Basic Information

Insect: Apis laboriosa
Gene Symbol: znf423
Assembly: GCA_014066325.1
Location: JACEOM010001757.1:4044762-4054964[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 7.4e-06 0.0014 20.0 1.5 1 23 103 125 103 125 0.98

2 21 0.42 80 5.0 3.9 1 23 131 153 131 153 0.97

3 21 9.1e-07 0.00017 22.8 4.3 1 23 159 181 159 181 0.99

4 21 0.0002 0.037 15.5 0.2 1 23 187 209 187 209 0.99

5 21 0.00011 0.021 16.3 0.6 1 23 362 385 362 385 0.96

6 21 0.37 71 5.2 0.0 2 23 396 418 395 418 0.88

7 21 0.18 35 6.1 0.1 3 23 482 502 481 502 0.97

8 21 0.005 0.95 11.1 1.3 1 23 514 536 514 536 0.97

9 21 0.013 2.4 9.8 0.3 1 23 545 568 545 568 0.92

10 21 3.3 6.3e+02 2.2 0.2 1 23 573 596 573 596 0.91

11 21 4.7 9e+02 1.7 0.3 10 23 628 642 626 642 0.93

12 21 0.097 18 7.0 2.1 2 23 670 691 670 691 0.96

13 21 0.0083 1.6 10.4 0.1 1 23 696 719 696 720 0.94

14 21 1.1 2.2e+02 3.6 0.2 2 23 784 807 783 807 0.83

15 21 0.00016 0.031 15.7 1.1 2 23 823 845 822 845 0.96

16 21 0.037 7 8.3 1.0 1 23 854 877 854 877 0.93

17 21 0.0012 0.24 12.9 0.1 2 23 1065 1087 1064 1087 0.95

18 21 0.04 7.6 8.2 0.4 1 23 1097 1120 1097 1120 0.96

19 21 2.4 4.7e+02 2.6 0.4 2 23 1133 1154 1132 1154 0.93

20 21 0.42 80 5.0 0.1 2 23 1163 1185 1162 1185 0.93

21 21 0.02 3.8 9.2 3.1 1 23 1192 1215 1192 1215 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	7.4e-06	0.0014	20.0	1.5	1	23	103	125	103	125	0.98
2	21	0.42	80	5.0	3.9	1	23	131	153	131	153	0.97
3	21	9.1e-07	0.00017	22.8	4.3	1	23	159	181	159	181	0.99
4	21	0.0002	0.037	15.5	0.2	1	23	187	209	187	209	0.99
5	21	0.00011	0.021	16.3	0.6	1	23	362	385	362	385	0.96
6	21	0.37	71	5.2	0.0	2	23	396	418	395	418	0.88
7	21	0.18	35	6.1	0.1	3	23	482	502	481	502	0.97
8	21	0.005	0.95	11.1	1.3	1	23	514	536	514	536	0.97
9	21	0.013	2.4	9.8	0.3	1	23	545	568	545	568	0.92
10	21	3.3	6.3e+02	2.2	0.2	1	23	573	596	573	596	0.91
11	21	4.7	9e+02	1.7	0.3	10	23	628	642	626	642	0.93
12	21	0.097	18	7.0	2.1	2	23	670	691	670	691	0.96
13	21	0.0083	1.6	10.4	0.1	1	23	696	719	696	720	0.94
14	21	1.1	2.2e+02	3.6	0.2	2	23	784	807	783	807	0.83
15	21	0.00016	0.031	15.7	1.1	2	23	823	845	822	845	0.96
16	21	0.037	7	8.3	1.0	1	23	854	877	854	877	0.93
17	21	0.0012	0.24	12.9	0.1	2	23	1065	1087	1064	1087	0.95
18	21	0.04	7.6	8.2	0.4	1	23	1097	1120	1097	1120	0.96
19	21	2.4	4.7e+02	2.6	0.4	2	23	1133	1154	1132	1154	0.93
20	21	0.42	80	5.0	0.1	2	23	1163	1185	1162	1185	0.93
21	21	0.02	3.8	9.2	3.1	1	23	1192	1215	1192	1215	0.97

