Basic Information

Insect: Drosophila colorata
Gene Symbol: zfh1
Assembly: GCA_035041545.1
Location: JAWNLD010000482.1:2300333-2304382[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.8e-05 0.0018 18.6 1.0 1 23 150 172 150 172 0.97

2 15 0.0035 0.23 12.0 1.2 3 23 180 200 178 200 0.94

3 15 9.4e-05 0.0061 16.9 0.1 1 23 342 364 342 364 0.98

4 15 0.00032 0.021 15.2 0.9 1 23 370 392 370 392 0.98

5 15 3.5e-05 0.0023 18.2 2.2 1 23 423 446 423 446 0.95

6 15 0.002 0.13 12.7 1.3 1 23 466 488 466 488 0.95

7 15 0.0019 0.12 12.8 0.4 1 23 494 517 494 517 0.98

8 15 0.027 1.8 9.2 0.4 3 19 526 542 525 543 0.95

9 15 0.00016 0.011 16.2 5.6 1 23 552 574 552 574 0.97

10 15 0.042 2.7 8.6 1.2 2 23 580 601 579 601 0.96

11 15 9.5e-06 0.00062 20.0 1.0 1 23 610 632 610 632 0.98

12 15 0.0011 0.07 13.6 0.1 3 23 640 660 638 660 0.97

13 15 0.00015 0.0098 16.3 0.9 1 23 666 688 666 689 0.95

14 15 0.23 15 6.3 0.2 1 23 699 721 699 721 0.96

15 15 0.0016 0.11 13.0 0.3 1 23 1251 1273 1251 1273 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.8e-05	0.0018	18.6	1.0	1	23	150	172	150	172	0.97
2	15	0.0035	0.23	12.0	1.2	3	23	180	200	178	200	0.94
3	15	9.4e-05	0.0061	16.9	0.1	1	23	342	364	342	364	0.98
4	15	0.00032	0.021	15.2	0.9	1	23	370	392	370	392	0.98
5	15	3.5e-05	0.0023	18.2	2.2	1	23	423	446	423	446	0.95
6	15	0.002	0.13	12.7	1.3	1	23	466	488	466	488	0.95
7	15	0.0019	0.12	12.8	0.4	1	23	494	517	494	517	0.98
8	15	0.027	1.8	9.2	0.4	3	19	526	542	525	543	0.95
9	15	0.00016	0.011	16.2	5.6	1	23	552	574	552	574	0.97
10	15	0.042	2.7	8.6	1.2	2	23	580	601	579	601	0.96
11	15	9.5e-06	0.00062	20.0	1.0	1	23	610	632	610	632	0.98
12	15	0.0011	0.07	13.6	0.1	3	23	640	660	638	660	0.97
13	15	0.00015	0.0098	16.3	0.9	1	23	666	688	666	689	0.95
14	15	0.23	15	6.3	0.2	1	23	699	721	699	721	0.96
15	15	0.0016	0.11	13.0	0.3	1	23	1251	1273	1251	1273	0.98

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACAGCAGCACGCCTCGGCTGTCGACTCCGAGACGGATATGCTGGAAGGCGGCGCTGCCGACGGCGAGGTGACCGCCGCCTATCTGGTGAACGGGAACGCGACCGACGAGGATCTCGACCATATGGCGGCCGAGAATCTGATCTTTATGGCGCGCGACGGCCAGCTGAGCGAGATCATTGCCGCCAACGAGGCGGGCGGCGGCACAGTTTTAATCACGGATAACGGCACCGTTGCCTACGCGGAGTCCTTCGACGAGGACGCCCAGGTGGTCACCGAGGAGATAATCACCGACGACTGGGTGCAGCACCAGGGCGCCGAGCGAGTGGAAATCGCGGCCGAGCAAATTGCGGGCAACAACAGCTCGCAGGAGCTGCTGGACATGGAGCAGGACGAGTACACGGCGCTGCGCCCCTATCCGTGCGACTTCTGCAGCCGGCGCTTCCGCAAGAAGGCCAGCCTTAACAATCACATGCTGGCGCACCAGAACGATCGTCCGCATCTCTGCAAGCTGTGCGGCGGACGGTTCTCGCGGCGCGCCGAGCTGATCAGCCACTTCAAGGCGCACGCCGAGGCGCAAGTGGCAGCggatgccgctgctgcggcggcggcaatcAAATTCGAACCGCAGCAGCGACAAATCGACGATCATTTCTACGAGCAATGGCCGCTCTATCAGGAGCAGGAACAGGAAGAGGagcaggcacaggcacagcaACTGGTGCAGGAGCAGCCGGCTGTGACACAGGCCAGCTATGCAGCGGCGCCCACAGCGGCACGCGGTCGTATCAGTCGCCTCAAGCCCAAGGAGGAGAGCACCCAGTACATTGTGCTCGCCGAAAAGCAAGCGACATCCGAGGTGGATGAGCTGCATCAGTACATGGATTGCGAGGAGCTGCCAACAGCGGGCAACGCGTCGAGCGGGGAGAGCGGCCATGCCGCTGAGGCTGCGCAGCCGCTGCGCTTTCCGGTGCTGGACGAGAGCAAGCCCTTCGTGTGCCAGCAGTGCGGCCTGGCGTTCGCGCGCGAGAAGGCGCTCGTTTCGCACATCAAGAATCATCGCGTAGACTCGCCCTTTGAGTGTAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGCCTGCAGGAGCATCAGAAGACGCATCAGTTTGAGGAGAGCAACTCGGAGTACGAACCGGCGTCGGCGGGCGAGGATAGCGCCAGCGAATCCGAACCGGACCAGCTGTACGGCGACTTCTACTGCAGCGAGTGCGGCATTTCATTTCACAGGCAGGACCTGCTCCGGCGCCACgccaagcagcagcacaaGGATGCGGAGGGCACCGACAACGCTGAAGCCGGCGACGATGCCAAAGATGCGGCACACTGTTGCCACACGTGCGGCAAAGGCTTTCCCAGCGCACTGGAGCTGCTCGCCCATGCCGAGATCCATGCCCGTTTCCCGCCATTCAAATGCGTCCTGTGCGGTGTCAGCTTCTACGAGGAGGAAGCCATCAAGCGGCACCTGAAGACGCGCCATCCGCACGAGCTGAAGCCCAACTCGTGCGTGCTGTGCGGCAAGGAGTGCCGTGACCGCAAGGCACTGATCAAGCACGCCTGGGACCATTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCGCGGCTCAAGCGACACATGGCCTCGCACCGGGACAAGTCCGTGGTGTGCGAGGTCTGCCACGAGGAGTTCCCAGACGGACGCACTCTCTCCAATCACCGGCACTCGCACAGTACCACGTCGCCGGGCAAGATGTTCCCCTGCCACGAGTGCGGCAAGACCTTTGGCTCGCGCAGCTCCCAGCAGATCCACGTGCGCATCCACACGGGCGAACGTCCGTACGGCTGTCGCTACTGCTGGAAGGCGTTCGCCGACGGCGGCACACTGCGCAAGCACGAGCGCATCCACACCGGCGAGAAGCCCTACGCCTGCTCCGTGTGCACGCGCGCCTTCAACCAGCGCGTGGTGCTGCGCGAGCACATACGCTCCCATCACTCGGGCCTGGACGCGGTGCGCGGCACTTACCACTGCACCGTCTGCGCGGCGGACTTGTCCTCGTCCAACGAGCTCATCCAGCACCTAATCCAGCACAGCGACACGAACACGGCCAAGCAGCGACAGCCCATTACCGGGCCGCGCAAATACAAGCGCCGCAGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCGGGCAACAAGGACGGCGAGGACTACGCAAGTGACATTGAATATTGCGATCTAGATGTGGAGAACGTGGACGATCTGCTCGACCGCGTCGAGCCGTTGCCCAGCAAAAAGGAGAAGCGCAAGCGGGCTGCTGCAAATCCAGCCAAAGCCGTGGCCAATGGCGCCGCTGCGTCCTCCGGCTCGGTGAAGTCGGCCAACAGCAGCTCGGAACGTCTGTGGGATGAGAAATTtattggcaatggcaacgtGGCCACTGACGATGCCTACAAGAGCTTCTTTCAGATTGACTCCTTGGTGGTGGTCAACGACACCACCCTGCCGCCCGTTAGCTCAGTCAGCGGGGCGGCCAGTGGCGCCAGGTCGCGGCGCAGCGGCAAGCAGGCGGCAGCGGGCAGCAGTGACAAGCTGGCGGCAGCTGGCGAGGAGTCTGCCAAGTCCGGCgtcagcagtcgcagcagcaggagaAAAACGAGCAAGGCGGCCAAGAGTACAGGcacagctggagcagcagccgctgcagctggagcaaCAGTCACCGCCAGCAGTTCGCGTCCCCGTATGATACACACGGAAAAGTCACGTGTGCCGCTGGAGAATCCGGCGAAGAGGTCACGGGGTCGCAGCTACGTCACGCGCACCAGCACCAGCGAGAGCAGCCAGCTGGGCCTGGTCAAGGCGGGCGGCGGCGTTGCCAGCTCGCGCATTGTCGATGACTACGAGATTATATCACCTGCCACACAGCCGCCCAACCAGATCAGCTCCAGTCCGCTGCACATcaagcaggagcaggagcaactgcagcagcagcagcatcatcatcatcatcatcatcataatcaccagcagcagcagcagcgcgtgCAGCTCATGTACGACGACACGCATCTGCTGATCGATGCGAAGACCTTCGAGAAGTTCAATCCGAGCATTGTCAACGATCTCGAGGAGATACTGCGCAGTCCGCTCAAGCACGATCGCAATGCGCGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCTCAGTTTCTGCCCGAGGAGGAGCAGAATCTGATTAAAATCGAGCCGACGTCGCCGGATCTGCGGGAGATGGTGGAGAGCCAGCAGCGTGTAACTGCCACGGGACacacggccacgcccacatcctcatcatcgtcgtcgtcggcggaGGGCGCACTTCGCGCCATTCGACGACAACTGACCGCCAAATTGGACCCGCGAGCGGCCGCCAAGCGGAACATTAGCAAAACAGCCTCCGTGTCCGGCTCCAAGAAGTCCTCGTCAGCCTCATCCGTGGCGGTGAGCAAAGCGAACTCCTCCTACCTCAACTATGGCGTCGACTCGTACACTGTGAGTGTGGCGGCCAGCGCTAATTCTTCGGATGTCAGTTCCGGTTTCTTTTCCATCTCGGAGGTGGTGTCCGCTGCGGATGCCGCCGATGCGGCGGCcaaggcggcggcggccagcAAAACGGAACGCCGGACGCGCTGCTTCGAGTGCGAAATGTGCTCATCCATATTTCCCGATCGCGCCCAACTGCTGGAacacatgcatatacacaTCTAA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSETDMLEGGAADGEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANEAGGGTVLITDNGTVAYAESFDEDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGGRFSRRAELISHFKAHAEAQVAADAAAAAAAIKFEPQQRQIDDHFYEQWPLYQEQEQEEEQAQAQQLVQEQPAVTQASYAAAPTAARGRISRLKPKEESTQYIVLAEKQATSEVDELHQYMDCEELPTAGNASSGESGHAAEAAQPLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYEPASAGEDSASESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHKDAEGTDNAEAGDDAKDAAHCCHTCGKGFPSALELLAHAEIHARFPPFKCVLCGVSFYEEEAIKRHLKTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKMFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCTRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCAADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAGNKDGEDYASDIEYCDLDVENVDDLLDRVEPLPSKKEKRKRAAANPAKAVANGAAASSGSVKSANSSSERLWDEKFIGNGNVATDDAYKSFFQIDSLVVVNDTTLPPVSSVSGAASGARSRRSGKQAAAGSSDKLAAAGEESAKSGVSSRSSRRKTSKAAKSTGTAGAAAAAAGATVTASSSRPRMIHTEKSRVPLENPAKRSRGRSYVTRTSTSESSQLGLVKAGGGVASSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQLQQQQHHHHHHHHNHQQQQQRVQLMYDDTHLLIDAKTFEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTATGHTATPTSSSSSSSAEGALRAIRRQLTAKLDPRAAAKRNISKTASVSGSKKSSSASSVAVSKANSSYLNYGVDSYTVSVAASANSSDVSSGFFSISEVVSAADAADAAAKAAAASKTERRTRCFECEMCSSIFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00582391;
90% Identity: -
80% Identity: -