Basic Information

Insect: Apis dorsata
Gene Symbol: znf423
Assembly: GCA_000469605.1
Location: NW:749285-839868[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 6.1e-06 0.00037 19.9 1.5 1 23 145 167 145 167 0.98

2 21 0.35 21 4.9 3.9 1 23 173 195 173 195 0.97

3 21 7.5e-07 4.5e-05 22.8 4.3 1 23 201 223 201 223 0.99

4 21 0.00016 0.0098 15.4 0.2 1 23 229 251 229 251 0.99

5 21 8.9e-05 0.0054 16.2 0.6 1 23 404 427 404 427 0.96

6 21 0.31 19 5.1 0.0 2 23 438 460 437 460 0.88

7 21 0.15 9 6.1 0.1 3 23 524 544 523 544 0.97

8 21 0.0041 0.25 11.0 1.3 1 23 556 578 556 578 0.97

9 21 0.01 0.62 9.7 0.3 1 23 587 610 587 610 0.92

10 21 2.7 1.6e+02 2.1 0.2 1 23 615 638 615 638 0.91

11 21 3.9 2.4e+02 1.6 0.3 10 23 670 684 668 684 0.93

12 21 0.08 4.8 6.9 2.1 2 23 712 733 712 733 0.96

13 21 0.0068 0.41 10.3 0.1 1 23 738 761 738 762 0.94

14 21 0.93 56 3.6 0.2 2 23 826 849 825 849 0.83

15 21 0.00013 0.008 15.7 1.1 2 23 865 887 864 887 0.96

16 21 0.03 1.8 8.3 1.0 1 23 896 919 896 919 0.93

17 21 0.001 0.062 12.9 0.1 2 23 1107 1129 1106 1129 0.95

18 21 0.033 2 8.2 0.4 1 23 1139 1162 1139 1162 0.96

19 21 2 1.2e+02 2.5 0.4 2 23 1175 1196 1174 1196 0.93

20 21 0.35 21 4.9 0.1 2 23 1205 1227 1204 1227 0.93

21 21 0.016 0.99 9.1 3.1 1 23 1234 1257 1234 1257 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	6.1e-06	0.00037	19.9	1.5	1	23	145	167	145	167	0.98
2	21	0.35	21	4.9	3.9	1	23	173	195	173	195	0.97
3	21	7.5e-07	4.5e-05	22.8	4.3	1	23	201	223	201	223	0.99
4	21	0.00016	0.0098	15.4	0.2	1	23	229	251	229	251	0.99
5	21	8.9e-05	0.0054	16.2	0.6	1	23	404	427	404	427	0.96
6	21	0.31	19	5.1	0.0	2	23	438	460	437	460	0.88
7	21	0.15	9	6.1	0.1	3	23	524	544	523	544	0.97
8	21	0.0041	0.25	11.0	1.3	1	23	556	578	556	578	0.97
9	21	0.01	0.62	9.7	0.3	1	23	587	610	587	610	0.92
10	21	2.7	1.6e+02	2.1	0.2	1	23	615	638	615	638	0.91
11	21	3.9	2.4e+02	1.6	0.3	10	23	670	684	668	684	0.93
12	21	0.08	4.8	6.9	2.1	2	23	712	733	712	733	0.96
13	21	0.0068	0.41	10.3	0.1	1	23	738	761	738	762	0.94
14	21	0.93	56	3.6	0.2	2	23	826	849	825	849	0.83
15	21	0.00013	0.008	15.7	1.1	2	23	865	887	864	887	0.96
16	21	0.03	1.8	8.3	1.0	1	23	896	919	896	919	0.93
17	21	0.001	0.062	12.9	0.1	2	23	1107	1129	1106	1129	0.95
18	21	0.033	2	8.2	0.4	1	23	1139	1162	1139	1162	0.96
19	21	2	1.2e+02	2.5	0.4	2	23	1175	1196	1174	1196	0.93
20	21	0.35	21	4.9	0.1	2	23	1205	1227	1204	1227	0.93
21	21	0.016	0.99	9.1	3.1	1	23	1234	1257	1234	1257	0.97

