Basic Information

Insect: Andrena praecox
Gene Symbol: znf423
Assembly: GCA_963932275.1
Location: OZ010732.1:46783949-46799755[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 9.8e-06 0.0014 20.0 1.5 1 23 92 114 92 114 0.98

2 20 0.56 81 5.0 3.9 1 23 120 142 120 142 0.97

3 20 1.2e-06 0.00018 22.8 4.3 1 23 148 170 148 170 0.99

4 20 0.00026 0.038 15.5 0.2 1 23 176 198 176 198 0.99

5 20 0.00032 0.046 15.2 0.6 1 23 352 375 352 375 0.95

6 20 0.49 71 5.2 0.0 2 23 386 408 385 408 0.88

7 20 0.24 35 6.2 0.1 3 23 472 492 471 492 0.97

8 20 0.0077 1.1 10.9 0.2 1 23 504 526 504 526 0.97

9 20 0.017 2.4 9.8 0.3 1 23 535 558 535 558 0.92

10 20 4.4 6.3e+02 2.2 0.2 1 23 563 586 563 586 0.91

11 20 0.19 28 6.5 2.0 2 23 660 681 660 681 0.96

12 20 0.006 0.88 11.2 0.1 1 23 686 709 686 710 0.94

13 20 3.9 5.6e+02 2.4 0.1 2 23 769 792 768 792 0.81

14 20 0.00024 0.035 15.6 1.0 2 23 808 830 807 830 0.96

15 20 1.3 1.9e+02 3.9 0.6 1 12 839 850 839 862 0.76

16 20 0.007 1 11.0 2.1 2 23 1052 1074 1051 1074 0.96

17 20 0.086 13 7.6 0.3 1 23 1084 1107 1084 1107 0.96

18 20 1.5 2.1e+02 3.7 0.4 2 23 1120 1141 1119 1141 0.94

19 20 0.56 81 5.0 0.1 2 23 1150 1172 1149 1172 0.93

20 20 0.12 18 7.1 3.0 1 23 1179 1202 1179 1202 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	9.8e-06	0.0014	20.0	1.5	1	23	92	114	92	114	0.98
2	20	0.56	81	5.0	3.9	1	23	120	142	120	142	0.97
3	20	1.2e-06	0.00018	22.8	4.3	1	23	148	170	148	170	0.99
4	20	0.00026	0.038	15.5	0.2	1	23	176	198	176	198	0.99
5	20	0.00032	0.046	15.2	0.6	1	23	352	375	352	375	0.95
6	20	0.49	71	5.2	0.0	2	23	386	408	385	408	0.88
7	20	0.24	35	6.2	0.1	3	23	472	492	471	492	0.97
8	20	0.0077	1.1	10.9	0.2	1	23	504	526	504	526	0.97
9	20	0.017	2.4	9.8	0.3	1	23	535	558	535	558	0.92
10	20	4.4	6.3e+02	2.2	0.2	1	23	563	586	563	586	0.91
11	20	0.19	28	6.5	2.0	2	23	660	681	660	681	0.96
12	20	0.006	0.88	11.2	0.1	1	23	686	709	686	710	0.94
13	20	3.9	5.6e+02	2.4	0.1	2	23	769	792	768	792	0.81
14	20	0.00024	0.035	15.6	1.0	2	23	808	830	807	830	0.96
15	20	1.3	1.9e+02	3.9	0.6	1	12	839	850	839	862	0.76
16	20	0.007	1	11.0	2.1	2	23	1052	1074	1051	1074	0.96
17	20	0.086	13	7.6	0.3	1	23	1084	1107	1084	1107	0.96
18	20	1.5	2.1e+02	3.7	0.4	2	23	1120	1141	1119	1141	0.94
19	20	0.56	81	5.0	0.1	2	23	1150	1172	1149	1172	0.93
20	20	0.12	18	7.1	3.0	1	23	1179	1202	1179	1202	0.97

