Basic Information

Insect: Drosophila navojoa
Gene Symbol: zfh1
Assembly: GCA_001654015.2
Location: NW:48809-54212[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.8e-05 0.0022 17.8 1.7 1 23 150 172 150 172 0.97

2 15 0.00071 0.041 13.9 1.2 3 23 180 200 178 200 0.94

3 15 4.4e-05 0.0025 17.6 0.1 1 23 368 390 368 390 0.98

4 15 0.013 0.73 9.9 0.7 1 23 396 418 396 418 0.98

5 15 1.2e-05 0.00066 19.5 3.1 1 23 449 472 449 472 0.96

6 15 0.00048 0.028 14.4 1.9 1 23 496 518 496 518 0.95

7 15 0.015 0.86 9.7 1.3 1 23 524 547 524 547 0.97

8 15 0.023 1.3 9.1 0.5 3 19 556 572 555 573 0.95

9 15 0.00013 0.0077 16.1 5.6 1 23 582 604 582 604 0.97

10 15 0.035 2 8.5 1.2 2 23 610 631 609 631 0.96

11 15 7.8e-06 0.00045 20.0 1.0 1 23 640 662 640 662 0.98

12 15 0.00019 0.011 15.7 0.5 3 23 670 690 668 690 0.97

13 15 4.8e-05 0.0027 17.5 0.5 1 23 696 718 696 719 0.95

14 15 0.045 2.6 8.2 0.4 1 23 729 751 729 751 0.97

15 15 0.00048 0.027 14.4 0.5 1 23 1280 1302 1280 1302 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.8e-05	0.0022	17.8	1.7	1	23	150	172	150	172	0.97
2	15	0.00071	0.041	13.9	1.2	3	23	180	200	178	200	0.94
3	15	4.4e-05	0.0025	17.6	0.1	1	23	368	390	368	390	0.98
4	15	0.013	0.73	9.9	0.7	1	23	396	418	396	418	0.98
5	15	1.2e-05	0.00066	19.5	3.1	1	23	449	472	449	472	0.96
6	15	0.00048	0.028	14.4	1.9	1	23	496	518	496	518	0.95
7	15	0.015	0.86	9.7	1.3	1	23	524	547	524	547	0.97
8	15	0.023	1.3	9.1	0.5	3	19	556	572	555	573	0.95
9	15	0.00013	0.0077	16.1	5.6	1	23	582	604	582	604	0.97
10	15	0.035	2	8.5	1.2	2	23	610	631	609	631	0.96
11	15	7.8e-06	0.00045	20.0	1.0	1	23	640	662	640	662	0.98
12	15	0.00019	0.011	15.7	0.5	3	23	670	690	668	690	0.97
13	15	4.8e-05	0.0027	17.5	0.5	1	23	696	718	696	719	0.95
14	15	0.045	2.6	8.2	0.4	1	23	729	751	729	751	0.97
15	15	0.00048	0.027	14.4	0.5	1	23	1280	1302	1280	1302	0.98

