTGTTATGTGGACAGTGTGGAGCTGCTTTAAAGGACTTTGAATCATTCAGGGAACACTTAGCTAGACATCTTCAAGCTGATCATAGAAATGATGTTAGACACCCTTGTTTAAAGTGTGAAGCCACTTTTCAAGATAGGGAAGACATGTTGGTACATTTGACGAAACATTATTTGGGCCAGATTAGTAAAGAATATGCTTGTGGCGCATGTAAAAAACTTTATCCTCATCCTGATCTTCTTCAGAGACATTTACTCGACAGTCATGCTCATCATCTCTATCGATGCGCCCTGTGCAGAGATACTTTTGATTCTAGAGTGGCAATACAGGTCCATTTTGCTGTGAAACACAGTCAAGAATGCAGAATCTATAGATGCAATGCTTGCACAGTgtctaataatgaaaattcgtcAGGAAATGCgccagaagaaggaaaaagtttCTTCCGAAGTGAGTCTGAAATGACAAACCATGTAAGAAACGTCCACGCACCTCCTACGATGTCAAATAATAGTCCTGTGGCTAGGAGTCCTGCCTCCACTCCAGGAATAACTGGAAATTCCGGACCAAGATGCGTCTTCTGTGGAATCTGTTGTAGTTCCGAGCTGGAATTACAACTCCATTTGGCCAGCCATTCTGCTAACTTGTATAGATGTCCTGTTTGTAGAGAAGGATTTgccgtggaatttttattagacaGACATATTACTCAAGCACATCATTCTAATGACCATCAGGATGTCATGAGGAGTAGAGAGAATGGAAGAATTGGTAGATTACCAAGATTACAGGAAGAGGCCAAGTCCCAGAAAAGAGGTCGCTCTCCAGCATCCAGCAATAACAACTCTCTGAATCAACGTGACAACAACAATAAACGTCCAAATTACACTAATGCATCTTCTCAACAATGCGATCTCTGCGAAAGAGGAGAGTTTTCCAACGAAGCAGAACTTCAAGCTCACAAAAAATTGGTTCACACTCCGACCAAGTTTCAAAATAAGTCTGTATCAAGTCTTAGCATGACTTGCGCATACTGTGGAGAAGTATGTCGTTCTAGAACTGATCTGGAATCTCATACAAGGATTCAACATGCATCAAGTGAACCTGGAGGACGCCACAAGTGTAATATTTGTGACGAAGTGTGTCCATCAGGAGCAACACTTGCAGAACATAAACTGCAGAAACATTGTAAGATTCAATTAAGTGACACGTGTATCGTTTGTCGAGGAAACCTATCTTCAGAATCACAGTTTCTAGAACATATGCAAAGACACAGTCTGGAGAATGTGGATCCTCAGCAAAGATTAGACGGTTCTCTTCCCCATCTTCCTGCAGCTTGTGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAATGTCGTCTCCATGCCAGACACCACTTAAAAACTTCTGGCTCTCACAGCGTAGCATCCAGCCCCAGTCCGAATCAAAAGAATCAGAGTCCAAGTTGTTGTCTTTGTTTAAGAGATTATTCAGCTGATGACTTTGTTAATTTACCTCCAAGTCATATAAGTGGAGGAGGACAGTCTTTAAAGGTTTGCAAATCTTGTTACATTCGACACTCTCAGGGTCTACCTATTTTGAATTCACCTTACGAGCCTATTAAATGTGATGCTTCTTGGACATCCAATAATAAAGATAGACAATGGGATAAATCAAAGGATAAATGGGAAACCGAGaatgaagaagataaaaatgagAGGCATGATAGCAAGAAGTGTCAAGATTGTGGGgtgaaatttgaagattctGACAAGGTGGAAAAACATAGGATAGTCGAGCATGAAAAAGTTATGAGTGGAGTTATGTTGAAcacatacacatgtatacaGTGTCAGGTAATAAAAaTGTCGTTCCCAACAGAGGCAAAGATTCAGCaacatgtaaaaaaagaacatctAGAAACATCGGGAAGGACTTCCATAGAAACATTACGATGTCATCTGTGTCTTTTTGAAGCTAGCAGTCCATTGCAATTGCAAAGTCATTTGATAGAACATACTTTCGCAGGATGTGCTGCTCTCAGTTGTTACATTTGCCAATCTCTCTTCACCGCACCTATTGGTCTTCAGAATCATATGCTTCAAGAACACGGCCTAAGTGCTCGTCCCTATGATTGTTCCCAATGTACACTTAAATTCTTCTTCAGAGCAGAACTAGATCATCATATGTTAACATTTCATCGACCGAGAGACATGCCATCACCCAGTGAAAATACACAGAATaccttcaaaataaaaaaaaaagatgccgaagaaagaaattgcgaTGAAGGAGTGActgtaaaagaagaaatggtTCCAGAAgtagcagaagaagaagaagagatcaATGTGGATGAGCAAATAGAAGAGAATGATCAAAAGGCAGATCAACAatcagaaattgaaacgaaattaaaaactgaGTTTGAGGAAGAATTTGTTTCTGAAAAAATGGAATCGTGA
Protein Sequence: MPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTTCSRGYNTAAALTSHMQSHKKHHQSQTSKLQDIDYGRRSVSSHSTSSPPIPSSPSPSLNIVLNSKTGMKNTQGSASTTPILSSPLKLACMYCTRDTFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRTNEQINYQHGKTFDRKPEGSSKEHKRKYQDDSEKSIEKDHYENAFTCSQCTMRFSTLNSLRDHLVSIHRTDGFCSALMMCPLCGIPCTSAATYAEHYVLQHCENRRTGLLEIRDYTDSKMNGNYDTKSQTRSQKCKEQTSSEPADLTNKHSTGTENNYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDVRHPCLKCEATFQDREDMLVHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSSGNAPEEGKSFFRSESEMTNHVRNVHAPPTMSNNSPVARSPASTPGITGNSGPRCVFCGICCSSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHITQAHHSNDHQDVMRSRENGRIGRLPRLQEEAKSQKRGRSPASSNNNSLNQRDNNNKRPNYTNASSQQCDLCERGEFSNEAELQAHKKLVHTPTKFQNKSVSSLSMTCAYCGEVCRSRTDLESHTRIQHASSEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLSSESQFLEHMQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLKTSGSHSVASSPSPNQKNQSPSCCLCLRDYSADDFVNLPPSHISGGGQSLKVCKSCYIRHSQGLPILNSPYEPIKCDASWTSNNKDRQWDKSKDKWETENEEDKNERHDSKKCQDCGVKFEDSDKVEKHRIVEHEKVMSGVMLNTYTCIQCQVIKMSFPTEAKIQQHVKKEHLETSGRTSIETLRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLSARPYDCSQCTLKFFFRAELDHHMLTFHRPRDMPSPSENTQNTFKIKKKDAEERNCDEGVTVKEEMVPEVAEEEEEINVDEQIEENDQKADQQSEIETKLKTEFEEEFVSEKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_01420489;
80% Identity: -