Basic Information

Insect: Drosophila gaucha
Gene Symbol: zfh1
Assembly: GCA_035045545.1
Location: JAWNOY010000176.1:3187-7275[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.002 18.6 1.0 1 23 149 171 149 171 0.97

2 15 0.00088 0.063 13.9 1.2 3 23 179 199 177 199 0.94

3 15 9.6e-05 0.0069 16.9 0.1 1 23 354 376 354 376 0.98

4 15 0.00033 0.024 15.2 0.9 1 23 382 404 382 404 0.98

5 15 3.6e-05 0.0026 18.2 2.2 1 23 435 458 435 458 0.95

6 15 0.00054 0.039 14.5 0.1 1 23 482 504 482 504 0.96

7 15 0.019 1.3 9.7 1.3 1 23 510 533 510 533 0.97

8 15 0.028 2 9.1 0.4 3 19 542 558 541 559 0.95

9 15 0.00017 0.012 16.2 5.6 1 23 568 590 568 590 0.97

10 15 0.043 3.1 8.6 1.2 2 23 596 617 595 617 0.96

11 15 9.8e-06 0.0007 20.0 1.0 1 23 626 648 626 648 0.98

12 15 0.0011 0.079 13.6 0.1 3 23 656 676 654 676 0.97

13 15 5.9e-05 0.0042 17.6 0.5 1 23 682 704 682 705 0.95

14 15 0.29 21 5.9 0.3 1 23 715 737 715 737 0.96

15 15 0.0017 0.12 13.0 0.3 1 23 1260 1282 1260 1282 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.002	18.6	1.0	1	23	149	171	149	171	0.97
2	15	0.00088	0.063	13.9	1.2	3	23	179	199	177	199	0.94
3	15	9.6e-05	0.0069	16.9	0.1	1	23	354	376	354	376	0.98
4	15	0.00033	0.024	15.2	0.9	1	23	382	404	382	404	0.98
5	15	3.6e-05	0.0026	18.2	2.2	1	23	435	458	435	458	0.95
6	15	0.00054	0.039	14.5	0.1	1	23	482	504	482	504	0.96
7	15	0.019	1.3	9.7	1.3	1	23	510	533	510	533	0.97
8	15	0.028	2	9.1	0.4	3	19	542	558	541	559	0.95
9	15	0.00017	0.012	16.2	5.6	1	23	568	590	568	590	0.97
10	15	0.043	3.1	8.6	1.2	2	23	596	617	595	617	0.96
11	15	9.8e-06	0.0007	20.0	1.0	1	23	626	648	626	648	0.98
12	15	0.0011	0.079	13.6	0.1	3	23	656	676	654	676	0.97
13	15	5.9e-05	0.0042	17.6	0.5	1	23	682	704	682	705	0.95
14	15	0.29	21	5.9	0.3	1	23	715	737	715	737	0.96
15	15	0.0017	0.12	13.0	0.3	1	23	1260	1282	1260	1282	0.98

