Basic Information

Insect: Drosophila bocki
Gene Symbol: -
Assembly: GCA_008042715.1
Location: VNJY01008303.1:12224-15279[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.9e-07 7.1e-05 22.9 3.1 1 23 205 228 205 228 0.95

2 17 3.4e-05 0.0025 18.1 0.2 1 23 235 257 235 257 0.97

3 17 0.19 14 6.3 0.1 2 23 289 310 288 310 0.94

4 17 4.7e-05 0.0034 17.6 2.3 1 23 398 421 398 421 0.97

5 17 0.22 16 6.1 0.6 1 19 428 446 428 449 0.93

6 17 0.061 4.4 7.8 6.4 1 23 458 480 458 480 0.95

7 17 6.3e-06 0.00045 20.4 0.4 1 23 487 510 487 510 0.97

8 17 0.00036 0.026 14.9 2.4 2 23 518 539 517 539 0.96

9 17 0.02 1.4 9.4 0.0 2 21 566 585 565 586 0.94

10 17 0.0073 0.53 10.7 2.6 1 23 635 658 635 658 0.98

11 17 0.0026 0.19 12.1 0.8 1 23 695 718 695 718 0.97

12 17 0.00012 0.0083 16.4 1.6 2 23 754 776 753 776 0.95

13 17 0.00076 0.055 13.8 0.2 1 23 790 812 790 812 0.95

14 17 1.4e-05 0.001 19.3 1.2 1 23 818 840 818 840 0.99

15 17 3e-07 2.2e-05 24.5 2.6 1 23 846 868 846 868 0.98

16 17 3.3e-05 0.0024 18.1 3.8 1 23 874 896 874 896 0.97

17 17 2.3e-05 0.0017 18.6 0.5 1 22 902 923 902 926 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.9e-07	7.1e-05	22.9	3.1	1	23	205	228	205	228	0.95
2	17	3.4e-05	0.0025	18.1	0.2	1	23	235	257	235	257	0.97
3	17	0.19	14	6.3	0.1	2	23	289	310	288	310	0.94
4	17	4.7e-05	0.0034	17.6	2.3	1	23	398	421	398	421	0.97
5	17	0.22	16	6.1	0.6	1	19	428	446	428	449	0.93
6	17	0.061	4.4	7.8	6.4	1	23	458	480	458	480	0.95
7	17	6.3e-06	0.00045	20.4	0.4	1	23	487	510	487	510	0.97
8	17	0.00036	0.026	14.9	2.4	2	23	518	539	517	539	0.96
9	17	0.02	1.4	9.4	0.0	2	21	566	585	565	586	0.94
10	17	0.0073	0.53	10.7	2.6	1	23	635	658	635	658	0.98
11	17	0.0026	0.19	12.1	0.8	1	23	695	718	695	718	0.97
12	17	0.00012	0.0083	16.4	1.6	2	23	754	776	753	776	0.95
13	17	0.00076	0.055	13.8	0.2	1	23	790	812	790	812	0.95
14	17	1.4e-05	0.001	19.3	1.2	1	23	818	840	818	840	0.99
15	17	3e-07	2.2e-05	24.5	2.6	1	23	846	868	846	868	0.98
16	17	3.3e-05	0.0024	18.1	3.8	1	23	874	896	874	896	0.97
17	17	2.3e-05	0.0017	18.6	0.5	1	22	902	923	902	926	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTTATGTGTCGCACCTGCGACTCCACGGACACTGACAATCTTCTCAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGCTGCTATCGGAGATTTTGATGGAGCTTACCGATATCCATGTGAACGCCAGTGGCACTCAGAAGCTGCCGCAGTGCTTgtgcagcagctgcaccaAGAAACTTATGGCTAGTTATTGCTTTGTGAAGCAGGCGCTGGCCGCCAATGAACTGCTGATGAAGCACCTAAAGAGCGGCTCCGCGCCAACCGCCAACGACTGTCTGCAGGAAGCGCCCATGGAGCTGTGCGCCGAGCAGCATGTGGAGGTCAAGATGGAGACGGAGGACGAGGAGTGTGGCGGCGATAAGGATGTTAGTATCAACTGCTCTGAGCTGCCAGAACCGGGCGAAATGGATGTGGAGAGCAAGAAGTCCGTGGATCCGCTGACCATGATTGAGACGGTGAAGCTGGAGGGCGAACCGCCAAGCATGGAACAGCCAGCGGAAGAAGAGCCCTCGTCGGACTTTGAGGATGAAGACTCCCTGGACAACCTGCCCCTGAATAAACGCATCCAAAAGTGGAAGGCCAGAAGTCTGTCCGTTTTCAAGTGCCACGATTGCCCTAGGAGTTTCAAGAGAAACGAGTACCTAAAGCGCCATGAAATCCGTGTCCACCAGCCGGAGACCCACTGGTTTGCCTGCTCCCTCTGCGTGCGCAAGTTTAGCCGCAGCGAAGCGCTCGAGGCTCACCTAAAGGTCCACAGAAACTCCAAGCGTTCGGCCAACATCAGTGAGCACAAAAAGGCCAAGGCAGTGGATCTGAATCTGTGCAAGCCGCATGGCTACAAGCTCATCGAGTGCATGATCTGCCAGAGTCAGTACAACAAGATTGCGGATCTTCGCAGGCATTTGGAAGAGCATCCGGATATTGTCAGCCTGGGTGTACGTCCAAATGTGGAGCCAAATGAGCTGGCGGAACTGTTTTATCCCGACTCCAAAGACCTGGACGAGGAGCAGTTGATCGTCTTAATCCGCAAGGATCTGGCTTCGGGCATTTATCAGCGTTTCTACTCGATAACCAATCAGAGTGGCTATGAAATGGATTTGGACAGCTCGGAGACGGACAGCGAGTTGGACGGTGAGCTTGAAGATCAGCAAAACAGGAGGCGGCGCAAGAATCGCTACACCTGCGAACTGTGTCAGCAAAAGTTTCCGCGGAAATATCAGCTCTATGATCACCAAAGGCAGAGCCACAGTTGGTCCGAGGCTCCGCATGTCTGTGGGCGGTGTGATGGACGCTTTGTTAGCCTGCAGTTGCTGAGGCATCACAACGAGTCGCAGTGCcgaaatgctcaaaaacgctTCCTTTGCCATAAATGTCCTTTGCGCTTTCGTTGGAAACACAATCTAAAGACACATTTCCGCGAGCATAGAATAACAAACCAAACCTTCGAGTGTCCCGAGTGCAAGCGGGtttttgacaaaaagaaatcccTCACCGTTCACCTGCTTAGCGTTCATGCCGAAGAATCCAAGCTCATACCTTGCCAGTGGTGTAGCCGCAAGTTCTATCGTCATGACTACCTGGTGAAGCATTTAAAGCGTCACGGGCTCAAGGAGCAGGACATTCCACTGGCCGAGACTTTGATAGCGGCCACATCGCGGCCCAATGGAACCAAGAGAATCACCTGCCGTATGTGCAATCTAAACTTTGAGCGGATTGTGGATTTGCGGGCCCACATCCAGCTGGAGTTGAAGCTCTCCTTGTCGCTACACCAAAGCTACGACTCGCCGCACAATTATTCAATTACAAACGAGTCTGGCTTTGAGTTGCAGCTGGAGGATTCGGAGACGGAGGATGAAATGCAGTCGAGCAGTGGCAGTCGTCATGTTTACATCTGTGAGTTGTGCAGCGTTCAATGCAAGCGGAAATTCGAAATGATTCAGCATCAGAGGACAATGCATCGTTTTGACAAAATGCCGCATGAATGCGATGATTGCATTTTCAAGTGTGTGTCCAAGAGCATAATGGATCACCACCGATTGGGGCAATGCAGCAGCAAGGACAAGATGTATACCTGCAGCAAATGCTCTTACAAATTCATGTGGCCCGAGAATCTAGAGCAGCACCTGCGACTTCAGCACAGCGAAACTTCTTCTACCAACAAACCCACAAGCAGCGAGGGCAGGCCACAGACTGGACCTGGTGACCTGGTCAAGGAAGCCGGCGAAGATGGTGTTCCCTTATTGCAGTGTCCTCACTGCGATCGCACTTACCAGATGAAGTCCCGCCTCAACAACCACATACGGGATGTCCATGTAAATGGCGATCGGAAGCGCAAGGAGGCCATCAAGCGTTTCTTGTGCTCTCTTTGCGGCAGGGAGACCCGTTCGGCAGCCGCTCTTGTTACCCATACCCGGCGTCACACCGGCGAAAAGCCTTTTAAATGCGATCAGTGTGAGATGGCCTTTCCCCGGCATTCGGAGTTGGCCTCCCATCGACGGATGCATACCGGTGAGAAGCCCTTCCACTGCACAGTCTGTGGCAAGGATTTTGCCCGCTCCGACAAGCTTAAGCGTCATATGCTCACCCACAGCGGTCTAAAGCCGCACAAGTGTACATACTGCGAGAAGAGCTATCGACAGGCCAAGGATTTGAAACTTCATCTCCAGCAGCACACGGGCGAGTGTCCGTTTGTGTGTGGCACTTGCGGCGAGCGATTCATACAGAGCAGCACGCTGGAGAAGCATCGTCTAATGCGACGCCACTTTGACGAAGTGGAAGCCTGGCTAAGGCGtcaaaaatag
Protein Sequence: MKLPVMCRTCDSTDTDNLLKLATPSKKYPDKLLSEILMELTDIHVNASGTQKLPQCLCSSCTKKLMASYCFVKQALAANELLMKHLKSGSAPTANDCLQEAPMELCAEQHVEVKMETEDEECGGDKDVSINCSELPEPGEMDVESKKSVDPLTMIETVKLEGEPPSMEQPAEEEPSSDFEDEDSLDNLPLNKRIQKWKARSLSVFKCHDCPRSFKRNEYLKRHEIRVHQPETHWFACSLCVRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLGVRPNVEPNELAELFYPDSKDLDEEQLIVLIRKDLASGIYQRFYSITNQSGYEMDLDSSETDSELDGELEDQQNRRRRKNRYTCELCQQKFPRKYQLYDHQRQSHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGTKRITCRMCNLNFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQSSSGSRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSKDKMYTCSKCSYKFMWPENLEQHLRLQHSETSSTNKPTSSEGRPQTGPGDLVKEAGEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGRETRSAAALVTHTRRHTGEKPFKCDQCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00531787;
80% Identity: -