Sequence Information

Coding Sequence: ATGTTGTTCAAGGGGAACAGCTCGAGGCTGGAGTTGTTGATAGGGAAGATCCAGGCTCATAAGGAACCCACTCAGGAGGAGCACCATAAGTCTAAAGAGGCCTTGGGGACCGGAAGCTCGTCCTGGCACAGCGAGGATGGCGGGCCGAACTCGCGCCGAGGAGGCGAGACGCCGTCGTCCTGCGCGACGCCGACGTCGGCCAGCTTCCCGTCGGAGCCTGAAGTGGATGCTGACGTCGGCGTCAACGCCGACGGAAACAACGCTGCCGCGCCTTATCCTTGCCAGTTCTGCGACCGCACGTTCCCGCGGTTGAGCTACCTGAAGAAACACGAACAGAGTCACGGCGATCAGATGCCGTATCGATGCAGCTGGTGCGCGAGGCTGTTCAAACATAAGCGCAGCAGAGATCGACACGTGAAGCTTCACACGGGAGATCGAAGATACCGATGCACGCACTGCGAAGCAGCTTTCTCTCGGAGCGACCACCTGAAGATCCACATGAAGACCCACGACACCCAGAAGCCCTACCAGTGCACAGCCTGCTCTAGGGGCTACAACACGGCCGCGGCGTTGACCTCCCACATGCAGTCGCACAAGAAGCTCCATCAGTCGCAGGTCGCCAGCAAGCTGCAGGACGTGGAGTACGGTCGGCGCAGCGTCTCCTCGCACAGCACATCCTCGCCCCCTGTCGCGAGCTCCCCGTCGCCATCGCTGAACCTGTCCCTCGCCCCGAAGTCCGGGGTGAAGGGGTCGCAGGGCAGCGCCTCTACCACGCCGATCCTGAGCTCGCCCCTCAAGCTCGCTTGCATGTACTGCACCAGGGACTCGTTCAGCTGCATGCAACAGCTGCAGATGCACGTGCACACGATGCACCAGGCGATCCTGAGCGGCGAGAGCGTGGCTGTGCCGCCTTCGCCCAGCAGGAGCGGCGAGCAGCTCGCCTACCAGCGCGACAAGGGGCTGGACCGAGCCGAGGGTGCGAAGGACCACCGCGAGAGGAAGTACCAAGAGGAGTCGGAGAGAAGAACGGAGAAGGAGCACTACGAGAACTCGTTCACCTGCAACCAGTGCACCATGAAGTTCTCCACGTTGGGTTCCCTGCGGGACCACCTGGTATCCATCCACAGGACAGACGGCTTCGGCTCCGCCCTGATGATGTGTCCCCTCTGCGGCATCCCGTGCGCCTCTGCGGCTGCCTACGCCGAGCACTACGTTCTCCAGCACTGCGAGAACAGGCGGATGGGCGCCCTGGAGGGTCGTGAGTACCTGGACGCGAAGATGAACGGCAGCTACGGGGACGCGAAGAGCTCGCGGGCGGAGAAGCCTGTGGACCAGTCGCTCTCCGAGCCGGCCGACCTCACCAGCAAGCATTCCAGGTCGACGGAGGGCAGCTACACCGCGGGGACCCTGCTCTGCGGCCAATGTGGCGCCGCTCTCAAGGACTTCGAGTCCTTCAGGGAGCACTTGGCCAGGCATTTGCAAGCCGACCACCGCAACGACGCCATGAGGCATCCCTGCCCGAAATGCGAGGCTGCCTTCCAGGACAGGGAGGACATGCTGGCGCACCTGACGAAGCACTACCTGGGTCAGATCAGCAAGGAGTACGCTTGCGGGGCCTGCAAGAAGCTCTACCCTCATCCTGACCTTCTGCAGAGACACCTGCTCGATAGCCACGCTCATCATCTCTATAGATGCGCCCTGTGCAGGGACACGTTCGACTCCAGGGTGGCGATACAGGTGCACTTCGCTGTTAAGCACAGTCAGGAGTGCAGGATCTATCGCTGCAACGCGTGCACCGCTCCCAATAACGAGAACTCGCCTGGGAACGCGCCCGGGGAAGGCAGGAGCTTCTTCAGGAGCGAGTCGGAGATGGCTAGCCACGTGAGGAGCGTCCACGCGCCGCCCGCCATGTCGAACAGCAGCCCCGTGGCCAGGAGTCCTGCCTCCACACCTGGTGTAACGAGTGGCTCAGGGCCTAGGTGCGTCTTCTGCGGCGTCTGCTGCAGCTCGGAGCTGGAGCTGCAGCTTCACCTGGCCAGCCACTCGAGCAACCTGTACAGGTGCCCAATCTGCAGGGAGGGCTTCGCCGTTGAGTTCCTGCTCGACAGGCATATCGCCCAGGCGCACCACTCGAGCGACCATCAGGCCAGGGAGAACGGGCGGATCGGGAGGCCCGCGCCTAGGTCCCAAGAAGAGCCGAAGTCCCAGAAAAGGGGCCGCTCCCCAGCGTCCAGCAACAACAACTCCCTGAACCAGCGGGACAACAACAACAAACGAGCGAACTACACCAGCACCGGGGCCCAGCAGTGCGAGCTCTGCGAGAGGGGCGAGTTCGCGAACGAAGCGGAGCTCCAGGCGCACAAGAAGCTGGCTCACGCGGCTGCCAAGCCTCAGAGCAAGTCTCTGTCCAGCTTGAGCATGACGTGCGCCTATTGCGGCGAGGTATGCCGCTCCAGAACCGAGCTGGAGTCCCACACGAGGATCCAGCACGCCTCGAACGAGCCCGGAGGACGCCACAAGTGCAACATCTGCGACGAGGTCTGCCCGTCCGGGGCCATCCTGGCCGAGCACAAGCTGCAGAAGCACTGCAAGATCCAGCTGAGCGACACCTGCATCGTGTGCCGCGGTAGCCTGGCCACGGAGTCGCAGTTCCTCGAGCACGTGCAGAGACACAGCCTGGAGAACGTGGACCCTCAACAGAGGCTAGACGGCTCGCTCCCTCACCTGCCGGCCGCGTGTGTCGTCTGCAGGCAGACATTGATCAGCGACCTGGAGTGTCGCCTCCACGCCAGACACCATCTCAGAGCCTCCACTGGGTCCAGGAGCGCTGGCTCCAGCCCCAGCCCGAACCAGAAGAACCATAACTCGGGCTGCTGCCTTTGCCTCAGGGACTACTCCGTCGACGACTTCGTCAGCCTACCTCCCAATCACATCAGCGGCGGCGGACAGTCCCTCAGGGTCTGCAAGTCCTGCTACATCCGCCACTCTCAGGGCCTGCCTATCCTGAACTCACCCTACGAGCATGCTAGAACTAAAGGCGACAGAGGCTGGATATCCAGCAAGGACCCTCAGTGGGACGGGTCCAGGGACAGGTGGGACTCCGAGCGCGCGTTTAAGGCAGAAGACAGGGGCAGCGAAGGGAATGACGGCAAGAGGTGCCAGCATTGCGGGGTGAAGTTCGAGGATCCTGAGGAAGCGGAGAAACACAGGCACACGGAGCATGAGAAGACTGGGTCTGGGTCGAGCACGTACACGTGTATACAGTGTCAGATGTCGTTTCCGACGGAAGCTAAGATACAGCAGCACGTGAGAAAGGAGCATCTGGAGTCGTCGGGGAAAGCATCTGTCGAGGCACTGCGCTGCCACTTGTGCCTCTTCGAAGCTAGCAGTCCGTTGCAATTGCAGAGCCACTTGATAGAGCATACGTTCGCTGGGTGCGCTGCTCTCAGTTGCTACATTTGCCAGTCCCTCTTCACGGCGCCCATTGGACTTCAGaACCACATGCTGCAGGAACACGGTCTGGGAGCTCGACCGTACGATTGCTCCAAGTGCACGCTTAAGTTCTTCTTCAGGGCCGAGCTGGACCACCACGTGCTAACGTTCCATCGGTCCGGAGGGCCTCCATCGCCCATTGAGAACCCGCAGAACTCGGTCGAGGCGAAACCTAGAGACCCGAAGGAGCAGAACAGTAGCGAGGGTGTGATGGTGAAGGAGGAAGTGTTGCCTGACGCCGCAGACGAAGAAGAGGAGATAAACGTCGACGAGCAAGTGGAGCAGGACGAACAGAAGGCGGACAAGCGGGCAGAGTCAGAGCAGGAGATGAAAATCGAGGTCGACGAGGAAGCTATTCCGGAAAAAACAGAGTCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPTQEEHHKSKEALGTGSSSWHSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGNNAAAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKLHQSQVASKLQDVEYGRRSVSSHSTSSPPVASSPSPSLNLSLAPKSGVKGSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGESVAVPPSPSRSGEQLAYQRDKGLDRAEGAKDHRERKYQEESERRTEKEHYENSFTCNQCTMKFSTLGSLRDHLVSIHRTDGFGSALMMCPLCGIPCASAAAYAEHYVLQHCENRRMGALEGREYLDAKMNGSYGDAKSSRAEKPVDQSLSEPADLTSKHSRSTEGSYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDAMRHPCPKCEAAFQDREDMLAHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTAPNNENSPGNAPGEGRSFFRSESEMASHVRSVHAPPAMSNSSPVARSPASTPGVTSGSGPRCVFCGVCCSSELELQLHLASHSSNLYRCPICREGFAVEFLLDRHIAQAHHSSDHQARENGRIGRPAPRSQEEPKSQKRGRSPASSNNNSLNQRDNNNKRANYTSTGAQQCELCERGEFANEAELQAHKKLAHAAAKPQSKSLSSLSMTCAYCGEVCRSRTELESHTRIQHASNEPGGRHKCNICDEVCPSGAILAEHKLQKHCKIQLSDTCIVCRGSLATESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGSRSAGSSPSPNQKNHNSGCCLCLRDYSVDDFVSLPPNHISGGGQSLRVCKSCYIRHSQGLPILNSPYEHARTKGDRGWISSKDPQWDGSRDRWDSERAFKAEDRGSEGNDGKRCQHCGVKFEDPEEAEKHRHTEHEKTGSGSSTYTCIQCQMSFPTEAKIQQHVRKEHLESSGKASVEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQNHMLQEHGLGARPYDCSKCTLKFFFRAELDHHVLTFHRSGGPPSPIENPQNSVEAKPRDPKEQNSSEGVMVKEEVLPDAADEEEEINVDEQVEQDEQKADKRAESEQEMKIEVDEEAIPEKTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00087426;
80% Identity: -