Dfuy001976.1
Basic Information
- Insect
- Drosophila fuyamai
- Gene Symbol
- -
- Assembly
- GCA_018153365.1
- Location
- JAECXW010000393.1:8590612-8593640[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.5e-05 0.0011 19.2 1.6 1 23 202 225 202 225 0.97 2 17 0.00048 0.037 14.5 0.2 1 23 232 254 232 254 0.97 3 17 0.19 15 6.3 0.1 2 23 286 307 285 307 0.94 4 17 0.00064 0.049 14.1 4.6 1 23 394 417 394 417 0.96 5 17 0.23 18 6.1 0.6 1 19 424 442 424 445 0.93 6 17 0.062 4.8 7.8 6.4 1 23 454 476 454 476 0.95 7 17 4.4e-06 0.00034 20.9 0.4 1 23 483 506 483 506 0.97 8 17 0.00036 0.028 14.9 2.4 2 23 514 535 513 535 0.96 9 17 0.022 1.7 9.3 0.2 2 21 562 581 561 582 0.94 10 17 0.0074 0.58 10.7 2.6 1 23 631 654 631 654 0.98 11 17 0.019 1.5 9.4 0.6 1 23 691 714 691 714 0.94 12 17 0.00012 0.0091 16.4 1.6 2 23 747 769 746 769 0.95 13 17 0.0027 0.21 12.1 0.1 1 23 783 805 783 805 0.95 14 17 1.2e-05 0.00092 19.5 0.9 1 23 811 833 811 833 0.99 15 17 3e-07 2.4e-05 24.6 2.6 1 23 839 861 839 861 0.98 16 17 3.4e-05 0.0026 18.1 3.8 1 23 867 889 867 889 0.97 17 17 2.4e-05 0.0018 18.6 0.5 1 22 895 916 895 919 0.90
Sequence Information
- Coding Sequence
- ATGAAGCTGCCGGTGATTTGTCGCACCTGCGACTCTACGGACACCGACAACCTTCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGCTGCTCTCGGAAATACTGTGCGAGCTGACCGAAATCAATATGGATACCACCGGAAGCCAGAAACTTCCTCAGTGTTTGTGCAGTGGCTGCACCAAGAAATTGATGGGTGCATATTGCTATGTAAAGCAGGCGCTGGCCGCCAATGAGTTGTTAATGAAGCACCTAAGAAATGGGGCTGCTCCAACGGCCACCGATTGCCTGCAGGAGACGCCAATGGAGCTATGTGCCGAGCAGCATGTGGAGGTCAAAATAGAGACCGAGGACGAGGACTGTGGTGATAACGATGTCAGCATTACTTGCTCCGAACTGCCGGAACCGGACGATATGGATGTAGAGAGCAAGAAGTCCGTGGATCCTCTGACCATGATTGATACGGTTAAGCTGGAAACGGGACTTCCAAGCATTGAAAAACCAACGGATGACGTTTCGGACTTCGAAGACGAGGACTCCCTGGACAACCTGCCTCTGTATAAGCGCATTCAAAAGTGGAAGATAGGTAGAAAGCCTATATTCAAATGCCAGGACTGCCCGAGAAGCTTCAAGCGAATCGAGTTCCTTAAAAGACATGAGAACCGCGTCCATAAGGAGGAATCACTCTCATTTGCATGTTCTCTCTGCATTCGCAAGTTTAGCCGCAGCGAAGCCCTTGAGGCGCACCTGAAAGTCCACCGAAACTCCAAGCGATCGGCGAACATAAGCGAGCATAAGAAGGCGAAGGCGGTGGATTTGAATCTCTGCAAGCCGCACGGCTACAAACTAATCGAGTGCATGATTTGCCAAAGCCAGTACAACAAGATTGCCGATCTGCGGCGACATTTAGAGGAGCATCCCGAGATAGTCAGCCTGTGTGGCCGGCCAAATGTGGAGCCACAAGAACTTTTTTATCCCGACTCCAAGGACCTTGGCGAGGAGCAATTAATAAGCTTGATTCGAAAGGATTTGGCGGCAGGCATTTATCAGCGTTTCTATTCCATAACCAACCAGAGTGGCTACGAAATGGACCTGGATAGTTCCGAGACGGACAGTGATCTGGACGGAGATCCTGAGGATAAACAAAAAAGTGGAAAGAAAAGCCGTAAAAGCAGCTACTGCTGCGAACTATGCCAGCAGAAATTCCCGCGAAAATATCAGTTATATGACCACCAGCGACAGACCCACACTTGGTCAGAAGCTCCTCATGTCTGCGGGCGGTGTGATGGACGCTTCGTGAGTCTGCAGCTACTGCGGCATCACAATGAGTCGCAGTGCAGGAATGCGCAGAAGCGGTTTCTTTGCCACAAATGTCCGCTTCGCTTTCGATGGAAACACAACCTTAAAACACATTTCCGCGAGCACAGGATTACAAACCAAACCTTTGAGTGTCCCGATTGCAAACGGGTCTTTGACAAAAAGAAATCGCTTACCGTTCATCTGCTCAGCGTACATGCAGAGGAATCGAAACTAATCCCCTGCCAGTGGTGCAGTCGCAAGTTCTACCGACACGACTACCTGGTAAAGCACCTAAAGCGGCACGGCCTTAGGGAGCAAGACATTCCGCTGGCCGAGACTTTGATAGCGGCCACCTCGCGGCCAAACGGAGCGAAACGCATCACCTGCCGCATGTGCAACTTGCACTTTGAACGTATCGTGGATCTGCGAACCCACATCCAGCTGGAGTTAAAGCTGTCCTTGTCTCTGCACCAGAGCTACGACTCACTACGCAATTACTCGATTACAAATGAGTCTGGGTTCGAACTGCAGCTGGAGGATTCGGAGACGGAGGACGAGATGCAGCCGGGCGGTGGAAGTCGTCCCGTTTATATTTGCGAGCTGTGTAGCGTGCAGTGCAAGAGGAAATTTGAAATGATCCAGCATCAGCGAACAATGCACCGCTTCGACAAAATGCCACATGAGTGCGATGACTGCATTTTCAAGTGTGTGTCCAAGAGTATCATGGATCACCACCGACAGGGCCAGTGCAGCAGTACAGAAAAAAAGCATCCTTGCAACAAGTGCTCCTACAAATTCATGTGGCCCGAGAATCTGGAACAGCACATTCTTCTGCAGCACAACGACTCGTCCGCCAGCAATCTGACTGGAATAAGGAGGTCGACAGGAACGGGTGACCTGGAAAAGGATGCCGCCGAGGATGAGGTTCCATTGCTGCAGTGCCCACACTGCGATCGCACCTACCAGATGAAGTCGCGTCTGAACAACCACATCCGTGATGTTCATGTTAACGGTGACCGTAAGCGCAAGGAAGCAATCAAGCGTTTCCTCTGCTCCCTTTGCGGCATGGAGACCCAATCCGCGGCGGCACTGGTGACCCATATGCGGCGCCACACAGGCGAGAAGCCGTACAAGTGCGATCTGTGCGAGATGGCCTTTCCCCGGCACTCGGAGCTGGCCTCGCACCGCCGAATGCACACCGGTGAGAAGCCATTCCACTGCACCGTCTGCGGCAAGGACTTTGCTCGCTCCGACAAGCTGAAACGACATATGCTTACCCACAGCGGCCTGAAACCGCACAAATGCACCTACTGCGAGAAGAGCTACCGCCAGGCCAAGGATCTAAAACTCCACCTGCAGCAGCACACCGGCGAATGTCCTTTCGTGTGCGGCACCTGCGGCGAGCGTTTCATCCAAAGCAGCACGCTGGAGAAGCACAGGCTGATGCGACGCCACTTCGACGAGGTGGAGGCGTGGTTGAGGCGCCAAAAATAG
- Protein Sequence
- MKLPVICRTCDSTDTDNLLKLATPSKKYPDKLLSEILCELTEINMDTTGSQKLPQCLCSGCTKKLMGAYCYVKQALAANELLMKHLRNGAAPTATDCLQETPMELCAEQHVEVKIETEDEDCGDNDVSITCSELPEPDDMDVESKKSVDPLTMIDTVKLETGLPSIEKPTDDVSDFEDEDSLDNLPLYKRIQKWKIGRKPIFKCQDCPRSFKRIEFLKRHENRVHKEESLSFACSLCIRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPEIVSLCGRPNVEPQELFYPDSKDLGEEQLISLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDPEDKQKSGKKSRKSSYCCELCQQKFPRKYQLYDHQRQTHTWSEAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECPDCKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLREQDIPLAETLIAATSRPNGAKRITCRMCNLHFERIVDLRTHIQLELKLSLSLHQSYDSLRNYSITNESGFELQLEDSETEDEMQPGGGSRPVYICELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQCSSTEKKHPCNKCSYKFMWPENLEQHILLQHNDSSASNLTGIRRSTGTGDLEKDAAEDEVPLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAIKRFLCSLCGMETQSAAALVTHMRRHTGEKPYKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVEAWLRRQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00581676;
- 90% Identity
- iTF_00604984;
- 80% Identity
- -