Sequence Information

Coding Sequence: ATGAACAATCAGGATTATGGCGGCATCCAATGGATACAGCAGCATGCATCCGCGGTGGACTCCGAGGCCGACTTACTGGAAAACGGCGCTACCGATAGCGAGGTAGCGTCCGCCTACTTGGTCAATGGCAATGCGACCGATGAGGATCTCGACCATATGGCGGCCGAGAATCTCATATTTATGGCGCGTGATGGTCAGCTGAGTGAGATAATTGCTGCCAACGAGAGCGGCGGCAGCACAGTCTTAATTACGGATAGCGGAACTGTTTCGTATGCCGAGGCATTTGACGAGGACGCCCAGGTGGTAACTGAAGAGATTATCACAGATGACTGGGTGCAGCACCAAGGCGCCGAGCGCGTTGAGATAGCTGCGGAACAAATCGCGGGCAACAACAGCTCGCAGGAACTGCTGGACATGGAGCAGGACGAGTATACGGCACTGCGACCCTATCCCTGTGACTTCTGCAGCCGGCGTTTCCGCAAAAAGACCAGCCTGAACAATCACATGCTGGCGCATCAGAATGATCGTCCGCATCTGTGTAAATTGTGCGGCGCTCGGTTCTCGCGACGAGCTGAGCTCATCAGTCACTTCAAAGCGCACGCCGAGGCACAGGATGAGGCTGATGCAGCCGATGCGGCGGCAGCAATCAAATTCGAgccgccacagcaacaacagcgccaaATAGACGATCATTTCTATGAGCACGAATGGCCACTGTACCAAGAACAAGAAGATGATCAAGTGCAACATGACCTGCAGCAAATGGAGCAAGACCAGCAAGAGCAGCATGAACaacaggggcagcagcagcagcagctcgtgcTGCCGCAAGCCAGTTATGCAGCCATCAGTGATGTGCCCGCCCCAACTGCCACGCGAGGTCGCATCAGCCGCCTGAAGCCCAAAGAGGAGAGCACTCAGTACATTGTGATTGCCGAAAAACAGACAACGGACGACTTGCAGCCGTACATGGAGTGCGAGGAGCTGCAACCCGCGCTGACGAGCAGCACGTCAATCGAAGCGACGTCAGGGACAGCCAGCGCGCCCGTTGCTGAGGCGGCGGCGACTCCACGGTTTCCGGTGATAGATGAAAGCAAACCGTTCGTGTGTCAGGAATGCGGCTTGGCATTTGCCCGCGAAAAGGCGCTGGTTTCGCACATTAAGAATCATCGCGTCGACTCTCCGTTCGAATGCAATCAATGCCAGGATATGTTCTGGGACAACTACAGCCTGCAGGAGCATCTGAAAACACACCAGTTCGAGGAGAGCAATTCGGAGTATGATCCGGCTTCGGCGGGCGACGACAGCGCTAGCGAGTCGGAGCCGGAACAGCTATACGGCGACTTCTACTGCAGCGAGTGcggcatttcatttcacagGCAGGACCTGCTGCGGCGCCACAccaggcagcagcacaagcagctGACCACGGATGTGCAGAGCGGCGCTGGGGATGCGGACGCCGAGAGTGCCAAAGATGCGCAGCATTGTTGTCACACATGCGGCAAATCGTTTCCCAGCGCCTTGGAGCTGCTCGCCCATGCCGAAGTGCACGCGCGCTTCCCGCCCTTCAAATGCGTTCTATGCGGCGTTAGCTTCTATGAGGAGCAGGCCATCAAGCGGCATTTACACACGCGCCATCCGCATGAGCTGAGACCCAACTCGTGCGTGCTGTGTGGTAAGGAGTGTCGCGATCGCAAGGCCCTGATGAAACACGCCTGGGATCACTCGCGGGAGAAGTGCCACTCGTGCTCAAAGTGCGGCAAGAACTTCCATAACAAGGCGCGACTGAAGCGACACATGGCCTCGCATCGGGACAAGTCGGTCGTATGCGAGGTGTGCCACGAGGAGTTCCCGGACGGGCGAACACTGTCCAATCATCGACATTCGCACAGCACCACCTCGCCGGGCAAACTGTTTCCCTGCCACGAGTGCGGCAAGACCTTCGGGTCGCGCAGCTCCCAGCAGATCCATGTGCGCATCCATACGGGAGAGCGACCATATGGCTGCCACTATTGCTGGAAAGCGTTCGCAGATGGCGGAACGCTGCGCAAACACGAACGCATTCACACTGGCGAGAAGCCCTACGCGTGCTCCGTGTGTCCACGTGCCTTCAATCAGCGCGTCGTGCTGCGCGAGCACATACGCTCGCACCACTCGGGTCTGGATGCTGTGCGAGGGACATATCACTGCACCGTCTGCTCGGCCGATCTGTCCTCGTCCAATGAGCTCATACAGCATCTCATCCAGCACAGCGACACGAACACCGCCAAGCAGCGACAGCCAATCACTGGACCGCGAAAGTATAAGCGTCGCAGGAAACTGCAGCCACATGAGATCGCGCACATGCGAGCGGAGCATAAGGATGGCGAGGATTATGCCAGCGACATGGAGTTCTGTGACCTGGATGTGGAGAATGTGGACGATCTGCTAGAAGGGGCAGACGCGTTGCCAAGCAAAAAGGAGAAGCGCAAGCGTTCAGCTGCCAATCAGCCGAAGTCCGTGACCAATGGGGGCGCAAGTAGCAAAGCCTCTGCGTCGGTCAAGTCAGCCAATAGTAGCTGGGATGACAAGTTCCTGCAGACaaatagcaatggcaatgtCGCCAATAATGATGAGAGCTTCTACCCGATTGATTCGCTCGTGGTGGTCAATGACACCACTTTGCCGGCGGTCAGCCCATCCAGCAATGCACAAGGTGCTTCCAAGTCGCGTCGAGGCGGGGGCAAGCAGGTCGAGAATGGCGATAAGTCCGCAGGAggcggcacagcagcagctgcgactaGCACGGAATCTAGCAAATCCCACGTCGctagcagtcgcagcagcagccgaaagAAGTCCAGTAAGTCGGCCAAGAGTGCTGCCACAGCATCATCCacaccagcagcggcagcagcagcagcttccaACACGGCGAGTAGCTCGCGTCCACGAATGATACACACGGAAAAGTCGCGTGTGCCGCCAGAGAATGCATCGAAGAAGTCGCGTGGAGGCCGCAGCTACATAACGCGCACCAGCACCAGCGAGACCAGCAGCCAGTTGAGTAGCCAGCTGGTCAAGTCGAGTGGCGTGTCCAGCTCGCGAATTGTGGATGACTACGAGATCATATCACCTGCCACCCAACCGCCCAATCAGATCAGTTCCAGTCCGCTGCACatcaagcaggagcaggaacagcagcagcagcgcatccAGTTCATGTTCGATGACAGCCAACTAATCAACACGGCAATGTTGCGGGAGAAGCCCTACGACAAGTTCAATCCAAGCATTGTCAATGATCTCGAGGAGATATTGCGCAGTCCGCTCAAGCATGATCGGAATGCGCGGCTGCGCTTTACCAGCGAATCGTCTACAACGCTACAGTTCCTGCCCGAGTTGGAGCCCAATCTCATCAAGATTGAGCCCACATCACCGGATCTGCGTGACATGGTGGAGAGCCAGCCGCGTGTCAATGCCACAGCTGGCCAAGCGGCCACGCCCGCAACGTCATCCTCATCGTCGGCGGCGCGCACTTCGCGTCACCTGCGACAACTGACGGCCAATGGCTCTGGCAGTCGCGCGGCGTCCAAGCGAAACGCTGGCAAATCCTCAACGTCCTCCGGCTCGAGCACCACGAAGCATAGTAGCAACACATCCTCAACAGAGGCTGTCAGCAAGTCCTACCTGAGCTACGGCGTGGACTCCTACAATGTGGGCGTGACAGCGAGTGCCAACGCGTCGGACGTCAGTTCCGGCTTCTTCTCCATCTCCGAGGTGGTATCCGCTGCCCACGCAGCAGATGCGgccaaggcagcagcagcgagcaaaACGGAGCGCCGGACCCGCTGCTTCGAGTGCGAGATGTGCTCATCCATATTTTCGGATCGggcgcagctgctggagcacatgcacatacacatctaA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSEADLLENGATDSEVASAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGSTVLITDSGTVSYAEAFDEDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKTSLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDEADAADAAAAIKFEPPQQQQRQIDDHFYEHEWPLYQEQEDDQVQHDLQQMEQDQQEQHEQQGQQQQQLVLPQASYAAISDVPAPTATRGRISRLKPKEESTQYIVIAEKQTTDDLQPYMECEELQPALTSSTSIEATSGTASAPVAEAAATPRFPVIDESKPFVCQECGLAFAREKALVSHIKNHRVDSPFECNQCQDMFWDNYSLQEHLKTHQFEESNSEYDPASAGDDSASESEPEQLYGDFYCSECGISFHRQDLLRRHTRQQHKQLTTDVQSGAGDADAESAKDAQHCCHTCGKSFPSALELLAHAEVHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELRPNSCVLCGKECRDRKALMKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCHYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCSADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGEDYASDMEFCDLDVENVDDLLEGADALPSKKEKRKRSAANQPKSVTNGGASSKASASVKSANSSWDDKFLQTNSNGNVANNDESFYPIDSLVVVNDTTLPAVSPSSNAQGASKSRRGGGKQVENGDKSAGGGTAAAATSTESSKSHVASSRSSSRKKSSKSAKSAATASSTPAAAAAAASNTASSSRPRMIHTEKSRVPPENASKKSRGGRSYITRTSTSETSSQLSSQLVKSSGVSSSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRIQFMFDDSQLINTAMLREKPYDKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTLQFLPELEPNLIKIEPTSPDLRDMVESQPRVNATAGQAATPATSSSSSAARTSRHLRQLTANGSGSRAASKRNAGKSSTSSGSSTTKHSSNTSSTEAVSKSYLSYGVDSYNVGVTASANASDVSSGFFSISEVVSAAHAADAAKAAAASKTERRTRCFECEMCSSIFSDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00582391;
90% Identity: iTF_00473204;
80% Identity: -