Dkan015824.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kanekoi
Gene Symbol
zfh1
Assembly
GCA_037075305.1
Location
JBAMCE010000665.1:4561684-4565876[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 4e-05 0.0026 18.2 1.1 1 23 150 172 150 172 0.97
2 15 0.00094 0.062 13.8 1.2 3 23 180 200 178 200 0.94
3 15 0.0001 0.0068 16.9 0.1 1 23 355 377 355 377 0.98
4 15 0.00035 0.023 15.2 0.9 1 23 383 405 383 405 0.98
5 15 3.9e-05 0.0026 18.2 2.2 1 23 436 459 436 459 0.95
6 15 0.00064 0.042 14.4 1.9 1 23 495 517 495 517 0.95
7 15 0.02 1.3 9.7 1.3 1 23 523 546 523 546 0.97
8 15 0.03 2 9.1 0.4 3 19 555 571 554 572 0.95
9 15 0.00018 0.012 16.1 5.6 1 23 581 603 581 603 0.97
10 15 0.046 3.1 8.5 1.2 2 23 609 630 608 630 0.96
11 15 1e-05 0.00069 20.0 1.0 1 23 639 661 639 661 0.98
12 15 0.0012 0.078 13.5 0.1 3 23 669 689 667 689 0.97
13 15 6.3e-05 0.0042 17.5 0.5 1 23 695 717 695 718 0.95
14 15 0.06 4 8.2 0.4 1 23 728 750 728 750 0.97
15 15 0.0018 0.12 13.0 0.3 1 23 1293 1315 1293 1315 0.98

Sequence Information

Coding Sequence
ATGAACAACCAGGACTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCGGTTGATTCCGAAACAGATATGCTGGAAAACGGCGCTGCTGACAGCGAGGTGACTGCCGCCTATTTGGTAAATGGCAATGCAACAGACGAGGATCTTGACCATATGGCGGCCGAGAATCTTATCTTCATGGCGCGTGATGGTCAGCTAAGCGAAATCATAGCCGCCAACGAAGCCGGCGGCGGAACTGTATTAATCACGGACAGCGGCACCGTTGCCTATGCCGAGTcttttgatgatgatgcacAGGTGGTCACCGAGGAGATCATTACCGATGATTGGGTGCAGCATCAGGGTGCCGAGCGaGTGGAAATCGCCGCAGAGCAAATAGCGGGCAACAACAGCTCGCAGGAGCTGCTGGACATGGAGCAGGATGAATATACCGCGCTGCGCCCGTATCCTTGCGACTTTTGTAGCCGACGCTTTCGCAAAAAGGGCAGCCTCAATACTCACATGCTGGCGCACCAAAACGATCGTCCACATCTGTGTAAATTGTGCGGCGCACGTTTTTCAAGGCGCGCTGAGCTCATCAGTCACTTCAAGGCGCATGCCGAGGCACAGGTTGCGGCAGATGAGGCggctgcaattaaatttgagccgcagcaacagcaacgccaAGCGGATGATCATTATTACGAACAGGATTGGCCCTTGTACCAGGAACAGGAAGAGGACCAGGTTCAAGACCAGATGCAGCAaatggagcaggagcagctggtAGAGCCGCAGGCCAGCTATGCAGCGGTTAGCGCTGTGTCCGCTCCAATAGCCACGCGTGGCCGCATCAGCCGCCTCAAGCCCAAAGAAGAGAGCACGCAGTACATTGTGATTGCCGAGAAGCAGACATCTGACGATTTGCGCCAGTACATGGATTGCGaagagctgccgctgcagccgccgcTCAATGACGGCACGTCAATCGATGCATCGCATTCGACAGAGTGCCCGGACGGCCCAGTCGCCGATGGGGCAGAATCGTTACGCTTTCCGGTGCTGGACGAGAGCAAGCCCTTTGTGTGCCAGCAGTGTGGACTCGCATTTGCTCGCGAAAAAGCGCTCGTCTCGCATATCAAGAATCATCGCGTGGACTCGCCCTTCGAATGCAATCAGTGTCAGGAGATGTTCTGGGATAATTACAGCCTGCAGGAACATCAGAAGACACATCAGTTTGAGGAGAGCAACTCGGAATATGATCCGGCTTCGGCGTGCGAAGATAGCGCCAGCGAATCGGAGCCGGATCAGCTTTACGGTGATTTCTACTGCAGCGAGTGTGGCATTTCCTTTCACAGGCAGGACCTGCTGCGTCGTCATGCCAAGCAACAGCACAAGCTGACACCAGACATGGACGGCGGCGaaggcggtggcggcggcggcggcgaagGTGATGGCGACGTCGGCGATGCTGATGCCGGAAATGTCAAAGACGCCGCGCACTGTTGTCACACTTGCGGCAAATCGTTTCCCAGCGCACTGGAGCTGCTCGCCCATGCCGAAGTCCATGCACGCTTCCCGCCATTCAAATGCGTCCTGTGCGGTGTTAGCTTTTACGAGGAGCAGGCTATCAAGCGGCATTTGCACACGCGCCATCCGCACGAACTGAAGCCCAACTCGTGCGTGCTGTGCGGCAAAGAGTGTCGCGATCGCAAGGCACTGATCAAGCACGCCTGGGATCACTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCGCGTCTAAAGCGACACATGGCCTCGCATCGCGACAAGTCGGTGGTTTGCGAGGTGTGCCACGAGGAGTTCCCCGATGGACGCACGCTTTCCAATCATCGCCATTCACATAGCACAACATCGCCAGGCAAGCTGTTTCCCTGCCACGAGTGCGGCAAGACCTTTGGGTCGCGCAGCTCACAGCAGATACATGTCCGCATCCATACCGGCGAACGGCCATATGGCTGTCGCTACTGCTGGAAGGCGTTTGCCGATGGCGGTACGTTGCGCAAGCACGAACGCATTCACACGGGCGAGAAGCCCTACGCCTGTTCCGTGTGTCCGCGTGCCTTCAATCAGCGCGTTGTGCTGCGCGAGCACATACGCTCCCATCACTCGGGTCTGGATGCAGTACGTGGCACCTATCATTGCACCGTCTGCTCGGCCGATTTGTCCTCATCCAACGAGCTTATACAGCATCTCATCCAGCACAGCGACACAAACACCGCCAAACAGCGACAGCCAATTACTGGTCCGCGCAAGTATAAGCGACGCAGGAAACTGCAGCCACACGAGATTGCCCACATGCGTGCGGGGAACAAGGATGGCGAGGAGTATGCCAGCGATATGGAACTGTGTGATTTTGATGTTGAGAACGTGGATGATCTCCTGGACACGACGGAGCCATTGCCAACCAAAAAGGAGAAACGCAAGAAGGCAGCTGCAAATCAAGCTAAGGCCGTGACGAATGGCGCCACACACAATAGCTCCAGTTCTGCCAAATCCGCCAATAGCAGCTCGGAACGTCTGTGGGATGAGAAATTCCTGCCGGCAAACAGCAATGGTAATGTTGGCAACGCAGATGATGCCTACAAAAGCTTCTTTCAAATTGATTCGCTCGTGGTGGTAAATGGTACCACTCTGCCGCCTGTAAGCTCATCCAGCAGCACACCAAGCGCCTCCAAGTCGCGACGCGGCGGCAAGCAGCCACCGACGCAAACACAGGCCGAGAGCAGTGACAAGTCAGGAGGTGGAGCGAGAGccacagcatcagcaacaccaacaacaacgacaacaactacagcagcagcagcggctgcggctgcagctggtgAGGAGTCTGGCAAATCCAGCGTTgccaacagccgcagcagcagaaagaagTCTAGCAAGGCGGCCAAGAATAcaggcacagcagctgccgcaacaAGCAGTTCACGTCCCCGCATGATACACACAGAAAAGGCACGTGTGCCGCCGGAGAATGCCAGCAAAAAGTCGCGTGGTCGCAGCTACATAACGCGCACCAGCACCAGCGAGAGCAGCCAGCTGGGCCTGGTCAAGTCGAGCGGCGTCGCCAGTTCGCGGATTGTCGATGACTACGAAATTATATCACCTGCCACACAGCCGCCGAATCAGATCAGCTCCAGTCCGCTGCACAtcaagcaggagcaggagcagcaacagcagcgcgtCCAGCTCATGTACGATGATACCCATTTGCTGATGCATGCGGCCATGTTGCGCGATAAGCCCTATGACAAGTTCAATCCGAGCATTGTCAATGATCTGGAGGAGATATTACGCAGTCCGCTCAAGCATGATCGGAATGCTCGCCTGCGTTTCACTAGCGAATCGTCGACAACGCCACAGTTTCTGCCCGAGGAGGAGCAGAACCTCATTAAAATAGAGCCCACATCTCCGGATCTGCGCGAAATGGTGGAGAGCCAGCAACGTGTAACTGCCACAGGAcacacagccacgcccacatcatcatcatcatcctcatcggCGGCGCGTACATCGCGCCATCTGCGACAGATCACTGCCAACTCGGCCACCCGCTCGGCAGCCAAGCGACACATGGACAAAAGCTCATCCGAATTCAGCGCCAAGAAATCGACAACATCCACGCCCGTTTCAGTCAGTAAGCCAGCCGCCAATTCTTACCTCAGCTATGGCGTTGACTCGTACAATGTGAATGTGGTGGCCAGTGCCAACTCCTCGGATGTCAGTTCCGGTTTCTTTTCCATCTCCGAGGTGGTATCCGCTGCACATGCCGCCGATGCCGCGGCCAAGGCAGCAGCGGCCAGCAAAACGGAGCGTCGGACACGCTGCTTTGAGTGTGAAATGTGCTCTTCCATATTTCCCGATCGCGCCCAGCTGCTGgagcacatgcatatacacatctGA
Protein Sequence
MNNQDYGGIQWIQQHASAVDSETDMLENGAADSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANEAGGGTVLITDSGTVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKGSLNTHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEAAAIKFEPQQQQRQADDHYYEQDWPLYQEQEEDQVQDQMQQMEQEQLVEPQASYAAVSAVSAPIATRGRISRLKPKEESTQYIVIAEKQTSDDLRQYMDCEELPLQPPLNDGTSIDASHSTECPDGPVADGAESLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASACEDSASESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHKLTPDMDGGEGGGGGGGEGDGDVGDADAGNVKDAAHCCHTCGKSFPSALELLAHAEVHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCSADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAGNKDGEEYASDMELCDFDVENVDDLLDTTEPLPTKKEKRKKAAANQAKAVTNGATHNSSSSAKSANSSSERLWDEKFLPANSNGNVGNADDAYKSFFQIDSLVVVNGTTLPPVSSSSSTPSASKSRRGGKQPPTQTQAESSDKSGGGARATASATPTTTTTTTAAAAAAAAAGEESGKSSVANSRSSRKKSSKAAKNTGTAAAATSSSRPRMIHTEKARVPPENASKKSRGRSYITRTSTSESSQLGLVKSSGVASSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRVQLMYDDTHLLMHAAMLRDKPYDKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTATGHTATPTSSSSSSSAARTSRHLRQITANSATRSAAKRHMDKSSSEFSAKKSTTSTPVSVSKPAANSYLSYGVDSYNVNVVASANSSDVSSGFFSISEVVSAAHAADAAAKAAAASKTERRTRCFECEMCSSIFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00582391;
90% Identity
iTF_00563313;
80% Identity
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