Basic Information

Insect: Nomada hirtipes
Gene Symbol: znf423
Assembly: GCA_951802735.1
Location: OX637931.1:10577268-10592777[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 8.7e-06 0.0009 20.0 1.5 1 23 92 114 92 114 0.98

2 20 0.49 51 5.0 3.9 1 23 120 142 120 142 0.97

3 20 1.1e-06 0.00011 22.8 4.3 1 23 148 170 148 170 0.99

4 20 0.00023 0.024 15.5 0.2 1 23 176 198 176 198 0.99

5 20 0.00028 0.029 15.2 0.6 1 23 352 375 352 375 0.95

6 20 0.44 45 5.2 0.0 2 23 386 408 385 408 0.88

7 20 0.21 22 6.2 0.1 3 23 471 491 470 491 0.97

8 20 0.016 1.7 9.7 2.3 1 23 503 525 503 525 0.96

9 20 0.011 1.2 10.2 0.2 1 23 534 557 534 557 0.93

10 20 3.9 4e+02 2.2 0.2 1 23 562 585 562 585 0.91

11 20 0.52 53 4.9 0.3 2 23 659 680 659 680 0.96

12 20 0.0097 1 10.4 0.1 1 23 685 708 685 709 0.94

13 20 1.4 1.5e+02 3.6 0.4 3 23 773 795 772 795 0.82

14 20 0.00021 0.022 15.6 1.0 2 23 811 833 810 833 0.96

15 20 1.1 1.2e+02 3.9 0.6 1 12 842 853 842 865 0.76

16 20 0.00085 0.088 13.7 0.1 2 23 1055 1077 1055 1077 0.97

17 20 0.098 10 7.2 1.1 1 23 1087 1110 1087 1110 0.96

18 20 1.3 1.3e+02 3.7 0.4 2 23 1123 1144 1122 1144 0.94

19 20 0.49 51 5.0 0.1 2 23 1153 1175 1152 1175 0.93

20 20 0.02 2 9.4 3.5 1 23 1182 1205 1182 1205 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	8.7e-06	0.0009	20.0	1.5	1	23	92	114	92	114	0.98
2	20	0.49	51	5.0	3.9	1	23	120	142	120	142	0.97
3	20	1.1e-06	0.00011	22.8	4.3	1	23	148	170	148	170	0.99
4	20	0.00023	0.024	15.5	0.2	1	23	176	198	176	198	0.99
5	20	0.00028	0.029	15.2	0.6	1	23	352	375	352	375	0.95
6	20	0.44	45	5.2	0.0	2	23	386	408	385	408	0.88
7	20	0.21	22	6.2	0.1	3	23	471	491	470	491	0.97
8	20	0.016	1.7	9.7	2.3	1	23	503	525	503	525	0.96
9	20	0.011	1.2	10.2	0.2	1	23	534	557	534	557	0.93
10	20	3.9	4e+02	2.2	0.2	1	23	562	585	562	585	0.91
11	20	0.52	53	4.9	0.3	2	23	659	680	659	680	0.96
12	20	0.0097	1	10.4	0.1	1	23	685	708	685	709	0.94
13	20	1.4	1.5e+02	3.6	0.4	3	23	773	795	772	795	0.82
14	20	0.00021	0.022	15.6	1.0	2	23	811	833	810	833	0.96
15	20	1.1	1.2e+02	3.9	0.6	1	12	842	853	842	865	0.76
16	20	0.00085	0.088	13.7	0.1	2	23	1055	1077	1055	1077	0.97
17	20	0.098	10	7.2	1.1	1	23	1087	1110	1087	1110	0.96
18	20	1.3	1.3e+02	3.7	0.4	2	23	1123	1144	1122	1144	0.94
19	20	0.49	51	5.0	0.1	2	23	1153	1175	1152	1175	0.93
20	20	0.02	2	9.4	3.5	1	23	1182	1205	1182	1205	0.97

Sequence Information

Coding Sequence: ATGTTATTTAAGGGGAACAGCTCGACGCTGGAGCTACTGATAGGGAAAATCCAGGCCCATAAAGAACCCTCTCAGGAGGAGCAGCACAAGTCCAAAGAGGCATTGGGGACCGGAAGTTCGTCGTGGCAGAGCGAGGATGGCGGACCGAACTCGCGACGAGGAGGCGAGACGCCTTCGTCTTGCGCGACGCCGACGTCGGCTAGTTTTCCGTCGGAGCCCGAGGTCGACGCCGACGTTGGCGTGAACGCCGACGGAAATAATGCCACGGCACCCTATCCTTGCCAATTTTGCGACCGCACATTTCCACGGCTGAGCTACCTGAAGAAACACGAACAGAGCCACGGCGATCAAATGCCATATCGATGCAGCTGGTGCGCGAGATTATTCAAGCACAAACGTAGCAGAGATCGTCACGTGAAGCTTCACACAGGAGACCGACGATATCGATGCACGCACTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTGAAGATCCACATGAAGACCCACGACACCCAAAAGCCGTACCAATGCACAGCGTGCTCCAGGGGTTACAACACAGCAGCTGCCCTAACGTCCCACATGCAGTCCCATAAGAAACACCATCAATCTCAGGGCACCGCCAAACTCCAAGATATCGACTACGGCCGTAGAAGCGTCTCGTCTCACAGTACATCGTCCCCGCCGGTACCAAGCTCTCCGTCCCCGTCCCTGAACCTTTCATTGAACCCGAAAGTCAGCCTGAAAAGCTCGCAGGGCAGTGCGTCCACCACACCCATCCTAAGCTCCCCGTTAAAATTAGCCTGCATGTACTGCACCAGGGACTCGTTCAGCTGCATGCAGCAACTGCAAATGCACGTGCACGCCATGCACCAAACAATCCTGAGCGGGGAGAGCGCCGCGATATCACCGTCGCCGGGTAGAACCAACGAGCAGTCCGGTTATAAACGCGAGAAGAACTTGGATCATCCGGAAGGATCGTCCAAGGGGCACGATAGAAAATATCCCGAGGACCCGGATCGATCCGGGGACAAAGATCCCTATGAGAACGCCTTCACGTGCAACCAGTGCACCATGAAATTCTCTACACTGGGATCCTTGAGGGATCACCTGGTTTCCATTCATAGAATAGACAATTTTGGGTCCAGTCTCATGATGTGCCCCCTCTGCGGTATACCATGTGCCTCGGCGGCTGCGTACGCCGAGCACTACGTTCTTCAGCACTGCGAGAACAGAGGTATCGGTCCCCTGGACGGCGGAGAGTACGCGGAGGCCAAAGTGAACGGCAGCTACGATTCTAAGGTGTCGAGGGGTCAACTGTCCAGAGATCAGACACCGTCGGAGCCAGCAGACTTGACGAGCAAACATTCCACGTCCACGGGGAACAGTTACACAGCGGGCACGCTGTTGTGCGGCCAATGCGGGGCAGCCTTGAAGGACTTCGAGTCCTTCAGGGAGCATCTGGCCAGGCATCTGCAGGCCAACCACAGGAACGACGTGGTCAGACACTGTTGCCCTAAATGCGAGGCCAGCTTCCAAGACAGGGAGGACATGCTGGCTCATTTGACGAAGCATTATCTCGGGCAAATCAGCAAGGAGTACGCCTGCGGCGCGTGCAAGAAACTCTATCCCCATCCTGATCTACTCCAGAGGCATTTGCTCGAGAGTCACGCTCACCACCTTTACAGGTGCGCCCTGTGCAGAGACACCTTCGATTCCAGAGTGGCTATACAGGTCCACTTCGCCGTGAAGCACAGCCAGGAGTGCAGGGTGTACAGGTGCAACGTTTGCACGCTGTCCAACAACGAGAACTCGCCTGGCAATTCCCCGGGCGAGGGCAAGAGCTTCTTCAGAAGTGAGAGCGAAATGGCGAGTCACGTTAGGAACGTCCACGCGCCGCCGAGTGTTTCGAACACCAGTCCGGTGGCTAGAAGCCCTGCTTCCACCCCCGGTATCACCGGCAAGCCTGGGCCCAGATGCGTCTTCTGCGGCGTTTCCTGCGGCTCTGAGTTGGAGCTGCAGTTGCACTTGGCCAGCCATTCGGCTAATCTGTACAGGTGTCCAGTTTGCAGGGAGGGATTCGCCGTGGAGTTTCTGTTGGACAGGCATATCGCTCAGGCTCATCACTCTGGAGATCATCAGAGCGGCGTCAGAAGTAGTTCCAGAGAGAATGGGAGAATCGGGAGGCCGCCTAGATCGCAGGAAGAGCCCAAGTCCCAGAAGAGGGGCCGTTCTCCGGCGTCCAGCAACAACAATTCCCTCAACCAACGCGACAACAACAAACGTCCCAATTATACCAACACCTCCGCGCAGCACTGCGATCTCTGCGAGAGGGCCGATTTCGCCACCGAGTCGGAGCTTCAGGCCCACAAGAAGCTGGCCCACACGCCGCCGAAGCTTCAAGCCAAGTCTCTGTCCAGCGTCAGCATGACCTGCGCGTACTGCGGGGAAGTCTGTCGGTCCAGGACCGAACTGGAGTCCCACACAAGGATCCAGCACGCGTCGAACGAACCCGGCGGACGTCACAAGTGCAACATCTGCGACGAGGTGTGCCCATCGGGCGCCATTCTGGCGGAGCACAAGCTCCAGAAGCACTGCAAGATCCAGTTAAGCGACACCTGCATAGTCTGTCGCGGGAGCTTGGGTTCGGAGTCGCAGTTCCTCGAACACGTTCAGAGACACAGCCTGGAGAACGTGGACCCCCAGCAAAGATTGGACGGCTCCCTGCCGCATCTTCCAGCGGCCTGCGTGGTCTGTAGACAGACGTTGATCAGCGACCTGGAGTGCCGTCTACACGCTAGACATCATCTTAGAGCCCCCTCGGGGTCGCACAGTGTTGGATCGAGCCCTAGCCCGAAGCAGAAGAGCCAGAGTCCAAGCTGCTGCCTCTGTTTGAGGGACTATTCGTCCGAGGACTTCGTCAGTCTTCCGCCGAGTCACGTAGCTGGCGGTGGACAGTCCTTGAGGGTCTGCAAGAGCTGTTACGTCAGGCATTCGCAGGGACTGCCGATTCTGAGCACGCAGTACGAGCCTGTCAGGAGTAAATGTGATGGACCTTGGTCGTCCACGCAGAAGGATGGACAGTGGGACGGGCTGGTGGATAAATGGGACGAGGAGAATAGATTCAAAGAGGGCAGGGTGAACGAAGGTGTCGACGGGAGGAGGTGCGATGGTTGCGGGGTGAAGTTTGAGGACGCCGAGGAGGTGGAGAAGCATAGGATGACGGGACACGAGAAGAGCGGGGCTGGGATGAACACGTACACCTGTATACAGTGTCAGATGTCCTTCCCGACGGAGGCGAAGATACAACATCACGTGAGAAAAGAACACCTGGAGGCGTCGGGAAAGGCTTCCATAGAGGCACTGAGGTGTCATCTTTGCCTTTTTGAAGCCAGCAGCCCGTTGCAATTGCAGAGTCATTTGATAGAGCACACTTTTGCTGGCTGCGCAGCCCTGAGCTGCTACATTTGCCAATCCCTCTTCACTGCACCTATTGGCCTTCAGaaTCACATGCTACAGGAGCACGGCCTAGGCGCTCGTCCTTACGACTGTTCCAAGTGCACGCTCAAGTTCTTCTTCAGGGCAGAGTTAGACCACCACATGCTAACATTCCATCGTCCAGGAGAATTATCTCCGCACAGTGAGAACGCGCAAACCGTGAACGAGCAGAAGGCGAAGGATTCAGAGGAAAGGAACTGCGACGACGGTGTAACGGTTAAGGAAGAAATCGTTCCAGAAGTTGCAGACGAAGAGGAGGAGATCAATGTGGACGAACAAGCGGAACTGGAAGATCGAGACGGTGACAAACAGTCAGAGGGAAATGcagggaaaaaattgaaaactgaAATCGAAGGAGAAATTGTTCCTGAGAAAATGGAATCCTGA
Protein Sequence: MLFKGNSSTLELLIGKIQAHKEPSQEEQHKSKEALGTGSSSWQSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGNNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSQGTAKLQDIDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPKVSLKSSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHAMHQTILSGESAAISPSPGRTNEQSGYKREKNLDHPEGSSKGHDRKYPEDPDRSGDKDPYENAFTCNQCTMKFSTLGSLRDHLVSIHRIDNFGSSLMMCPLCGIPCASAAAYAEHYVLQHCENRGIGPLDGGEYAEAKVNGSYDSKVSRGQLSRDQTPSEPADLTSKHSTSTGNSYTAGTLLCGQCGAALKDFESFREHLARHLQANHRNDVVRHCCPKCEASFQDREDMLAHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLESHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRVYRCNVCTLSNNENSPGNSPGEGKSFFRSESEMASHVRNVHAPPSVSNTSPVARSPASTPGITGKPGPRCVFCGVSCGSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHIAQAHHSGDHQSGVRSSSRENGRIGRPPRSQEEPKSQKRGRSPASSNNNSLNQRDNNKRPNYTNTSAQHCDLCERADFATESELQAHKKLAHTPPKLQAKSLSSVSMTCAYCGEVCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGAILAEHKLQKHCKIQLSDTCIVCRGSLGSESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRAPSGSHSVGSSPSPKQKSQSPSCCLCLRDYSSEDFVSLPPSHVAGGGQSLRVCKSCYVRHSQGLPILSTQYEPVRSKCDGPWSSTQKDGQWDGLVDKWDEENRFKEGRVNEGVDGRRCDGCGVKFEDAEEVEKHRMTGHEKSGAGMNTYTCIQCQMSFPTEAKIQHHVRKEHLEASGKASIEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCTLKFFFRAELDHHMLTFHRPGELSPHSENAQTVNEQKAKDSEERNCDDGVTVKEEIVPEVADEEEEINVDEQAELEDRDGDKQSEGNAGKKLKTEIEGEIVPEKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_01069170;
80% Identity: -