Basic Information

Insect: Frieseomelitta varia
Gene Symbol: znf423
Assembly: GCA_011392965.1
Location: WNWW01000244.1:353182-369527[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 1.1e-05 0.00066 19.2 1.5 1 23 59 81 59 81 0.97

2 21 0.34 21 5.1 3.9 1 23 87 109 87 109 0.97

3 21 7.4e-07 4.5e-05 22.9 4.3 1 23 115 137 115 137 0.99

4 21 2.1e-05 0.0013 18.3 0.4 1 23 143 165 143 165 0.99

5 21 0.00029 0.018 14.7 0.6 1 23 319 342 319 342 0.95

6 21 0.091 5.6 6.9 0.1 2 23 353 375 352 375 0.88

7 21 0.15 9 6.2 0.1 3 23 438 458 437 458 0.97

8 21 0.039 2.4 8.0 0.7 1 23 469 491 469 491 0.96

9 21 0.01 0.62 9.9 0.3 1 23 500 523 500 523 0.92

10 21 2.7 1.6e+02 2.2 0.2 1 23 528 551 528 551 0.91

11 21 9.3 5.7e+02 0.5 0.2 10 23 583 597 581 597 0.93

12 21 0.071 4.4 7.2 2.0 2 23 625 646 625 646 0.96

13 21 0.007 0.43 10.4 0.2 1 23 651 674 651 675 0.94

14 21 0.87 54 3.8 0.1 2 23 739 762 738 762 0.83

15 21 0.00013 0.008 15.8 1.1 2 23 778 800 777 800 0.96

16 21 0.03 1.8 8.4 1.0 1 23 809 832 809 832 0.93

17 21 0.00085 0.053 13.2 0.3 2 23 1016 1038 1015 1038 0.95

18 21 0.052 3.2 7.6 0.3 1 23 1050 1073 1050 1073 0.96

19 21 1.2 75 3.3 0.3 2 23 1086 1107 1085 1107 0.94

20 21 0.12 7.5 6.4 0.1 2 23 1116 1138 1115 1138 0.94

21 21 0.016 0.99 9.2 3.1 1 23 1145 1168 1145 1168 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	1.1e-05	0.00066	19.2	1.5	1	23	59	81	59	81	0.97
2	21	0.34	21	5.1	3.9	1	23	87	109	87	109	0.97
3	21	7.4e-07	4.5e-05	22.9	4.3	1	23	115	137	115	137	0.99
4	21	2.1e-05	0.0013	18.3	0.4	1	23	143	165	143	165	0.99
5	21	0.00029	0.018	14.7	0.6	1	23	319	342	319	342	0.95
6	21	0.091	5.6	6.9	0.1	2	23	353	375	352	375	0.88
7	21	0.15	9	6.2	0.1	3	23	438	458	437	458	0.97
8	21	0.039	2.4	8.0	0.7	1	23	469	491	469	491	0.96
9	21	0.01	0.62	9.9	0.3	1	23	500	523	500	523	0.92
10	21	2.7	1.6e+02	2.2	0.2	1	23	528	551	528	551	0.91
11	21	9.3	5.7e+02	0.5	0.2	10	23	583	597	581	597	0.93
12	21	0.071	4.4	7.2	2.0	2	23	625	646	625	646	0.96
13	21	0.007	0.43	10.4	0.2	1	23	651	674	651	675	0.94
14	21	0.87	54	3.8	0.1	2	23	739	762	738	762	0.83
15	21	0.00013	0.008	15.8	1.1	2	23	778	800	777	800	0.96
16	21	0.03	1.8	8.4	1.0	1	23	809	832	809	832	0.93
17	21	0.00085	0.053	13.2	0.3	2	23	1016	1038	1015	1038	0.95
18	21	0.052	3.2	7.6	0.3	1	23	1050	1073	1050	1073	0.96
19	21	1.2	75	3.3	0.3	2	23	1086	1107	1085	1107	0.94
20	21	0.12	7.5	6.4	0.1	2	23	1116	1138	1115	1138	0.94
21	21	0.016	0.99	9.2	3.1	1	23	1145	1168	1145	1168	0.97

