Dbir006899.1
Basic Information
- Insect
- Drosophila birchii
- Gene Symbol
- -
- Assembly
- GCA_008042755.1
- Location
- VNKA01006433.1:40594-43645[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.7e-05 0.0014 19.1 7.1 1 23 199 222 199 222 0.96 2 17 3.5e-05 0.0029 18.1 0.2 1 23 231 253 231 253 0.97 3 17 0.2 16 6.3 0.1 2 23 285 306 284 306 0.94 4 17 3.1e-05 0.0025 18.3 3.3 1 23 397 420 397 420 0.97 5 17 0.23 19 6.1 0.6 1 19 427 445 427 448 0.93 6 17 0.063 5.1 7.8 6.4 1 23 457 479 457 479 0.95 7 17 4.4e-06 0.00036 20.9 0.4 1 23 486 509 486 509 0.97 8 17 0.00037 0.03 14.9 2.4 2 23 517 538 516 538 0.96 9 17 0.017 1.4 9.6 0.1 2 21 565 584 564 585 0.94 10 17 0.0075 0.61 10.7 2.6 1 23 635 658 635 658 0.98 11 17 0.0027 0.22 12.1 0.8 1 23 695 718 695 718 0.97 12 17 0.00012 0.0096 16.4 1.6 2 23 749 771 748 771 0.95 13 17 0.0026 0.21 12.2 0.1 1 23 785 807 785 807 0.95 14 17 1.7e-05 0.0014 19.1 1.0 1 23 813 835 813 835 0.99 15 17 3.1e-07 2.5e-05 24.6 2.6 1 23 841 863 841 863 0.98 16 17 3.4e-05 0.0028 18.1 3.8 1 23 869 891 869 891 0.97 17 17 2.4e-05 0.0019 18.6 0.5 1 22 897 918 897 921 0.90
Sequence Information
- Coding Sequence
- ATGAAGCTGCCGGTAATGTGTCGCACCTGCGACTCCACGGACACCGACAATCTTCTTAAGCTGGCCACGCCCTCGAAAAAGTATCCGGAGAAGCTGCTCTCGGACATTTTGATGGAGCTCACCGACATCCATGTGGAGGCGAGTGGCAGCCAGAAGTTGCCACAATGCTTGTGCAGTAGCTGCACCAAGAAACTAATGGCAAGTTATTGCTTTGTAAAGCAGGCGCTGGCCGCCAACGAAATGCTGATGAAGCACTTGAAGAACACCACCGATTGCCTGCAGGAGGCGCCTATGGAGCTGTGCGCCGAGCAGCATGTGGAGGTCAAAATGGAGACGGAGGACGAGGACTGTGGCGACAAGGATGTTGGTATTCACTGCTCTGAGCTGCCTGAAACGGGAGAACGAGATGTGGAGAGCAAAAAGTCCGTGGATCCACTGACAATGATTGAGACGGTGAAGCTGGAGGGAGAGCCGCCAAGCGTGGAGAGGCCTCGGGAAGAAGAGCCCACCTCGGACTTGGATGATGAAGACTCCCTGGACAACCTGCCCCTGAATAAACGCATTCAAAAGTGGAAGGCTCGAAGGCTGTCGGTTTTCAAGTGCCACGATTGCCCCAGAAGTTTCAAGCGAAGCGAGTACCTAAAGCGCCATGAAAGCCGCTGTCATCAGCCGGAGACGGAGACCCAGTGGTTCGCCTGCTCCCTTTGCGTTCGCAAATTCAGCCGCAGCGAAGCCCTCGAGGCTCACCTCAAGGTGCACCGAAACTCCAAGCGATCGGCCAACATAAGCGAGCACAAGAAGGCCAAGGCGGTGGATCTGAATCTCTGCAAGCCGCATGGCTACAAGCTCATCGAGTGCATGATCTGCCAGAGTCAGTACAACAAGATTGCCGATCTGCGTAGGCACTTGGAAGAGCATCCGGATATTGTCAGCCTGGGCGTTCGACCGAATGTGGAGCCCAATGAGCTGGCCGAGCTGTTTTATCCCGACTCCAAGGACCTGGATGAGGAGCAGTTGATTTGCTTGATTCGCAAGGATCTGGCAGCTGGAATTTATCAGCGTTTCTACTCGATAACCAATCAGAGTGGCTACGAAATGGATCTGGACAGCTCGGAGACGGACAGCGATGTGGATGGTGACCCCGAGGATCAGCAGAACAAGAGGCGACGCAAGAACCGCAGGGGTAGCTACACCTGCGAATTGTGTCAGCAGAAGTTTACGCGAAAATATCAACTGTACGATCACCAACGGCAGAGCCACAGTTGGTCCGAGGCTCCGCATGTCTGCGGGCGGTGTGATGGACGCTTTGTAagcctgcagctgctgcgtcATCACAACGAATCGCAGTGCCGGAATGCACAGAAGCGCTTCCTTTGCCACAAATGTCCGCTGCGCTTCCGATGGAAACACAATCTGAAGACTCATTTCCGCGAGCATAGGATTACAAACCAAACCTTTGAGTGTCCCGATTGCAAGCGTGTCTTTGACAAAAAGAAATCCCTCACCGTTCACCTGCTCAGCGTCCATGCCGAGGAATCCAAGCTGATACCCTGCCAGTGGTGCAGTCGCAAGTTCTATCGGCATGATTACCTGGTGAAGCATTTGAAGCGACATGGACTCAAGGAGCAGGACATTCCACTGGCCGAGACCCTAATAGCGGCCACTTCGCGGCCAAATGGCGCCAAGAGAATCACCTGCCGGATGTGCAATCTGCACTTTGAACGCATTGTGGATCTCCGAGCTCATATCCAGCTAGAGCTGAAGCTGTCCTTGTCGCTGCACCAGAGCTACGACTCGCCGCATAATTATTCCATAACAAATGAATCCGGTTTCGAGTTGCAGCTGGAGGATTCGGAAACAGAGGATGAGATGCAGTCAAGTCAAGGCGGCAGTCGTCATGTTTACATCTGTGAGCTGTGCAGTGTGCAGTGCAAGCGGAAATTCGAGATGATCCAACATCAGAGGACAATGCATCGTTTCGACAAAATGCCGCACGAGTGCGATGATTGCATCTTCAAGTGTGTGTCCAAGAGCATCATGGATCACCATCGGCTGGGGCAGTGCAGCAGCAAAGAGAAGCTGTACACCTGCAGCAAGTGCTCCTACAAGTTCATGTGGCCCGAGAACCTGGAGCAGCACCTGAGACTGCAgcacagtgaagcttcctCCGCCAGCAATCCTATACCACAGACTGCAACCGGTGACCTCGATAAGGAGGCCGGCGAAGATGGTGTACCCTTGTTGCAGTGTCCGCATTGCGATCGCACCTACCAAATGAAATCCCGCCTCAACAATCACATTCGAGATGTCCACGTAAATGGCGATCGCAAGCGCAAGGAGGCCATTAAGCGTTTCCTGTGCTCTCTGTGCGGCATGGAGACTCGATCAGCGGCTGCCCTTGTCACGCACACCCGACGACACACCGGGGAGAAGCCCTTCAAGTGCGATCTGTGTGAGATGGCCTTTCCCAGGCATTCGGAATTGGCCTCCCATCGACGGATGCACACCGGCGAGAAGCCATTCCACTGCACCGTTTGCGGCAAGGATTTCGCTCGCTCGGACAAGCTTAAGCGCCACATGCTCACCCACAGCGGCCTGAAGCCGCACAAGTGTACGTACTGCGAGAAGAGCTATCGCCAGGCCAAGGATCTGAAGCTacacctgcagcagcacaCCGGCGAATGTCCCTTCGTTTGCGGCACTTGCGGCGAACGATTCATACAGAGCAGCACGCTGGAGAAGCATCGCCTGATGCGACGACACTTTGACGAAGTGGAAGCCTGGCTGAGGCGTCAGAAATAG
- Protein Sequence
- MKLPVMCRTCDSTDTDNLLKLATPSKKYPEKLLSDILMELTDIHVEASGSQKLPQCLCSSCTKKLMASYCFVKQALAANEMLMKHLKNTTDCLQEAPMELCAEQHVEVKMETEDEDCGDKDVGIHCSELPETGERDVESKKSVDPLTMIETVKLEGEPPSVERPREEEPTSDLDDEDSLDNLPLNKRIQKWKARRLSVFKCHDCPRSFKRSEYLKRHESRCHQPETETQWFACSLCVRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLGVRPNVEPNELAELFYPDSKDLDEEQLICLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDVDGDPEDQQNKRRRKNRRGSYTCELCQQKFTRKYQLYDHQRQSHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPDCKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGAKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQSSQGGSRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSKEKLYTCSKCSYKFMWPENLEQHLRLQHSEASSASNPIPQTATGDLDKEAGEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHTRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00581676;
- 90% Identity
- iTF_00531787;
- 80% Identity
- -