Dpse001772.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pseudotalamancana
Gene Symbol
zfh1
Assembly
GCA_037075185.1
Location
JBAMCK010000131.1:1255496-1259567[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.7e-05 0.0019 18.6 1.0 1 23 150 172 150 172 0.97
2 15 0.00082 0.057 13.9 1.2 3 23 180 200 178 200 0.94
3 15 8.9e-05 0.0062 16.9 0.1 1 23 353 375 353 375 0.98
4 15 0.00031 0.021 15.2 0.9 1 23 381 403 381 403 0.98
5 15 3.4e-05 0.0023 18.3 2.2 1 23 434 457 434 457 0.95
6 15 0.00013 0.0091 16.4 0.5 1 23 479 501 479 501 0.95
7 15 0.014 0.98 10.0 1.5 1 23 507 530 507 530 0.97
8 15 0.026 1.8 9.2 0.4 3 19 539 555 538 556 0.95
9 15 0.00015 0.011 16.2 5.6 1 23 565 587 565 587 0.97
10 15 0.04 2.8 8.6 1.2 2 23 593 614 592 614 0.96
11 15 9e-06 0.00063 20.0 1.0 1 23 623 645 623 645 0.98
12 15 0.001 0.072 13.6 0.1 3 23 653 673 651 673 0.97
13 15 5.5e-05 0.0038 17.6 0.5 1 23 679 701 679 702 0.95
14 15 0.052 3.6 8.2 0.4 1 23 712 734 712 734 0.97
15 15 0.0016 0.11 13.0 0.3 1 23 1247 1269 1247 1269 0.98

Sequence Information

Coding Sequence
ATGAACAATCAGGATTATGGCGGCATCCAATGGATACAGCAGCATGCATCTGCGGTTGACTCCGAAACTGATTTGCTGGAAAACAGCGCTGCTGACAATGAGGTGACTGCCGCCTACTTGGTAAATGGCAATGCAACCGACGAGGATCTCGACCATATGGCGGCCGAAAATCTCATTTTCATGGCGCGTGATGGTCAGCTGAGCGAGATTATTGCCGCCAACGAAGCCGGCGGCGGCACTGTATTAATCACGGACAGCGGGACCGTTGCTTATGCCGAGTCATATGAGGATGATGCGCAGGTGGTCACTGAGGAGATTATTACCGATGACTGGGTGCAGCATCAGGGGGCCGAGCGGGTGGAAATTGCCGCGGAACAAATTGCGGGCAACAATAGCTCACAGGAGCTTTTGGACATGGAGCAGGATGAGTATACGGCGTTACGACCCTATCCGTGTGATTTCTGTAGCCGTCGTTTTCGCAAGAAAGCCAGCCTCAACAATCACATGCTGGCGCATCAGAATGATCGCCCACACCTCTGTAAATTGTGCGGCGCACGGTTTTCACGGCGTGCTGAGCTCATCAGTCACTTCAAGGCGCATGCCGAGGCGCAGGTTGCGGCAGATCAAGCGGCCGCTATTAAATtcgagccgcagcagcaacaacgccAAGTGGATGATCATTTCTACGAGCAGGAATGGCCATTGTATCAGGTACAGGAAGAAGATCAAGTGCAGGAGCAGATGCATGAaatggagcaggagcagctggtGGTGCCACAAGCCAGTTATGCAGAGGTCAGCGCTGTGCCAGGGCCAACAGCTACACGCGGTCGCATAAGCCGCCTAAAGCCCAAGGAAGAGAGCACTCAATACATTGTGATTGCCGAAAAGCAGACAACTGAAGATTTGCAAGAGTATATGGATTGCGAAGAGTTGCAGCCAACATTGGAGGGCAGTACGTCAACCTCAACCGAAGCGTCGCATATGGCAGTCAGCAACCCAGTCGCCGAAACGACCCAGCCTGAGCGCTTCCCGGTGATAGACGACAGCAAGCCTTTTGTGTGCCAGCAGTGCGGATTAGCATTTGCTCGCGAGAAGGCCCTCGTCTCGCATATCAAGAATCATCGCATGGACTCACCCTTCGAATGCAACCAGTGTCAGGAGATGTTCTGGGATAATTACAGCCTGCAGGAACATCAGAAGACGCATCAGTTCGAGGAGAGTAATTCGGAGTACGATCCGGCATCGGCCGGCGAGGAAAGCGTCAGCGAATCGGAACCGGATCAGCTTTACGGTGAATTCTACTGTAGCGAGTGCGGCATTTCTTTTCACAGGCAGGATCTGTTGCGGCGCCATgcaaagcagcagcacaagcacTCCACGGACATGGAGAGCGGCGCCGATGTTGAACTCGATAATGCCAAAGAAGCAGCACACAGTTGTCATACATGTGGCAAATCATTTCCCAGTGCACTGGAGCTGCTCGCCCATGCCGAGGTTCATGCTCGCTTTCCTCCCTTCAAATGCGTCCTGTGCGGTCTTAGCTTTTACGAGGAACAGGCTATCAAGCGGCATTTACACACGCGTCATCCGCACGAGCTGAAGCCCAATTCGTGCGTGCTGTGCGGCAAGGAGTGTCGGGATCGGAAAGCACTTATAAAGCACGCCTGGGATCATTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGGAAGAACTTTCACAACAAGGCGCGTCTGAAGCGGCACATGGCCTCGCATCGGGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTCCCCGACGGACGCACACTTTCTAACCATCGCCATTCGCACAGCACCACATCGCCCGGCAAGCTGTTTCCCTGCCACGAGTGCGGCAAGACCTTCGGCTCACGCAGCTCCCAGCAGATTCATGTGCGCATCCACACCGGGGAACGACCGTATGGATGTCGCTACTGCTGGAAGGCGTTCGCCGACGGCGGCACTCTGCGCAAGCACGAACGCATTCACACTGGCGAGAAGCCTTACGCCTGCTCAGTGTGTCCGCGTGCCTTCAATCAGCGCGTCGTATTGCGTGAGCACATTCGTTCCCATCACTCGGGGCTGGATGCAGTCCGTGGCACCTATCACTGCACTGTGTGCTCGGCCGATTTGTCCTCATCCAATGAGCTTATTCAGCATCTCATCCAGCACAGTGACACAAACACCGCCAAACAGCGACAACCGATTACCGGCCCGCGGAAGTACAAGCGACGCAGGAAACTGCAACCACATGAGATAGCCCACATGCGAGCGGAACACAAGGATGGCGAGGACTATGCCAGCGATATTGAATTCTGTGACTTGGATGTGGAAAATGTGGATGAGCTCCTGGACAGGGCGGACACATTGCCaatcaaaaaggaaaagcgcaAGCGACCGGCTGCAAACCAAGCTAAATCCGTAAGCAACGGAGccactgaaaacaaaaactccgCCAATAGCACCTGGGATGAAAAGTTCCTTCAAACCAATAGCAACGGCAACATTACCAACGTCGACGATGCCTACAAGAGCATCTTCCAAATTGACTCAATGGTGGTGGTTAATGATACAACACTGCCGCCCATGACCACAGCCAGCAGTACGCCAAGTGCCGCGAAGTCGCGACGCGGCGGCAAGCAGACACAGACGCAAACACAGGCCGAGAACGGCGACAAGTCAGGAGGAGCAGCGGCGACAACCGCAACTGGTGAGGAGTCTGGCAAATCTAGCACCGttagcagtcgcagcagcagcagaaagaagTCCAGCAAGGCGGCTAAGAGTGCAGCCGCATCCAGCAGCTCGCGCCCCCGCATGATCCATACGGAAAAGTCACGTGTGCCGCCGGAGAATGCATCGAAAAAATCACGTGGTCGCAGCTACATCACGCGCACCAGCACAAGTGAGAGCACTCAGTTGGAGCTGGTCAAGTCGAGTGGAGTGTCCAGTTCGCGCATTGTCGACGACTACGAGATTATATCACCTGCCACCCAGCCCCCAAATCAGATCAGTTCCAGCCCGCTGCACATCAAGcaagagcaggagcagcagcagcagcgcgtcCAGCTAATGTACGATGACACGCATCTGCTGATGCAAGCGGCAATGCTGCGCGAGAAGACCTACGACAAGTTCAATCCGAGCATTGTCAATGATCTCGAAGAGATTTTGCGTAGTCCCCTGAAGCATGATCGGAATGCGCGTCTGCGTTTCACCAGCGAATCGTCGACAACGCCACAGTTTCTGCCCGAGGAGGAGCAGAACCTCATTAAGATCGAGCCCACTTCGCCGGATCTGCGTGAAATGGTGGAGAGCCAACAGCGTGTTACTGCCACAGGACAaaccgccacgcccacatcatcgtcatcctcgTCGTCCGCAGCGCGCACATCGCGTCATCTGCGACAGCTCACTGCCAACTCGAGCAGCCGAGCGGGAACGAAACGCAACAGTGGGAAAAACGCAACCGCCTCCAGCGCCAAGACACCGAGCACATCCTCAACAGAAGCCGTCAGTAAAGCGGCCAGCAATTCGTATCTCAGCTATGGCGTGGACTCCTACAATGTGAGTGTGGCGGCGAGTGCCAACTCTTCGGATGTCAGCTCCGGTTTCTTCTCCATCTCCGAGGTGGTATCCGCTGCCCATGCCGCCGATGCAGCGGCCAAGGCAGCCGCGGCCAGCAAAACGGAGCGCCGGACCCGCTGCTTTGAGTGCGAAATGTGCTCATCCATATTTCCCGATCGCGCCCAGCTGCTGGagcacatgcatatacacatcTAA
Protein Sequence
MNNQDYGGIQWIQQHASAVDSETDLLENSAADNEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANEAGGGTVLITDSGTVAYAESYEDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADQAAAIKFEPQQQQRQVDDHFYEQEWPLYQVQEEDQVQEQMHEMEQEQLVVPQASYAEVSAVPGPTATRGRISRLKPKEESTQYIVIAEKQTTEDLQEYMDCEELQPTLEGSTSTSTEASHMAVSNPVAETTQPERFPVIDDSKPFVCQQCGLAFAREKALVSHIKNHRMDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEESVSESEPDQLYGEFYCSECGISFHRQDLLRRHAKQQHKHSTDMESGADVELDNAKEAAHSCHTCGKSFPSALELLAHAEVHARFPPFKCVLCGLSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCSADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGEDYASDIEFCDLDVENVDELLDRADTLPIKKEKRKRPAANQAKSVSNGATENKNSANSTWDEKFLQTNSNGNITNVDDAYKSIFQIDSMVVVNDTTLPPMTTASSTPSAAKSRRGGKQTQTQTQAENGDKSGGAAATTATGEESGKSSTVSSRSSSRKKSSKAAKSAAASSSSRPRMIHTEKSRVPPENASKKSRGRSYITRTSTSESTQLELVKSSGVSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRVQLMYDDTHLLMQAAMLREKTYDKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTATGQTATPTSSSSSSSAARTSRHLRQLTANSSSRAGTKRNSGKNATASSAKTPSTSSTEAVSKAASNSYLSYGVDSYNVSVAASANSSDVSSGFFSISEVVSAAHAADAAAKAAAASKTERRTRCFECEMCSSIFPDRAQLLEHMHIHI