Basic Information

Insect: Drosophila santomea
Gene Symbol: -
Assembly: GCA_016746245.1
Location: NC:16940639-16943839[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 6.6e-06 0.00042 20.2 2.3 1 23 207 230 207 230 0.97

2 17 0.00035 0.022 14.8 0.1 1 23 237 259 237 259 0.97

3 17 0.18 12 6.3 0.1 2 23 291 312 290 312 0.94

4 17 6.4e-05 0.0041 17.1 2.1 1 23 402 425 402 425 0.97

5 17 0.21 14 6.1 0.6 1 19 432 450 432 453 0.93

6 17 0.059 3.7 7.8 6.4 1 23 462 484 462 484 0.95

7 17 1.9e-05 0.0012 18.8 0.7 1 23 491 514 491 514 0.97

8 17 0.00034 0.022 14.9 2.4 2 23 522 543 521 543 0.96

9 17 0.016 1 9.6 0.1 2 21 570 589 569 590 0.94

10 17 0.0077 0.49 10.6 3.1 1 23 639 662 639 662 0.98

11 17 0.14 8.9 6.6 0.4 1 23 699 722 699 722 0.92

12 17 0.00011 0.007 16.4 1.6 2 23 755 777 754 777 0.95

13 17 0.00033 0.021 14.9 0.1 1 23 791 813 791 813 0.95

14 17 1.6e-05 0.001 19.1 1.0 1 23 819 841 819 841 0.99

15 17 2.8e-07 1.8e-05 24.5 2.6 1 23 847 869 847 869 0.98

16 17 3.2e-05 0.002 18.1 3.8 1 23 875 897 875 897 0.97

17 17 2.2e-05 0.0014 18.6 0.5 1 22 903 924 903 927 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	6.6e-06	0.00042	20.2	2.3	1	23	207	230	207	230	0.97
2	17	0.00035	0.022	14.8	0.1	1	23	237	259	237	259	0.97
3	17	0.18	12	6.3	0.1	2	23	291	312	290	312	0.94
4	17	6.4e-05	0.0041	17.1	2.1	1	23	402	425	402	425	0.97
5	17	0.21	14	6.1	0.6	1	19	432	450	432	453	0.93
6	17	0.059	3.7	7.8	6.4	1	23	462	484	462	484	0.95
7	17	1.9e-05	0.0012	18.8	0.7	1	23	491	514	491	514	0.97
8	17	0.00034	0.022	14.9	2.4	2	23	522	543	521	543	0.96
9	17	0.016	1	9.6	0.1	2	21	570	589	569	590	0.94
10	17	0.0077	0.49	10.6	3.1	1	23	639	662	639	662	0.98
11	17	0.14	8.9	6.6	0.4	1	23	699	722	699	722	0.92
12	17	0.00011	0.007	16.4	1.6	2	23	755	777	754	777	0.95
13	17	0.00033	0.021	14.9	0.1	1	23	791	813	791	813	0.95
14	17	1.6e-05	0.001	19.1	1.0	1	23	819	841	819	841	0.99
15	17	2.8e-07	1.8e-05	24.5	2.6	1	23	847	869	847	869	0.98
16	17	3.2e-05	0.002	18.1	3.8	1	23	875	897	875	897	0.97
17	17	2.2e-05	0.0014	18.6	0.5	1	22	903	924	903	927	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTGATTTGTCGCACTTGCGACTCCACGGACACCGACAACCTTCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGTTGCTTTCGGAGATTTTGTGCGAGCTAACCGAAATCAATGTAAACAAACTGGATGCGACTGGCAGTCAGAAACTTCCGCAATGCTTGTGCAGCGGATGCACCAAGAAATTAATGGGCGCCTATTGCTATGTGAAGCAGGCGCTGGCCGCCAACGAACTTCTAATGAAGCATCTAAAGAACGGAGGTGCTCCATCGTCAACCGACTGCCTGCAGGAGGCGCCCATGGAGCTGTGTGCCGAGCAGCATGTGGAAGTGAAGCTGGAGACCGAGGATGAGGACTGTGGCGAAAACGATGTCACCATCACTTGCTCCGAGCTACCGGAACCGGACGAAATGGATATGGAGAGCAAAAAGTCCGTGGACCCTCTGACCATGATTGAGACTGTGAAACTGGAAATGGAGCCAAGGAGCGTTGAGAAACCAGCGGAAGACGATCAGTCATCGGACTTTGAAGATGAAGACTCCCTAGATAATTTGCCGCTGTATAATCGCATTCAAAAGTGGAAAACAGGAAGGAAGACTGTATATAAATGTCAGGATTGCCCGAGGAGTTTTAAACGATTCGACTTTCTAAAACGCCATGAAATGCGCGTTCATAAGCCAGAAGCTCGATTGTACGCCTGTTCACTTTGCATTCGCAAGTTCAGCCGCAGCGAAGCCCTCGAAGCGCACCTGAAAGTTCACCGGAATTCAAAACGATCGGCGAACATTAGCGAGCACAAGAAGGCAAAGGCCGTGGATGTGAATCTCTGCAAACCGCATGGGTACAAGCTTATTGAGTGCATGATTTGCCAGAGCCAATACAACAAGATTGCTGATCTACGACGACATTTGGAGGAGCACCCCGATATTAACAGTCTATGTGGTCGACCAAATATGGAGTCCCATGAGCTGGCGGAGCTGTTTTATCCCGATTCCAAGGACCTCAGTGAGGAGCAGGTAATCAACTTGATTCGCAAGGACCTGGCGGCAGGTATCTATCAGCGTTTCTATTCGATAACGAATCAAAGTGGCTACGAAATGGATCTGGACAGCTCGGAGACAGACAGCGATCTGGACGGGGATCCTGATGACCAGCAAAAGAGGCGAAAAAAGTCGCGCAAAGCCACCTACAGCTGCGAACTGTGCCAGCAAAAGTTCCCGCGAAAATATCAGCTTTATGACCACCAGCGACAGAGCCACAGTTGGTCAGACGCCCCTCATGTTTGCGGGCGATGTGATGGACGTTTTGTTAgtctgcagctgctgcggcaCCACAACGAGTCGCAGTGTAGGAATGCACAAAAACGATTTCTCTGTCACAAATGCCCGCTGCGCTTCCGCTGGAAACACAACCTGAAAACACACTTCCGCGAACACAGGATAATAAATCAAACCTTTGAATGTTCCGAGTGCAAACGTGTCTTTGACAAAAAGAAATCCCTCACCGTTCACCTGCTTAGCGTACATGCGGAGGAATCAAAGCTGATTCCCTGCCAGTGGTGCAGTCGCAAATTCTATCGGCACGACTACTTGGTCAAGCACCTGAAGCGCCACGGTTTGAAAGAGCAGGACATTCCCTTGGCAGAAACATTGATTGCTGCCACCTCTCGGCCAAACGGTGCAAAGCGCATTACCTGCCGCATGTGCAATCTGCATTTCGAGCGTATTGTTGATCTGCGCGCCCATATCCAGTTGGAGCTCAAGCTATCCCTGTCGCTACACCAGAGCTACGACTCTCCGCACAATTACTCGATAACAAACGAATCTGGCTTTGAACTGCAGCTCGAGGATTCGGAAACCGAGGACGAGATGCAGCCCGGTGCTGGCAGTCGACCCGTCTATATGTGCGAGCTGTGCAGCGTGCAGTGCAAGCGGAAGTTCGAAATGATCCAGCATCAACGGACGATGCATCGCTTTGACAAAATGCCACACGAATGCGACGACTGCATCTTTAAATGTGTCTCCAAGAGCATTATGGACCATCACCGGCAAGGCCAGTGTAGTAGTACAGAAAAGAAGCATCCATGCGGCAAGTGCTCCTACAAGTTCATGTGGCCAGAGAACTTAGAGCAGCATGTTCTTCTGCAACACAGCAAGTCTTCCGTTGGCAATCCAGCTGGCGTCAGACGCACGCCAGGTACCGGTGAACTGGAAAAGGATGCCACTGAGGACGGAGTGCCGCTGCTACAGTGTCCGCACTGCGATCGCACATACCAGATGAAGTCTCGCCTGAACAACCACATTCGCGATGTGCACATTAACGGCGACCGCAAGCGCAAGGAGGCTATCAAGCGCTTCCTCTGCTCCCTGTGCGGAATGGAGACGAGATCAGCTGCCGCCCTTGTCACACATATGCGACGCCACACTGGCGAGAAGCCCTTTAAGTGCGATCTGTGCGAGATGGCCTTTCCCCGCCACTCAGAGCTGGCCTCGCACCGCCGGATGCACACCGGCGAGAAGCCATTCCACTGCACCGTCTGCGGCAAGGACTTTGCACGCTCAGATAAGCTTAAGCGCCATATGCTCACGCACAGCGGTTTAAAGCCGCACAAATGCACATACTGCGAGAAGAGCTACCGCCAGGCCAAGGACCTCAAGCTTCATCTCCAGCAGCACACCGGAGAATGTCCTTTTGTGTGCGGCACCTGTGGCGAGCGCTTCATCCAGAGCAGCACGCTGGAGAAGCATCGGTTGATGCGGCGTCACTTCGACGAGGTGGAGACGTGGCTGAGGCGCCAAAAGTAA
Protein Sequence: MKLPVICRTCDSTDTDNLLKLATPSKKYPDKLLSEILCELTEINVNKLDATGSQKLPQCLCSGCTKKLMGAYCYVKQALAANELLMKHLKNGGAPSSTDCLQEAPMELCAEQHVEVKLETEDEDCGENDVTITCSELPEPDEMDMESKKSVDPLTMIETVKLEMEPRSVEKPAEDDQSSDFEDEDSLDNLPLYNRIQKWKTGRKTVYKCQDCPRSFKRFDFLKRHEMRVHKPEARLYACSLCIRKFSRSEALEAHLKVHRNSKRSANISEHKKAKAVDVNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDINSLCGRPNMESHELAELFYPDSKDLSEEQVINLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDPDDQQKRRKKSRKATYSCELCQQKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRIINQTFECSECKRVFDKKKSLTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSRPNGAKRITCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETEDEMQPGAGSRPVYMCELCSVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQCSSTEKKHPCGKCSYKFMWPENLEQHVLLQHSKSSVGNPAGVRRTPGTGELEKDATEDGVPLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSELASHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFVCGTCGERFIQSSTLEKHRLMRRHFDEVETWLRRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581676;
90% Identity: iTF_00604984;
80% Identity: -