Basic Information

Insect: Melipona beecheii
Gene Symbol: znf423
Assembly: GCA_032399605.1
Location: JAUCMO010000302.1:2365094-2384308[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 8.9e-06 0.00073 20.0 1.5 1 23 101 123 101 123 0.98

2 20 0.51 42 5.0 3.9 1 23 129 151 129 151 0.97

3 20 1.1e-06 9.1e-05 22.8 4.3 1 23 157 179 157 179 0.99

4 20 3.1e-05 0.0025 18.3 0.4 1 23 185 207 185 207 0.99

5 20 0.00043 0.036 14.7 0.6 1 23 361 384 361 384 0.95

6 20 0.14 11 6.8 0.1 2 23 395 417 394 417 0.88

7 20 0.22 18 6.2 0.1 3 23 479 499 478 499 0.97

8 20 0.059 4.8 8.0 0.7 1 23 510 532 510 532 0.96

9 20 0.015 1.2 9.8 0.3 1 23 541 564 541 564 0.92

10 20 4 3.3e+02 2.2 0.2 1 23 569 592 569 592 0.91

11 20 0.11 8.7 7.1 2.0 2 23 666 687 666 687 0.96

12 20 0.011 0.86 10.3 0.2 1 23 692 715 692 716 0.94

13 20 0.85 70 4.3 0.2 2 23 779 802 778 802 0.85

14 20 0.00019 0.016 15.8 1.1 2 23 818 840 817 840 0.96

15 20 0.044 3.7 8.3 1.0 1 23 849 872 849 872 0.93

16 20 0.0013 0.11 13.2 0.3 2 23 1056 1078 1055 1078 0.95

17 20 0.079 6.5 7.6 0.3 1 23 1090 1113 1090 1113 0.96

18 20 1.8 1.5e+02 3.3 0.3 2 23 1126 1147 1125 1147 0.94

19 20 0.18 15 6.4 0.1 2 23 1156 1178 1155 1178 0.94

20 20 0.0095 0.78 10.4 2.5 1 23 1185 1208 1185 1208 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	8.9e-06	0.00073	20.0	1.5	1	23	101	123	101	123	0.98
2	20	0.51	42	5.0	3.9	1	23	129	151	129	151	0.97
3	20	1.1e-06	9.1e-05	22.8	4.3	1	23	157	179	157	179	0.99
4	20	3.1e-05	0.0025	18.3	0.4	1	23	185	207	185	207	0.99
5	20	0.00043	0.036	14.7	0.6	1	23	361	384	361	384	0.95
6	20	0.14	11	6.8	0.1	2	23	395	417	394	417	0.88
7	20	0.22	18	6.2	0.1	3	23	479	499	478	499	0.97
8	20	0.059	4.8	8.0	0.7	1	23	510	532	510	532	0.96
9	20	0.015	1.2	9.8	0.3	1	23	541	564	541	564	0.92
10	20	4	3.3e+02	2.2	0.2	1	23	569	592	569	592	0.91
11	20	0.11	8.7	7.1	2.0	2	23	666	687	666	687	0.96
12	20	0.011	0.86	10.3	0.2	1	23	692	715	692	716	0.94
13	20	0.85	70	4.3	0.2	2	23	779	802	778	802	0.85
14	20	0.00019	0.016	15.8	1.1	2	23	818	840	817	840	0.96
15	20	0.044	3.7	8.3	1.0	1	23	849	872	849	872	0.93
16	20	0.0013	0.11	13.2	0.3	2	23	1056	1078	1055	1078	0.95
17	20	0.079	6.5	7.6	0.3	1	23	1090	1113	1090	1113	0.96
18	20	1.8	1.5e+02	3.3	0.3	2	23	1126	1147	1125	1147	0.94
19	20	0.18	15	6.4	0.1	2	23	1156	1178	1155	1178	0.94
20	20	0.0095	0.78	10.4	2.5	1	23	1185	1208	1185	1208	0.97

