Basic Information

Insect: Bombus vosnesenskii
Gene Symbol: znf423
Assembly: GCA_011952255.1
Location: NW:4363233-4502063[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 6.4e-06 0.00041 19.9 1.8 1 23 145 167 145 167 0.98

2 18 0.19 12 5.9 4.1 1 23 198 220 198 220 0.98

3 18 2.3e-07 1.5e-05 24.5 4.3 1 23 226 248 226 248 0.99

4 18 0.00017 0.011 15.5 0.2 1 23 254 276 254 276 0.99

5 18 5.8e-05 0.0037 16.9 0.8 1 23 428 451 428 451 0.96

6 18 0.32 20 5.1 0.0 2 23 462 484 461 484 0.88

7 18 1.1 72 3.4 0.3 3 23 547 567 545 567 0.95

8 18 0.0016 0.1 12.4 0.6 1 23 579 601 579 601 0.97

9 18 0.011 0.69 9.8 0.3 1 23 610 633 610 633 0.92

10 18 2.8 1.8e+02 2.2 0.2 1 23 638 661 638 661 0.91

11 18 0.17 11 6.0 0.8 2 23 735 756 735 756 0.96

12 18 0.0039 0.25 11.1 0.1 1 23 761 784 761 785 0.94

13 18 0.91 59 3.7 0.1 2 23 849 872 848 872 0.83

14 18 0.00018 0.012 15.4 1.0 2 23 888 910 887 910 0.96

15 18 0.031 2 8.3 1.0 1 23 919 942 919 942 0.93

16 18 0.94 61 3.7 0.4 2 23 1155 1176 1154 1176 0.94

17 18 0.52 34 4.5 0.1 2 23 1185 1207 1184 1207 0.93

18 18 0.017 1.1 9.1 3.1 1 23 1214 1237 1214 1237 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	6.4e-06	0.00041	19.9	1.8	1	23	145	167	145	167	0.98
2	18	0.19	12	5.9	4.1	1	23	198	220	198	220	0.98
3	18	2.3e-07	1.5e-05	24.5	4.3	1	23	226	248	226	248	0.99
4	18	0.00017	0.011	15.5	0.2	1	23	254	276	254	276	0.99
5	18	5.8e-05	0.0037	16.9	0.8	1	23	428	451	428	451	0.96
6	18	0.32	20	5.1	0.0	2	23	462	484	461	484	0.88
7	18	1.1	72	3.4	0.3	3	23	547	567	545	567	0.95
8	18	0.0016	0.1	12.4	0.6	1	23	579	601	579	601	0.97
9	18	0.011	0.69	9.8	0.3	1	23	610	633	610	633	0.92
10	18	2.8	1.8e+02	2.2	0.2	1	23	638	661	638	661	0.91
11	18	0.17	11	6.0	0.8	2	23	735	756	735	756	0.96
12	18	0.0039	0.25	11.1	0.1	1	23	761	784	761	785	0.94
13	18	0.91	59	3.7	0.1	2	23	849	872	848	872	0.83
14	18	0.00018	0.012	15.4	1.0	2	23	888	910	887	910	0.96
15	18	0.031	2	8.3	1.0	1	23	919	942	919	942	0.93
16	18	0.94	61	3.7	0.4	2	23	1155	1176	1154	1176	0.94
17	18	0.52	34	4.5	0.1	2	23	1185	1207	1184	1207	0.93
18	18	0.017	1.1	9.1	3.1	1	23	1214	1237	1214	1237	0.97

