Basic Information

Insect: Drosophila mimetica
Gene Symbol: -
Assembly: GCA_037075245.1
Location: JBAMCH010000023.1:2212213-2215239[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.5e-05 0.0011 19.4 1.4 1 23 204 227 204 227 0.97

2 17 0.00054 0.041 14.5 0.2 1 23 234 256 234 256 0.97

3 17 0.22 17 6.3 0.1 2 23 288 309 287 309 0.94

4 17 0.00038 0.029 15.0 1.0 3 23 401 422 399 422 0.96

5 17 0.26 20 6.1 0.6 1 19 429 447 429 450 0.93

6 17 0.07 5.4 7.8 6.4 1 23 459 481 459 481 0.95

7 17 7.2e-06 0.00055 20.4 0.4 1 23 488 511 488 511 0.97

8 17 0.0004 0.031 14.9 2.4 2 23 519 540 518 540 0.96

9 17 0.019 1.4 9.6 0.1 2 21 567 586 566 587 0.94

10 17 0.0083 0.64 10.7 2.6 1 23 636 659 636 659 0.98

11 17 0.088 6.7 7.5 0.5 1 23 696 719 696 719 0.93

12 17 0.00013 0.01 16.4 1.6 2 23 747 769 746 769 0.95

13 17 0.00039 0.03 14.9 0.1 1 23 783 805 783 805 0.95

14 17 1.9e-05 0.0015 19.1 1.0 1 23 811 833 811 833 0.99

15 17 3.4e-07 2.6e-05 24.6 2.6 1 23 839 861 839 861 0.98

16 17 3.8e-05 0.0029 18.1 3.8 1 23 867 889 867 889 0.97

17 17 2.6e-05 0.002 18.6 0.5 1 22 895 916 895 919 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.5e-05	0.0011	19.4	1.4	1	23	204	227	204	227	0.97
2	17	0.00054	0.041	14.5	0.2	1	23	234	256	234	256	0.97
3	17	0.22	17	6.3	0.1	2	23	288	309	287	309	0.94
4	17	0.00038	0.029	15.0	1.0	3	23	401	422	399	422	0.96
5	17	0.26	20	6.1	0.6	1	19	429	447	429	450	0.93
6	17	0.07	5.4	7.8	6.4	1	23	459	481	459	481	0.95
7	17	7.2e-06	0.00055	20.4	0.4	1	23	488	511	488	511	0.97
8	17	0.0004	0.031	14.9	2.4	2	23	519	540	518	540	0.96
9	17	0.019	1.4	9.6	0.1	2	21	567	586	566	587	0.94
10	17	0.0083	0.64	10.7	2.6	1	23	636	659	636	659	0.98
11	17	0.088	6.7	7.5	0.5	1	23	696	719	696	719	0.93
12	17	0.00013	0.01	16.4	1.6	2	23	747	769	746	769	0.95
13	17	0.00039	0.03	14.9	0.1	1	23	783	805	783	805	0.95
14	17	1.9e-05	0.0015	19.1	1.0	1	23	811	833	811	833	0.99
15	17	3.4e-07	2.6e-05	24.6	2.6	1	23	839	861	839	861	0.98
16	17	3.8e-05	0.0029	18.1	3.8	1	23	867	889	867	889	0.97
17	17	2.6e-05	0.002	18.6	0.5	1	22	895	916	895	919	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTGATTTGTCGCACCTGCGACTCCACGGACACCGACAACCTGCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGCTGCTTTCGGAGATTCTGTGCGAGCTAACCGAAATCAATTTGGATGCCAGTGGAAGCCAGAAGCTGCCGCAGTGCCTGTGCAGCGGATGCACCAAGAAGTTAATGGGTGCCTACTGCTATGTGAAGCAGGCGCTGGCCGCCAACGAGATGTTGATGAAGCACCTGCGAAACGGAGCTGCTCCCACAACCACCGATTGCCTGCAGGAGGCGCCCATGGAACTGTGTGCCGAGCAGCATGTAGAGGTCAAGCTGGAgacggaggacgaggacggcGACAACGATGTTAGCATCACCTGCTCCGAACTCCCGGAACCGGATGAAATGGACGTGGAGAGCAAGAAGTCCGTGGATCCGCTGACCATGATTGAGACGGTGAAGCTGGAAACCGAACCGAGAAGTGTGCAGAAGCCGTCGGAAGACGATCTCGCGTCGGACTTTGAGGACGAGGACTCCCTGGATGACCTGCCTTTGGATAGGCGCATTCAACAGTGGAAGACGGGAAGGAAGGCGTCTGCATTCAAGTGCCAGGACTGCCCGAGGAGCTTCAAACGAGTCGAGTTCTTGAAACGCCATGAAATGCGCGTGCACAAGCAGGATACCCGCTCATTCGCCTGCTCTCTGTGCATTCGGAAATTTAGCCGCAGCGAAGCTTTAGAAGCGCACTTGAAGGTCCATCGGAACTCCAAGCGATCGGCCAACATAAGCGAGCACAAGAAGGCCAAGGCGGTGGATCTCAATCTCTGCAAGCCGCACGGCTACAAGCTAATCGAGTGCATGATCTGCCAGAGTCAGTACAACAAGATAGCCGATCTGCGGCGGCACTTGGAGGAGCATCCCGAGATAGTCAGCGTGTGCGGGCGGCCAAATGTGGAGCCGCACGAGATGGCTGAGCTGTTTTATCCCGACTCCAAAGACCTGGGTGAGGAGCAGTTGATTAGCCTGATTCGCAAGGATCTGGCGGCGGGAATCTATCAACGTTTCTATTCGATAACCAACCAAAGTGGATACGAAATGGACCTGGACAGCTCGGAGACGGACAGCGATCTGGACGGAGACCCCGAGGATCAGCAGAAGAGGCGAAAGAAGTCGCGCAAGGCTACCTACGGCTGCGAACTGTGCCAGCAGAAGTTCCCGCGGAAATATCAGCTCTATGACCACCAGCGCCAGACGCACAGTTGGTCAGAGGCTCCCCACGTCTGCGGGCGCTGCGATGGACGCTTTGTGAgcctgcagctgctgcggcACCACAACGAGTCGCAGTGCAGGAATGCGCAGAAACGATTCCTCTGTCACAAATGCCCGCTTCGTTTCCGCTGGAAGCACAACCTGAAAACACACTTCCGCGAGCACAGGATTACAAACCAGACCTTTGAGTGTCCCGAGTGCAAAAGGGTTTTCGACAAAAAGAAATCGCTTACCGTTCACCTGCTCAGCGTGCATGCCGAGGAATCGAAGCTGATACCCTGCCAGTGGTGCAGTCGCAAGTTCTACCGCCACGACTACCTGGTGAAGCACCTGAAGCGGCACGGACTCAAGGAGCAGGACATTCCACTGGCCGAGACCCTGATTGCGGCCACATCGCGGCCAAACGGGACGAAGCGTATTACCTGTCGCATGTGCAACCTGCACTTTGAACGCATCGTCGATCTGAGAGCCCACATTCAGCTGGAGCTGAAGCTGTCTCTGTCGCTGCACCAGAGCTACGACTCCCTGCACAATTACTCGATAACCAACGAGTCCGGCTTCGAGTTGCAGCTGGAGGATTCGGAGACCGAGGACGAAATGCAACCAGCTGGTGGCAGTCGTCCTGTTTACATCTGCGAGCTGTGCAGCGTGCAATGCAAACGGAAATTCGAAATGATCCAGCATCAGCGGACGATGCATCGTTTCGACAAGATGCCTCACGAGTGCGATGACTGCATTTTCAAATGTGTGTCTAAGAGCATCATGGATCACCATCGGCTGGGTCAGTGCAGCAGTACAGAAAAGAAGCATCCCTGCGAGAAGTGCTCCTACAAGTTCATGTGGCCCGAGAATCTGGAACAACACGTTCTTCTGCAGCACAGCAAATCCTCCGGCGTCAAGCGAACGTCTGATGGTGGTGACCTGGACAAGGATGCCGCCGAGGACGGGGTGCCGCTGCTGCAGTGTCCGCACTGCGATCGCACCTACCAGATGAAGTCGCGCCTCAACAACCACATCCGCGACGTGCACGTTAACGGCGACCGCAAGCGCAAGGAGGCGATCAAGCGCTTCCTCTGCTCCCTGTGCGGCATGGAGACGAGATCCGCAGCGGCCCTGGTGACCCACATGCGTCGGCACACGGGCGAAAAGCCCTTCAAGTGCGATCTGTGCGAGATGGCCTTTCCGCGGCACTCGGAGCTGGCCTCCCATCGCCGCATGCACACCGGCGAGAAGCCATTCCACTGCACCGTTTGCGGCAAGGACTTCGCCCGCTCCGACAAGCTCAAGCGACACATGCTCACCCACAGCGGCTTGAAGCCGCACAAGTGCACCTACTGCGAGAAGAGCTACCGCCAGGCGAAGGATCTGAAGCTCCACCTGCAGCAGCACACCGGCGAGTGTCCCTTCGTGTGCGGCACCTGCGGCGAGCGCTTCATACAGAGCAGCACGCTGGAAAAGCACAGGCTGATGCGACGACACTTTGACGAGGTGGAGGCGTGGCTAAGGCGCCAGAAGTAG
Protein Sequence: MKLPVICRTCDSTDTDNLLKLATPSKKYPDKLLSEILCELTEINLDASGSQKLPQCLCSGCTKKLMGAYCYVKQALAANEMLMKHLRNGAAPTTTDCLQEAPMELCAEQHVEVKLETEDEDGDNDVSITCSELPEPDEMDVESKKSVDPLTMIETVKLETEPRSVQKPSEDDLASDFEDEDSLDDLPLDRRIQQWKTGRKASAFKCQDCPRSFKRVEFLKRHEMRVHKQDTRSFACSLCIRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPEIVSVCGRPNVEPHEMAELFYPDSKDLGEEQLISLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDPEDQQKRRKKSRKATYGCELCQQKFPRKYQLYDHQRQTHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGTKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSLHNYSITNESGFELQLEDSETEDEMQPAGGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSTEKKHPCEKCSYKFMWPENLEQHVLLQHSKSSGVKRTSDGGDLDKDAAEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00604984;
80% Identity: -