Sequence Information

Coding Sequence: ATGAACAATCAGGACTATGGAGGCATCCAATGGATACAGCAGCACGCATCCGCGGTTGACTCCGAAACCGATTTACTGGAAAACGGCGCTGATGACAGCGAGGTAACGGCTGCCTATTTGGTCAATGGCAATGCAACCGACGAGGATCTTGACCATATGGCGGCCGAGAATCTCATCTTCATGGCACGCGATGGCCAGCTAAGCGAGATCATTGCCGCCAACGAAGGTGGCGGCACTGTATTAATTACTGATAGCGGCTCCGTTGCCTATGCTGAGTCATTTGATGAAGACGCACAGGTGGTCACCGAGGAAATCATCACCGATGACTGGGTGCAGCATCAGGGTGCCGAGCGcGTGGAAATCGCCGCGGAGCAAATAGCGGGCAACAACAGTTCGCAGGAGCTGCTGGACATGGAGCAGGATGAATATACGGCATTGCGACCCTATCCGTGTGATTTTTGCAGCCGGCGCTTTCGCAAAAAGGCCAGCCTTAACAATCATATGCTGGCGCATCAAAATGATCGTCCGCATCTGTGTAAATTGTGCGGCGCTCGATTCTCACGGCGAGCCGAGCTCATCAGTCACTTCAAGGCACATGCCGAGGCACAGGTTGCGGCAGATGCGGCGGCAGCAATTAAATttgagccgcagcagcagcaacgccaaATGGATGACCATTTCTACGAGCAGGAATGGCCTTTGTATCAGGAACAGGAAGACGatcaagtgcagcagcagctgcagcaaatggagcaagagcaggagcaggaacAGCTTGTAATGCCGCAGCCCAGCTATGCAGCGATCACTGCTGTGTCAGCGCCAACAGCCACACGCGGTCGCATTAGCCGCCTCAAGCCCAAGGAGGAGAGCACGCAGTACATTGTGATTGCCGAGAAGCAGACAACGGATGATTTGCAGGAGTACATGGACTGCGAAGAGCTGCCGCAAACGCTGACAAGCAGCACGTCAATTGATGCGACGGATGACACGGTCAGCGTTCCCGTTGCTGACGCGGCACAGGCTCAACGCTTTCCGGTGATAGACGATAGCAAACCCTTTGTGTGCCAGCAATGCGGTTTAGCTTTTGCGCGTGAAAAGGCGCTCGTCTCGCACATTAAGAATCACCGCGTGGACTCGCCCTTCGAATGCAATCAGTGCCAAGAGATGTTCTGGGACAATTACAGCCTGCAGGAGCATCAGAAGACACATCAGTTCGAGGAGAGCAATTCGGAGTATGATCCGGCCTCGGCCGGCGATGATAGCGTCACCGAATCAGAACCGGAGCAGCTATACGGTGACTTCTACTGCAGCGAGTGCGGCATTTCTTTTCACAGGCAGGACCTGCTGCGACGCCatgccaagcagcagcacaagcagCAGTCCACGGATGTGGAGGGCGCCGCCGGCGATGCTGATGCCGAAAATGCCAAAGATGCGCAGCACTATTGCCTTACATGCGGCAAATCGTTTCCTAGCGCCCTGGAGCTACTTGCCCATGTCGAGGTGCATGCTCGCTTCCCGCCATTCAAATGCGTGTTGTGCGGTGTTAGCTTCTACGAGGAGCAGGCTATCAAGCGGCATTTACACACACGTCATCCGAACGAGCTGAAGCCCAATTCGTGTGTGCTGTGCGGCAAGGAGTGTCGCGATCGCAAGGCCCTGATCAAGCATGCTTGGGATCATTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGAAAAAACTTTCACAACAAGGCACGACTGAAGCGGCATATGGCCTCACATCGCGATAAGTCAGTGGTGTGCGAGGTATGCCACGAGGAGTTCCCCGACGGACGCACTCTATCCAATCATCGACATTCACACAGCACCACATCGCCGGGCAAACTGTTTCCTTGCCACGAATGCGGCAAGACCTTTGGATCGCGCAGTTCACAGCAGATTCATGTGCGTATCCATACAGGTGAACGGCCTTACGGCTGTCGCTATTGCTGGAAGGCGTTTGCGGATGGAGGGACACTGCGCAAGCATGAACGCATCCACACGGGCGAGAAGCCCTATGCCTGTTCCGTGTGCCCACGTGCCTTCAATCAGCGCGTTGTGCTCCGCGAGCATATACGTTCGCATCACTCGGGCATGGATACGGTCCGGGGCACCTATCACTGCACCGTTTGCCTGGCCGATTTGTCCTCATCCAATGAGCTCATACAGCATCTCATCCAGCACAGTGATACGAACACCGCCAAACAGCGACAACCGATTACTGGACCACGCAAGTACAAGCGACGCAGGAAACTTCAGCCACACGAGATTGCCCATATGCGTGCGGAGCATAAGGATGGCGAGGAGTATACCAGCGATATGGAATTCTGTGACTTGGATGTAGAGAATGTGGATGATCTTCTGGACGGTGCGGACACATTGCCAATTAAAAAGGAGAAACGCAAGCGTCCAGCTGCAAATCAAGCTAAATCCGTAACAAATGGCGGTGCACAAAACGACGTCTCTGCTTCGGTGAAATCCGCCGATAGCAGTTGGGATGAAAAGTTCCTGCAGACAAATGGCAATGGTAACGTTGCCAACGTTGATGATGCCTATAAGAGCATCTTCCAAATTGATTCACTGGTGGTGGTCAATGATACCACACTGCCAGCCGTTAGCTCATCTAGCAATGCATCAGGCGCAGCCAAATCGCGACGGGGCGGTGGTAAGCAGGCCGAGAACGGTGTCAAGTcgggaggaggagcagcagcagcaggaacagctGCAGCTAACGAAGAGACTGGCAAATCCAAAGTCgccagcagtcgcagcagtaGCCGGAAAAAGTCGAGCAAGGCGGCCAAGAATGCAGCCACAGCTGCAGCGGCCACAGCAAGTAGCTCGCGTCCACGCATGATACACACGGAAAAGTCACGTGTGCCGCCAGAGAATGCATCCAAGAAATCACGTAGTCGGAGCTACATTACACGCACCAGCACCAgcgagagcagcagccagctgGGGCAGCTGGTTAAGTCGAGCGGTGTGTCCAGTTCCAGGATTGTCGACGACTACGAGATTATATCACCTGCCACCCAGCCGCCCAATCAGATCAGCTCCAGTCCATTGCACATcaagcaggagcaggagcagcagcagcagcgcgtcCAGCTTATGTACGATGACACCCATCTGCTGATCCATGGTGCAATGTTGCGGGAGAAGACCTACGATAAGTTCAATCCAAGCATTGTCAATGATCTCGAGGAGATTTTGCGTAGTCCACTCAAGCATGATCGTAATGCTCGATTGCGTTTCACCAGCGAATCGTCGACAACGCCACAGTTTCTGCCCGAGGAGGAGCAGAATCTCATTAAGATTGAGCCCACGTCGCCGGATCTGCGCGATATGGTGGAGAGCCAGCAGCGCGTTACTGCCACAACTGGACAAACGGCAACTcccacatcatcatcatcgtcgtcgtcggcggCGCGCACATCGCGCCATCTGCGACAGCTCAGTGCCAACTCGGGCAGCCGAGCAGCGTCCAAGCGCAGCATTGGCAAATCCTCAACAGCCGCCTCCAGCGCCAAGAAACCATGCAGCAGCACATCCTCAACAGAAGCTGTCAGCAAGTCGTATCTCAGCTATGGCGTGGACTCCTACAATGTGAGTGTGGCTGCCAGTGCCAACTCTTCGGATGTCAGCTCCGGTTTCTTCTCCATCTCCGAGGTGGTATCCGCAGCACATGCTGCCGACGCGGCGGCCAAGGCAGCAGCTGCGAGTAAAACGGTACGTCGGACTCGCTGCTTCGAATGCGAAATGTGCTCATCCATATTTCCCGATCGCGCCCAGCTGCTGgagcatatgcatatacacatctaa
Protein Sequence: MNNQDYGGIQWIQQHASAVDSETDLLENGADDSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANEGGGTVLITDSGSVAYAESFDEDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADAAAAIKFEPQQQQRQMDDHFYEQEWPLYQEQEDDQVQQQLQQMEQEQEQEQLVMPQPSYAAITAVSAPTATRGRISRLKPKEESTQYIVIAEKQTTDDLQEYMDCEELPQTLTSSTSIDATDDTVSVPVADAAQAQRFPVIDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGDDSVTESEPEQLYGDFYCSECGISFHRQDLLRRHAKQQHKQQSTDVEGAAGDADAENAKDAQHYCLTCGKSFPSALELLAHVEVHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPNELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGMDTVRGTYHCTVCLADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGEEYTSDMEFCDLDVENVDDLLDGADTLPIKKEKRKRPAANQAKSVTNGGAQNDVSASVKSADSSWDEKFLQTNGNGNVANVDDAYKSIFQIDSLVVVNDTTLPAVSSSSNASGAAKSRRGGGKQAENGVKSGGGAAAAGTAAANEETGKSKVASSRSSSRKKSSKAAKNAATAAAATASSSRPRMIHTEKSRVPPENASKKSRSRSYITRTSTSESSSQLGQLVKSSGVSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRVQLMYDDTHLLIHGAMLREKTYDKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLRDMVESQQRVTATTGQTATPTSSSSSSSAARTSRHLRQLSANSGSRAASKRSIGKSSTAASSAKKPCSSTSSTEAVSKSYLSYGVDSYNVSVAASANSSDVSSGFFSISEVVSAAHAADAAAKAAAASKTVRRTRCFECEMCSSIFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00582391;
90% Identity: iTF_00559631;
80% Identity: -