Derc002889.1
Basic Information
- Insect
- Drosophila ercepeae
- Gene Symbol
- -
- Assembly
- GCA_018150545.1
- Location
- JAECWL010000189.1:14640577-14649558[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 1.6e-05 0.0011 19.1 2.1 1 23 222 244 222 244 0.97 2 18 5.2e-06 0.00036 20.6 0.4 1 23 250 272 250 272 0.97 3 18 0.00076 0.053 13.8 0.9 1 23 278 300 278 300 0.95 4 18 1.1e-05 0.00077 19.6 3.1 1 23 306 328 306 328 0.97 5 18 2.5e-05 0.0017 18.5 4.7 1 23 334 356 334 356 0.99 6 18 4.6e-05 0.0032 17.6 5.7 1 23 362 384 362 384 0.97 7 18 2.2e-07 1.6e-05 24.9 4.3 1 23 390 412 390 412 0.98 8 18 8e-08 5.6e-06 26.3 2.4 1 23 418 440 418 440 0.97 9 18 4.7e-05 0.0033 17.6 6.7 1 23 447 469 447 469 0.97 10 18 8.1e-05 0.0057 16.9 6.5 1 23 475 497 475 497 0.98 11 18 7.3e-06 0.00051 20.2 4.5 1 23 503 525 503 525 0.98 12 18 5.3e-06 0.00037 20.6 8.1 1 23 531 553 531 553 0.98 13 18 4.3e-06 0.0003 20.9 7.6 1 23 559 581 559 581 0.97 14 18 4.8e-07 3.3e-05 23.9 7.7 1 23 587 609 587 609 0.98 15 18 0.00015 0.01 16.0 9.5 1 23 615 638 615 638 0.95 16 18 5.5e-05 0.0038 17.4 0.9 1 23 644 666 644 666 0.98 17 18 0.00058 0.04 14.2 3.4 1 23 676 698 676 698 0.97 18 18 6.6e-06 0.00046 20.3 1.6 1 23 704 727 704 727 0.96
Sequence Information
- Coding Sequence
- ATGCAACACGTGAGCGCTGCCAGCTCGGTGCCATCGGTAGTAGCCCCCGTAGTGACCACTGGTGGTACAACGATCACCTTGGGCGGACCACCACACACTCTTCCCAAGTCGGAGCACAAAGAGGATGGCAAGCCGCCGCACGGCATCGAGATGTACAAGGTCAATATCGAGGACATCTCCCAGCTGTTCACCTACCATGAAGTTTTTGGAAAGATACACGGCGATGTGGTGAATCACCAATTGGCGGCGGCCCACGGGGGTCAGCTACCGCCACCGCCGCCACTCCCGCCGCAGGCCAGCAGTCATGCGGCGAGTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGGAGGACTACCGCCCGCCACCAGTGGCAATGGGGGCCAAGTGACTGTGACGACGACGAGCAGCTCGACAGCCAGCAGCAGCGGCGGCGCTGGGAGCACTACCAGTGGTGGCACCACGACCACGGCGGGTGAGTTGCTAATGCCTAAAATGGAGGGCGGCATACATAACGTGGACGGCAGCGGCGGGCAGTCGAACGTGGCGCTGGCGCCGGACGGGACGCCGATTGCGACGGGGACGCACGTCTGCGACATCTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAGCCGTTCATGTGCCAGGTGTGCGGCCAGGGCTTCACCACGTCCCAGGATCTGACCCGGCACGGCAAGATCCACATTGGCGGGCCGATGTTCACCTGTATTGTGTGCTTTAATGTTTTCGCTAACAACACGAGTCTGGAGCGGCACATGAAGCGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGGTCGCACACGGGCGAAACGCCCTTTCGTTGCCAGTACTGCGCCAAGACGTTCACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACCCCCCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGTTTTAGCCGCAAGGAGCACTTCACCAACCACATACTCTGGCATACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAACACTTGCTCAACCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATACGGCAGCACACGGGTGAGACACCGTTCAAGTGCACCTACTGCACGAAAGCGTTTACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACGTACTGCACCAAGACGTTCACGCGCAAGGAGCATTTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCATCGCTGCTCCTACTGCAAGAAGACGTTCACGCGCAAGGAGCACTTGACGAACCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTCACGCGGAAGGAGCACCTCAACAACCATATGCGCCAGCACTCCAGTGACAATCCGCACTGCTGCAATGTCTGCAACAAGCCATTCACGCGCAAGGAGCACCTGATCAACCACATGTCCCGATGCCACACCGGCGACCGGCCCTTCACCTGCGACACCTGCGGCAAGTCGTTCCCCTTGAAGGGTAATCTGCTCTTCCATCAGCGCAGCCATACCAAGGGCCAGGAGATGGAGCGTCCCTTTGCCTGTGAGAAGTGTCCCAAGAACTTTATCTGCAAGGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCCCAAATACCGGCTGGTGTGCTGACACAAGTCAAGCAGGAGGTGAAACCGATCATAATTCCCCACCATTCGGCGGCAACCACCACGATGCACACAATCCAGCAGATCACGGCGGGAGCTGCCACCCAACTGACCCCGGGTCTTGTGCCGCTGAGTATTATTTTCCACAAGGACCTCTATTTGTTGTGA
- Protein Sequence
- MQHVSAASSVPSVVAPVVTTGGTTITLGGPPHTLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQASSHAASXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGGLPPATSGNGGQVTVTTTSSSTASSSGGAGSTTSGGTTTTAGELLMPKMEGGIHNVDGSGGQSNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCDTCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSAATTTMHTIQQITAGAATQLTPGLVPLSIIFHKDLYLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00505532;
- 90% Identity
- iTF_00507738;
- 80% Identity
- -