Basic Information

Insect: Drosophila serrata
Gene Symbol: -
Assembly: GCA_002093755.1
Location: NW:2559796-2563128[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.4e-06 9.4e-05 22.4 2.8 1 23 206 229 206 229 0.95

2 17 3.4e-05 0.0022 18.1 0.2 1 23 236 258 236 258 0.97

3 17 0.19 12 6.3 0.1 2 23 290 311 289 311 0.94

4 17 3.3e-05 0.0021 18.1 1.8 1 23 402 425 402 425 0.97

5 17 0.22 14 6.0 0.6 1 19 432 450 432 453 0.93

6 17 0.061 3.9 7.8 6.4 1 23 462 484 462 484 0.95

7 17 6.2e-06 0.0004 20.4 0.4 1 23 491 514 491 514 0.97

8 17 0.00035 0.023 14.9 2.4 2 23 522 543 521 543 0.96

9 17 0.016 1 9.6 0.1 2 21 570 589 569 590 0.94

10 17 0.0072 0.47 10.7 2.6 1 23 639 662 639 662 0.98

11 17 0.055 3.5 8.0 0.5 1 23 699 722 699 722 0.95

12 17 0.00011 0.0074 16.4 1.6 2 23 760 782 759 782 0.95

13 17 0.0025 0.16 12.2 0.1 1 23 796 818 796 818 0.95

14 17 1.6e-05 0.0011 19.0 1.0 1 23 824 846 824 846 0.99

15 17 2.9e-07 1.9e-05 24.5 2.6 1 23 852 874 852 874 0.98

16 17 3.3e-05 0.0021 18.1 3.8 1 23 880 902 880 902 0.97

17 17 2.3e-05 0.0015 18.6 0.5 1 22 908 929 908 932 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.4e-06	9.4e-05	22.4	2.8	1	23	206	229	206	229	0.95
2	17	3.4e-05	0.0022	18.1	0.2	1	23	236	258	236	258	0.97
3	17	0.19	12	6.3	0.1	2	23	290	311	289	311	0.94
4	17	3.3e-05	0.0021	18.1	1.8	1	23	402	425	402	425	0.97
5	17	0.22	14	6.0	0.6	1	19	432	450	432	453	0.93
6	17	0.061	3.9	7.8	6.4	1	23	462	484	462	484	0.95
7	17	6.2e-06	0.0004	20.4	0.4	1	23	491	514	491	514	0.97
8	17	0.00035	0.023	14.9	2.4	2	23	522	543	521	543	0.96
9	17	0.016	1	9.6	0.1	2	21	570	589	569	590	0.94
10	17	0.0072	0.47	10.7	2.6	1	23	639	662	639	662	0.98
11	17	0.055	3.5	8.0	0.5	1	23	699	722	699	722	0.95
12	17	0.00011	0.0074	16.4	1.6	2	23	760	782	759	782	0.95
13	17	0.0025	0.16	12.2	0.1	1	23	796	818	796	818	0.95
14	17	1.6e-05	0.0011	19.0	1.0	1	23	824	846	824	846	0.99
15	17	2.9e-07	1.9e-05	24.5	2.6	1	23	852	874	852	874	0.98
16	17	3.3e-05	0.0021	18.1	3.8	1	23	880	902	880	902	0.97
17	17	2.3e-05	0.0015	18.6	0.5	1	22	908	929	908	932	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTAATGTGTCGCACCTGCGACTCCACGGACACCGACAATCTTCTAAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGCTGCTCTCGGAGATTTTGATGGAGCTCACCGACATCCATGTGGACGCGAGTGGCAGTCAGAAGTTGCCGCAATGTTtgtgcagcagctgcagcaagAAACTAGTGGCAAGTTATTGTTTCGTCAAGCAGGCGCTGGTCGCCAACGAACTGCTGATGAAGCACTTGAAGAGCAGCTCAGCGCCGACCGCCACCGACTGTCTGCAGGAGGCGCCTATGGAGCTGTGCGCCGAGCAGCATGTAGAGGTTAAGATGGAGACGGAAGACGAGGAGTGTGGCGACAACGATGTTAATATCACCTGCTCCGAGCTGCCAGAAACGGGCGAACGGAATGTGGAGAGCAAGAAATCCGTGGATCCACTGACCATGATTGAGACAGTGAAACTGGAGGGGGAACCGCTAAGCGTGGAAAGGCCGGCTGAAGAAGAGCCCACCTCGGACtttgacgatgacgatgaagACTCCCTGGACAACCTGCCTCTGAATAAGCGCATTCAAAAGTGGAAGGCTCGAAGTATGTCCGTTTTCAAGTGCCACGATTGCCCGAGAAGTTTCAAGAGTAACGAGTACCTAAAGCGCCATGAAATCCGAGTCCACCAGCCGGAGACCCAATGGTTCGCCTGCTCCCTCTGCGTTCGCAAGTTCAGCCGCAGCGAAGCTCTTGAGGCTCACCTGAAGGTCCACAGGAACTCCAAGCGATCGGCCAACATCAGCGAGCACAAGAAGGCCAAGGCGGTGGACCTGAATCTCTGCAAGCCGCACGGCTACAAGCTTATCGAGTGCATGATCTGTCAGAGTCAGTACAACAAGATTGCGGATCTGCGGCGACACTTGGAAGAGCACCCGGATATTGTCAGTCTGGGCGTTCGTCCAAATGTGGAGCCCAATGAGCTGGCTGAACTGTTCTATCCCGACTCCAAGGACATGGATGAGGACCAATTGATTGGCCTAATCCGCAAGGATTTGGCGTCGGGCATTTATCAGCGTTTCTACTCGATAACCAATCAGAGTGGCTACGAAATGGATCTGGATAGCTCGGAGACGGACAGCGATATGGATGGTGAACCTGAGGATCCGCAGAACAGGAGGCGACGCAAAAATCGCAAGTGCAGCTACACCTGCGAACTATGTCAGGAGAAGTTTCCGCGGAAATATCAGCTCTATGACCACCAACGGCAGAGCCACAGTTGGTCCGACGCTCCACATGTCTGCGGGCGGTGTGATGGACGCTTCGTTAGcctgcagctgctgcggcATCACAACGAGTCGCAGTGCCGGAATGCACAGAAGCGCTTTCTTTGCCACAAATGCCCTTTGCGCTTCCGGTGGAAACACAATCTGAAGACCCATTTCCGCGAGCATAGGATTACAAATCAGACCTTCGAGTGTCCCGAGTGTAAGCGGGTCTTTGACAAAAAGAAATCCCTCACCGTTCACCTGCTCAGCGTTCATGCCGAGGAATCAAAGCTCATACCCTGTCAGTGGTGTAGCCGCAAGTTCTACCGACATGATTACCTGGTGAAGCATTTGAAGCGTCATGGACTTAAGGAGCAGGACATTCCACTGGCCGAAACCTTAATAGCGGCCACTTCGCGGCCAAATGGAACAAAGAGAATCACCTGCCGGATGTGCAATCTACACTTTGAGCGGATTGTGGATCTGCGGGCTCATATCCAGCTGGAGCTGAAGCTCTCTTTGTCCCTCCATCAGAGCTACGACTCTCCGCATAATTACTCGATCACAAACGAGTCTGGATTCGAGTTGCAGTTGGAGGATTCGGAGACTGAGGACGAGATGCAGTCGAGCGGCGGCAGTCGCCACGTTTACATCTGCGAGCTGTGTAGTGTGCAGTGTAAGCGGAAATTTGAGATGATCCAACATCAGAGGACAATGCATCGATTTGACAAAATGCCACATGAATGCGATGACTGCATCTTTAAGTGTGTGTCCAAGAGCATCATGGATCACCATCGGCTGGGGCAGTGCAGCAGCAAGGAGAAGATGTACACCTGTAGCAAGTGCTCCTACAAGTTCATGTGGCCCGAGAATCTGGATCTGCACGTGCGACTGCAGCACAGCGAATCCTCCTCCCACAGCAGTCCCACAGGCGTTAGCGGTGGTGGCAGGCCACGTACTGGACCGGGTGAACTGGATAAGGACGCCGGTGAAGATGGGGTACCATTATTGCAGTGTCCGCATTGCGATCGCACCTACCAGATGAAGTCCCGCCTCAACAACCACATCCGCGATGTGCATGTAAACGGTGATCGGAAACGCAAGGAGGCAATCAAGCGTTTTCTGTGCTCCCTGTGCGGCATGGAGACCCGATCGGCGGCCGCTCTTGTTACACACACCCGGCGTCACACCGGTGAGAAGCCCTTCAAGTGCGATCTGTGCGAGATGGCCTTTCCCAGGCATTCAGAGTTGGCCTCTCATCGCCGAATGCACACCGGGGAGAAACCATTCCATTGCACAGTCTGCGGCAAGGATTTCGCCCGCTCTGACAAGCTCAAGCGCCACATGCTCACCCACAGCGGTCTGAAGCCGCACAAATGTACGTACTGCGAGAAGAGCTATCGCCAGGCGAAGGATTTGAAGCTCCACCTGCAGCAGCACACCGGTGAATGTCCATTTGTGTGTGGCACCTGCGGCGAGCGATTTATACAGAGCAGCACGCTGGAGAAACACCGTCTGATGCGTCGTCACTTTGACGAAGTGGAAGCCTGGCTAAGGCGTCAAAAATAA
Protein Sequence: MKLPVMCRTCDSTDTDNLLKLATPSKKYPDKLLSEILMELTDIHVDASGSQKLPQCLCSSCSKKLVASYCFVKQALVANELLMKHLKSSSAPTATDCLQEAPMELCAEQHVEVKMETEDEECGDNDVNITCSELPETGERNVESKKSVDPLTMIETVKLEGEPLSVERPAEEEPTSDFDDDDEDSLDNLPLNKRIQKWKARSMSVFKCHDCPRSFKSNEYLKRHEIRVHQPETQWFACSLCVRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLGVRPNVEPNELAELFYPDSKDMDEDQLIGLIRKDLASGIYQRFYSITNQSGYEMDLDSSETDSDMDGEPEDPQNRRRRKNRKCSYTCELCQEKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGTKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQSSGGSRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSKEKMYTCSKCSYKFMWPENLDLHVRLQHSESSSHSSPTGVSGGGRPRTGPGELDKDAGEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHTRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00531787;
80% Identity: -