Basic Information

Insect: Drosophila merina
Gene Symbol: -
Assembly: GCA_035047645.1
Location: JAWNPH010000002.1:8896806-8899847[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.8e-06 0.00016 22.1 3.2 1 23 202 225 202 225 0.96

2 17 0.00067 0.061 14.0 0.1 1 23 232 254 232 254 0.97

3 17 0.19 17 6.3 0.1 2 23 286 307 285 307 0.94

4 17 0.00015 0.014 16.0 1.4 1 23 396 419 396 419 0.97

5 17 0.22 20 6.1 0.6 1 19 426 444 426 447 0.93

6 17 0.022 2 9.2 5.3 1 23 456 478 456 478 0.95

7 17 6.3e-06 0.00057 20.4 0.4 1 23 485 508 485 508 0.97

8 17 0.00035 0.032 14.9 2.4 2 23 516 537 515 537 0.96

9 17 0.018 1.6 9.5 0.0 2 21 564 583 563 584 0.94

10 17 0.0041 0.37 11.5 2.7 1 23 633 656 633 656 0.98

11 17 0.13 12 6.8 0.5 1 23 693 716 693 716 0.92

12 17 0.00011 0.01 16.4 1.6 2 23 747 769 746 769 0.95

13 17 0.0027 0.24 12.1 0.1 1 23 783 805 783 805 0.95

14 17 4.7e-06 0.00043 20.8 1.0 1 23 811 833 811 833 0.99

15 17 3e-07 2.7e-05 24.6 2.6 1 23 839 861 839 861 0.98

16 17 3.3e-05 0.003 18.1 3.8 1 23 867 889 867 889 0.97

17 17 2.3e-05 0.0021 18.6 0.5 1 22 895 916 895 919 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.8e-06	0.00016	22.1	3.2	1	23	202	225	202	225	0.96
2	17	0.00067	0.061	14.0	0.1	1	23	232	254	232	254	0.97
3	17	0.19	17	6.3	0.1	2	23	286	307	285	307	0.94
4	17	0.00015	0.014	16.0	1.4	1	23	396	419	396	419	0.97
5	17	0.22	20	6.1	0.6	1	19	426	444	426	447	0.93
6	17	0.022	2	9.2	5.3	1	23	456	478	456	478	0.95
7	17	6.3e-06	0.00057	20.4	0.4	1	23	485	508	485	508	0.97
8	17	0.00035	0.032	14.9	2.4	2	23	516	537	515	537	0.96
9	17	0.018	1.6	9.5	0.0	2	21	564	583	563	584	0.94
10	17	0.0041	0.37	11.5	2.7	1	23	633	656	633	656	0.98
11	17	0.13	12	6.8	0.5	1	23	693	716	693	716	0.92
12	17	0.00011	0.01	16.4	1.6	2	23	747	769	746	769	0.95
13	17	0.0027	0.24	12.1	0.1	1	23	783	805	783	805	0.95
14	17	4.7e-06	0.00043	20.8	1.0	1	23	811	833	811	833	0.99
15	17	3e-07	2.7e-05	24.6	2.6	1	23	839	861	839	861	0.98
16	17	3.3e-05	0.003	18.1	3.8	1	23	867	889	867	889	0.97
17	17	2.3e-05	0.0021	18.6	0.5	1	22	895	916	895	919	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTAACCTGTCGCACCTGCGACTCCACGGACACCGACAATCTTCTGGAACTGGCCACGCCCTCGAAGAAATATCCGGACAAACTGATTTCCGATATTTTAGCGGAGCTAACTGACATAAATGTGGATGCCACTGCTGGTCGGAAAGTGCCACAAGCCCTGTGCCTAGCCTGCACCAAGAAGCTAATGGGTGCGTATTGCTACGTAAAGCAGGCGCTGGTCGCCAACGAATTACTGATGAAGCACCTCAAGAGGGTCAGCGCCACCGATTGCTTACTGGAAACGCCCATGGAGCTGTGTGCCGAGCAACACGTGAAGGTTAAGATGGAAACAGAGGAGGACGAGGATATGGGTGCTAACGATGTGAGATTAACTGGCCCGGAACTAATCGAAACGGAGGAACAGGAGGTGGATAACAAAAAGTCTGTTGATCCGCTGACCATGATAGAGTCAGTTAAGATAGAGACGGAACCGTCTAGCGTGGACTTTGTAGTGGAAGGAGAATTCATTACGGATCTAGAGGATGAAGACTCCCTGGATAACTTACCCTTGTTCAAGAGAATTGAAAAATGGAAAGAAGGCAGAAAGTCGTCGTTTAACTGCCACGATTGCCCGCGGAGTTTCAAGCAAGCAGAGTACCTAAAGAGACACCAGATCCGTTTCCACAAGCCCGAAGTCCACTGGTACGCCTGCTCCCTCTGCATTCGAAAGTTCAGTAGCAGCGAAGCTCTAGAGGCTCATCTAAAAGTTCACCGAAACTCCAAGCGATCTTCCAACGTAAGCGAGCACAAGAAGGCCAAGACTGTGGATCTGAATCTCTGCAAGCCGCACGGCTACAAGCTAATCGAGTGTATGATATGTCAGAGCCAGTACAATAAGATTGCGGATCTGCGACGGCATTTGGAGGAGCATCCTGACATCAACAGCCTGAGCTTGCGTCCCAATATGGAGGCCAACGAACTGGCGGAACTGTTTTATCCCGACTCGAAACACTTGGACGAAGATCGGTTGATTAGTTTAATTCAAAAGGATCTCGCCTCAGGCATTTACCAGCGATTCTATTCTATAACCAATCAGAGTGGCTATGAGATGGATCTGGACAGTTCCGAGACGGAAAGTGATTTCGATGGAGAACCCGAGGATTCATATAAGCGAAAGAAATACCGCAAGCCAAACTACATCTGCGAACTTTGTCAGCAAAAGTTTCCGCGAAAATACCTTTTGTACGACCACCAACGACAAACTCACAATTGGTCAGATGCTCCTCATGTCTGCGGGCGGTGCGATGGTCGCTTTGTGAGTCTCCAGCTGCTGAGGCATCATAACGAGTCGCAGTGTAGGAATGCGCAGAAGAGGTTTTTGTGCCACAAATGTCCGCTGCGCTTTCGTTGGAAACATAATTTGAAAGCCCATTTCCGAGAGCACAGAATTACGaATCAAACCTTCGAGTGTCCCGAATGCAAAAGGGTCTTTGACAAAAAGAAGTCTCTCACGGTCCACCTGCTTAGTGTTCATGCTGAAGAGTCCAAACTGATTCCGTGTCAGTGGTGTAGTCGTAAATTTTATCGTCATGACTATTTGGTGAAGCATCTGAAGAGGCATGGCCTCAAGGAGCAAGACATACCACTAGCCGAGACTTTGATTTCGGCCACATCGCGCCCGAACGGAGCGAAACGAATAACCTGCCGGATGTGCAACATAAACTTTGACCGCATTGTGGATCTACGAGCTCACATCCAACTAGAGCTGAAACTATCTCTTTCTCTGCATCAAAGTTACGATTCCCCGCACAATTATTCGATAACCAATGAGTCTGGTTTCGAGCTGCAGCTAGAAGACTCGGAAACGGACGATGAGATTTCTGCAGGCTCCAGCAATCGTCCTGTTTACGTGTGCGAGCTGTGCAGCGTCCAGTGCAAGCGGAAGTTTGAAATGATTCAGCACCAGAGAACAATGCACAGGTTTGATAAAATGCCACACGAGTGCGATGGATGCATTTTTAAGTGTGTGTCCAAGAGCATCATGGATCACCATCGTCTGGGGCAGTGCAATAGTTCGGAGAAGAAGCACGCATGCGGCAAGTGCTCCTACAAATTCATGTGGCCTGAGAATCTCGAGCAACACTTGCTTCTGCAACACAGTAATCCAGCTACCAGCAATTCTCCTGGAGTCAAGCGTCACAGTGGTGACTTGGACAAGGAGGCGTCTGAGGACGGGGTGCCGCTGCTGCAGTGTCCACATTGCGATCGCACCTACCAAATGAAGTCGCGATTGAACAACCATATCCGTGATGTCCATGTCAATGGTGATCGTAAGCGGAAAGAGGCAGTAAAGCGCTTCCTCTGCTCGCTTTGTGGGATGGAAACGCAGTCCGCTGCAGCTCTGGTCACCCACATGCGACGGCACACTGGTGAAAAGCCCTTTAAATGCGATTTGTGTGACATGGCCTTCCCACGTCACTCAGAACTAGCATCGCATCGTCGAATGCACACCGGCGAGAAGCCATTCCATTGTACAGTTTGCGGCAAGGACTTCGCCCGCTCCGACAAGCTGAAGCGCCACATGCTCACTCACAGTGGCCTCAAACCGCACAAGTGCACCTACTGCGAGAAGAGCTATCGCCAGGCCAAGGACCTTAAGCTGCACTTGCAGCAACACACGGGGGAATGTCCTTTTGTTTGTGGGACCTGCGGCGAGCGCTTTATCCAGAGCAGTACATTGGAGAAACATCGCCTAATGCGGCGACACTTCGATGAGGGTGAAGCGTGGGTTAGGGGTCAAAAATAG
Protein Sequence: MKLPVTCRTCDSTDTDNLLELATPSKKYPDKLISDILAELTDINVDATAGRKVPQALCLACTKKLMGAYCYVKQALVANELLMKHLKRVSATDCLLETPMELCAEQHVKVKMETEEDEDMGANDVRLTGPELIETEEQEVDNKKSVDPLTMIESVKIETEPSSVDFVVEGEFITDLEDEDSLDNLPLFKRIEKWKEGRKSSFNCHDCPRSFKQAEYLKRHQIRFHKPEVHWYACSLCIRKFSSSEALEAHLKVHRNSKRSSNVSEHKKAKTVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDINSLSLRPNMEANELAELFYPDSKHLDEDRLISLIQKDLASGIYQRFYSITNQSGYEMDLDSSETESDFDGEPEDSYKRKKYRKPNYICELCQQKFPRKYLLYDHQRQTHNWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKAHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLISATSRPNGAKRITCRMCNINFDRIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETDDEISAGSSNRPVYVCELCSVQCKRKFEMIQHQRTMHRFDKMPHECDGCIFKCVSKSIMDHHRLGQCNSSEKKHACGKCSYKFMWPENLEQHLLLQHSNPATSNSPGVKRHSGDLDKEASEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAVKRFLCSLCGMETQSAAALVTHMRRHTGEKPFKCDLCDMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEGEAWVRGQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00481666;
80% Identity: -