Sequence Information

Coding Sequence: GCTTTGGGGACCGGAAGTTCATCGTGGCAGAGCGAAGATGGTGGTCCAAACTCACGACGCGGTGGTGAGACGCCCTCTTCTTGCGCAACGCCGACGTCAGCCAGCTTCCCGTCGGAGCCTGAAGTGGATGCTGACGTCGGCGTTAATGCCGACGGAACCAACGCTACCGCACCTTATCCTTGTCAATTCTGCGACCGAACGTTTCCGCGACTTAGCTACCTGAAAAAACACGAACAGAATCACGGAGATCAAATGCCATATAGATGCAGTTGGTGTGCCAGATTATTCAAACACAAACGCAGTAGAGATCGACACGTGAAGCTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGAAGCTGCTTTCTCCAGAAGtgaCCACTTGAAGATTCATATGAAGACCCATGACACTCAAAAGCCGTATCAGTGCACAACCTGTTCTAGAGGCTACAACACAGCAGCTGCCCTAACATCCCACATGCAATCTCACAAGAAACATCATCAATCTCAAACATCCAAACTTCAGGACGTCGACTATGGTAGAAGAAGTGTATCCTCTCATAGTACATCATCGCCGCCAATACCAAGCTCTCCATCGCCATCTCTAAATATAGTCTTGAATTCAAAAACTTGTATGAAAAGTACTCAAGGAAGTGCTTCGACAACTCCGATTCTGAGCTCTCCACTGAAGTTAGCTTGCATGTATTGTACCAGAGATACCTTCAGTTGTATGCAACAACTCCAGATGCACGTGCACACGATGCACCAAGCTATCTTAAGTGGAGAAACTGTTGCAGTATCTCCATCAACTAACAGAATCAATGAACAAATAAGTTATCAGAATGAAAAGACTTTCGACAGAAAGCCAGAAGGATCATCTAAAGAACACAAAAGGAAATATCAAGATGATTCAGAAAAATCTATAGAAAAAGATCACTATGAAAACGCATTTACATGTAGTCAGTGTACTATGAAGTTCTCTACGTTAGGCTCATTGAGGGATCATTTGGTTTCGATTCATAGAACCGATGGTTTTGGCTCTGCTTTGATGATGTGTCCTCTTTGTGGCATTCCTTGTACTTCTGCAGCGACTTATGCAGAACACTATGTTCTCCAACATTGTGAAAATCGAAGAACAGGTCTCCTAGAAATTAGAGACTATACAGATTCTAAGATGAATGGAAATTATGACACTAAAAGTAACAGGAGTCAGAAATGTAGGGAGCAAACGTCTTCTGAGCCAGCTGATTTGACCAACAAGCATTCTACCAGTACAGAAAGTAATTATACAGCTGGTACATTGTTATGTGGACAGTGTGGAGCTGCTTTAAAGGACTTCGAATCATTCAGGGAACACTTAGCTAGACATCTTCAAGCTGATCATAGAAATGATGTTAGACACCCTTGTTTAAAGTGTGAAGCCACTTTTCAAGATAGGGAAGACATGTTGGTACATTTAACGAAACATTATTTGGGCCAGATTAGTAAAGAATATGCTTGTGGTGCATGTAAGAAACTTTATCCTCATCCTGATCTTCTTCAGAGGCATTTACTCGACAGTCATGCTCATCATCTCTATCGATGCGCCTTGTGCAGAGATACATTTGATTCTAGAGTAGCGATACAGGTTCATTTTGCTGTGAAACACAGTCAAGAATGCAGAATCTATAGATGCAATGCTTGCACAGTgtctaataatgaaaattcaccgGGAAATGCGccagaagaaggaaaaagctTCTTCCGAAGTGAGTCTGAAATGGCAAACCATGTAAGAAATGTCCACGCACCTCCAACGATGTCAAATAATAGTCCTGTGGCCAGGAGTCCTGCTTCCACTCCAGGAATAACTGGGAATTCCGGACCAAGATGCGTCTTCTGTGGAATCTGTTGTAGTTCCGAGCTGGAACTACAACTCCATTTAGCCAGCCATTCTGCTAACTTATATAGATGTCCTGTTTGTAGAGAAGGATTTgccgtggaatttttattagatagaCATATTACTCAAGCACATCACTCTAGTGATCATCAGGATGTCATGAGAAGTAATTCTAGAGAGAATGGAAGAATTGGTAGACTACCAAGATTACAGGAAgagGCTAAATCCCAAAAAAGAGGTCGCTCTCCAGCTTCCAGCAACAACAATTCTCTGAATCAACGTGACAACAACAATAAACGTCCAAATTACACCAATGCATCCTCTCAACAATGCGATCTCTGCGAAAGAGGAGAGTTTTCCAACGAAGCAGAACTTCAAGCTCACAAAAAATTGGTTCACACTCCGACCAAGTTTCAAAATAAGTCTATATCAAGTCTTAGCATGACTTGTGCATACTGTGGAGAAGTATGTCGTTCTAGAACTGACCTAGAATCTCATACAAGGATCCAACATGCATCAAGTGAACCTGGAGGACGCCACAAGTGTAATATTTGTGACGAAGTGTGTCCATCAGGAGCAACACTTGCAGAACATAAACTTCAGAAACATTGTAAGATTCAATTAAGTGACACATGTATCGTTTGTCGAGGAAACCTATCTTCAGAATCACAGTTTCTAGAACATGTGCAAAGACACAGTCTGGAGAATGTGGATCCTCAGCAGAGATTAGATGGTTCTCTTCCTCATCTTCCTGCAGCTTGTGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAATGTCGTCTCCATGCCAGACACCACTTAAGAACTTCTGGTTCTCACAGCGTGGCATCCAGCCCCAGTCCCAATCAAAAGAATCAGAGTCCAAGTTGTTGTCTTTGTTTAAGAGATTATTCAGCTGATGACTTTGTTAATTTACCTCCAAGTAATATAAGTGGAGGAGGACAGTCTTTAAGAGTTTGCAAATCTTGTTACATTCGACACTCTCAGGGTCTACCTATTTTGAATTCACCTTACGAGCCTATTAAATGTGATGCTTCTTGGACATCCAGTAATAAAGATGGGCAATGGGATAAATCAAAGGATAAATGGGAAACCGAGaataaagaagataaaaatgagGGGAATGATAGAAAGAAGTGTCAAGATTGTGGGGTGAAATTTGAGGATTCTGACAAGGTGGAGAAACATAGGATAGTCGAACATGAAAAAGTTATAAGTGGAGTTATGTTAAACACATACACATGTATACAGTGTCAGatgTCGTTCCCAACAGAGGCAAAGATTCAGCAACATGTAAGAAAAGAACATCTAGAAACATCGGGAAGGACTTCCATAGAAACATTACGATGTCATCTGTGTCTTTTTGAAGCTAGCAGTCCATTAGAATTGCAGAGTCATTTGATAGAGCATACTTTCGCAGGATGTGCCGCTCTCAGCTGTTACATTTGTCAATCTCTCTTCACCGCACCTACTGGTCTTCAGAATCATATGCTTCAAGAACACGGTCTGGGTGCTCGTCCCTACGATTGTTCCCAATGTACACTCAAGTTCTTCTTCAGAGCAGAACTAGATCATCATATGTTAACATTTCATCGACCGGGAGACGTGCCACCACCCAGTAAAAATACACAGAATAccatcgaaataaaaaaaaaagataccgaagaaagaaattgcaatgAAGGAGTGACTGTAAAAGAGGAAATGGTTCCAGGAACaactgaagaagaagaagaaatcaaCGTGGATGAACAAATAGAAGAGGATGGTCAAAAAGCAGATCAACAATCAGAAATCgagacaaaattaaaaactgagCTCGAGGAAGAATTTATTCCTGAAAAAATGGAATCGTGA
Protein Sequence: ALGTGSSSWQSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGTNATAPYPCQFCDRTFPRLSYLKKHEQNHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTTCSRGYNTAAALTSHMQSHKKHHQSQTSKLQDVDYGRRSVSSHSTSSPPIPSSPSPSLNIVLNSKTCMKSTQGSASTTPILSSPLKLACMYCTRDTFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRINEQISYQNEKTFDRKPEGSSKEHKRKYQDDSEKSIEKDHYENAFTCSQCTMKFSTLGSLRDHLVSIHRTDGFGSALMMCPLCGIPCTSAATYAEHYVLQHCENRRTGLLEIRDYTDSKMNGNYDTKSNRSQKCREQTSSEPADLTNKHSTSTESNYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNDVRHPCLKCEATFQDREDMLVHLTKHYLGQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTVSNNENSPGNAPEEGKSFFRSESEMANHVRNVHAPPTMSNNSPVARSPASTPGITGNSGPRCVFCGICCSSELELQLHLASHSANLYRCPVCREGFAVEFLLDRHITQAHHSSDHQDVMRSNSRENGRIGRLPRLQEEAKSQKRGRSPASSNNNSLNQRDNNNKRPNYTNASSQQCDLCERGEFSNEAELQAHKKLVHTPTKFQNKSISSLSMTCAYCGEVCRSRTDLESHTRIQHASSEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLSSESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRTSGSHSVASSPSPNQKNQSPSCCLCLRDYSADDFVNLPPSNISGGGQSLRVCKSCYIRHSQGLPILNSPYEPIKCDASWTSSNKDGQWDKSKDKWETENKEDKNEGNDRKKCQDCGVKFEDSDKVEKHRIVEHEKVISGVMLNTYTCIQCQMSFPTEAKIQQHVRKEHLETSGRTSIETLRCHLCLFEASSPLELQSHLIEHTFAGCAALSCYICQSLFTAPTGLQNHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRPGDVPPPSKNTQNTIEIKKKDTEERNCNEGVTVKEEMVPGTTEEEEEINVDEQIEEDGQKADQQSEIETKLKTELEEEFIPEKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_01420489;
80% Identity: -