Dgun008121.1
Basic Information
- Insect
- Drosophila gunungcola
- Gene Symbol
- -
- Assembly
- GCA_011057485.1
- Location
- WTSR01005050.1:2185533-2188565[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 2.5e-05 0.0023 18.1 2.0 1 23 204 227 204 227 0.97 2 12 0.00031 0.028 14.7 0.2 1 23 234 256 234 256 0.97 3 12 0.12 12 6.5 0.1 2 23 288 309 287 309 0.94 4 12 2.7e-05 0.0025 18.1 1.5 1 23 396 419 396 419 0.97 5 12 0.15 14 6.3 0.6 1 19 426 444 426 447 0.93 6 12 0.04 3.7 8.1 6.4 1 23 456 478 456 478 0.95 7 12 4.1e-06 0.00038 20.6 0.4 1 23 485 508 485 508 0.97 8 12 4.9e-05 0.0046 17.2 1.1 2 23 516 537 515 537 0.96 9 12 0.011 0.99 9.9 0.1 2 21 564 583 563 584 0.94 10 12 0.0047 0.44 11.0 2.6 1 23 633 656 633 656 0.98 11 12 0.036 3.4 8.2 0.6 1 23 694 717 694 717 0.93 12 12 0.00025 0.023 15.0 1.1 2 21 750 769 749 770 0.95
Sequence Information
- Coding Sequence
- ATGAAGCTGCCGGTGATTTGTCGCACCTGCGACGCCACCGACACCGACAACCTCCTTAAGCTCGCCACGCCCTCAAAAAAGTATCCGGACAAGCTGCTATCGGAGATCCTGTGCGAGCTGACCGAAATCAATATGGATGCGACTGAAAGCCAGAAACTGCCGNAGTGTTTGTGTAGCGGCTGCACCAAGAAATTGATGGGTGCCTATTGCTATGTGAAGCAGGCGCTGGCCGCCCACGAATTGCTGATGAAGCACCTGAAGAACGGAGCTGCTGCATCGACCACCGACTGCTTGCAGGAGGCCCCCATGGAGCTGTGTGCCGAGCAGCACGTGGAGGTCAAGCTGGAGACCGAGGACGAGGACTGTGGCGACAACGATGTCAGCATCGCTTGCTCCGAACTGCCGGAACCGGACGAAATGGATGTGGAGAGCAAGAAGTCCGTGGATCCTCTGACCATGATTGAGACGGTGAAGCTGGAAACAGAACCGCAGAGCATAGGAAAACCAACGGATGAAGAACCTGCCTCGGACTTCGATGACGAGGACTCCCTGGATAACCTGCCCCTGTATAAGCGCATTCAAAAGTGGAAGATGGGCAGGAAGTCTGTATTCAAATGCCAGGACTGCCCGAGAAAATTCAAACGAGTCGAGTTTCTTAAACGCCATGAAAACCGCGTCCACAAGGCGGATACACGCTCGTTCGCATGCTCCCTCTGCATTCGTAAATTCAGCCGCAGCGAGGCTCTTGAGGCTCACCTGAAAGTCCATCGAAACTCGAAGCGATCGGCAAACATAAGCGAGCACAAGAAGGCCAAGGCGGTGGATCTGAATCTGTGTAAACCGCATGGCTACAAACTAATCGAGTGCATGATCTGCCAGAGCCAGTACAACAAGATTGCCGATCTGCGGCGGCATTTGGAGGAGCATCCCGAGATAGTCAGCCTTTGCGGTCGACCAAATGCGGAGCCTCACGAGCTGTTTTATCCCGACTGCAAGGACCTGGACGAGGAGCAGTTGATCAGCTTGATTCGAAAGGATCTGGCGGCGGGCATTTACCAGCGTTTCTATTCGATAACCAACCAGAGTGGCTACGAAATGGACCTGGACAGTTCGGAGACGGATAGCGATTTGGACGGAGATCCCGAGGATCAGCAAAAGAGGCGAAAGAAGAGCCACAAGAGCAGCTACAGCTGCGAGCTATGCCAGCAAAAATTCCCGCGGAAATATCAGTTATACGACCACCAGCGACAGGCCCACAGTTGGTCAGAGGCTCCTCATGTCTGCGGGCGGTGTGATGGACGCTTCGTGAGTCTGCAGCTGTTGCGGCACCACAACGAGTCCCAGTGCCGAAATGCGCAGAAGCGTTTCCTTTGCCACAAATGCCCGCTTCGCTTTCGCTGGAAACACAACCTGAAAACACATTTCCGCGAGCACAGGATTACAAATCAAACCTTTGAGTGTCCAGAGTGCAAGCGGGTCTTTGACAAAAAGAAATCGCTTACCGTTCACCTGCTCAGCGTACATGCCGAGGAATCTAAACTGATCCCTTGCCAGTGGTGCAGTCGCAAGTTCTACCGCCGCGACTACTTGGTTAAACACCTGAAGCGGCACGGCCTTAGGGAGCAAGACATTCCGCTGGCCGAGACTTTGATAGCGGCCACCTCGCGGCCAAACGGAGCGAAGCGCATTACCTGCCGGATGTGCAATCTGCACTTTGAGCGTATCGTTGATCTGCGAGCCCACATCCAGCTGGAGCTAAAGCTGTCCCTGTCGCTGCACCAGAGCTACGACTCACTGCACAATTACTCGATTACAAACGAGTCCGGGTTCGAGCTGCAGCTGGACGACTCAGAGACGGAGGACGAGATGCAGCCGGGCGGTGGAAGTCGGCCCGTTTATATCTGCGAGCTGTGCAGCGTGCAGTGCAAACGGAAATTCGAAATGATCCAGCATCAGCGGACGATGCACCGCTTCGACAAAATGCCACACGAATGCGAGGACTGCATCTTCAAttcTTTATGTTTTCAGAGCATCATGGATCACCATCGGCAGGGCCAGTGTAGCAGTTCAGAAAAGAAGCATCCGTGCAGCAAGTGCTCCTACAAATTCATGTGGCCCGATAATCTGGAACAGCACGTCTTACTGCAGCACAGCGAATCCTCGGCCAGCAATCTGACGGGCGCCAGGTGCTCGACTGGCACGGGTGACCTGGACAAGGATGCCGCCGAGGATGGCGTGCCGCTGCTGCAGTGCCCACATTGTGATCGCACCTATCAGATGAAGTCACGTCTGAACAATCACATACGCGATAGCAGCACGCTGGAGAAGCACCGGCTGATGCGACGCCACTTCGATGAGGTGGAGGCGTGGTTGAGGCGCCAAAAATAG
- Protein Sequence
- MKLPVICRTCDATDTDNLLKLATPSKKYPDKLLSEILCELTEINMDATESQKLPXCLCSGCTKKLMGAYCYVKQALAAHELLMKHLKNGAAASTTDCLQEAPMELCAEQHVEVKLETEDEDCGDNDVSIACSELPEPDEMDVESKKSVDPLTMIETVKLETEPQSIGKPTDEEPASDFDDEDSLDNLPLYKRIQKWKMGRKSVFKCQDCPRKFKRVEFLKRHENRVHKADTRSFACSLCIRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPEIVSLCGRPNAEPHELFYPDCKDLDEEQLISLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDPEDQQKRRKKSHKSSYSCELCQQKFPRKYQLYDHQRQAHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRRDYLVKHLKRHGLREQDIPLAETLIAATSRPNGAKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSLHNYSITNESGFELQLDDSETEDEMQPGGGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECEDCIFNSLCFQSIMDHHRQGQCSSSEKKHPCSKCSYKFMWPDNLEQHVLLQHSESSASNLTGARCSTGTGDLDKDAAEDGVPLLQCPHCDRTYQMKSRLNNHIRDSSTLEKHRLMRRHFDEVEAWLRRQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00581676;
- 90% Identity
- iTF_00604984;
- 80% Identity
- -