Basic Information

Insect: Drosophila burlai
Gene Symbol: -
Assembly: GCA_008042655.1
Location: VNJT01009789.1:5783-8865[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.6e-07 7.3e-05 23.1 3.0 1 23 201 224 201 224 0.95

2 17 4.3e-05 0.0033 17.9 0.1 1 23 231 253 231 253 0.97

3 17 0.21 16 6.3 0.1 2 23 285 306 284 306 0.94

4 17 5.2e-05 0.004 17.6 2.3 1 23 398 421 398 421 0.97

5 17 0.25 19 6.0 0.6 1 19 428 446 428 449 0.93

6 17 0.068 5.2 7.8 6.3 1 23 458 480 458 480 0.95

7 17 6.9e-06 0.00053 20.4 0.4 1 23 487 510 487 510 0.97

8 17 0.00039 0.03 14.9 2.4 2 23 518 539 517 539 0.96

9 17 0.018 1.4 9.6 0.1 2 21 566 585 565 586 0.94

10 17 0.008 0.62 10.7 2.6 1 23 636 659 636 659 0.98

11 17 0.014 1.1 10.0 0.3 1 23 696 719 696 719 0.96

12 17 0.00013 0.0097 16.4 1.6 2 23 760 782 759 782 0.95

13 17 0.0028 0.21 12.2 0.1 1 23 796 818 796 818 0.95

14 17 1.8e-05 0.0014 19.0 1.0 1 23 824 846 824 846 0.99

15 17 3.3e-07 2.5e-05 24.5 2.6 1 23 852 874 852 874 0.98

16 17 3.7e-05 0.0028 18.1 3.8 1 23 880 902 880 902 0.97

17 17 2.6e-05 0.002 18.6 0.5 1 22 908 929 908 932 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.6e-07	7.3e-05	23.1	3.0	1	23	201	224	201	224	0.95
2	17	4.3e-05	0.0033	17.9	0.1	1	23	231	253	231	253	0.97
3	17	0.21	16	6.3	0.1	2	23	285	306	284	306	0.94
4	17	5.2e-05	0.004	17.6	2.3	1	23	398	421	398	421	0.97
5	17	0.25	19	6.0	0.6	1	19	428	446	428	449	0.93
6	17	0.068	5.2	7.8	6.3	1	23	458	480	458	480	0.95
7	17	6.9e-06	0.00053	20.4	0.4	1	23	487	510	487	510	0.97
8	17	0.00039	0.03	14.9	2.4	2	23	518	539	517	539	0.96
9	17	0.018	1.4	9.6	0.1	2	21	566	585	565	586	0.94
10	17	0.008	0.62	10.7	2.6	1	23	636	659	636	659	0.98
11	17	0.014	1.1	10.0	0.3	1	23	696	719	696	719	0.96
12	17	0.00013	0.0097	16.4	1.6	2	23	760	782	759	782	0.95
13	17	0.0028	0.21	12.2	0.1	1	23	796	818	796	818	0.95
14	17	1.8e-05	0.0014	19.0	1.0	1	23	824	846	824	846	0.99
15	17	3.3e-07	2.5e-05	24.5	2.6	1	23	852	874	852	874	0.98
16	17	3.7e-05	0.0028	18.1	3.8	1	23	880	902	880	902	0.97
17	17	2.6e-05	0.002	18.6	0.5	1	22	908	929	908	932	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTATTGTGTCGCACCTGCGACTCCACGGACACCGACAATCTTCTGAAGCTGACCACGCCCTCGAAAAAGTATCCGGACAAGCTGCTCTCGGAGATTTTGACGGAGCTAACCGATATCCATGTGGACGCGAGTGGCAATCAGAAGCTGCCGCAGTGCTTGTGTAGCAGCTGCGCGAAGAAACTAATGGGTGCATATTGCTTCGTGAAGCAGGCACTAGCCGCCAACGAACTGTTGATGAAGCACTTAAAGAACGGCTCTGCACCGACCGCCACCGACTGCCTACAGGAGGCGCCCATGGAGCTGTGCGCCGAACAGCATGTGGAGGTCAAAATGGAAACGGAGGACGAGGAGTGTGGCGACAACGATGTTAGTATCACCTGCTGCGACCTGCCAGAACCGGGCGAACGGGATATGGAGAGCAAGAAGTCCGTGGATCCACTGACCATGATTGAGACGGTGAAGCTGGAGGGGGAACCACCCAGCCTGGAGAGGCCGGTGGCCACCTCGGACTTTGATGATGAAGACTCCCTGGATAACTTGCCCCTAAATAAGCGCATCCAAAAGTGGAAGGCTAGAAGATTGCCCGTTTTCAAGTGCCACGATTGCCCAAGGAGTTTCAAGAGAAACGAGTACCTAAAGCGCCACGAAATCCGTGCCCATCAGCCGGAGACCCACTGGTTCGCCTGCTCCCTCTGCGCTCGCAAGTTCAGCCGCAACGAAGCCCTCGAGGCTCACCTGAAGGTGCACAGGAACTCGAAGCGATCGGCCAACATCAGCGAGCACAAGAAGGCCAAGGCGGTGGATGTGAATCTCTGCAAGCCGCACGGCTACAAGCTCATCGAGTGCATGATCTGTCAGAGCCAGTACAACAAGATTGCGGATCTGCGAAGGCACTTGGAAGAGCATCCGGATATTGTCAGCCTGGCCGTTCGTCCAAATGTGGAGCCCAATGAGCTGGCGGAACTATTTTATCCCGACTCCAAGGACATGGATGAAGAGCAGTTGATCGGTGTAATCCGCAAGGACCTGGCTTCGGGCATCTATCAACGTTTTTACTCGATTACCAACCAGAGTGGTTACGAAATGGATCTAGACAGCTCGGAGACTGACAGCGACGGTGTGGACTGTGACCCAGAGGATCAGCAGAACAAGAGGCGACGCAAGAACCGCAGGGGTTGCTACACCTGCGAACTGTGTCAGCAGAAGTTTCCGCGGAAATATCAGCTTTATGATCATCAACGGCAGAGCCACAGCTGGTCCGAGGCTCCGCATGTCTGCGGACGGTGCGATGGACGCTTTGTAAGCCTGCAACTGCTGCGGCATCACAACGAGTCGCAGTGCCGGAATGCACAGAAGCGCTTCCTCTGCCACAAATGCCCGCTGCGCTTCCGGTGGAAACACAATCTGAGGACCCATTTCCGCGAGCATAGGATTACAAACCAAACCTTCGAGTGCCCCGAGTGCAAGCGGGTCTTTGACAAAAAGAAGTCCCTCACCGTTCACCTGCTCAGCGTCCATGCCGAGGAATCAAAGCTCATTCCCTGCCAATGGTGTAGTCGCAAGTTCTATCGGCATGACTACCTGGTGAAGCATCTGAAGCGCCATGGCCTCAAGGAGCAGGACATTCCACTGGCCGAGACCCTGATAGCGGCCACTTCGCGGCCAAATGGAACGAAGCGAATCACCTGCCGGATGTGCAATCTACACTTTGAGCGGATTGTGGATCTGCGGGCTCACAtccagctggagctgaagctgtcATTGTCGCTCCACCAGAGCTACGACTCGCCGCATAATTATTCGATCACCAACGAGTCCGGTTtcgagctgcagctggaggatTCGGAGACGGAGGACGAGATGCAGTcaagcagcggcggcggtcgTCACGTTTACATCTGCGAGCTGTGCAGTGTGCAGTGCAAGCGGAAATTCGAAATGATCCAGCATCAGAGGACAATGCATCGATTCGACAAAATGCCGCATGAATGCGACGACTGCATCTTCAAGTGTGTGTCCAAGAGCATCATGGATCACCATCGGCTGGGGCAGTGCAGCAGCAAGGAGAAGATGTACGCCTGCAGCAAGTGTTCCTACAAGTTCATGTGGCCCGAGAATCTGGAGCAGCACGTGCGCTTGCAGCACAGCAAATCCTCACCCATCAGCAATCCCACAGGCGACGCCAGCAGTGGGGGGCCCCGGACTGGACCCGGTGACCAGGATAAGGATAAGGACGCCGGCGGCGAAGATGGGGTACCATTGTTGCAGTGTCCGCATTGCGATCGCACCTACCAGATGAAGTCCCGCCTGAATAACCACATCCGGGATGTTCACGTAAACGGCGATCGCAAGCGCAAGGAGGCAATCAAGCGTTTCCTGTGCTCGCTGTGCGGCATGGAGACCCGATCGGCGGCCGCCCTTGTAACGCACACGCGTCGCCACACCGGCGAGAAGCCCTTCAAGTGCGATCTGTGCGAGATGGCCTTTCCCAGGCACTCGGAGTTGGCCTCCCATCGCCGAATGCACACCGGTGAGAAGCCATTCCACTGCACAGTCTGCGGCAAGGATTTCGCCCGCTCCGACAAGCTCAAGCGCCACATGCTCACCCACAGCGGCCTGAAGCCGCACAAGTGTACGTACTGCGAGAAGAGCTATCGCCAGGCGAAGGATCTGAAGCTCCATCTGCAGCAGCATACCGGCGAGTGTCCGTTCGTTTGCGGCACCTGCGGCGAACGATTTATACAGAGCAGCACGCTGGAGAAGCACCGCCTGATGCGGCGTCACTTTGACGAAGTAGAAGCTTGGCTAAGGcgtcaaaaataa
Protein Sequence: MKLPVLCRTCDSTDTDNLLKLTTPSKKYPDKLLSEILTELTDIHVDASGNQKLPQCLCSSCAKKLMGAYCFVKQALAANELLMKHLKNGSAPTATDCLQEAPMELCAEQHVEVKMETEDEECGDNDVSITCCDLPEPGERDMESKKSVDPLTMIETVKLEGEPPSLERPVATSDFDDEDSLDNLPLNKRIQKWKARRLPVFKCHDCPRSFKRNEYLKRHEIRAHQPETHWFACSLCARKFSRNEALEAHLKVHRNSKRSANISEHKKAKAVDVNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLAVRPNVEPNELAELFYPDSKDMDEEQLIGVIRKDLASGIYQRFYSITNQSGYEMDLDSSETDSDGVDCDPEDQQNKRRRKNRRGCYTCELCQQKFPRKYQLYDHQRQSHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLRTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGTKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQSSSGGGRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSKEKMYACSKCSYKFMWPENLEQHVRLQHSKSSPISNPTGDASSGGPRTGPGDQDKDKDAGGEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHTRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00531787;
80% Identity: -