Basic Information

Insect: Drosophila robusta
Gene Symbol: zfh1
Assembly: GCA_004143805.1
Location: SCDV01001850.1:8183-13560[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.3e-05 0.0029 18.5 1.0 1 23 150 172 150 172 0.97

2 15 0.003 0.37 11.9 1.2 3 23 180 200 178 200 0.94

3 15 7.8e-05 0.0099 16.9 0.1 1 23 367 389 367 389 0.98

4 15 0.00027 0.034 15.2 0.9 1 23 395 417 395 417 0.98

5 15 2.5e-05 0.0031 18.4 1.8 1 23 448 471 448 471 0.95

6 15 0.00083 0.1 13.7 1.3 1 23 500 522 500 522 0.95

7 15 0.0016 0.2 12.8 0.4 1 23 528 551 528 551 0.98

8 15 0.023 2.9 9.1 0.4 3 19 560 576 559 577 0.95

9 15 0.00014 0.017 16.1 5.6 1 23 586 608 586 608 0.97

10 15 0.035 4.5 8.5 1.2 2 23 614 635 613 635 0.96

11 15 8e-06 0.001 20.0 1.0 1 23 644 666 644 666 0.98

12 15 0.00091 0.11 13.5 0.1 3 23 674 694 672 694 0.97

13 15 0.00013 0.016 16.2 0.9 1 23 700 722 700 723 0.95

14 15 0.19 24 6.2 0.2 1 23 733 755 733 755 0.96

15 15 0.00015 0.018 16.0 0.3 1 23 1291 1313 1291 1313 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.3e-05	0.0029	18.5	1.0	1	23	150	172	150	172	0.97
2	15	0.003	0.37	11.9	1.2	3	23	180	200	178	200	0.94
3	15	7.8e-05	0.0099	16.9	0.1	1	23	367	389	367	389	0.98
4	15	0.00027	0.034	15.2	0.9	1	23	395	417	395	417	0.98
5	15	2.5e-05	0.0031	18.4	1.8	1	23	448	471	448	471	0.95
6	15	0.00083	0.1	13.7	1.3	1	23	500	522	500	522	0.95
7	15	0.0016	0.2	12.8	0.4	1	23	528	551	528	551	0.98
8	15	0.023	2.9	9.1	0.4	3	19	560	576	559	577	0.95
9	15	0.00014	0.017	16.1	5.6	1	23	586	608	586	608	0.97
10	15	0.035	4.5	8.5	1.2	2	23	614	635	613	635	0.96
11	15	8e-06	0.001	20.0	1.0	1	23	644	666	644	666	0.98
12	15	0.00091	0.11	13.5	0.1	3	23	674	694	672	694	0.97
13	15	0.00013	0.016	16.2	0.9	1	23	700	722	700	723	0.95
14	15	0.19	24	6.2	0.2	1	23	733	755	733	755	0.96
15	15	0.00015	0.018	16.0	0.3	1	23	1291	1313	1291	1313	0.98

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACAGCAGCACGCCTCGGCGGTTGACTCCGAGACGGACATATTGGAAAGCGGCGCCGCCGACGGCGAGGTGACCGCCGCCTATTTGGTGAACGGGAATGCCACCGACGAGGATCTCGACCATATGGCGGCCGAGAATCTCATCTTCATGGCGCGTGACGGCCAGCTGAGCGAGATTATTGCCGCCAACGAAACGGGCGGCGGCACCGTGTTAATCACTGACAACGGCACAGTTGCCTACGCGGAATCCTTTGACGACGATGCACAGGTGGTTACCGAGGAGATCATCACCGATGACTGGGTGCAGCACCAGGGTGCCGAGCGCGTGGAAATCGCGGCCGAGCAAATTGCGGGGAACAACAGTTCGCAAGAGCTGCTGGACATGGAGCAGGATGAGTACACGGCGCTGCGCCCATATCCATGTGACTTCTGCAGCCGGCGCTTCCGCAAGAAGGCCAGCCTCAACAATCACATGCTAGCGCATCAGAACGACCGTCCGCATCTGTGCAAGCTGTGCGGCGGACGTTTCTCGCGGCGCGCCGAGCTGATCAGTCACTTCAAGGCGCACGCCGAGGCACAGGTTGCGGCGGATGCGGAGGCcgcggcggccgcagcagcggcggcgtctgcaattaaattcgagccgcagcagcagcaacgaccaATCGATGATCATTTCTACGAACAATGGCCTCTTTATCAGGACCAGGAGCAagaccaggaccaggaccaggagCAGGAAGAAGACCAAGTGCAGGAACAGGCGCAGGCACAGCAACTGGTACAGGAGCACCAAACTGTGCCACAGGCCACCTATGCGGCGGTCAGCGATATGGCAGCACCAACAGCCACACGCGGTCGCATAAGTCGCCTCAAGCCCAAGGAGGAGAGCACTCAGTACATTGTGATCGCCGAGAAGCAGGCGACATCTGTGGTCGATGATCTACGTCAGTACATGGATTGCgaggagctgccgctggcggACAACACCTCGGTCGGGGAAAGCGGCCAAGCCGCAGATGGAGCGCAGTCTCTGCGCTTTCCGGTACTGGACGAGAGCAAGCCGTTTGTGTGCCAGCAGTGCGGTTTGGCGTTTGCGCGCGAGAAGGCGCTCGTCTCGCATATCAAGAATCATCGCGTGGACTCGCCGTTCGAGTGCAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGCCTGCAGGAGCATCAGAAGACACATCAGTTCGAAGAGAGCAACTCGGAGTACGATCCGGCCTCGGCGGGCGAGGATAGCGCCAGCGAATCGGAACCGGATCAGCTGTACGGCGACTTCTACTGCAGCGAGTGCGGCATTTCATTTCACAGGCAAGATCTGCTCCGGCGCCATGCCAAGGAGCAGCACAAACTGGGCGCCGGCCACGCTGCGACGGATGCggagggcggcggcggtgaTGCAGATGGCGGCGAGAATGCCAAAGATGCGCCACACTGTTGTCATACGTGCGGCAAAGCCTTTCCCAGCGCACTGGAGCTGCTCGCCCATGCCGAGATTCATGCCCGTTTCCCGCCATTCAAATGCGTCCTGTGCGGTGTCAGCTTTTACGAGGAGGAGGCCATCAAGCGGCATTTGAAGACGCGTCATCCGCACGAGCTGAAACCCAACTCGTGCGTGCTGTGCGGTAAGGAGTGCCGGGATCGCAAGGCGCTGATCAAGCACGCCTGGGACCATTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCACAACAAGGCGCGCCTGAAGCGGCACATGGCCTCCCATCGCGACAAGTCGGTGGTGTGCGAGGTCTGCCACGAGGAGTTCCCCGATGGCCGCACCCTCTCAAACCACCGCCACTCGCACAGCACCACATCGCCGGGCAAACTGTTCCCCTGCCACGAGTGCGGTAAGACCTTTGGATCGCGCAGCTCTCAGCAGATACACGTGCGCATCCACACGGGCGAACGACCCTATGGCTGTCGTTACTGCTGGAAGGCGTTCGCCGATGGCGGCACACTGCGCAAACATGAACGCATCCACACCGGCGAGAAGCCCTACGCCTGCTCCGTGTGCACGCGTGCCTTCAATCAGCGCGTGGTGCTCCGCGAGCACATACGCTCCCATCACTCGGGCCTGGACGCGGTGCGCGGCACCTACCACTGCACCGTCTGCGCGGCCGACTTGTCCTCATCCAATGAGCTCATCCAGCATCTCATCCAGCACAGCGATACGAACACGGCCAAACAGCGACAGCCCATTACCGGGCCGCGCAAGTACAAGCGCCGTAGGAAACTGCAGCCACACGAGATTGCGCACATGCGCGCGGGCAACAAGGATGGTGAGGATTATGTCAGCGACATTGAATATTGCGATTTGGATGTGGAAAATGTCGACGATCTCCTCGACCGCGCCGAGCCATTGCCCATCAAAAAGGAGAAGCGCAAGCGGACAGCTGCAAATCAAGCCAAAGCCGTGGCCAATGGCGCCGCTGCGTCCACACAGAACACCTCCAGCTCGGCGAAGTCAACCAACAGCAGCTCGGATCGTCTGTGGGATGACAAGTTCATGCAGAtgaacggcaacggcaacgtgGCCAGTGACGATGGATACAAGAGCATCTTTCAGATTGACTCACTGGTGGTGGTGAACGATACCACCCTGCCGGCCGTCAGCTCCTCCAGCACTGCGGCAAGTGGCGCCAAGTCGCGGCGCGGCGGCAAGCAAGCGCAGGCCCAGACGCAGCCAGCGGGCAGCAGCGACAAGTTgacggcagcagctggcgaGGAGTCGGCAAAGTCTGGCGCCTCCAGCActcgcagcagcagaaagAGAACAAGCAAGGCGGCCAAGAATACCGCCGAAgcggcaggcgctgcagctgcagccacagTCAGCAATTCGCGTCCCCGCATGATACACACGGAAAAGTCACGTGTGCCGCCGGAGAATCCGCCGAAGAGGTCGCGGGGCCGCAGCTACGTGACGCGCACCAGCACCAGCGAGAGCAGCCAGCTGGGGCTGGGCAACGCGGGCGGTGTTGCCAGCTCGCGTATTGTCGATGACTACGAGATTATATCACCTGCCACACAGCCGCCCAATCAGATCAGCTCCAGTCCGCTGCACAtcaagcaggagcaggagcaactgcagcagcatcagcacaaccagcagcagcagcagcagcgcgtgCAGCTCATGTACGACGACACGCATCTGCTGATCGATGCGACACTGCTGCGCGAGAAGACCTTCGAGAAGTTCAATCCGAGTATTGTCAACGATCTCGAGGAGATTCTGCGCAGTCCGCTCAAGCACGATCGCAATGCCCGGCTGCGTTTCACCAGCGAATCATCGAACACGCCCCAGTTTCTGCCCGAGGAGGAGCAgaatctaattaaaattgagcCTACGTCGCCGGATCTGCGGGAAATGGTGGAGAGCCAGCAGCGTGTAACTGCCACGGGACACAGCGGAcacacggccacgcccacatcctcgtcgtcgtcggcccGCACTTCGCGCCATCTGCGACAGCTCAGCGCCAACTTGGGCTCGCGTGCGGCAGCCAAGCGGAACATTGGCAAAGCAGCCTCCGCGTCCGGCTCCAAGAAATCATCCTCAGCCACATCCGTGGCCGTCAGCAAAGCGAACTCCTCCTACCTCAGCTATGGCGTGGACTCGTACACTGTGAGTGTGGCGGCCAGCGCCAACTCTTCCGATGTCAGTTCCGGTTTCTTCTCCATCTCGGAGGTGGTGTCCGCTGCGGATGCCGCCGATGCGGCGGccaaggcggcggcggccagcaaAACGGAGCGACGAACACGGTGCTTTGAGTGTGAAATGTGCTCGTACATATTTCCCGATCgcgcccagctgctggagcatatgcatatacacatctga
Protein Sequence: MNNQDYGGIQWIQQHASAVDSETDILESGAADGEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANETGGGTVLITDNGTVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGGRFSRRAELISHFKAHAEAQVAADAEAAAAAAAAASAIKFEPQQQQRPIDDHFYEQWPLYQDQEQDQDQDQEQEEDQVQEQAQAQQLVQEHQTVPQATYAAVSDMAAPTATRGRISRLKPKEESTQYIVIAEKQATSVVDDLRQYMDCEELPLADNTSVGESGQAADGAQSLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEDSASESEPDQLYGDFYCSECGISFHRQDLLRRHAKEQHKLGAGHAATDAEGGGGDADGGENAKDAPHCCHTCGKAFPSALELLAHAEIHARFPPFKCVLCGVSFYEEEAIKRHLKTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCTRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCAADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAGNKDGEDYVSDIEYCDLDVENVDDLLDRAEPLPIKKEKRKRTAANQAKAVANGAAASTQNTSSSAKSTNSSSDRLWDDKFMQMNGNGNVASDDGYKSIFQIDSLVVVNDTTLPAVSSSSTAASGAKSRRGGKQAQAQTQPAGSSDKLTAAAGEESAKSGASSTRSSRKRTSKAAKNTAEAAGAAAAATVSNSRPRMIHTEKSRVPPENPPKRSRGRSYVTRTSTSESSQLGLGNAGGVASSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQLQQHQHNQQQQQQRVQLMYDDTHLLIDATLLREKTFEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSNTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTATGHSGHTATPTSSSSSARTSRHLRQLSANLGSRAAAKRNIGKAASASGSKKSSSATSVAVSKANSSYLSYGVDSYTVSVAASANSSDVSSGFFSISEVVSAADAADAAAKAAAASKTERRTRCFECEMCSYIFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00582391;
90% Identity: -
80% Identity: -