Basic Information

Insect: Drosophila auraria
Gene Symbol: -
Assembly: GCA_008042615.1
Location: VNJW01011138.1:1783-4852[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.3e-07 9.3e-05 22.9 3.1 1 23 205 228 205 228 0.95

2 17 0.00044 0.044 14.5 0.2 1 23 235 257 235 257 0.97

3 17 0.18 18 6.3 0.1 2 23 289 310 288 310 0.94

4 17 4.4e-05 0.0044 17.6 2.3 1 23 401 424 401 424 0.97

5 17 0.21 21 6.1 0.6 1 19 431 449 431 452 0.93

6 17 0.058 5.8 7.8 6.4 1 23 461 483 461 483 0.95

7 17 5.9e-06 0.00059 20.4 0.4 1 23 490 513 490 513 0.97

8 17 0.00033 0.033 14.9 2.4 2 23 521 542 520 542 0.96

9 17 0.015 1.5 9.6 0.1 2 21 569 588 568 589 0.94

10 17 0.0069 0.69 10.7 2.6 1 23 638 661 638 661 0.98

11 17 0.012 1.2 10.0 0.4 1 23 698 721 698 721 0.96

12 17 0.00011 0.011 16.4 1.6 2 23 754 776 753 776 0.95

13 17 0.0024 0.24 12.2 0.1 1 23 790 812 790 812 0.95

14 17 1.6e-05 0.0016 19.1 1.0 1 23 818 840 818 840 0.99

15 17 2.8e-07 2.8e-05 24.5 2.6 1 23 846 868 846 868 0.98

16 17 3.1e-05 0.0031 18.1 3.8 1 23 874 896 874 896 0.97

17 17 2.2e-05 0.0022 18.6 0.5 1 22 902 923 902 926 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.3e-07	9.3e-05	22.9	3.1	1	23	205	228	205	228	0.95
2	17	0.00044	0.044	14.5	0.2	1	23	235	257	235	257	0.97
3	17	0.18	18	6.3	0.1	2	23	289	310	288	310	0.94
4	17	4.4e-05	0.0044	17.6	2.3	1	23	401	424	401	424	0.97
5	17	0.21	21	6.1	0.6	1	19	431	449	431	452	0.93
6	17	0.058	5.8	7.8	6.4	1	23	461	483	461	483	0.95
7	17	5.9e-06	0.00059	20.4	0.4	1	23	490	513	490	513	0.97
8	17	0.00033	0.033	14.9	2.4	2	23	521	542	520	542	0.96
9	17	0.015	1.5	9.6	0.1	2	21	569	588	568	589	0.94
10	17	0.0069	0.69	10.7	2.6	1	23	638	661	638	661	0.98
11	17	0.012	1.2	10.0	0.4	1	23	698	721	698	721	0.96
12	17	0.00011	0.011	16.4	1.6	2	23	754	776	753	776	0.95
13	17	0.0024	0.24	12.2	0.1	1	23	790	812	790	812	0.95
14	17	1.6e-05	0.0016	19.1	1.0	1	23	818	840	818	840	0.99
15	17	2.8e-07	2.8e-05	24.5	2.6	1	23	846	868	846	868	0.98
16	17	3.1e-05	0.0031	18.1	3.8	1	23	874	896	874	896	0.97
17	17	2.2e-05	0.0022	18.6	0.5	1	22	902	923	902	926	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTAATTTGTCGCACCTGCGACTCCACGGATACCGACAGCCTCCTTAAGCTGGCCACGCCCTCGAAGAAGTACCCGGACAAGCTGCTCTCGGATATTTTGGCGGAGCTAACTGATATCGATGTGGATGCGAGTGCCAGTCAAAAGCTGCCGCAGTGCTTGTGCAGCAGCTGCATCAAAAAACTAATGGGTGCCTATTGCTTCGTTAAGCAGGCGCTGGCCGCCAACGAACTGCTGATGAGGCACTTGAAGAACGGTGCTGCACCGACCGCCACCGACTGTCTGCAGGAGGCGCCCATGGAGCTGTGCGCGGAGCAGCATGTGGAGGTCAAGATGGAGACGGAGGACGAAGAATGTGGCGACAACGATGTTAACATAACATGCTCCGAGCTGCCAGAACCGGGCGAACGGGATGTGGAGAGCAAGAAGTCTGTGGATCCACTGACCATGATTGAGATGGTGAAGCTGGAGGGCGAACCGCCAAGCGTGGAGAGGCCGGCGGAAGAAGAAGAACCTGCCTCGGAGTTCGACGATGATGACTCCCTGGATAACCTGCCTCTAACCAAACGCATCCAGAAGTGGAAGGCTAGAAGGATGTCCGTTTTCAAATGCCACGATTGCCCGAGGAGTTTCAAGAGAAACGAGTACCTAAAACGCCACGAAATCCGAGTCCACAAGCCGGAGACCCAATGGTTCGCCTGCTCCCTTTGCATTCGCAAGTTTAGTCGCAGCGAAGCCCTCGAGGCTCACCTCAAAGTCCACAGGAACTCCAAGCGATCGGGCAACATCAGCGAGCACAAGAAGGCAAAGGCGGTAGATCTGAATCTTTGCAAGCCGCACGGCTACAAGCTCATCGAGTGCATGATCTGCCAGAGCCAGTACAACAAGATTGCGGATCTGCGACGGCACTTGGAGGAGCATCCAGATATTGTAAACTTGGGCGCTCGTCCAAATCTGGAGCCAAGTGAGCTGGCAGAACTGTTTTATCCCGACTCCAAGGACCTGGGCGAAGAGCAGTTGATCGACCTAATTCGGAAGGATTTGGCGTCGGGCATTTATCAACGTTTCTACTCGATAACCAACCAGAGTGGCTACGAAATGGACCTGGACAGCTCCGAGACGGACAGCGATCTGGACGGTGAGCCCGAGGATCAGCAAAACAAGAGGCGGCGGAAGAACCGCAAGGGCAGCTACACCTGCGAACTCTGCCAGCAGAAGTTTCCGCGGAAATATCAGCTCTATGATCATCAGCGGCAGAGCCACAGCTGGTCAGAGGCGCCACATGTCTGCGGGCGGTGCGATGGACGGTTTGTcagcctgcagctgctgcgtcATCACAACGAGTCGCAGTGTCGGAATGCACAGAAGCGGTTTCTCTGTCACAAATGCCCGCTCCGCTTCCGATGGAAACATAATCTGAAAACCCATTTCCGAGAGCATAGAATCACAAATCAGACCTTCGAGTGTCCCGAGTGCAAGCGGGTGTTTGACAAAAAGAAATCCCTCACCGTTCACCTGCTTAGCGTCCATGCCGAGGAATCAAAGCTGATACCCTGCCAGTGGTGCAGCCGCAAGTTCTACCGACATGACTACCTGGTGAAGCATCTGAAGCGCCATGGCCTCAAGGAGCAGGACATTCCACTGGCCGAGACATTGATTGCGGCCACCTCGCGGCCAAATGGAACCAAGAGAATAACCTGCCGGATGTGTAATCTGCACTTTGAGCGTATTGTGGATTTGCGGGCCCACAtccagctggagctgaagctgtcCTTGTCGCTCCACCAGAGCTACGACTCGCCACACAATTACTCGATCACAAACGAGTCCGGCTTTGAGTTGCATCTAGAGGATTCGGAGACGGAGGATGAGCTGCAGTCGAGTGGCGGCAGTCGTCACGTTTACATCTGCGAACTGTGCAGCGTGCAGTGCAAGCGGAAATTCGAGATGATCCAGCATCAGCGGACAATGCACCGGTTCGACAAGATGCCGCACGAGTGCGATGACTGCATATTCAAGTGTGTGTCCAAGAGCATCATGGACCATCACCGCCAGGGTCAGTGCAGCAGCAAGGACAAGATGTACTCTTGCGGCAAGTGCTCCTACAAGTTCATGTGGCCCGAGAACCTGGAGCAGCACGTGCGACTCCAGCACAGCGAATCTTCTTCCAGCAATCCAACAGACGGCAGGCCAGCGACTGGACCCGGTGACCTGGATAAGGACGCCGGCGAGGATGGGGTGCCGTTGTTGCAGTGTCCCCATTGCGATCGCACCTACCAGATGAAGTCCCGCCTAAACAACCACATCCGCGATGTGCATGTAAACGGCGATCGCAAGCGCAAGGAGGCGATCAAGCGTTTCCTGTGCTCCCTGTGCGGCATGGAGACCCGATCTGCCGCCGCCCTCGTTACCCACACCCGACGTCACACCGGCGAGAAGCCCTTCAAGTGCGATCTGTGCGAGATGGCCTTTCCAAGGCATTCGGAGCTAGCCTCTCACCGCAGGATGCACACCGGGGAGAAGCCATTCCACTGCACAGTCTGCGGCAAGGACTTTGCTCGCTCCGACAAGCTCAAGCGCCACATGCTCACCCACAGCGGTCTGAAGCCGCACAAGTGTACGTACTGCGAGAAGAGCTATCGTCAGGCCAAGGATCTGAAGCTCCACCTGCAGCAGCACACCGGCGAGTGTCCGTTCGTGTGTGGCACCTGTGGCGAGCGATTTATACAGAGCAGCACGCTGGAGAAGCACCGCTTGATGCGACGCCACTTTGACGAGGTGGAAGCCTGGCTAAGGCGGCAAAAATAG
Protein Sequence: MKLPVICRTCDSTDTDSLLKLATPSKKYPDKLLSDILAELTDIDVDASASQKLPQCLCSSCIKKLMGAYCFVKQALAANELLMRHLKNGAAPTATDCLQEAPMELCAEQHVEVKMETEDEECGDNDVNITCSELPEPGERDVESKKSVDPLTMIEMVKLEGEPPSVERPAEEEEPASEFDDDDSLDNLPLTKRIQKWKARRMSVFKCHDCPRSFKRNEYLKRHEIRVHKPETQWFACSLCIRKFSRSEALEAHLKVHRNSKRSGNISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVNLGARPNLEPSELAELFYPDSKDLGEEQLIDLIRKDLASGIYQRFYSITNQSGYEMDLDSSETDSDLDGEPEDQQNKRRRKNRKGSYTCELCQQKFPRKYQLYDHQRQSHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGTKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELHLEDSETEDELQSSGGSRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQCSSKDKMYSCGKCSYKFMWPENLEQHVRLQHSESSSSNPTDGRPATGPGDLDKDAGEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHTRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00531787;
80% Identity: -