Sequence Information

Coding Sequence: ATGTCCAGGAGGAAGCAGGCAAAGCCTCGATCTCTAAAACGAGACGAAGAGTGGGACGACGGGAACGAGCAAAATGTCCTGGAGGTAACCGAGCAGGATAATGAGACAACGGGAATTAAACAGGATgacgaggaggaagaggaagaagaggagcTGCAGAGAGCGTTCAGTCAACATTCGGAGGAGTACGCACAAGAAGGAAGGCCATCGTCAGTTCAAGGACTAGATCTGGAGAATCAGAACAGCCTCGACAGCGAGGCCTTGGGCACCGGAAGTTCGTCATGGCAGAGCGAGGATGGCGGTGCAAACTCGCGACGTGGCGGAGAGACGCCGTCTTCTTGTGCGACGCCGACATCGGCGAGCTTCCCGTCGGAGCCCGAGGTCGACGCCGACGTTGGTGTCAACGCCGACGGAACCAACGCTACCGCACCTTATCCTTGTCAATTCTGTGACCGCACATTTCCTCGACTTAGCTACCTGAAGAAGCACGAACAGCGTCACTTTGATCAACTTCATCGAGGATTGATATTAGCTCTTCACGGTTCGATGTCCAGTGTAATTTCTATTCTGAGCCACGGAGATCAAATGCCATACAAATGCAACTGGTGTGCCAGATTGTTCAAACATAAACGCAGTAGAGATCGACACGTGAAACTTCATACAGGAGACCGAAGATATCGATGCACGCACTGCGACGCTGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACTCACGACACCCAGAAGCCGTATCAGTGCACAGCATGCTCCAGAGGCTACAACACGGCAGCCGCTCTAACATCTCACATGCAGTCTCACAAGAAACAATCCCAAGGAACTGCCAGGCTTCAAGACATTGATTATGGTAGAAGAAGCGTGTCTTCTCATAGTACATCATCTCCGCCAGTACCAAGCTCCCCATCGCCATCTTTAAACCTTTTGTTGAATCCAAAGGCTGGCTTAAAAAGTTCCCAAGGAAGTGCTTCGACGACTCCAATTTTGAGTTCACCGTTAAAATTAGCCTGCATGTACTGTACCAGAGATTCCTTTAGTTGCATGCAACAGCTGCAAATGCACGTGCATACTATGCATCAGGCTATCCTTAGTGGAGAAACTGTTGCAGTATCCCCATCAACAAATAGAACCAACGAACAGATGAGTTATCAACGTGAGAAAACCCTGGATAGACCAGAAGGATCATCCAAAGAACAGGAAAGAAAGTATCAGGATGATTCAGAGAGATCTATAGAGAAAGATCACTatgaaaatacatttacaTGCAATCAGTGTACTATGAAGTTCTCTACGTTAGACTCTTTGAGAGATCATCTGATCTCAATTCATAGAACCGATGGTTTTAGTTCTACTTTAATGATGTGCCCTCTCTGCGGCATTCCTTGTGCTTCTGCAGCAGCCTACGCGGAGCATTATGTCCTCCAACATTGTGAGAATCGAAGAGTAGATCCATTGGAGGTTAAAAGTTATATAGATTCCAAAATGAATGGAAGCAACGAAACTAAGAGTCCCAGGAATCAGAAATATAGAGAGCAAACTTCTTCTGAGCCAGCTGATTTGACCAACAAGCATTCCACCAGTACAGTCAGCAATTATACAGCTGGTACGCTATTTTGTGGACAATGTAGAGCTGCACTGAAAGACTTCGAGTCATTCAGAGAACACCTAGCTAGACATCTTCAGGCTGATCATAGAAATGACGTTATTAGACATCCTTGTCCAAAGTGTGAAGCCACTTTTCAAGATAGGGAGAACATGTTGGTACACTTGACAAAGCATTATTTGAGTCAGATTAGTAAAGAATATGCTTGCGGTGCTTGCAAGAAGCTGTATCCCCATCCGGACCTCCTCCAAAGACATTTACTTGACAGCCATGCTCATCATCTCTATAGATGCGCCCTGTGCAGAGACACTTTCGATTCTAGAGTGGCAATACAGGTCCATTTCGCTGTAAAACACAGTCAAGAATGCAGTATTTATAGGTGCAATGCTTGCACAGTGtctaataatgaaaattcacCAGGAAATGCGCCAGGCGAGGGTAAAAGCTTCTTCAGAAGCGAATCCGAAATGGCAAGCCATGTGAGAAATGTTCATGCACCTCCTACAGTTTCTAACAACAATCCTGTCGTTACAAGCCCGGCCTCCACTCCGGGAATAACTGGAAATTCAGGACCAAGATGCGTTTTCTGTGGAACTTACTGCAGTTCTGAGCTGGAACTACAGCTCCACTTGGCTAGCCACTCTGCTAATTTATACAGGTGCCCAATTTGTAGAGAGGGATTTGCTGTGGAGTTTTTACTAGACAGGCATATTGCTCAAGTGCATCATTCTAGTGATCATCAAGGTGCTATAAGGAATAATTCTCGGGAGAATGGAAGGATTGATAGACTACCCAGATTACAGGAAGAAGGCAAATCTCAAAAGAGAGGCCGCTCTCCAGCCTCCAGTAACAACAATTCTCTGAACCAGCGcgataacaataataaacGTCCACATTACTCAAATCCATCTGCTCAGCAGTGTGATCTCTGTGAAAGGGGAGAGTTTTCCAACGAGGCCGAACTGCAAGCCCACAAGAAACTTGCTCACACTCCATCCAAGCTTCCAAACAAGTCCATATCGAATCTCAGCATGTCTTGCGCATATTGCGGGGAAGTATGCCGTTCTAGAACTGACCTGGAGTCCCACACAAGGATTCAACATGCATCGAATGAACCTGGTGGTCGGCACAAGTGTAACATATGCGACGAAGTCTGTCCATCAGGGGCAACTCTTGCAGAACATAAATTGCAGAAACACTGCAAGATTCAATTAAGCGACACATGCATCGTTTGTCGAGGAAATCTAGCTTCGGAGTCACAGTTTCTGGAACATGTGCAAAGACATAGCCTAGAGAACGTGGATCCTCAGCAAAGATTAGATGGTTCTCTTCCCCATCTCCCTGCAGCTTGTGTAGTTTGTAGACAGACATTGATCAGTGATTTGGAGTGTCGTCTTCACGCCAGACACCACTTAAGAGCTTCTACTGGTTCTCACAGTGTAACATCCAGCCCCAGCCCCAATCAAAAGAACCAGAATCCCAGCTGTTGCCTTTGTTTAAGAGATTATTTAGCTGATGACTTTGTCAATTTGCCTCCAAGTCATATAAGCGGTGGAGGACAGTCTTTAAGGGTCTGCAAGTCATGCTACATTCGTCACTCTCAGGGTTTACCTATCTTGAATTCACCTTATGAGCCTGCTAGATCTAAATGTGACGGTACTTGGACATCCAATAACAAAGATGGACAATGGGATGGATCAAGGGATACATGGGAGTCAGAGAACAGATTTAAGGAAGACAGAAACGAGATGTCGTTGCCaacagaaacaaaaattcaacAGCATATAAAGAAGGAACAGCTGGAGATGTCGGGAAAGACTTCCATAGAGGCGTTACGATGTCATCTGTGTCTTTTTGAAGCTAGCAGTCCCTTACAATTGCAAAGCCATTTGATAGAGCACACTTTTGCAGGATGTGCCGCTCTCAGCTGTTACATTTGTCAGTCTCTCTTCACAGCTCCTATCGGCCTCCAGaGCCATATGCTTCAAGAGCATGGCCTGGGTGCTCGTCCCTACGATTGTTCTCAGTGCACGCTCAAGTTCTTCTTCAGAGCAGAATTGGACCATCACATGCTAACATTTCATCGACCTGGGGATGCGTGTTCACCGGATGACAAGGCAGAAAATACTGGAGAAACGAAAGCAAGAGACGCTGAGGAAAGAAACTGCGGTGAAGAAATAACCGTAAAGGAAGAAATAGTTTCAGAAATAGTTgcagacgaagaagaagaaatcaaCGTGGACGAACAAGTGGAAGAGAGCGATCAAAAGGCGAACAAGGAAACAGAAATTGAGACGAAATTGAAAACTGAACTTGTGGAGGAATCTGTTCCAGAAAAGATGAAATCGTGA
Protein Sequence: MSRRKQAKPRSLKRDEEWDDGNEQNVLEVTEQDNETTGIKQDDEEEEEEEELQRAFSQHSEEYAQEGRPSSVQGLDLENQNSLDSEALGTGSSSWQSEDGGANSRRGGETPSSCATPTSASFPSEPEVDADVGVNADGTNATAPYPCQFCDRTFPRLSYLKKHEQRHFDQLHRGLILALHGSMSSVISILSHGDQMPYKCNWCARLFKHKRSRDRHVKLHTGDRRYRCTHCDAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKQSQGTARLQDIDYGRRSVSSHSTSSPPVPSSPSPSLNLLLNPKAGLKSSQGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGETVAVSPSTNRTNEQMSYQREKTLDRPEGSSKEQERKYQDDSERSIEKDHYENTFTCNQCTMKFSTLDSLRDHLISIHRTDGFSSTLMMCPLCGIPCASAAAYAEHYVLQHCENRRVDPLEVKSYIDSKMNGSNETKSPRNQKYREQTSSEPADLTNKHSTSTVSNYTAGTLFCGQCRAALKDFESFREHLARHLQADHRNDVIRHPCPKCEATFQDRENMLVHLTKHYLSQISKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECSIYRCNACTVSNNENSPGNAPGEGKSFFRSESEMASHVRNVHAPPTVSNNNPVVTSPASTPGITGNSGPRCVFCGTYCSSELELQLHLASHSANLYRCPICREGFAVEFLLDRHIAQVHHSSDHQGAIRNNSRENGRIDRLPRLQEEGKSQKRGRSPASSNNNSLNQRDNNNKRPHYSNPSAQQCDLCERGEFSNEAELQAHKKLAHTPSKLPNKSISNLSMSCAYCGEVCRSRTDLESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDTCIVCRGNLASESQFLEHVQRHSLENVDPQQRLDGSLPHLPAACVVCRQTLISDLECRLHARHHLRASTGSHSVTSSPSPNQKNQNPSCCLCLRDYLADDFVNLPPSHISGGGQSLRVCKSCYIRHSQGLPILNSPYEPARSKCDGTWTSNNKDGQWDGSRDTWESENRFKEDRNEMSLPTETKIQQHIKKEQLEMSGKTSIEALRCHLCLFEASSPLQLQSHLIEHTFAGCAALSCYICQSLFTAPIGLQSHMLQEHGLGARPYDCSQCTLKFFFRAELDHHMLTFHRPGDACSPDDKAENTGETKARDAEERNCGEEITVKEEIVSEIVADEEEEINVDEQVEESDQKANKETEIETKLKTELVEESVPEKMKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684951;
90% Identity: iTF_00232173;
80% Identity: -