Sequence Information

Coding Sequence: atggaaaaatggaagaagcTGGAGAGCGAAGGATTCCCGCGAGGAATGCGCTTTTCTTCTATCCGTGAGGACGACCAGTCCTCTCTGGTGGAGGATGAACGACGACGAAGCATCTTGACAATGTTCACGGAGGCGTTGGGGACCGGAAGTTCGTCGTGGCAGAGCGAGGATGGCGGACCAAACTCGCGGCGAGGCGGCGAGACGCCCTCGTCTTGCGCGACCCCGACGTCGGCCAGTTTCCCGTCGGAGCCAGAGGTCGACGCCGACGTCGGAGTGAACGCCGACGGGAGCAACGCGACAGCCCCTTACCCTTGCCAATTCTGCGACCGCACGTTCCCCCGGCTTAGCTATCTCAAGAAGCACGAACAGAGTCACGGGGACCAAATGCCATACAGGTGCAGCTGGTGTGCCAGATTATTCAAACATAAACGCAGCAGAGATCGACACGTAAAGCTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGAGGCTGCTTTCTCCAGGAGcgaCCATCTGAAGATCCATATGAAAACTCACGACACGCAGAAACCGTATCAGTGCACGGCCTGTTCCAGAGGGTACAACACAGCAGCTGCCTTGACATCCCATATGCAATCTCACAAGAAACATCATCAATCGCAAGGATCGGCCAAGGACATCGATTACGGTAGAAGAAGCGTGTCCTCTCACAGTACATCATCGCCGCCAGTACCGAGTTCCCCATCACCGTCTTTAAACCTCTCCTTGAACCCGAAATCCGGGTTGAAAAGCTCGCAGGGCAGTGTTTCGACAACGCCGATCCTAAATTCTCCATTGAAACTTGCCTGCATGTACTGCACCAGAGATTCTTTCAACTGCATGCAACAGCTCCAGATGCACGTGCATACAATGCATCAAGCTATCTTAAGCGGCGAAACTGTTGCGGTATCTCCATCGACCAATAGAGCCAACGAACAGATTGGTTATCAACATGgtgagaaaaatttagatcGATCGGAAGGAACTTCGAAGGAGCATAATAGGAAATATCAAGATGATTCAGAGAGGTCTATGGAAAAGGATCATTATGAAAACGCGTTTACGTGCAATCAGTGTACGATGAAATTCTCCACATTAGGCTCTTTGAGAGATCACTTGATCTCGATCCATAGAACGGACAGTTTCAACTCTGCCTTGATGATGTGCCCTCTTTGCGGCATTCCCTGTGCTTCGGCAGCTGCTTACGCGGAACATTATGTTCTTCAACATtgtgaaaatcgatcgatagcTCCCCTGGAAAGTAAAGACTATATAGATGCGAAAATGAACGGAAGTTACGAGTCTAAAAGTTCCAGAAATCAGAAATCTAGAGAACAAATATCTTCTTCTGAGCCAGCAGATTTAACTAGCAAGCATACCACCACTACGGAAAACAATTATTCAGCTGGTACTCTGTTATGTGGCCAATGTGGAGCAGCTTTAAAAGACTTTGAATCTTTTAGAGAACATCTGGCTAGACACCTTCAAGCTAATCATAGAAACGATGCTGTCAGACATTCTTGTCCCAAGTGTGAGGCCACTTTTCAAGACAGGGAAGATATGTTTGTGCACTTGACAAAGCATTATCTAGGTCAGATTAGTAAAGAATATGCCTGTGGTGCCTGCAAAAAGCTCTATCCCCATCCAGATCTTCTTCAAAGGCATTTGCTCGATAGTCATGCTCACCACCTTTACAGATGCGCTCTGTGCAGAGACACTTTTGATTCCAGAGTGGCGATACAAGTCCATTTTGCTGTGAAACACAGTCAGGAGTGTAGGATCTATAGATGCAATGCTTGTACGGTGTCCAATAACGAAAATTCGCCGGGTAATGCAccaggagaaggaaaaagtttctttaGGAGTGAATCCGAGATGACAAATCATGTGAGAAATGTCCATGCACCTCCTACTGTATCAAATAACAGCCCTGTAGCCAGAAGTCCTGCAACTACTCCTGGAATAACTGGAAATTCCGGACCAAGATGTGTTTTCTGTGGAATTTGTTGTACTTCTGAACTGGAATTACAACTCCATTTGGCTAGCCATTCTGCTAATTTGTACAGATGTCCAGTTTGTAGAGAGGGATTTGCTGTAGAATTTTTGTTGGACAGGCATATTGCTCAAGCACATCATTCCAGTAATCATCAAGGTATTATTAGAAGTAGCTCTAGAGAAAATGGAAGGATTGGTAGACCGCCAAGATTGCAAGAAGAGacaaAATCTCAAAAAAGAGGTCGTTCTCCAGCATCCAGCAACAACAACACCGTAAATCAACGAGACAACAATAATAAACGTCCAAATTACTCCAATACATCTTCTCAACAGTGTGATCTCTGCGAAAGAGGGGAATTTTCTAATGAAACAGAACTCCAAGCCCACAAGAAATTGGTTCACACTCCAGCtaagtttcaaaataaatctatatcaaATCTCAGCATGACTTGTGCATATTGTGGAGAAGTATGTCGTTCTAGAACTGATCTAGAATCTCATACAAGGATTCAACATGCATCAAATGAACCTGGGGGCCGTCACAAATGCAATATTTGTGACGAAGTCTGTCCTTCAGGTGCAACTCTAGCAGAACATAAACTGCAAAAACACTGTAAAATTCAACTAAGTGACACGTGTATTGTTTGTCGAGGAAATTTATCTTCAGAATCACAATTTTTAGAACACGTTCAAAGACACAGTTTGGAAAACGTGGATCCTCAACAGAGATTAGATGGTTCTCTTCCCCATCTTCCTGCAGCGTGTGTAGTTTGCAGACAGACACTGATCAGCGATTTGGAATGTCGTCTTCATGCTAGACATCATTTGAGAGCTTCTACTGGTCCTCACAGTGTGGGATCTAGCCCTAGTCCCAACCAAAAAAATCAGAATCCAAGTTGTTGTCTTTGCTTAAGAGATTATTCTGGTGATGACTTTGTTAATTTGCCACCAAGTCATGTAAGTGGAGGAGGACAATCTTTGAGAGTCTGCAAGTCTTGCTATATTCGTCACTCTCAAGGTTTACCTATTTTGAATTCATATGAATCTGTTAGATCTAAATGTGATGATTCTTGGAcatctaataataaagatgGACAATGGGAtggatcgaaaaataaatgggAATcggagaataaatataaagaaaatagaaatggaaTGATTGATAATAAGAGATGTCAAGATTGTGGAGTGAAATTTGAAGATTCTGAAGAGGTGGAAAAACATAGGATAATAGAGCATGAGAAGACTGGAGCTGTATCTAATACATATACGTGTATACAATGTCAAATGTCATTCGCAACAGAAGCAAAGATTCAGCAgcatataaagaaagaacatTTGGAAGTATCAGAAAAAACTTCCATGGAGGCATTACGATgtcatttatgtttatttgaaGCTAATAGTCCATTACAGTTGCAAAGCCATTTGATAGAGCACACTTTTGCAGGATGTGCCGCTCTCAGCTGTTATATTTGCCAATCTCTTTTCACTGCACCTATTGGTCTTCAgaatcataTGCTTCAAGAACATGGTTTGGGTGCACGCCCATATGATTGTTCCCAGtgcacattaaaatttttcttcagagCAGAATTAGATCACCATATGTTAACATTCCATCGATCCGGAGACGTATCCTCGCCTGATGAAGATATACGAAacaatattgaaacaaaacCAAGAAACactgaagaaaataattctgatgAAAGAATAATGGTGAAAGAAGAATTGTTACCGGAAGGTgcagacgaagaagaagagatcAACGTGGATGAACAAGTAGAAGAGAACGAGCAAAAGGAAGACAAACAGTTAGAATTCgagacaaaattaaaaactgaaaccgaggaagaaaatattcttcagtCTTCCGTTTCCGAGAAAATGGAATCGTGA
Protein Sequence: MEKWKKLESEGFPRGMRFSSIREDDQSSLVEDERRRSILTMFTEALGTGSSSWQSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGSNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSQGSAKDIDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPKSGLKSSQGSVSTTPILNSPLKLACMYCTRDSFNCMQQLQMHVHTMHQAILSGETVAVSPSTNRANEQIGYQHGEKNLDRSEGTSKEHNRKYQDDSERSMEKDHYENAFTCNQCTMKFSTLGSLRDHLISIHRTDSFNSALMMCPLCGIPCASAAAYAEHYVLQHCENRSIAPLESKDYIDAKMNGSYESKSSRNQKSREQISSSEPADLTSKHTTTTENNYSAGTLLCGQCGAALKDFESFREHLARHLQANHRNDAVRHSCPKCEATFQDREDMFVHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSPGNAPGEGKSFFRSESEMTNHVRNVHAPPTVSNNSPVARSPATTPGITGNSGPRCVFCGICCTSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHIAQAHHSSNHQGIIRSSSRENGRIGRPPRLQEETKSQKRGRSPASSNNNTVNQRDNNNKRPNYSNTSSQQCDLCERGEFSNETELQAHKKLVHTPAKFQNKSISNLSMTCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLSSESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGPHSVGSSPSPNQKNQNPSCCLCLRDYSGDDFVNLPPSHVSGGGQSLRVCKSCYIRHSQGLPILNSYESVRSKCDDSWTSNNKDGQWDGSKNKWESENKYKENRNGMIDNKRCQDCGVKFEDSEEVEKHRIIEHEKTGAVSNTYTCIQCQMSFATEAKIQQHIKKEHLEVSEKTSMEALRCHLCLFEANSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRSGDVSSPDEDIRNNIETKPRNTEENNSDERIMVKEELLPEGADEEEEINVDEQVEENEQKEDKQLEFETKLKTETEEENILQSSVSEKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00142642;
80% Identity: -