Basic Information

Insect: Andrena marginata
Gene Symbol: znf423
Assembly: GCA_963932335.1
Location: OZ010663.1:3493356-3509762[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 1e-05 0.00082 20.0 1.5 1 23 92 114 92 114 0.98

2 20 0.57 47 5.0 3.9 1 23 120 142 120 142 0.97

3 20 1.2e-06 0.0001 22.8 4.3 1 23 148 170 148 170 0.99

4 20 0.00027 0.022 15.5 0.2 1 23 176 198 176 198 0.99

5 20 0.00033 0.027 15.2 0.6 1 23 354 377 354 377 0.95

6 20 0.5 41 5.2 0.0 2 23 388 410 387 410 0.88

7 20 0.25 20 6.2 0.1 3 23 474 494 473 494 0.97

8 20 0.0078 0.64 10.9 0.2 1 23 506 528 506 528 0.97

9 20 0.017 1.4 9.8 0.3 1 23 537 560 537 560 0.92

10 20 4.5 3.7e+02 2.2 0.2 1 23 565 588 565 588 0.91

11 20 0.44 36 5.4 2.0 2 23 662 683 662 683 0.96

12 20 0.0062 0.51 11.2 0.1 1 23 688 711 688 712 0.94

13 20 4 3.3e+02 2.4 0.1 2 23 771 794 770 794 0.81

14 20 0.00024 0.02 15.6 1.0 2 23 810 832 809 832 0.96

15 20 1.3 1.1e+02 3.9 0.6 1 12 841 852 841 864 0.76

16 20 0.0051 0.42 11.4 0.5 2 23 1054 1076 1053 1076 0.95

17 20 0.088 7.3 7.6 0.3 1 23 1086 1109 1086 1109 0.96

18 20 1.5 1.2e+02 3.7 0.4 2 23 1122 1143 1121 1143 0.94

19 20 0.57 47 5.0 0.1 2 23 1152 1174 1151 1174 0.93

20 20 0.13 10 7.1 3.0 1 23 1181 1204 1181 1204 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	1e-05	0.00082	20.0	1.5	1	23	92	114	92	114	0.98
2	20	0.57	47	5.0	3.9	1	23	120	142	120	142	0.97
3	20	1.2e-06	0.0001	22.8	4.3	1	23	148	170	148	170	0.99
4	20	0.00027	0.022	15.5	0.2	1	23	176	198	176	198	0.99
5	20	0.00033	0.027	15.2	0.6	1	23	354	377	354	377	0.95
6	20	0.5	41	5.2	0.0	2	23	388	410	387	410	0.88
7	20	0.25	20	6.2	0.1	3	23	474	494	473	494	0.97
8	20	0.0078	0.64	10.9	0.2	1	23	506	528	506	528	0.97
9	20	0.017	1.4	9.8	0.3	1	23	537	560	537	560	0.92
10	20	4.5	3.7e+02	2.2	0.2	1	23	565	588	565	588	0.91
11	20	0.44	36	5.4	2.0	2	23	662	683	662	683	0.96
12	20	0.0062	0.51	11.2	0.1	1	23	688	711	688	712	0.94
13	20	4	3.3e+02	2.4	0.1	2	23	771	794	770	794	0.81
14	20	0.00024	0.02	15.6	1.0	2	23	810	832	809	832	0.96
15	20	1.3	1.1e+02	3.9	0.6	1	12	841	852	841	864	0.76
16	20	0.0051	0.42	11.4	0.5	2	23	1054	1076	1053	1076	0.95
17	20	0.088	7.3	7.6	0.3	1	23	1086	1109	1086	1109	0.96
18	20	1.5	1.2e+02	3.7	0.4	2	23	1122	1143	1121	1143	0.94
19	20	0.57	47	5.0	0.1	2	23	1152	1174	1151	1174	0.93
20	20	0.13	10	7.1	3.0	1	23	1181	1204	1181	1204	0.97

