Deug003101.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila eugracilis
Gene Symbol
-
Assembly
GCA_018153835.1
Location
NW:3055532-3069315[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.9e-05 0.0012 18.8 2.1 1 23 217 239 217 239 0.97
2 18 6.3e-06 0.0004 20.3 0.4 1 23 245 267 245 267 0.97
3 18 0.00093 0.059 13.5 0.9 1 23 273 295 273 295 0.95
4 18 1.3e-05 0.00085 19.3 3.1 1 23 301 323 301 323 0.97
5 18 3e-05 0.0019 18.2 4.7 1 23 329 351 329 351 0.99
6 18 5.6e-05 0.0035 17.4 5.7 1 23 357 379 357 379 0.97
7 18 2.7e-07 1.7e-05 24.6 4.3 1 23 385 407 385 407 0.98
8 18 9.8e-08 6.2e-06 26.0 2.4 1 23 413 435 413 435 0.97
9 18 5.7e-05 0.0036 17.3 6.7 1 23 441 463 441 463 0.97
10 18 9.9e-05 0.0063 16.6 6.5 1 23 469 491 469 491 0.98
11 18 8.9e-06 0.00056 19.9 4.5 1 23 497 519 497 519 0.98
12 18 6.4e-06 0.00041 20.3 8.1 1 23 525 547 525 547 0.98
13 18 5.2e-06 0.00033 20.6 7.6 1 23 553 575 553 575 0.97
14 18 5.8e-07 3.7e-05 23.6 7.7 1 23 581 603 581 603 0.98
15 18 0.00018 0.012 15.7 9.5 1 23 609 632 609 632 0.95
16 18 6.5e-05 0.0041 17.2 0.9 1 23 638 660 638 660 0.98
17 18 0.00071 0.045 13.9 3.4 1 23 670 692 670 692 0.97
18 18 8.1e-06 0.00051 20.0 1.6 1 23 698 721 698 721 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCGGTAGTAGCCCCTGTTGTGACCACTGGTGGGACGACGATCACTTTGGGCGGCCCACCGCCGCTCCCCAAATCGGAGCACAAAGAGGATGGCAAGCCACCCCACGGCATTGAAATGTACAAGGTGAACATCGAGGACATTTCGCAGCTTTTTACTTACCACGAGGTCTTTGGCAAGATCCACGGCGATGTGGTCAATCATCAATTGGCGGCGGCCCATGGAGGTCAGTTGCCACCACCTCCACCGCTACCGCCACAGGTCAGCAGTCATGCGGCgagtgcagcagcagccgcagcagcagcatccacTAACAATGCCGCCGTGGCAGCGGCAATGGCATCAGCGAATGCAGCAGCGGTCGCGGCGGCAGCTGCATCGGCGGGGGGACTACCGCCGGCCACCAGCGGCAATGGAGGCCAGCAGGTGACGGTGACGACGACCAGCAGCTCGACAAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGGCAATGGCGGCGGGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCCATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGACGCTACCACAGCGAACGGAAGCCGTTCATGTGCCAGGTGTGCGGCCAGGGGTTCACCACGTCGCAGGATTTGACGCGCCACGGCAAGATTCACATTGGCGGGCCCATGTTCACCTGTATCGTGTGCTTCAATGTGTTCGCGAACAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCACCTGGACAATCACTTCCGCTCGCACACGGGCGAAACGCCCTTTCGTTGCCAGTACTGCGCCAAGACGTTCACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGCGATGTCTGCGGCAAGAAATATACGCGCAAGGAGCACCTAGCCAACCATATGCGATCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAAAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTTTGGCATACAGGCGAGACGCCGCACAGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCACTTGCTAAACCACGTGCGCCAGCACACGGGAGAGTCGCCGCACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACGTACTGCACTAAGACGTTCACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTTACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTTACACGGAAGGAGCACCTCAACAACCACATGCGCCAGCATTCGAGTGACAATCCGCATTGCTGCAATGTTTGCAACAAGCCGTTTACGCGCAAGGAGCACCTGATCAACCATATGTCGCGGTGCCACACCGGCGACCGGCCCTTCACCTGCGAGACGTGCGGCAAGTCGTTCCCGCTCAAGGGCAATCTTCTCTTCCATCAGCGCAGCCACACCAAGGGTCAGGAGATGGAGCGGCCCTTCGCCTGCGAGAAATGTCCCAAGAACTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGTGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATCCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAGATCACGGCGGGAGCGGCGGGCGGAGCCGGTGCAGTGCAGCTTACCCCAGGCCTGGTGCCCCTGGTCACCTCCACGCTCATCTCGCATAATGCGGTTGCCCAGCAGCAGTCGCAGAAACAGCAAGCCgccgcagctgcagcagccCAGCAACAGGCCgccgcagcagctgctgcccaACAGCAAGCAGCCCAGCAACAGGCGGCTGCTGCacatcagcagcatcagcaacaagTAGCCGcccagcatcagcaacaggcCGCAGTGGCTgcccatcagcagcagcaacagcagttgcagcagcagcaacaactgctGCAGTTGTCCATCCAGCAGGCAGCTCACCATcatcagcaggagcagcatcgccaacaacagcaacagcaacatcagcagcaacaacaacagcaacatcatcagcagcaacagcagggtCACCCTCAGGCCccgccgccgcagcagcaacagcagccgccgCCCATCGCCCTGATCAGCGATCCAAGTGCTCTGGCACGCGCGGCTATTCAGCTACAGCATCTGCCTGCGAACGTGGAACAGCACCCTGTTGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQVSSHAASAAAAAAAASTNNAAVAAAMASANAAAVAAAAASAGGLPPATSGNGGQQVTVTTTSSSTSSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLVTSTLISHNAVAQQQSQKQQAAAAAAAQQQAAAAAAAQQQAAQQQAAAAHQQHQQQVAAQHQQQAAVAAHQQQQQQLQQQQQLLQLSIQQAAHHHQQEQHRQQQQQQHQQQQQQQHHQQQQQGHPQAPPPQQQQQPPPIALISDPSALARAAIQLQHLPANVEQHPVVY