Dpse008366.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pseudotakahashii
Gene Symbol
-
Assembly
GCA_035046095.1
Location
JAWNOE010000121.1:2755656-2758684[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 8.1e-05 0.0068 17.1 0.7 2 23 206 228 205 228 0.94
2 17 0.00055 0.046 14.5 0.2 1 23 235 257 235 257 0.97
3 17 0.22 19 6.3 0.1 2 23 289 310 288 310 0.94
4 17 8.6e-05 0.0072 17.0 2.2 1 23 400 423 400 423 0.97
5 17 0.26 22 6.1 0.6 1 19 430 448 430 451 0.93
6 17 0.071 6 7.8 6.4 1 23 460 482 460 482 0.95
7 17 7.3e-06 0.00062 20.4 0.4 1 23 489 512 489 512 0.97
8 17 0.00041 0.035 14.9 2.4 2 23 520 541 519 541 0.96
9 17 0.019 1.6 9.6 0.1 2 21 568 587 567 588 0.94
10 17 0.0085 0.72 10.7 2.6 1 23 637 660 637 660 0.98
11 17 0.035 3 8.8 0.4 1 23 697 720 697 720 0.93
12 17 0.00013 0.011 16.4 1.6 2 23 748 770 747 770 0.95
13 17 0.0004 0.033 14.9 0.1 1 23 784 806 784 806 0.95
14 17 1.9e-05 0.0016 19.1 1.0 1 23 812 834 812 834 0.99
15 17 3.5e-07 2.9e-05 24.6 2.6 1 23 840 862 840 862 0.98
16 17 3.9e-05 0.0033 18.1 3.8 1 23 868 890 868 890 0.97
17 17 2.7e-05 0.0023 18.6 0.5 1 22 896 917 896 920 0.90

Sequence Information

Coding Sequence
ATGAAGCTGCCGGTGATTTGTCGCACCTGCGACTCCACGGACACCGATAACCTGCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGCTGCTCTCCGAGATTCTCTGCGAGCTAACCGAAATCAATCTGGATGCCACTGGAAGCCAGAAACTGCCGCAGTGCCTGTGCAGCGGATGCACCAAGAAGCTAATGGTTGCCTATTGCTATGTGAAGCAGGCGCTGGTCGCCAACGAACTGCTAATGAAGCACCTGAGGAACGGAGCTGCCCCAACGACCACCGACTGCCTGCAGGAAGCGCCCATGGAACTGTGTGCCGAGCAGCATGTGGAGGTCAAGCTAGAGACGGAGGACGAGGAAGGTGGCGACAACGATTTTAGCATAACTTGCTCCGAACTGCCGGAACCGGATGAAATGGATGTGGAGAGCAAGAAGTCAGTGGATCCGCTAACCATGATTGAGACGGTGAAGCTGGAATCGGAACTGAGGAGCGTGCAGAAGCCGTCGGAAGATGAAGCTGCCTCGGACTTTGACGACGAAGACTCCCTGGACAACCTGCCGCTGGACAAGCGCATTCAACAGTGGAAGACCGGGAGGAAGTCGTCTGTACTCAAATGCCAGGACTGCCCGAGGAGCTTTAAAAGAGTCGAGTTCTTGAAACGCCATGAAATCCGCGTACACAAGCAGGATACCCGCTCATTTGCCTGCTCCCTGTGCATTCGGAAGTTCAGCCGCAGCGAAGCTTTAGAAGCGCACTTGAAGGTCCATCGGAACTCCAAGCGATCGGCCAACATAAGCGAGCACAAGAAGGCAAAGGCGGTGGATCTCAATCTCTGCAAACCGCACGGCTACAAACTAATCGAGTGCATGATCTGCCAGAGCCAGTACAACAAGATTGCCGATCTGCGACGGCACTTGGAGGAGCATCCCGAGATAGTAAACCTGTGCGGGCGGCCAAATGTGGAGCCCCATGAGTTGGCTGAGCTGTTTTACCCCGACTCCAAAGACCTGGGTGAGGATCAGTTGATTAGCCTGATTCGCAAGGATCTGGCGGCGGGCATTTATCAGCGTTTCTATTCGATAACCAACCAAAGTGGATACGAAATGGACCTGGACAGTTCGGAGACGGACAGCGATCTGGACGGAGATCCGGAGGATCAACAAAAAAAGCGAAAGAAGTGGCGCAAGGCCAGCTACAGCTGCGAGCTGTGCCAGCAGAAGTTCCCGCGGAAATACCAGCTTTACGACCACCAGCGACAGACGCACAGTTGGTCAGATGCTCCTCATGTCTGCGGGCGTTGCGATGGACGCTTTGTGAGCCTACAGTTGCTGCGGCACCACAACGAATCGCAGTGCAGGAATGCACAGAAACGTTTCCTCTGCCACAAATGCCCGCTCCGTTTCCGCTGGAAACACAACCTTAAAACTCACTTCCGCGAGCACAGGATTACAAATCAGACTTTTGAGTGTCCCGAATGCAAGAGGGTTTTTGACAAGAAGAAATCCCTCACCGTTCACCTGCTCAGCGTGCATGCTGAGGAATCGAAATTGATACCCTGCCAGTGGTGCAGTCGGAAATTCTACCGACATGACTACCTGGTGAAGCACCTGAAGCGACACGGACTTAAGGAGCAGGACATTCCACTGGCCGAAACCTTAATTGCGGCAACCTCGCGGCCCAACGGAGCGAAGCGCATCACCTGTCGCATGTGCAACCTGCATTTCGAGCGTATCGTCGATTTGCGAGCCCACATTCAGCTGGAGCTGAAGCTGTCTTTGTCGCTGCACCAAAGCTACGATTCCCTGCACAACTACTCGATAACAAACGAGTCCGGGTTCGAGTTGCAGCTGGAGGATTCGGAGACCGAGGACGAAATGCAACCAACTGGTGGCAGTCGACCCGTTTACATCTGCGAACTGTGCAGTGTGCAATGCAAGCGGAAATTCGAAATGATCCAGCATCAGCGGACGATGCATCGTTTCGACAAAATGCCACACGAGTGCGATGACTGCATTTTCAAGTGTGTCTCCAAGAGCATCATGGATCATCACCGGCTGGGCCAGTGTAGCAGTACAGAAAAGAAGCATCCTTGCGACAAGTGCTCCTACAAGTTCATGTGGCCCGAGAATCTGGAGCAACATATTATTCTGCAGCACAGCAAATCTTCCGGCGTCAAACGAACGTCTGGTGGCGGCGACCTGGACAAGGATGCCGCCGAGGACGGGGTCCCGCTGCTGCAGTGTCCGCACTGCGATCGCACCTACCAGATGAAGTCGCGCCTAAACAACCATATCCGCGATGTGCACGTCAACGGTGACCGCAAGCGCAAGGAGGCGATCAAGCGCTTCCTCTGCTCCCTGTGCGGCATGGAGACGAGATCCGCCGCGGCTCTGGTGACCCATATGCGTCGGCACACGGGCGAGAAGCCCTTCAAGTGCGATCTGTGCGAGATGGCCTTTCCCCGGCACTCGGAGCTCGCCTCGCATCGCCGAATGCACACCGGCGAAAAGCCATTCCACTGCACCGTTTGTGGCAAGGATTTTGCTCGATCCGACAAGCTCAAGCGTCATATGCTCACCCACAGCGGCTTAAAGCCGCACAAGTGCACCTACTGCGAGAAGAGCTACCGCCAGGCGAAGGATCTGAAGCTCCACCTGCAGCAGCACACCGGCGAGTGTCCCTTTGTGTGCGGCACCTGCGGCGAGCGCTTCATCCAGAGCAGCACGCTCGAGAAGCACCGGCTGATGCGACGCCACTTTGACGAGGTGGAAGCGTGGCTAAGGCGCCAGAAATAG
Protein Sequence
MKLPVICRTCDSTDTDNLLKLATPSKKYPDKLLSEILCELTEINLDATGSQKLPQCLCSGCTKKLMVAYCYVKQALVANELLMKHLRNGAAPTTTDCLQEAPMELCAEQHVEVKLETEDEEGGDNDFSITCSELPEPDEMDVESKKSVDPLTMIETVKLESELRSVQKPSEDEAASDFDDEDSLDNLPLDKRIQQWKTGRKSSVLKCQDCPRSFKRVEFLKRHEIRVHKQDTRSFACSLCIRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPEIVNLCGRPNVEPHELAELFYPDSKDLGEDQLISLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDPEDQQKKRKKWRKASYSCELCQQKFPRKYQLYDHQRQTHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGAKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSLHNYSITNESGFELQLEDSETEDEMQPTGGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSTEKKHPCDKCSYKFMWPENLEQHIILQHSKSSGVKRTSGGGDLDKDAAEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK