Basic Information

Insect: Drosophila arizonae
Gene Symbol: zfh1
Assembly: GCA_001654025.1
Location: NW:26754379-26759357[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.8e-05 0.0021 17.8 1.7 1 23 150 172 150 172 0.97

2 15 0.0007 0.039 13.9 1.2 3 23 180 200 178 200 0.94

3 15 7.6e-05 0.0043 16.9 0.1 1 23 365 387 365 387 0.98

4 15 0.013 0.7 9.9 0.7 1 23 393 415 393 415 0.98

5 15 1.3e-05 0.00072 19.3 2.1 1 23 446 469 446 469 0.96

6 15 0.00011 0.0063 16.4 0.5 1 23 493 515 493 515 0.95

7 15 0.015 0.84 9.7 1.3 1 23 521 544 521 544 0.97

8 15 0.022 1.2 9.1 0.5 3 19 553 569 552 570 0.95

9 15 0.00013 0.0074 16.1 5.6 1 23 579 601 579 601 0.97

10 15 0.034 1.9 8.5 1.2 2 23 607 628 606 628 0.96

11 15 7.8e-06 0.00043 20.0 1.0 1 23 637 659 637 659 0.98

12 15 0.00018 0.01 15.7 0.5 3 23 667 687 665 687 0.97

13 15 4.7e-05 0.0026 17.5 0.5 1 23 693 715 693 716 0.95

14 15 0.045 2.5 8.2 0.4 1 23 726 748 726 748 0.97

15 15 0.00047 0.027 14.4 0.5 1 23 1278 1300 1278 1300 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.8e-05	0.0021	17.8	1.7	1	23	150	172	150	172	0.97
2	15	0.0007	0.039	13.9	1.2	3	23	180	200	178	200	0.94
3	15	7.6e-05	0.0043	16.9	0.1	1	23	365	387	365	387	0.98
4	15	0.013	0.7	9.9	0.7	1	23	393	415	393	415	0.98
5	15	1.3e-05	0.00072	19.3	2.1	1	23	446	469	446	469	0.96
6	15	0.00011	0.0063	16.4	0.5	1	23	493	515	493	515	0.95
7	15	0.015	0.84	9.7	1.3	1	23	521	544	521	544	0.97
8	15	0.022	1.2	9.1	0.5	3	19	553	569	552	570	0.95
9	15	0.00013	0.0074	16.1	5.6	1	23	579	601	579	601	0.97
10	15	0.034	1.9	8.5	1.2	2	23	607	628	606	628	0.96
11	15	7.8e-06	0.00043	20.0	1.0	1	23	637	659	637	659	0.98
12	15	0.00018	0.01	15.7	0.5	3	23	667	687	665	687	0.97
13	15	4.7e-05	0.0026	17.5	0.5	1	23	693	715	693	716	0.95
14	15	0.045	2.5	8.2	0.4	1	23	726	748	726	748	0.97
15	15	0.00047	0.027	14.4	0.5	1	23	1278	1300	1278	1300	0.98

Sequence Information

Coding Sequence: ATGAACACTCAGGATTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCGGTGGACTCCGAGGCCGACCTACTGGAAAACGGCGCTGCCGACAGCGAGGTAGCGTCCGCCTACTTGGTCAATGGCAATGCAACCGATGAGGATCTCGACCATATGGCGGCTGAGAATCTCATATTCATGGCGCGTGATGGTCAACTGAGCGAGATAATTGCAGCCAACGAGAGCGGCGGCAGTACCGTCTTAATTACGGACAGTGGAACTGTTTCCTATGCCGCGGCATTTGATGAGGATGCCCAGGTGGTCACTGAGGAGATAATCACGGATGACTGGGTGCAGCACCAGGGCGCCGAGCGCGTGGAAATCGCTGCGGAACAAATCGCGGGCAACAACAGCTCGCAGGAGCTGCTGGACATGGAGCAGGACGAGTATACGGCACTGCGACCCTATCCCTGTGACTTCTGCAGCCGGCGTTTCCGCAAGAAGACCAGCCTGAACAATCACATGCTGGCGCATCAGAATGATCGTCCACATCTGTGTAAATTGTGCGGCGCTCGGTTCTCACGACGGGCCGAGCTTATCAGTCACTTCAAAGCGCACGCCGAGGCACAGGATGCTGCCGATGCGGCGGCAGCAATCAAATTCGAGCctccacagcaacaacaacgccaaatGGACGATCATTTCTATGAGCAGGAATGGTCACTGTACCAGGATCAGGAAGACGATCAAGTGCAACAAGATCTGCAGCAAATGGAACAAgaccagcaggagcagcatgaacagcaagagcaacagcagcagcagctcgtgcTGCCGCAGGCCAGCTATGCAGCAATTAGTGATGTGCCCGCCCCAACAGCCGCACGAGGTCGCATCAGCCGCCTCAAGCCCAAAGAGGAGAGCACTCAGTACATTGTGATTGGTGAGAAGCAGACAACGGACGACTTGCAGCCGTACATGGAGTGCGAGGAGCTGCAACCCGCGCTGACGAGTAGCACGTCAATTGAAGCAACGTCAGCGACGGCCAGCGCGTCCGTAGCTGAGGTGGCGGCGACTCCGCGCTTTCCGGTGATAGATGAAAGCAAACCGTTCGTGTGTCAGCAATGCGGCTTGGCATTTGCCCGCGAAAAGGCGCTGGTCTCGCACATTAAGAATCATCGAGTCGACTCTCCTTTCGAATGCAATCAATGCCAGGATATGTTCTGGGACAATTACAGTCTGCAGGAGCATCTGAAAACACACCAGTTCGAGGAGAGCAATTCGGAGTACGATCCGGCCTCTGCTGGCGACGACAGCGCCAGCGAGTCGGAGGCGGAACAGCTATACGGCGACTTCTACTGCAGCGAGTGCGGTATTTCATTTCACAGGCAGGACCTGCTGCGGCGCCAtgccaggcagcagcacaagcagctgCCCACGGCTGTGGAGGGCGGCGCTAGGGATGCTGATGCCGAGAGTGCCAAAGATGCGCAGCACTCTTGTCACACGTGCGGCAAATCGTTTCCCAGCGCCTTGGAGCTGCTCGCCCATGCCGAAGTACACGCGCGCTTCCCGCCCTTCAAATGCGTTCTGTGCGGCGTTAGCTTCTATGAGGAGCAGGCCATCAAGCGGCATTTACACACGCGCCATCCGCATGAGCTGAGACCCAACTCGTGCGTGCTGTGCGGCAAGGAGTGTCGCGATCGCAAGGCCCTGATGAAGCATGCCTGGGATCACTCGCGGGAGAAGTGCCACTCGTGCTCAAAGTGCGGCAAGAACTTTCACAACAAGGCGCGACTGAAGCGACACATGGCCTCGCATCGGGACAAGTCGGTGGTGTGCGAGGTGTGTCACGAGGAGTTCCCCGACGGGCGAACACTGTCCAATCATCGACATTCGCACAGCACCACCTCGCCGGGCAAACTGTTTCCCTGCCACGAGTGCGGCAAGACCTTCGGTTCGCGCAGCTCCCAGCAGATCCACGTGCGCATCCATACGGGAGAGCGACCATATGGCTGCCACTATTGCTGGAAAGCGTTCGCAGATGGCGGAACGCTGCGCAAGCACGAACGCATTCACACCGGCGAGAAGCCCTACGCGTGCTCCGTGTGTCCACGTGCCTTCAACCAGCGCGTCGTGCTGCGCGAGCACATACGCTCGCACCACTCGGGACTGGATGCTGTGCGAGGGACATACCACTGCACCGTCTGCTCGGCCGATCTGTCCTCGTCCAATGAGCTTATACAGCATCTCATCCAGCACAGCGACACGAACACCGCCAAGCAGCGACAGCCAATCACTGGTCCGCGAAAGTATAAGCGACGCAGGAAACTGCAGCCACATGAGATCGCGCACATGCGAGCGGAGCATAAGGATGGCGAGGATTATGCCAGCGACATGGAGTTCTGTGACCTGGATGTGGAGAATGTGGACGATCTGCTGGAAGGGGCAGACACGTTGCCAAGCAAAAAGGAGAAGCGCAAGCGTTCAGCTGCCAATCAGGCCAAGTCCGTGAGGAATGGGGGCGCAAGTAGCAATGCCTCTGCGTCGGTCAAGTCTGCCAATAGCAGCTGGGATGAGAAGTTCCTGCAGACAAACAGCAATGGCACCGCCGCCAACACTGATGAGAGCTTCTACCAGATTGATTCGCTCGTGGTGGTCAATGATACCACACTGCCGGCCGTCAGCCCATCCAGCAGTGCACAAGGTGCTTCCAAGTCGCGTCGAGGCGGAGGCAAGCAGGCCGAGAATGGCGATAAGTCCGGAGGAggaggcacagcagcagcaacagcatctacGACTAGCACAGAATCTAGCAAATCCCACGTCGCTaccagtcgcagcagcagccgaaagAAGGCCAGTAAGTCGGCCAAGAGTGCTGCCACAACATCATccgcaccagcaacagcagcagcatcgaccACGGCGAGCAGCTCGCGTCCACGAATGATACACACAGAAAAGTCGCGTGTGCCGCCAGAGAATGCATCGAAGAAGTCGCGTGGAGGCCGCACCTACATAACGCGCACCAACACCAGCGAGACCAGCAGCCAGTTGAATAGCCAGCTGGTCAAGTCGAGCGGCGTGTCCAGCTCTCGAATTGTGGATGATTACGAGATCATATCACCTGCCACCCAACCGCCCAATCAGATCAGTTCCAGTCCGCTGCACatcaagcaggagcaggagcagcagcagcagcgcatccAGTTCATGTTCGATGACACCCAATTGATCAACACTGCAATGTTGCGGGAGAAGCCCTACGACAAGTTCAATCCAAGCATTGTCAATGATCTCGAGGAGATATTGCGCAGTCCGCTCAAGCATGATCGGAATGCGCGGTTGCGCTTCACTAGCGAATCGTCTACAACGCTACAGTTCCTGCCCGAGTTGGAGCCAAATCTCATCAAGATTGAGCCCACATCGCCGGATCTGCGTGACATGGTGGAGAGCCAGCAGCGTGTCAATACCACAGCTGGACaggcggccacgcccacatcgtCATCCTCGTCGTCGGCGGCGCGCACATCGCGTCACCTGCGACAGCTGACGGCCAATGGCTCGAGCAGTCGCTCCGCTTCCAAGCGAAGCGCGGGCAAATCCTCAACGTCCTCCGGATCGAGCACCACAaagcccagcagcaacacatcCTCAACAGAGGCTGTCAGCAAGTCCTACCTCAGCTACGGTGTGGACTCCTACAATGTGGGCGTGACAACGAGTGCCAACTCGTCGGATGTCAGTTCCGGCTTCTTCTCCATCTCCGAGGTGGTGTCCGCTGCCCACGCAGCGGATGCGgccaaggcagcagcagccagcaaaacGGAGCGCCGGACCCGCTGCTTTGAGTGCGAGATGTGCTCATCCATATTTTCGGATCGGGCACAGCTGCTGgagcacatgcacatacacatctaA
Protein Sequence: MNTQDYGGIQWIQQHASAVDSEADLLENGAADSEVASAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGSTVLITDSGTVSYAAAFDEDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKTSLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAAAAIKFEPPQQQQRQMDDHFYEQEWSLYQDQEDDQVQQDLQQMEQDQQEQHEQQEQQQQQLVLPQASYAAISDVPAPTAARGRISRLKPKEESTQYIVIGEKQTTDDLQPYMECEELQPALTSSTSIEATSATASASVAEVAATPRFPVIDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQDMFWDNYSLQEHLKTHQFEESNSEYDPASAGDDSASESEAEQLYGDFYCSECGISFHRQDLLRRHARQQHKQLPTAVEGGARDADAESAKDAQHSCHTCGKSFPSALELLAHAEVHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELRPNSCVLCGKECRDRKALMKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCHYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCSADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGEDYASDMEFCDLDVENVDDLLEGADTLPSKKEKRKRSAANQAKSVRNGGASSNASASVKSANSSWDEKFLQTNSNGTAANTDESFYQIDSLVVVNDTTLPAVSPSSSAQGASKSRRGGGKQAENGDKSGGGGTAAATASTTSTESSKSHVATSRSSSRKKASKSAKSAATTSSAPATAAASTTASSSRPRMIHTEKSRVPPENASKKSRGGRTYITRTNTSETSSQLNSQLVKSSGVSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRIQFMFDDTQLINTAMLREKPYDKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTLQFLPELEPNLIKIEPTSPDLRDMVESQQRVNTTAGQAATPTSSSSSSAARTSRHLRQLTANGSSSRSASKRSAGKSSTSSGSSTTKPSSNTSSTEAVSKSYLSYGVDSYNVGVTTSANSSDVSSGFFSISEVVSAAHAADAAKAAAASKTERRTRCFECEMCSSIFSDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00582391;
90% Identity: iTF_00473204;
80% Identity: -