Sequence Information

Coding Sequence: ATGTCTAGAAGGAAGCAGGCAAAACCTCGATCTCTGAAACGAGACGAAGAGTGGGACGACGGGAACGAGCAGAATGTCCTGGAGGTAACCGAGCAGGATAATGAGGCAACGGGAATTAAGCaggacgaggaggaggaggaggaggaagaggagctGCAGAGAGCTTTCAGCCACCACTCGGAGGagTATCTACAAGAGGGGAGGCCATCTTCGGTTCAAGGATTAGATTTGGAGAATCAGAACAGTCTCGACAGCGAGGCGTTGGGGACCGGAAGTTCGTCGTGGCAGAGCGAGGATGGCGGACCAAACTCGCGGCGAGGCGGCGAGACGCCCTCGTCTTGCGCGACCCCGACGTCGGCCAGTTTCCCGTCGGAGCCAGAGGTCGACGCCGACGTCGGAGTGAACGCCGACGGGAGCAACGCGACAGCCCCTTACCCTTGCCAATTCTGCGACCGCACGTTCCCCCGGCTTAGCTATCTCAAGAAGCACGAACAGAGTCACGGGGACCAAATGCCATACAGGTGCAGCTGGTGTGCCAGATTATTCAAACATAAACGCAGCAGAGATCGACACGTAAAGCTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGAGGCTGCTTTCTCCAGGAGCGACCATCTGAAGATCCATATGAAAACTCACGACACGCAGAAACCGTATCAGTGCACGGCCTGTTCCAGAGGGTACAACACAGCAGCTGCCTTGACATCCCATATGCAATCTCACAAGAAACATCATCAATCGCAAGGATCGGCCAAGGACATCGATTACGGTAGAAGAAGCGTGTCCTCTCACAGTACATCATCGCCGCCAGTACCGAGTTCCCCATCACCGTCTTTAAACCTCTCCTTGAACCCGAAATCCGGGTTGAAAAGCTCGCAGGGCAGTGTTTCGACAACGCCGATCCTAAATTCTCCATTGAAGCTTGCTTGTATGTACTGCACCAGAGATTCTTTCAACTGCATGCAACAGCTCCAGATGCACGTGCATACAATGCATCAAGCTATCTTAAGCGGCGAAACTGTTGCGGTATCTCCATCGACCAATAGAGCCAACGAACAGATTGGTTATCAACATGgtgagaaaaatttagatcGATCGGAAGGAACTTCGAAGGAGCATAATAGGAAATATCAAGATGATTCAGAGAGGTCTATGGAAAAGGATCATTATGAAAACGCGTTTACGTGCAATCAGTGTACCATGAAATTCTCCACATTAGGCTCTTTGAGAGATCACTTGATCTCGATCCATAGAACGGACAGTTTCAACTCTGCCTTGATGATGTGCCCTCTTTGCGGCATTCCTTGTGCTTCGGCAGCTGCTTACGCGGAACATTATGTTCTTCAACATtgtgaaaatcgatcgatagcTCCCCTGGAAAGTAAAGACTATATAGATGCGAAAATGAACGGAAGTTACGAGTCTAAAAGTTCCAGAAATCAGAAATCTAGAGAACAAATATCTTCTTCTGAGCCAGCAGATTTAACTAGCAAGCATACCACCACTATGGAAAACAATTATTCAGCTGGTACTCTGTTATGTGGCCAATGTGGAGCAGCTTTAAAAGACTTTGAATCTTTTAGAGAACATCTGGCTAGACACCTTCAAGCTAATCATAGAAACGATGCTGTCAGACATTCTTGTCCCAAGTGTGAGGCCACTTTTCAAGACAGGGAAGATATGTTTGTGCACTTGACAAAGCATTATCTAGGTCAGATTAGTAAAGAGTATGCCTGTGGTGCCTGCAAAAAGCTCTATCCCCATCCAGATCTTCTTCAAAGGCATTTACTCGATAGTCATGCTCACCACCTTTACAGATGCGCTCTGTGCAGAGACACTTTTGATTCCAGAGTGGCGATACAAGTCCATTTTGCTGTGAAACACAGTCAGGAATGTAGGATCTATAGATGCAATGCTTGTACGGTGTCCAATAACGAAAATTCACCAGGTAATGCACcaggagaaggaaaaagtttCTTCAGGAGTGAATCCGAGATGACAAATCATGTGAGAAATGTCCATGCACCTCCTACTGTATCAAATAACAGCCCTGTAGCCAGAAGTCCTGCATCTACCCCTGGAATAACTGGAAATTCCGGACCAAGATGTGTTTTCTGTGGAATTTGTTGTACTTCTGAACTGGAATTACAACTTCATTTGGCTAGCCATTCTGCTAACTTATACAGATGTCCAGTTTGTAGAGAGGGATTTGCTGTAGAATTTTTGTTGGACAGGCATATTGCTCAAGCACATCATTCCAGTAGTCATCAAGGTATTATTAGAAGTAGCTCTAGAGAAAATGGAAGGATTGGTAGACCGCCAAGATTGCAAGAAGAGacaaAATCTCAAAAAAGAGGTCGTTCTCCAGCATCCAGCAACAACAACACCGTAAATCAACGAGACAACAATAATAAACGTCCAAATTACTCCAATACATCTTCTCAACAGTGTGATCTCTGCGAAAGAGGGGAATTTTCTAATGAAACAGAACTCCAAGCCCACAAGAAATTGGTTCACACTCCAGCtaagtttcaaaataaatctatatcaaGTCTCAGCATGACTTGTGCATATTGTGGAGAAGTATGTCGTTCTAGAACTGACCTAGAATCTCATACAAGGATTCAACATGCATCAAATGAACCTGGGGGCCGTCACAAATGCAATATTTGTGACGAAGTCTGTCCTTCAGGTGCAACTCTAGCAGAACATAAACTGCAAAAACACTGTAAAATTCAACTAAGTGACACGTGTATTGTTTGTCGAGGAAATTTATCTTCAGAATCACAATTTTTAGAACACGTTCAAAGACACAGTTTGGAAAACGTGGATCCTCAACAGAGATTAGATGGTTCTCTTCCCCATCTTCCTGCAGCGTGTGTAGTTTGCAGACAGACACTGATCAGCGATTTGGAATGTCGTCTTCATGCTAGACATCATTTGAGAGCTTCTACTGGTCCTCACAGTGTGGGATCTAGCCCTAGTCCCAatcaaaaaaatcagaatCCAAGTTGTTGTCTTTGCTTAAGAGATTATTCTGGTGATGACTTTGTTAATTTGCCACCAAGTCATGTAAGTGGAGGAGGACAATCTTTGAGAGTCTGCAAGTCTTGCTATATTCGTCACTCTCAAGGTTTACCTATTTTGAATTCATATGAATCTGTTAGATCTAAATGTGATGATTCTTGGGcatctaataataaagatgGACAATGGGAtggatcgaaaaataaatgggAATcggagaataaatataaagaaaatagaaatggaaTGATTGATAATAAGAGATGTCAAGATTGTGGAGTGAAATTTGAGGATTCCGAAGAGGTGGAAAAACATAGGATAATAGAGCATGAGAAGACTGGAGCTGCATCTAATACATATACGTGTATACAATgtcaaATGTCATTCGCAACAGAAGCAAAGATTCAGCagcatataaagaaagaacatTTGGAAGTATCAGAAAAAACTTCCATGGAGGCGTTACGATgtcatttatgtttatttgaaGCTAATAGTCCATTACAGTTGCAAAGCCATTTGATAGAGCACACTTTTGCAGGATGTGCCGCTCTCAGCTGTTATATTTGCCAATCTCTTTTCACTGCACCTATTGGTCTTCAGaatcataTGCTTCAAGAACACGGTTTGGGTGCACGCCCATATGATTGTTCCCAGtgcacattaaaatttttcttcagagCAGAATTAGATCACCATATGTTAACATTCCATCGATCCGGAGACGTATCCTCGCCTGATGAAGATATACAAAacaatattgaaacaaaagcAAGAAACactgaagaaaataattctgacGAAAAAATAATGGTGAAAGAAGAATTGTTACCGGAAGGTgcagatgaagaagaagagatcAACGTGGATGAACAAGTAGAAGAGAACGAGCAAAAGGAAGACAAACAGTTAGAATTCgagacaaaattaaaaactgaaaTCGAGGAAGAAAACATTCTTCAGTCTTCTATTTCCGAGAAAATGGAATCGTGA
Protein Sequence: MSRRKQAKPRSLKRDEEWDDGNEQNVLEVTEQDNEATGIKQDEEEEEEEEELQRAFSHHSEEYLQEGRPSSVQGLDLENQNSLDSEALGTGSSSWQSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGSNATAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSQGSAKDIDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPKSGLKSSQGSVSTTPILNSPLKLACMYCTRDSFNCMQQLQMHVHTMHQAILSGETVAVSPSTNRANEQIGYQHGEKNLDRSEGTSKEHNRKYQDDSERSMEKDHYENAFTCNQCTMKFSTLGSLRDHLISIHRTDSFNSALMMCPLCGIPCASAAAYAEHYVLQHCENRSIAPLESKDYIDAKMNGSYESKSSRNQKSREQISSSEPADLTSKHTTTMENNYSAGTLLCGQCGAALKDFESFREHLARHLQANHRNDAVRHSCPKCEATFQDREDMFVHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSPGNAPGEGKSFFRSESEMTNHVRNVHAPPTVSNNSPVARSPASTPGITGNSGPRCVFCGICCTSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHIAQAHHSSSHQGIIRSSSRENGRIGRPPRLQEETKSQKRGRSPASSNNNTVNQRDNNNKRPNYSNTSSQQCDLCERGEFSNETELQAHKKLVHTPAKFQNKSISSLSMTCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLSSESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGPHSVGSSPSPNQKNQNPSCCLCLRDYSGDDFVNLPPSHVSGGGQSLRVCKSCYIRHSQGLPILNSYESVRSKCDDSWASNNKDGQWDGSKNKWESENKYKENRNGMIDNKRCQDCGVKFEDSEEVEKHRIIEHEKTGAASNTYTCIQCQMSFATEAKIQQHIKKEHLEVSEKTSMEALRCHLCLFEANSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRSGDVSSPDEDIQNNIETKARNTEENNSDEKIMVKEELLPEGADEEEEINVDEQVEENEQKEDKQLEFETKLKTEIEEENILQSSISEKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00142642;
80% Identity: -