Basic Information

Insect: Melipona bicolor
Gene Symbol: znf423
Assembly: GCA_030673865.1
Location: JAHYIQ010000018.1:2632248-2654195[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 9e-06 0.00099 20.0 1.5 1 23 76 98 76 98 0.98

2 20 0.51 56 5.0 3.9 1 23 104 126 104 126 0.97

3 20 1.1e-06 0.00012 22.9 4.3 1 23 132 154 132 154 0.99

4 20 7.1e-05 0.0078 17.2 0.3 1 23 160 182 160 182 0.99

5 20 0.00044 0.048 14.7 0.6 1 23 336 359 336 359 0.95

6 20 0.14 15 6.8 0.1 2 23 370 392 369 392 0.88

7 20 0.22 24 6.2 0.1 3 23 455 475 454 475 0.97

8 20 0.059 6.5 8.0 0.7 1 23 486 508 486 508 0.96

9 20 0.015 1.7 9.8 0.3 1 23 517 540 517 540 0.92

10 20 4 4.4e+02 2.2 0.2 1 23 545 568 545 568 0.91

11 20 0.11 12 7.2 2.0 2 23 642 663 642 663 0.96

12 20 0.011 1.2 10.3 0.2 1 23 668 691 668 692 0.94

13 20 0.85 94 4.3 0.2 2 23 756 779 755 779 0.85

14 20 0.0002 0.021 15.8 1.1 2 23 795 817 794 817 0.96

15 20 0.045 4.9 8.4 1.0 1 23 826 849 826 849 0.93

16 20 0.0011 0.12 13.5 0.4 2 23 1033 1055 1032 1055 0.95

17 20 0.079 8.7 7.6 0.3 1 23 1067 1090 1067 1090 0.96

18 20 1.8 2e+02 3.3 0.3 2 23 1103 1124 1102 1124 0.94

19 20 0.18 20 6.4 0.1 2 23 1133 1155 1132 1155 0.94

20 20 0.0096 1.1 10.5 2.5 1 23 1162 1185 1162 1185 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	9e-06	0.00099	20.0	1.5	1	23	76	98	76	98	0.98
2	20	0.51	56	5.0	3.9	1	23	104	126	104	126	0.97
3	20	1.1e-06	0.00012	22.9	4.3	1	23	132	154	132	154	0.99
4	20	7.1e-05	0.0078	17.2	0.3	1	23	160	182	160	182	0.99
5	20	0.00044	0.048	14.7	0.6	1	23	336	359	336	359	0.95
6	20	0.14	15	6.8	0.1	2	23	370	392	369	392	0.88
7	20	0.22	24	6.2	0.1	3	23	455	475	454	475	0.97
8	20	0.059	6.5	8.0	0.7	1	23	486	508	486	508	0.96
9	20	0.015	1.7	9.8	0.3	1	23	517	540	517	540	0.92
10	20	4	4.4e+02	2.2	0.2	1	23	545	568	545	568	0.91
11	20	0.11	12	7.2	2.0	2	23	642	663	642	663	0.96
12	20	0.011	1.2	10.3	0.2	1	23	668	691	668	692	0.94
13	20	0.85	94	4.3	0.2	2	23	756	779	755	779	0.85
14	20	0.0002	0.021	15.8	1.1	2	23	795	817	794	817	0.96
15	20	0.045	4.9	8.4	1.0	1	23	826	849	826	849	0.93
16	20	0.0011	0.12	13.5	0.4	2	23	1033	1055	1032	1055	0.95
17	20	0.079	8.7	7.6	0.3	1	23	1067	1090	1067	1090	0.96
18	20	1.8	2e+02	3.3	0.3	2	23	1103	1124	1102	1124	0.94
19	20	0.18	20	6.4	0.1	2	23	1133	1155	1132	1155	0.94
20	20	0.0096	1.1	10.5	2.5	1	23	1162	1185	1162	1185	0.97

