Dlat011928.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lacteicornis
Gene Symbol
-
Assembly
GCA_008044355.1
Location
VNKF01011871.1:276469-279519[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1e-06 8.2e-05 22.9 3.1 1 23 199 222 199 222 0.95
2 17 0.00047 0.039 14.5 0.2 1 23 229 251 229 251 0.97
3 17 0.19 16 6.3 0.1 2 23 283 304 282 304 0.94
4 17 4.7e-05 0.0039 17.6 2.3 1 23 395 418 395 418 0.97
5 17 0.23 18 6.1 0.6 1 19 425 443 425 446 0.93
6 17 0.062 5.1 7.8 6.4 1 23 455 477 455 477 0.95
7 17 6.3e-06 0.00052 20.4 0.4 1 23 484 507 484 507 0.97
8 17 0.00036 0.029 14.9 2.4 2 23 515 536 514 536 0.96
9 17 0.017 1.4 9.6 0.1 2 21 563 582 562 583 0.94
10 17 0.0074 0.6 10.7 2.6 1 23 632 655 632 655 0.98
11 17 0.013 1 10.0 0.4 1 23 692 715 692 715 0.96
12 17 0.00012 0.0095 16.4 1.6 2 23 748 770 747 770 0.95
13 17 0.0025 0.21 12.2 0.1 1 23 784 806 784 806 0.95
14 17 1.7e-05 0.0014 19.1 1.0 1 23 812 834 812 834 0.99
15 17 3e-07 2.5e-05 24.6 2.6 1 23 840 862 840 862 0.98
16 17 3.4e-05 0.0028 18.1 3.8 1 23 868 890 868 890 0.97
17 17 2.3e-05 0.0019 18.6 0.5 1 22 896 917 896 920 0.90

Sequence Information

Coding Sequence
ATGAAGCTGCCGGTAATTTGTCGCACCTGCGACTCCACGGACACCGACAACCTTCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGCTGTTCTCGGATATTTTGGCGGAGCTAACGGATATCAATGTGGATGCGAGTGCCAGTCAAAAGCTGCCGCAGTGCTtgtgcagcagctgcaccaAGAAACTAATGGCTGCCTATTGCTTCGTTAAGCAGGCGCTGGCCGCCAATGAACTGCTGATGAGGCACTTGAAGAACGCCACCGACTGTCTGCAGGAGGCGCCCATGGAGCTGTGCGCGGAGCAGCATGTGGAGGTCAAGCTGGAGacggaggacgaggagggTGGCGACAACGATGTCAGCATAACCTGCTCCGAGCTGCCAGAACCGGGCGAACGGGATGTGGAGAGCAAGAAGTCCGTGGATCCACTGACCATGATTGAGACGGTGAAGCTGGAGGGCGAACCGCCAAGCGTGGAGAGGCCGGCGGAAGAGGAGCCCGCTTCGGATTTCGAGGATGAAGACTCCCTGGATAACCTGCCCCTGAATAAGCGCATCCAGAAGTGGAAGGCCAGAGGGATGTCCGTTTTCAAGTGCCACGACTGCCCGAGGAGTTTCAAGAGAAACGAGTACCTTAAACGCCACGAAATCCGCGTCCACAAGCCGGAGACCCACTGGTTCGCCTGCTCCCTCTGCATTCGCAAGTTCAGCCGCAGCGAGGCCCTCGAGGCTCACCTGAAGGTCCACAGGAACTCGAAAAGATCGGCCAACATCAGCGAGCACAAAAAGGCCAAGGCGGTGGATCTGAATCTCTGCAAGCCGCACGGCTACAAGCTAATCGAGTGCATGATCTGCCAGAGTCAGTACAACAAGATTGCGGATCTGCGGCGGCACTTGGAGGAGCATCCAGATATTGTCAACTTGGGCACTCGTCCAAATCTGGAGCCAAGTGAGCTCGCTGAACTCTTTTATCCCGACTCCAAGGACCTGGGCGAAGAGCAGTTGATTGGCTTAATCCGCAAGGACTTGGCATCGGGCATTTATCAACGCTTCTACTCGATAACCAACCAGAGTGGCTACGAAATGGACCTGGACAGCTCGGAGACGGACAGCGATATGGACGTTGAGCACGAGGATCAGCAGAACACGAGGCGGCGTAAGAACCGCAAGGGCAGCTACACCTGCGAGCTCTGCCAGCAGAAGTTTCCGCGGAAATATCAGCTCTACGATCATCAGCGGCAGAGCCACAGCTGGTCAGAGGCGCCGCATGTCTGCGGACGCTGCGACGGACGCTTTGTcagcctgcagctgctgcggcatCACAACGAGTCGCAGTGCCGGAATGCGCAGAAGCGCTTCCTTTGCCACAAATGCCCGCTGCGATTCCGTTGGAAACACAATCTGAAAACCCATTTCCGAGAGCACAGGATCACAAACCAGACCTTCGAGTGTCCCGAGTGCAAGCGGGTGTTTGACAAAAAGAAATCCCTCACCGTTCACCTGCTCAGCGTCCATGCCGAGGAATCAAAGCTGATACCCTGCCAGTGGTGCAGCCGCAAGTTCTACCGGCATGACTACCTGGTGAAGCATCTGAAGCGCCACGGGCTCAAGGAGCAGGACATTCCACTGGCCGAGACACTGATTGCGGCCACCTCGCGGCCAAATGGAACGAAGCGAATCACCTGCCGGATGTGTAACCTGCACTTCGAGCGCATCGTAGATCTGCGAGCCCACAtccagctggagctgaagctctCCTTGTCGCTGCACCAGAGCTACGACTCGCCACACAATTATTCAATAACCAACGAGTCCGGCTTCGAGTTGCAGCTGGAGGATTCGGAGACGGAGGATGAGATGCAGTCGGGTGGCGGCAGTCGGCACGTTTACATCTGCGAGCTGTGCAGCGTGCAGTGCAAGCGGAAATTCGAGATGATCCAGCACCAGCGGACGATGCACCGGTTCGACAAGATGCCGCACGAGTGCGATGACTGCATCTTCAAGTGTGTGTCCAAGAGCATCATGGACCACCACCGGCTGGGGCAGTGCAGCAGCAAGGAGAAGCTGTACTCTTGCGGCAAGTGCTCCTACAAGTTCATGTGGCCCGAGAACCTGGAGCAGCATGTGCGACTCCAACACAGCGAATCTGCTTCCAGCCATCGCACAGACGGCAGGCGAGCGACTGCAACCGGTGACCTGGATAAGGACGCTGGGGAGGATGGGGTGCCATTGCTGCAGTGTCCCCATTGCGATCGCACCTACCAGATGAAGTCCCGCCTGAATAACCACATCCGGGATGTGCATGTGAACGGGGATCGTAAGCGCAAAGAGGCCATCAAGCGTTTCCTGTGCTCCCTGTGCGGCATGGAGACACGATCTGCCGCCGCCCTCGTTACCCACACCCGACGTCACACTGGGGAGAAGCCCTTCAAGTGCGATCTGTGCGAGATGGCCTTCCCGAGGCACTCGGAGCTGGCCTCACACCGCAGGATGCACACCGGTGAGAAGCCATTCCACTGCACAGTCTGCGGCAAGGACTTTGCTCGCTCCGACAAGCTCAAGCGCCACATGCTTACCCACAGCGGCCTGAAGCCGCACAAGTGCACGTACTGCGAGAAGAGCTACCGCCAGGCCAAGGATCTGAAGCTccacctgcagcagcacaCCGGCGAGTGTCCCTTCGTGTGCGGGACCTGCGGCGAGCGATTCATACAGAGCAGCACGCTGGAGAAGCACCGCTTGATGCGACGCCATTTTGACGAGGTGGAAGCCTGGCTAAGGCGACAAAAGTAG
Protein Sequence
MKLPVICRTCDSTDTDNLLKLATPSKKYPDKLFSDILAELTDINVDASASQKLPQCLCSSCTKKLMAAYCFVKQALAANELLMRHLKNATDCLQEAPMELCAEQHVEVKLETEDEEGGDNDVSITCSELPEPGERDVESKKSVDPLTMIETVKLEGEPPSVERPAEEEPASDFEDEDSLDNLPLNKRIQKWKARGMSVFKCHDCPRSFKRNEYLKRHEIRVHKPETHWFACSLCIRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVNLGTRPNLEPSELAELFYPDSKDLGEEQLIGLIRKDLASGIYQRFYSITNQSGYEMDLDSSETDSDMDVEHEDQQNTRRRKNRKGSYTCELCQQKFPRKYQLYDHQRQSHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGTKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQSGGGSRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSKEKLYSCGKCSYKFMWPENLEQHVRLQHSESASSHRTDGRRATATGDLDKDAGEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHTRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK