Basic Information

Insect: Drosophila kanapiae
Gene Symbol: -
Assembly: GCA_008042475.1
Location: VNJM01001954.1:190269-193321[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-06 8.1e-05 22.9 3.1 1 23 200 223 200 223 0.95

2 17 3.5e-05 0.0028 18.1 0.2 1 23 230 252 230 252 0.97

3 17 0.2 16 6.3 0.1 2 23 284 305 283 305 0.94

4 17 4.8e-05 0.0038 17.6 2.3 1 23 397 420 397 420 0.97

5 17 0.23 18 6.1 0.6 1 19 427 445 427 448 0.93

6 17 0.063 5 7.8 6.4 1 23 457 479 457 479 0.95

7 17 6.4e-06 0.00051 20.4 0.4 1 23 486 509 486 509 0.97

8 17 0.00036 0.029 14.9 2.4 2 23 517 538 516 538 0.96

9 17 0.017 1.3 9.6 0.1 2 21 565 584 564 585 0.94

10 17 0.0075 0.6 10.7 2.6 1 23 634 657 634 657 0.98

11 17 0.25 20 5.9 0.3 1 23 694 717 694 717 0.93

12 17 0.00012 0.0094 16.4 1.6 2 23 750 772 749 772 0.95

13 17 0.0026 0.21 12.2 0.1 1 23 786 808 786 808 0.95

14 17 1.7e-05 0.0014 19.1 1.0 1 23 814 836 814 836 0.99

15 17 3.1e-07 2.4e-05 24.5 2.6 1 23 842 864 842 864 0.98

16 17 3.4e-05 0.0027 18.1 3.8 1 23 870 892 870 892 0.97

17 17 2.4e-05 0.0019 18.6 0.5 1 22 898 919 898 922 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-06	8.1e-05	22.9	3.1	1	23	200	223	200	223	0.95
2	17	3.5e-05	0.0028	18.1	0.2	1	23	230	252	230	252	0.97
3	17	0.2	16	6.3	0.1	2	23	284	305	283	305	0.94
4	17	4.8e-05	0.0038	17.6	2.3	1	23	397	420	397	420	0.97
5	17	0.23	18	6.1	0.6	1	19	427	445	427	448	0.93
6	17	0.063	5	7.8	6.4	1	23	457	479	457	479	0.95
7	17	6.4e-06	0.00051	20.4	0.4	1	23	486	509	486	509	0.97
8	17	0.00036	0.029	14.9	2.4	2	23	517	538	516	538	0.96
9	17	0.017	1.3	9.6	0.1	2	21	565	584	564	585	0.94
10	17	0.0075	0.6	10.7	2.6	1	23	634	657	634	657	0.98
11	17	0.25	20	5.9	0.3	1	23	694	717	694	717	0.93
12	17	0.00012	0.0094	16.4	1.6	2	23	750	772	749	772	0.95
13	17	0.0026	0.21	12.2	0.1	1	23	786	808	786	808	0.95
14	17	1.7e-05	0.0014	19.1	1.0	1	23	814	836	814	836	0.99
15	17	3.1e-07	2.4e-05	24.5	2.6	1	23	842	864	842	864	0.98
16	17	3.4e-05	0.0027	18.1	3.8	1	23	870	892	870	892	0.97
17	17	2.4e-05	0.0019	18.6	0.5	1	22	898	919	898	922	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTAATTTGTCGCACCTGCGACTCCACGGACACCGACAATCTTCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGAAAAGCTGCTCTCGGAGATTTTGGCGGAGCTAACTGATATCCATGTGGATGCGAGTGGCAGTCAGAAGCTGCCGCAGTGCttgtgcagcagctgcaccaaGAAACTAATGGGTGCATATTGCTTCGTGAAGCAGGCGCTGGCCGCCAACGAACTGCTGATGAAGCACTTGAAGACCGCCACCGACTGTCTGCAGGAGGCGCCCATGGAGCTGTGCGCGGAGCAGCATGTGGAGGTCAAGATGGAGACGGAGGACGAGGAGTGTGGCGACAACGATGTAAGCATCACCTGCTCCGAGCTGCCAGAGCCGGGCGAGCGGGATGTGGAGAGCAAGAAGTCCGTGGATCCCCTAACTATGATCGAGACGGTGAAGCTGGAGGGGGAACCGCCAAGTGTGGAGAGGCCGGCGGAAGAAGAGCCCGCCTCGGActtcgatgatgatgatgaCTCCCTGGATAACCTGCCCCTGAATAAGCGCATCCAAAAGTGGAAGGCCCGGAGGATGTCCGTTTTCAAATGCCACGATTGCCCGAGGAGTTTCAAGAGAAACGAATACCTGAAACGCCACGAAATCCGCGTCCACCAGCCGGAGACGCCATGGTTCGCCTGCTCCCTCTGCGTTCGCAAGTTCAGCCGCAGCGAAGCCCTCGAGGCTCACCTGAAGGTCCACAGGAACTCCAAGCGATCGGCCAACATCAGCGAGCACAAGAAGGCCAAGGCGGTGGATTTGAATCTCTGCAAGCCGCACGGCTACAAGCTCATCGAGTGCATGATCTGCCAGAGCCAGTACAACAAGATAGCGGATCTGCGACGGCACTTGGAGGAGCATCCAGATATTGTCAGTCTGGGCGTTCGTCCAAATCTAGAGCCGAATGAGCTGGCGGAACTGTTTTATCCCGACTCCAAGGACCTGGGCGAGGAGCAGTTGATTGGTTTAATCCGCAAGGATCTGGCGGCGGGCGTTTATCAACGTTTCTACTCGATAACCAACCAGAGTGGCTACGAAATGGATCTGGACAGCTCGGAAACGGACAGCGATCTAGATGGTTGTGAGCCCGAGGATCAGCAGAACAAGAGGCGGCGGAAGAATCGCAAAGGCAGCTACACCTGCGAACTCTGCCAGCAGAAGTTTCCGCGAAAATATCAGCTGTACGATCATCAGCGGCAGAGCCACAGTTGGTCCGAGGCTCCGCATGTGTGCGGCCGTTGCGATGGACGCTTTGTcagcctgcagctgctgcggcatcACAACGAGTCGCAGTGCCGGAACGCCCAAAAGCGCTTTCTCTGTCACAAATGCCCGCTGCGCTTCCGGTGGAAACACAATTTGAAAACGCATTTCCGCGAGCATAGAATTACAAACCAAACCTTCGAGTGTCCCGAGTGCAAGCGAGTCTTCGACAAAAAGAAGTCCCTCACCGTTCACCTGCTCAGCGTGCATGCCGAGGAATCAAAGCTCATACCTTGTCAGTGGTGCAGCCGCAAGTTCTATCGACATGACTACCTGGTAAAGCATCTAAAGCGCCATGGATTGAAGGAACAGGACATTCCCCTAGCCGAGACCTTGATAGCGGCCACCTCGCGGCCAAATGGCACGAAGAGAATCACCTGCCGCATGTGTAATCTTCACTTTGAGCGCATAGTGGACCTCCGTGCCCATAtccagctggagctgaagctgtcCTTGTCGCTGCACCAGAGCTACGATTCGCCACACAATTATTCAATCACCAATGAGTCTGGTTTCGAGCTGCAGCTAGAGGATTCGGAGACGGAGGATGAGTTGCAGTCGAGTGGGGGAAGCCGTCATGTTTACATCTGCGAGCTGTGCAGCGTGCAGTGCAAGCGGAAATTCGAGATGATCCAGCACCAGAGGACAATGCATCGATTTGACAAAATGCCGCATGAATGCGATGATTGCATCTTCAAGTGTGTGTCCAAGAGCATCATGGACCACCACCGTTTGGGCCAGTGCAGCAGCAAAGACAAGCTGTACTCCTGCGGCAAGTGCTCCTACAAGTTCATGTGGCCCGAGAACATGGAACAGCACGTGCAACTGCAGCACAGCAAATCTTCGTCTAACAGTTCCACAGGCGGCAGGCCACGGACAGCAGCCGGAGATCTGGATAAGGAAGCCGGCGAAGATGGTGTGCCCTTGTTGCAGTGTCCGCATTGCGACCGCACCTACCAGATGAAGTCCCGCCTGAACAACCACATACGGGATGTGCATGTAAACGGCGATCGAAAGCGCAAGGAGGCCATCAAACGTTTCCTCTGCTCCCTGTGCGGCATGGAAACGAGATCGGCCGCCGCCCTTGTCACCCACACCCGTCGTCACACGGGCGAGAAGCCCTTCAAGTGCGATCTGTGCGAGATGGCCTTTCCCAGGCACTCGGAGCTGGCCTCACATCGCAGGATGCACACCGGTGAGAAGCCATTCCACTGCACTGTTTGCGGCAAGGATTTCGCCCGCTCCGACAAGCTCAAGCGCCACATGCTCACCCACAGCGGCCTGAAGCCGCACAAGTGTACATACTGCGAGAAGAGCTACCGCCAGGCGAAGGATCTAAAGCTACACCTCCAGCAGCACACCGGCGAGTGTCCGTTTGTGTGCGGGACCTGCGGCGAGCGCTTTATACAGAGTAGCACGCTGGAGAAGCACCGCCTGATGCGGCGCCACTTTGACGAAGTGGAAGCCTGGCTGAGGCGTCAAAAATAA
Protein Sequence: MKLPVICRTCDSTDTDNLLKLATPSKKYPEKLLSEILAELTDIHVDASGSQKLPQCLCSSCTKKLMGAYCFVKQALAANELLMKHLKTATDCLQEAPMELCAEQHVEVKMETEDEECGDNDVSITCSELPEPGERDVESKKSVDPLTMIETVKLEGEPPSVERPAEEEPASDFDDDDDSLDNLPLNKRIQKWKARRMSVFKCHDCPRSFKRNEYLKRHEIRVHQPETPWFACSLCVRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLGVRPNLEPNELAELFYPDSKDLGEEQLIGLIRKDLAAGVYQRFYSITNQSGYEMDLDSSETDSDLDGCEPEDQQNKRRRKNRKGSYTCELCQQKFPRKYQLYDHQRQSHSWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGTKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDELQSSGGSRHVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRLGQCSSKDKLYSCGKCSYKFMWPENMEQHVQLQHSKSSSNSSTGGRPRTAAGDLDKEAGEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETRSAAALVTHTRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00531787;
80% Identity: -