Sequence Information

Coding Sequence: atgCGTCACTTCGCAATTGGATTAAAGGTGATAGAAAAGCAATTCGCATTCGCAGTATCTATGATATGGAGTGAGCCTAAAGATAATTTGAGTGATTACTATTTTTGTGCCATAATTGTGAAGGAAGCTTTGGGAACCGGAAGTTCATCGTGGCAGAGCGAAGATGGTGGTCCAAACTCACGACGCGGTGGTGAGACGCCCTCTTCTTGCGCAACACCGACGTCAGCCAGCTTCCCGTCGGAGCCTGAGGTGGATGCTGACATCGGCGTTAATGCCGACGGAACCAACGCTATCGCACCTTATCCTTGTCAATTTTGCGACCGAACGTTTCCGCGACTTAGCTACCTGAAAAAACACGAACAGAGTCACGGAGATCAAATGCCATATAGATGCAGTTGGTGTGCCAGATTATTCAAACATAAACGCAGTAGAGATCGACACGTGAAGCTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGAAGCTGCTTTCTCCAGAAGTGACCACTTGAAGATTCATATGAAGACCCATGACACTCAAAAGCCGTATCAGTGCACAACATGTTCCAGAGGCTACAACACAGCAGCTGCCCTAACATCCCACATGCAATCTCACAAGAAACATCATCAATCTCAAACATCCAAACTTCAGGACATCGACTACGGTAGAAGAAGTGTATCCTCTCACAGTACATCATCGCCGCCAATACCAAGCTCTCCATCGCCATCTTTAAACATAGTCTTGAATTCAAAAACTTGTATGAAAAGTACTCAAGGAAGTGCTTCGACAACTCCGATTCTGAGCTCTCCACTGAAGTTAGCTTGCATGTATTGTACCAGAGATACCTTCAGTTGTATGCAACAACTCCAGATGCACGTGCATACGATGCACCAAGCTATCTTAAGTGGAGAAACTGTTGCAGTATCTCCATCAACTAATAGAATCAATGAACAAATAAGTTATCAACATGAAAAGACTTTCGACAGAAAGCCAGAAGGATCATCTAAAGAACACAAAAGGAAATATCAAGATGATTCAGAAAAATCTATAGAGAAAGATCACTATGAAAACGCATTTACATGCAGTCAATGTACTatgaaattttctacgttAGGCTCACTAAGGGATCATTTGGTTTCAATTCATAGAACCGATGGTTTTGGCTCTGCTTTGATGATGTGTCCTCTTTGTGGCATTCCTTGTACTTCTGCAGCGACTTATGCAGAACACTATGTTCTCCAACATTGTGAAAATCGAAGAACAGATCTAGAAATTAGAGACTATACAGATTCTAAGATGAATGGAAATTATGACACTAAAAGTATCAGGAGTCAGAAATGTAGGGAGCAAACGTCTTCTGAGCCAGCTAATTTGACCAATAAGCATTCCACTGGTACAGAAAGTAATTATACAGCTGGTACATTGTTATGTGGACAGTGTGGAGCTGCTTTAAAGGACTTCGAATCATTCAGGGAACACTTAGCTAGACATCTTCAAGCTGATCATAGAAATGATGTTAGACATCCTTGTTTAAAGTGTGAAGCCACTTTTCAAGATAGGGAAGACATGTTGGTACATTTAACGAAACATTATTTGAGCCAGATTAGTAAAGAATATGCTTGTGGTGCATGTAAGAAACTTTATCCTCATCCTGATCTTCTTCAGAGGCATTTACTCGACAGTCATGCTCATCATCTCTATCGATGCGCCTTGTGCAGAGATACATTTGATTCTAGAGTGGCAATACAGGTTCATTTTGCTGTGAAACACAGTCAAGAATGCAGAATCTATAGATGCAATGCTTGCACAGTGtctaataatgaaaattcaccGGGAAATGCGccagaagaaggaaaaagctTCTTCCGAAGTGAGTCTGAAATGGCAAACCATGTAAAAAATGTCCACGCACCTCCAACGATGTCAAATAATAGTCCTGTGGCTAGGAGTCCTGCTTCCACTCCAGGAATAACTGGGAATTCCGGACCAAGATGCGTCTTTTGTGGAATCTGTTGTAGTTCCGAGCTGGAACTACAACTCCATTTGGCCAGCCATTCTGCTAACTTATATAGATGTCCTGTTTGTAGAGAAGGATTTgccgtggaatttttattagatagACATATTACTCAAGCACATCATTCTAGTGACCATCAGGATGTCGTGAGAAGTAATTCTAGAGAGAATGGAAGAATTGGTAGACTACCAAGATTACAGGAAGAGgCTAAATCCCAAAAAAGAGGTCGCTCTCCAGCCTCCAGCAACAACAACTCTTTGAATCAACGTGACAACAATAAACGTCCAAATTACACCAATGCATCCTCTCAACAATGCGATCTCTgcgaaagaggaaaattttccaacgaagcAGAACTTCAAGCTCACAAAAAATTGGTTCACACTCCGatcaagtttcaaaataaGTCTATATCGAGTCTTAGCATGACTTGTGCATACTGTGGAGAAGTATGCCGTTCTAGAACTGATTTAGAATCTCATACAAGAATCCAACATGCATCAAGTGAACCTGGAGGACGCCACAAGTGTAATATTTGTGACGAAGTGTGCCCATCAGGAGCAACACTTGCAGAACATAAACTTCAGAAACATTGTAAGATTCAATTATGTGACACATGTATCGTTTGTCGAGGAAACCTATTTTCAGAATCACAGTTTCTAGAACATGTGCAAAGACACAGTCTGGAGAATGTGGATCCTCAGCAGAGATTAGATGGTTCTCTTCCTCATCTTCCTGCAGCTTGTGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAATGTCGTCTCCATGCCAGACATCACTTAAGAACTTCTGGCTCTCATAGTGTGGCATCCAGTCCCAGTCCCAACCAAAAGAATCAGAGTCCAAGTTGTTGTCtttgtttaagaaattattcagCTGATGACTTTGTTAATTTACCTCCAAGTCATATAAGTGGAGGAGGACAGTCTTTAAGGGTTTGCAAATCTTGTTACATTCGACACTCTCAGGGTCTACCTATTTTGAATTCACCTTACGAGCCTATTAAGTGTGATGATTCTTGGACATCCAGTAATAAAAATGGACAATGGAATAAATCAAAGGATAAATGGGAAACCGAGaataaagaagataaaaacGAGGGGAATGATAGTAAGAAGTGTCAAGATTGTGGGGTGAAATTTGAGGATTCTGACAAGGTGGAGAAACATAGGATAGTCGAGCATGAAAAAGTTATAAGTGGAGTTATGTTGAACACATACACATGTATACAGTGTCAGatgTCATTCCCAACAGAGGCAAAGATTCAGCAACATGTAAGAAAAGAACATCTAGAAACATCGGGAAGAACTTCCATAGAAACATTACGATGTCATCTGTGTCTTTTTGAAGCTAGCAGTCCATTAGAATTGCAAAGCCATTTGATAGAGCATACTTTCGCAGGATGTGCCGCTCTCAGCTGTTACATTTGCCAATCTCTCTTTACCGCACCTGCTGGTCTTCAGAATCATATGCTTCAAGAACACGGTCTGGGTGCTCGTCCCTATGATTGTTCCGAATGTACACTCAAATTCTTCTTCAGAGCAGAACTAGATCATCATATGTTAACATTTCACCGATCAGGAGACGTGCCATCACCCAATAAAAATACCACACAGAATAccatcgaaataaaaaaaaaagatgccgaaaaaagaaattgtgatGAAGGAGTGActgtgaaagaagaaatggtTCTAGGAgcagcagaagaagaagaagagatcaACGTGGATGAACAAATAGAACAGGATGGTCAAAACGCAGATCAACAATCAGAAATCGagacgaaattaaaaactgaGCTCGAGGAAGAATTTATTCCCGAAAAAATGGAATCGTGA
Protein Sequence: MRHFAIGLKVIEKQFAFAVSMIWSEPKDNLSDYYFCAIIVKEALGTGSSSWQSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADIGVNADGTNAIAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTTCSRGYNTAAALTSHMQSHKKHHQSQTSKLQDIDYGRRSVSSHSTSSPPIPSSPSPSLNIVLNSKTCMKSTQGSASTTPILSSPLKLACMYCTRDTFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRINEQISYQHEKTFDRKPEGSSKEHKRKYQDDSEKSIEKDHYENAFTCSQCTMKFSTLGSLRDHLVSIHRTDGFGSALMMCPLCGIPCTSAATYAEHYVLQHCENRRTDLEIRDYTDSKMNGNYDTKSIRSQKCREQTSSEPANLTNKHSTGTESNYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDVRHPCLKCEATFQDREDMLVHLTKHYLSQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSPGNAPEEGKSFFRSESEMANHVKNVHAPPTMSNNSPVARSPASTPGITGNSGPRCVFCGICCSSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHITQAHHSSDHQDVVRSNSRENGRIGRLPRLQEEAKSQKRGRSPASSNNNSLNQRDNNKRPNYTNASSQQCDLCERGKFSNEAELQAHKKLVHTPIKFQNKSISSLSMTCAYCGEVCRSRTDLESHTRIQHASSEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLCDTCIVCRGNLFSESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRTSGSHSVASSPSPNQKNQSPSCCLCLRNYSADDFVNLPPSHISGGGQSLRVCKSCYIRHSQGLPILNSPYEPIKCDDSWTSSNKNGQWNKSKDKWETENKEDKNEGNDSKKCQDCGVKFEDSDKVEKHRIVEHEKVISGVMLNTYTCIQCQMSFPTEAKIQQHVRKEHLETSGRTSIETLRCHLCLFEASSPLELQSHLIEHTFAGCAALSCYICQSLFTAPAGLQNHMLQEHGLGARPYDCSECTLKFFFRAELDHHMLTFHRSGDVPSPNKNTTQNTIEIKKKDAEKRNCDEGVTVKEEMVLGAAEEEEEINVDEQIEQDGQNADQQSEIETKLKTELEEEFIPEKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_01420489;
80% Identity: -