Sequence Information

Coding Sequence: ATGTTGTTCAAGGGGAACAGCTCGAGGCTGGAGTTGTTGATAGGGAAGATCCAGGCTCATAAGGAACCCACTCAGGATGAGCACCATAAGTCTAAAGAGGCCTTGGGGACCGGAAGCTCGTCCTGGCACAGCGAGGATGGCGGGCCGAACTCGCGCCGCGGGGGCGAGACGCCCTCGTCCTGCGCGACGCCGACGTCGGCCAGCTTCCCGTCGGAGCCTGAAGTGGATGCCGACGTCGGCCTCAACGCCGACGGGAACAACCCTGCCGCGCCTTATCCTTGCCAGTTCTGCGACCGCACGTTCCCGCGGTTGAGCTACCTGAAGAAGCACGAACAGAGTCACGGCGATCAGATGCCGTATCGATGCAGCTGGTGCGCGAGACTGTTCAAACATAAGCGCAGCAGAGATCGACACGTGAAGCTTCACACCGGAGATCGAAGATACCGATGCACGCACTGCGAGGCTGCTTTCTCTCGGAGCGACCACCTGAAGATCCACATGAAGACCCACGACACCCAGAAGCCCTACCAGTGCACAGCCTGCTCCAGGGGCTACAACACGGCCGCGGCGTTGACCTCCCACATGCAGTCGCACAAGAAGCTCCACCAGTCGCAGGTCGCCAGCAAGCTGCAGGACGTGGAGTACGGTCGACGCAGCGTATCCTCGCACAGCACATCATCGCCCCCCGTCGCGAGCTCCCCGTCGCCATCGCTGAACCTGTCCCTCGCCCCGAAGTCCGGGGTGAAGGGTTCGCAGGGCAGCGCCTCGACCACGCCGATCCTGAGCTCGCCCCTCAAGCTGGCTTGCATGTACTGCACCAGGGACTCGTTCAGCTGCATGCAGCAGCTGCAGGTGCACGTGCACACGATGCACCAGGCGATACTGAGCGGCGAGAGCGTGGCCGTGCCGCCCTCGCCTAGCAGGAGCAGCGAGCAGCTCGCCTACCAGCGCGACAAAGGGGGGCTGGACCGGGCCGAGGGTGGTGCGAAGGACCATCGCGAGAGGAAGTACCAGGAGGAGTCGGAGAGACGAACGGAGAAGGAGCACTACGAGAACTCGTTCACCTGCAACCAGTGCACCATGAAGTTCTCCACGCTGGGTTCCCTGCGGGACCACCTGGTCTCCATCCACAGGACAGACGGCTTCGGCTCCGCGCTGATGATGTGCCCCCTATGCGGCATCCCGTGCGCCTCCGCGGCAGCCTACGCCGAGCACTACGTTCTCCAGCACTGCGAGAACAGGCGGATGGGCGGCCTGGATGGTCGCGAGTACGTGGACGCGAAGATGAACGGCAGCTACGGGGACGCGAAGAGCTCCAGGGCGGAGAAGCCTGCGGATCCGTCGCTCTCCGAGCCGGCCGACCTCACCAGCAAGCATTCCAGGTCGACGGAGGGCAGCTACACCGCGGGCACCCTGCTCTGCGGCCAATGCGGCGCCGCTCTCAAGGACTTCGAGTCCTTCAGGGAGCACTTGGCCAGGCATTTGCAAGCCGACCACCGCAACGACGCCATGAGGCATCCCTGCCCGAAGTGCGAGGCTGCCTTCCAGGACAGGGAGGACATGCTTGCGCACCTGACCAAGCACTATCTGGGTCAGATCAGCAAGGAGTACGCTTGCGGGGCCTGCAAGAAGCTCTACCCTCACCCTGACCTTCTACAGAGACACCTGCTCGATAGCCACGCTCATCATCTCTATAGATGCGCCCTGTGCAGGGACACGTTCGACTCCAGGGTGGCGATACAGGTGCACTTCGCTGTGAAGCACAGCCAGGAGTGCAGGATCTATCGCTGCAACGCCTGCACTGCTCCTAATAATGAGAACTCGCCTGGGAACGCGCCAGGGGAAGGCAGAAGCTTCTTCAGGAGCGAGTCGGAGATGGCTAGCCACGTGAGGAGCGTCCACGCCCCGCCCGCCGTGTCGAACAGCAGTCCTGTGGCCAGGAGTCCTGCGTCCACTCCTGGTGTAACCGCTGGCTCAGGGCCTAGGTGCGTCTTCTGCGGCGTCTGCTGCAACTCGGAGCTGGAGCTGCAGCTTCACCTCGCCAGCCACTCGAGCAACCTGTACAGGTGCCCCATCTGCAGGGAGGGCTTCGCCGTTGAGTTCCTGCTCGACAGGCATATCGCACAGGCGCACCACTCCAGCGAACATCAGGCCAGGGAGAACGGGCGGAACGGAAGGCCCGCGCCGAGGTCCCAAGAAGAGCCAAAGTCCCAGAAAAGGGGCCGCTCCCCAGCGTCCAGCAACAACAACTCCCTGAATCAGCGTGACAACAACAACAAGCGAGCGAACTACACCAGCACGGGTGCCCAGCAGTGCGAGCTCTGCGAGAGGGGCGAGTTCGCGAACGAGGCGGAGCTCCAGGCCCACAAGAAGCTAGCCCACGCGCCTGCCAAGCCTCAGAGCAAGTCTCTGTCCAGTTTAAGCATGACCTGCGCCTACTGCGGCGAGGTGTGCCGCTCCAGAACCGAGCTGGAGTCCCACACGAGGATCCAGCACGCCTCGAACGAGCCCGGTGGACGGCACAAGTGCAACATCTGCGACGAGGTCTGCCCGTCCGGAGCTATCCTAGCCGAGCACAAGCTGCAGAAGCACTGCAAGATCCAGCTGAGCGACACCTGCATCGTGTGCCGCGGGAGCCTGGCCACGGAGTCCCAGTTCCTCGAGCACGTGCAGAGACACAGCCTGGAGAACGTGGACCCTCAGCAGAGGCTAGACGGCTCGCTCCCTCACCTGCCGGCCGCGTGTGTCGTCTGCAGGCAGACCTTGATCAGCGACCTGGAGTGTCGCCTCCACGCCAGACACCACCTCAGAGCCTCGACTGGGTCCAGGAGCGCTGGCTCCAGCCCCAGCCCGAACCAGAAGAGCCACAACCCGGGCTGCTGCCTCTGCCTCAGGGACTACTCCGTCGACGACTTCGTCAGCCTACCTCCCAATCACATCAGCGGCGGTGGACAGTCCCTCAGGGTCTGCAAGTCCTGCTACATCCGCCACTCTCAGGGCCTGCCTATCCTGAACTCGCCCTACGAGCACGCCAGGACTAAATGCGACAGGGGCTGGATATCCAGCAAGGACCCTCAGTGGGACGGGTCCAGGGACAAGTGGGACTCCGAGCGGGCGTTTAAGGCGGAGGACAGGGGCAGCGAGGGGAACGACGGCAAGAGGTGTCAGGATTGCGGGGTGAAGTTCGAGGACCCTGAGGAAGCGGAGAAACACAGGCACATGGAGCACGAGAAGGCTGGGTCTGGCTCGAACACGTACACGTGTATACAGTGTCAGATGTCGTTCCCAACGGAAGCTAAGATACAGCAGCACGTGAGAAAGGAGCATCTGGAGTCGTCGGGGAAAGCATCCGTCGAGGCACTGCGCTGCCACTTGTGCCTCTTCGAAGCTAGCAGTCCGTTGCAATTGCAGAGCCACTTGATAGAGCATACGTTCGCTGGCTGCGCTGCTCTCAGTTGCTACATTTGCCAGTCCCTCTTCACGGCGCCTATTGGACTTCAGaaCCACATGCTGCAGGAACACGGTCTGGGAGCTCGGCCTTACGATTGCTCCAAGTGCACGCTTAAGTTCTTCTTCAGGGCCGAGCTGGACCACCACGTGCTAACGTTCCATCGCTCCGGAGGGGCTCCGTCGCCCGCTGAGAACCCACAGAACTCTGTCGAAGCGAAACCTAGAGAGCCGAAGGAGCAGAACAGTAGCGAGGGTGTGATGGTGAAGGAGGAAGTGTTGCCTGACGCCGCAGACGAGGAAGAGGAGATAAACGTCGACGAGCAAGTGGAGCAGGACGACCGGGAGGCGGACAAACGGGCAGAGTCCGAGCAGGAGATGAAAATCGAGGTCGACGAGGAAGCTGTTCCGGAGAAAACAGAGTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPTQDEHHKSKEALGTGSSSWHSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGLNADGNNPAAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKLHQSQVASKLQDVEYGRRSVSSHSTSSPPVASSPSPSLNLSLAPKSGVKGSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQVHVHTMHQAILSGESVAVPPSPSRSSEQLAYQRDKGGLDRAEGGAKDHRERKYQEESERRTEKEHYENSFTCNQCTMKFSTLGSLRDHLVSIHRTDGFGSALMMCPLCGIPCASAAAYAEHYVLQHCENRRMGGLDGREYVDAKMNGSYGDAKSSRAEKPADPSLSEPADLTSKHSRSTEGSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDAMRHPCPKCEAAFQDREDMLAHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTAPNNENSPGNAPGEGRSFFRSESEMASHVRSVHAPPAVSNSSPVARSPASTPGVTAGSGPRCVFCGVCCNSELELQLHLASHSSNLYRCPICREGFAVEFLLDRHIAQAHHSSEHQARENGRNGRPAPRSQEEPKSQKRGRSPASSNNNSLNQRDNNNKRANYTSTGAQQCELCERGEFANEAELQAHKKLAHAPAKPQSKSLSSLSMTCAYCGEVCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGAILAEHKLQKHCKIQLSDTCIVCRGSLATESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGSRSAGSSPSPNQKSHNPGCCLCLRDYSVDDFVSLPPNHISGGGQSLRVCKSCYIRHSQGLPILNSPYEHARTKCDRGWISSKDPQWDGSRDKWDSERAFKAEDRGSEGNDGKRCQDCGVKFEDPEEAEKHRHMEHEKAGSGSNTYTCIQCQMSFPTEAKIQQHVRKEHLESSGKASVEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCTLKFFFRAELDHHVLTFHRSGGAPSPAENPQNSVEAKPREPKEQNSSEGVMVKEEVLPDAADEEEEINVDEQVEQDDREADKRAESEQEMKIEVDEEAVPEKTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00088289; iTF_00084784; iTF_00086611; iTF_00089064; iTF_00085661;
80% Identity: -