Basic Information

Insect: Drosophila tsacasi
Gene Symbol: -
Assembly: GCA_018904565.1
Location: JAEIHY010008022.1:15069-18284[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.2e-06 0.00022 21.8 3.8 1 23 204 227 204 227 0.96

2 17 3.4e-05 0.0034 18.1 0.2 1 23 234 256 234 256 0.97

3 17 0.19 19 6.3 0.1 2 23 288 309 287 309 0.94

4 17 4.6e-05 0.0046 17.6 2.3 1 23 400 423 400 423 0.97

5 17 0.22 22 6.1 0.6 1 19 430 448 430 451 0.93

6 17 0.06 6 7.8 6.4 1 23 460 482 460 482 0.95

7 17 6.2e-06 0.00062 20.4 0.4 1 23 489 512 489 512 0.97

8 17 0.00035 0.035 14.9 2.4 2 23 520 541 519 541 0.96

9 17 0.023 2.3 9.1 0.2 2 21 568 587 567 588 0.94

10 17 0.0072 0.72 10.7 2.6 1 23 637 660 637 660 0.98

11 17 0.014 1.4 9.9 0.5 1 23 697 720 697 720 0.96

12 17 0.00011 0.011 16.4 1.6 2 23 754 776 753 776 0.95

13 17 0.019 1.9 9.4 0.1 1 23 790 812 790 812 0.95

14 17 1.6e-05 0.0016 19.1 1.0 1 23 818 840 818 840 0.99

15 17 2.9e-07 2.9e-05 24.5 2.6 1 23 846 868 846 868 0.98

16 17 3.3e-05 0.0033 18.1 3.8 1 23 874 896 874 896 0.97

17 17 2.3e-05 0.0023 18.6 0.5 1 22 902 923 902 926 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.2e-06	0.00022	21.8	3.8	1	23	204	227	204	227	0.96
2	17	3.4e-05	0.0034	18.1	0.2	1	23	234	256	234	256	0.97
3	17	0.19	19	6.3	0.1	2	23	288	309	287	309	0.94
4	17	4.6e-05	0.0046	17.6	2.3	1	23	400	423	400	423	0.97
5	17	0.22	22	6.1	0.6	1	19	430	448	430	451	0.93
6	17	0.06	6	7.8	6.4	1	23	460	482	460	482	0.95
7	17	6.2e-06	0.00062	20.4	0.4	1	23	489	512	489	512	0.97
8	17	0.00035	0.035	14.9	2.4	2	23	520	541	519	541	0.96
9	17	0.023	2.3	9.1	0.2	2	21	568	587	567	588	0.94
10	17	0.0072	0.72	10.7	2.6	1	23	637	660	637	660	0.98
11	17	0.014	1.4	9.9	0.5	1	23	697	720	697	720	0.96
12	17	0.00011	0.011	16.4	1.6	2	23	754	776	753	776	0.95
13	17	0.019	1.9	9.4	0.1	1	23	790	812	790	812	0.95
14	17	1.6e-05	0.0016	19.1	1.0	1	23	818	840	818	840	0.99
15	17	2.9e-07	2.9e-05	24.5	2.6	1	23	846	868	846	868	0.98
16	17	3.3e-05	0.0033	18.1	3.8	1	23	874	896	874	896	0.97
17	17	2.3e-05	0.0023	18.6	0.5	1	22	902	923	902	926	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTAATGTGTCGAACCTGCGACTCCACGGACACCGACAATCTTCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGAGAAGCTGCTCTCGGAGATTTTGACCGAGCTAACCGATATCCATGTGGACGCGAGTGGCACTCAAAAGCTGCCGCAGTGCTTGTGTAGCAGCTGCACCAAGAAACTAATGGGTGCATATTGTTTCGTGAAGCAGGCGCTGGTCGCCAACGAACTGTTGATGGGGCACTTGAAGAACGGCTCTGCACCGTCCGCCACCGACTGCCTACAGGAGGCGCCCATGGAGCTGTGCGCCGAGCAGCATGTGGAGGTCAAGATGGAGACGGAGGACGAGGAGTGTGGCGGCAACGATGTTAGTATCACCTGCTCCGACCTGCAAGAATCGGGCGAACGGGATGTGGAGAGTAAAAAGTCCGTGGATCCACTGACCATGATTGAGACGGTGAAACTGGAGGGGGAACCGCCAAACTTGGAGAGGCCGGTGGAAGAAGACCCAACCTCCGATTTTGATGATGAAGACTCCCTGGATAACCTGCCCCTGAATAAGCGCATCCAAAAGTGGAAGTCTAGAAGAATGCCCGTTTTCAAGTGCCACGAGTGCCCAAGGAGTTTCAAGAGAAACGAGTACCTAAAGCGCCACGAAAGCCGTGTCCATCAGCCGGAGACCCACTGGTTCGCCTGCTCCCTCTGCGTTCGCAAGTTCAGCCGCAGCGAAGCCCTCGAGGCTCACCTCAAGGTGCACAGCAGGTCCAAGCGGTCGGCCAACATCAGCGAGCACAAGAAGGCCAAGGCGGTGGATCTGAATCTGTGCAAGCCGCACGGCTACAAGCTCATCGAGTGCATGATCTGCCAGAGCCAGTACAACAAGATTGCGGATCTGCGGAGGCACTTGGAAGAGCATCCGGATATAGTCAGCCTGGGCGTTCGTCCTAATGTGCAGCCCCATGAGCTGGCGGAACTCTTTTATCCCGACTCCAAGGACATGGATGAAGAGCAGTTGATCGGTTTAATCCGCAAAGACCTGGCATCGGGCATCTATCAACGTTTCTACTCGATAACCAACCAGAGTGGGTACGAAATGGATCTGGACAGCTCGGAGACGGACAGCGATGCGGACGGTGAACCAGAGGATCAGCAGAACAAGCGGCGGCGCAAGAACCGCAGGGGTAGCTACACCTGCGAACTGTGCCAGCAGAAGTTTCCGCGGAAATATCAGCTATATGATCACCAACGGCAGAGCCACAGCTGGTCCGAGGCTCCGCATGTCTGCGGACGGTGTGATGGACGCTTTGTCAGCCTGCAACTGCTGCGGCATCACAACGAGTCGCAGTGCCGAAATGCACAGAAGCGTTTCCTCTGCCACAAGTGCCCGCTGCGCTTTCGGTGGAAACACAATCTAAAGACCCATTTCCGCGAGCATAGGATTACAAACCAAACCTTCGAGTGCCCCGAGTGCAAGCGGGTCTTTGACAAAAAGAAGTCCCTCACCGTTCACCTGCTCAGCGTCCATGCCGAGGAATCAAAGCTCATACCCTGCCAGTGGTGCAGTCGCAAGTTCTACCGGCATGACTATCTGGTGAAGCATCTGAAGCGCCATGGCCTCAGGGAGCAGGACATTCCACTGGCCGAGACCTTGATAGCGGCCACTTCGAGGCCGAATGGAACGAAGCGAATCACCTGCCGGATGTGCAATCTACACTTCGAGCGGATTATGGATCTGCGGGCTCACATCCAGCTGGAGCTGAAGCTGTCATTGTCGCTCCACCAGAGCTACGACTCGCCGCACAATTATTCGATCACTAACGAGTCCGGCTTCGAGCTGCAGCTGGAGGATTCGGAGACGGAGGACGAGATGCAGTCGAGCAGCGGCGGTCGTCACGTTTACATCTGCGAGCTGTGCAGTGTGCAGTGCAAGCGGAAATTTGAAATGATCCAGCATCAGAGGACAATGCATCGATTCGACAAAATGCCGCATGAATGCGACGACTGCATCTTCAAGTGTGTGTCCAAGAGCATCATGGATCATCATCGGCTGGGACAGTGCAGCAGCAAGGAGAAGATGTACTCGTGCAGCAAGTGCTCCTACAAGTTCATGTGGCCCGAGAACCTGGAGCAGCACGCGCGACTGCAGCACAGCGAATCCTCCCCCATCAGCAATCCCATTGGCGACGCCAGCCGGACTGGACCCGGTGATCTGGATAAGGATGCCGGCGAAGATGGGATACCATTGTTGCAGTGCCCGCATTGCGATCGCACCTACCAGATGAAGTCCCGGCTGAATAATCACATCCGGGATGTTCATGTCAACGGCGATCGCAAGCGCAAGGAGGCAATCAAGCGTTTCCTGTGCTCCCTGTGCGGCATGGAGACCGGATCGGCAGCCGCCCTTGTAACGCACACGCGTCGCCACACCGGTGAGAAGCCCTTTAAGTGCGATCTGTGCGAGATGGCCTTTCCCAGACACTCGGAGTTGGCCTCCCATCGCCGGATGCACACCGGCGAGAAGCCATTCCACTGCACAGTCTGCGGCAAGGATTTCGCCCGCTCCGACAAGCTCAAGCGCCACATGCTCACGCACAGCGGTCTGAAGCCGCACAAGTGTACGTACTGCGAGAAGAGCTATCGGCAGGCCAAGGATCTGAAGCTCCATCTGCAGCAGCACACCGGCGAGTGTCCGTTTGTGTGCGGCACCTGCGGCGAACGATTTATACAGAGCAGCACTCTGGAGAAGCACCGCCTGATGCGACGTCACTTTGACGAAGTGGAAGCCTGGCCAAGGCGTCTGAAATAA
Protein Sequence: MKLPVMCRTCDSTDTDNLLKLATPSKKYPEKLLSEILTELTDIHVDASGTQKLPQCLCSSCTKKLMGAYCFVKQALVANELLMGHLKNGSAPSATDCLQEAPMELCAEQHVEVKMETEDEECGGNDVSITCSDLQESGERDVESKKSVDPLTMIETVKLEGEPPNLERPVEEDPTSDFDDEDSLDNLPLNKRIQKWKSRRMPVFKCHECPRSFKRNEYLKRHESRVHQPETHWFACSLCVRKFSRSEALEAHLKVHSRSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLGVRPNVQPHELAELFYPDSKDMDEEQLIGLIRKDLASGIYQRFYSITNQSGYEMDLDSSETDSDADGEPEDQQNKRRRKNRRGSYTCELCQQKFPRKYQLYDHQRQSHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLREQDIPLAETLIAATSRPNGTKRITCRMCNLHFERIMDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQSSSGGRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSKEKMYSCSKCSYKFMWPENLEQHARLQHSESSPISNPIGDASRTGPGDLDKDAGEDGIPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETGSAAALVTHTRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWPRRLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00531787;
80% Identity: -