Sequence Information

Coding Sequence: ATGCATCAAGATGCATTGCAAAAGCAAAAGGTTTATGGACCAAATACTAAAGCTTTGGGGACCGGAAGTTCATCGTGGCAGAGCGAAGATGGTGGTCCAAACTCACGACGCGGTGGTGAGACGCCCTCTTCTTGCGCAACACCAACGTCAGCCAGCTTCCCGTCGGAGCCTGAGGTGGATGCTGACGTCGGCGTTAATGCCGACGGAACCAACGCTATCGCACCTTATCCTTGTCAATTCTGCGACCGAACGTTTCCGCGACTTAGCTACCTGAAAAAACACGAACAGAGTCACGGAGATCAAATGCCATATAGATGCAGTTGGTGTGCCAGATTATTCAAACATAAACGCAGTAGAGATCGACACGTGAAGCTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGAAGCTGCTTTCTCCAGAAGtGACCACTTGAAGATTCATATGAAGACCCATGACACTCAAAAGCCGTATCAGTGCACAACCTGTTCCAGAGGCTACAACACAGCAGCTGCCCTAACATCCCACATACAATCTCACAAGAAACATCATCAATCTCAAACATCCAAACTTCAGGACATTGACTACGGTAGAAGAAGTGTATCCTCTCACAGTACATCATCGCCGCCAATACCAAGCTCTCCATCGCCATCTTTAAACATAGTCTTGAATTCAAAAACTTGTATGAAAAGTACTCAAGGAAGTACTTCGACAACTCCGATTCTGAGCTCTCCACTGAAGTTAGCTTGCATGTATTGTACCAGAGATACCTTCAGTTGTATGCAACAACTCCAGATGCACGTGCATACGATGCACCAAGCTATCTTAAGTGGAGAAACTGTTGCAGCATCTCCATCAACTAATAGAATCAATGAACAAATAAGTTATCAACATGAAACGACTTTCGACAGAAAGCCAGAAGGATCATCTAAAGAACACAAAAGGAAATATCAAGATGATTCAGAAAAATCTATAGAGAAAGATCACTATGAAAACGCATTTACATGCAGTCAATGTACTATGAAATTCTCTACGTTAGGCTCATTAAGGGATCATTTGGTTTCAATTCATAGAACCGATGGTTTTGACTCTGCTTTGATGATGTGTCCTCTTTGTGGCATTCCTTGTACTTCTGCAGCGACTTATGCAGAACACTATGTTCTCCAACATTGTGAAAATCGAAGAACAGATCTCCTAGAAATTAGAGACTATACAGATTCTAAGATGAATGGAAATTATGACACTAAAAGTATCAGGAGTCAGAAATATAGGGAGCAAACGTCTTCTGAGCCAGCTGATTTGACCAATAAGCATTCTACTGGTACAGAAAGTAATTATACAGCTGGTACATTGTTATGTGGACAGTGTGGAGCTGCTTTAAAGGACTTCGAATCATTCAGGGAACACTTAGCTAGACATCTTCAAGCTGATCATAGAAATGATGTTAGACATCCTTGTTTAAAGTGTGAAGCCACTTTTCAAGATAGGGAAGACATGTTGGTACATTTAACGAAACATTATTTGAGCCAGATTAGTAAAGAATATGCTTGTGGTGCATGTAAGAAGCTTTATCCTCATCCTGATCTTCTTCAGAGGCATTTACTCGACAGTCATGCTCATCATCTCTATCGATGCGCCTTGTGCAGAGATACATTTGATTCTAGAGTGGCAATACAGGTTCATTTTGCTGTGAAACACAGTCAAGAATGCAGAATCTATAGATGCAATGCTTGCACAGTGtctaataatgaaaattcaccGGGAAATGCGccagaagaaggaaaaagtttcttccgAAGTGAGTCTGAAATGGCAAACCATGTAAAAAATGTCCACGCACCTCCAACGATGTCAAATAATAGTCCTGTAGCTAGGAGTCCTGCTTCCACTCCAGGAATAACTGGGAATTCCGGACCAAGATGCGTCTTTTGTGGAATCTGTTGTAGTTCCGAGCTGGAACTACAACTCCATTTGGCTAGCCATTCTGCTAACTTATATAGATGTCCTGTTTGTAGAGAAGGATTTgccgtggaatttttattagatagaCATATTACTCAAGCACATCATTCTAGTGACCATCAGGATGTCGTGAGAAGTAATTCTAGAGAGAATGGAAGAATTGGTAGACTACCAAGATTACAGGAAGAGgCTAAATCCCAAAAAAGAGGTCGCTCTCCAGCCTCCAGCAACAACAACTCTTTGAATCAACGTGACAACAACAATAAACGTCCAAATTATACCAATGCATCCTCTCAACAATGCGATCTCTGCGAAAgaggaaaattttccaacgaagcAGAACTTCAAGCTCACAAAAAATTGGTTCACACTCCGATCAAGTTTCAAAATAAGTCTATATCGAGTCTTAGCATGACTTGTGCATATTGTGGAGAAGTATGCCGTTCTAGAACTGACTTAGAATCTCATACAAGAATCCAACATGCATCAAGTGAACCTGGAGGACGCCACAAGTGTAATATTTGTGACGAAGTGTGCCCATCAGGAGCAACACTTGCAGAACATAAACTTCAGAAACATTGTAAGATTCAATTATGTGACACATGTATCGTTTGTCGAGGAAACCTATTTTCAGAATCACAGTTTCTAGAACATGTGCAAAGACACAGTCTGGAGAATGTGGATCCTCAGCAGAGATTAGATGGTTCTCTTCCTCATCTTCCTGCAGCTTGTGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAATGTCGTCTCCATGCCAGACATCACTTAAGAACTTCTGGCTCTCATAGTGTGGCATCCAGTCCCAGTCCCAACCAAAAGAATCAGAGTCCAAGTTGTTGTCTttgtttaagaaattattcagCTGATGACTTTGTTAATTTACCTCCAAGTCGTATAAGTGGAGGAGGACAGTCTTTAAGGGTTTGCAAATCTTGTTACATTCGACACTCTCAGGGTTTACCTATTTTGAATTCATCTTACGAGCCTATTAAATGTGATGACTCTTGGACATCCAGTAATAAAAATGGACAATGGGATAAATCAAAGGATAAATGGGAAACCGAGaataaagaagataaaaacGAGGGGAATGATAGTAAGAAGTGTCAAGATTGTGGGGTGAAATTTGAGAATTCTGACAAGGTGGAGAAACATAGGATAGTCGAGCATGAAAAAGTTATAAGTGGAGTTATGTTGAACACATACACATGTATACAGTGTCAGatgTCGTTCCCAACAGAGGCAAAAATTCAGCAACATGTAAGAAAAGAACATCTAGAAACATCGGGAAGAACTTCCATAGAAACATTACGATGTCATCTGTGTCTTTTTGAAGCTAGCAGTCCATTAGAATTGCAAAGCCATTTGATAGAGCATACTTTCGCAGGATGTGCCGCTCTCAGCTGTTACATTTGCCAATCTCTCTTCACCGCACCTACTGGTCTTCAGAATCATATGCTTCAAGAACACGGTCTGGGTGCTCGTCCCTATGATTGTTCCGAATGTACGCTCAAATTCTTCTTCAGAGCAGAACTAGATCATCATATGTTAACATTTCACCGATCAGGAGACGTGCCATCACCCAGTAAAAATACACAGAATAccactgaaataaaaaaaaaagatgccgaaaaaagaaattgcgaTGAAGGAGTGActgtgaaagaagaaatggtTCTAGGAGCAgcagcagaagaagaagagatcAACGTGGATGAACAAATAGAACAGGATGGTCAAAACGCAGATCAACAATCAGAAATCGagacgaaattaaaaactgaGCTCGAGGAAGAATTTATTCCCGAAAAAATGGAATCGTGA
Protein Sequence: MHQDALQKQKVYGPNTKALGTGSSSWQSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGTNAIAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTTCSRGYNTAAALTSHIQSHKKHHQSQTSKLQDIDYGRRSVSSHSTSSPPIPSSPSPSLNIVLNSKTCMKSTQGSTSTTPILSSPLKLACMYCTRDTFSCMQQLQMHVHTMHQAILSGETVAASPSTNRINEQISYQHETTFDRKPEGSSKEHKRKYQDDSEKSIEKDHYENAFTCSQCTMKFSTLGSLRDHLVSIHRTDGFDSALMMCPLCGIPCTSAATYAEHYVLQHCENRRTDLLEIRDYTDSKMNGNYDTKSIRSQKYREQTSSEPADLTNKHSTGTESNYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDVRHPCLKCEATFQDREDMLVHLTKHYLSQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSPGNAPEEGKSFFRSESEMANHVKNVHAPPTMSNNSPVARSPASTPGITGNSGPRCVFCGICCSSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHITQAHHSSDHQDVVRSNSRENGRIGRLPRLQEEAKSQKRGRSPASSNNNSLNQRDNNNKRPNYTNASSQQCDLCERGKFSNEAELQAHKKLVHTPIKFQNKSISSLSMTCAYCGEVCRSRTDLESHTRIQHASSEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLCDTCIVCRGNLFSESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRTSGSHSVASSPSPNQKNQSPSCCLCLRNYSADDFVNLPPSRISGGGQSLRVCKSCYIRHSQGLPILNSSYEPIKCDDSWTSSNKNGQWDKSKDKWETENKEDKNEGNDSKKCQDCGVKFENSDKVEKHRIVEHEKVISGVMLNTYTCIQCQMSFPTEAKIQQHVRKEHLETSGRTSIETLRCHLCLFEASSPLELQSHLIEHTFAGCAALSCYICQSLFTAPTGLQNHMLQEHGLGARPYDCSECTLKFFFRAELDHHMLTFHRSGDVPSPSKNTQNTTEIKKKDAEKRNCDEGVTVKEEMVLGAAAEEEEINVDEQIEQDGQNADQQSEIETKLKTELEEEFIPEKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_01420489;
80% Identity: -