Basic Information

Insect: Drosophila atripex
Gene Symbol: -
Assembly: GCA_035045925.1
Location: JAWNOP010000070.1:2095188-2101313[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.1e-05 0.0016 18.8 2.1 1 23 224 246 224 246 0.97

2 18 6.8e-06 0.00053 20.3 0.4 1 23 252 274 252 274 0.97

3 18 0.001 0.078 13.5 0.9 1 23 280 302 280 302 0.95

4 18 1.4e-05 0.0011 19.3 3.1 1 23 308 330 308 330 0.97

5 18 3.3e-05 0.0025 18.2 4.7 1 23 336 358 336 358 0.99

6 18 6e-05 0.0046 17.4 5.7 1 23 364 386 364 386 0.97

7 18 2.9e-07 2.3e-05 24.6 4.3 1 23 392 414 392 414 0.98

8 18 1.1e-07 8.1e-06 26.0 2.4 1 23 420 442 420 442 0.97

9 18 6.1e-05 0.0047 17.3 6.7 1 23 449 471 449 471 0.97

10 18 0.00011 0.0083 16.6 6.5 1 23 477 499 477 499 0.98

11 18 9.5e-06 0.00074 19.9 4.5 1 23 505 527 505 527 0.98

12 18 6.9e-06 0.00053 20.3 8.1 1 23 533 555 533 555 0.98

13 18 5.6e-06 0.00043 20.6 7.6 1 23 561 583 561 583 0.97

14 18 6.3e-07 4.9e-05 23.6 7.7 1 23 589 611 589 611 0.98

15 18 0.0002 0.015 15.7 9.5 1 23 617 640 617 640 0.95

16 18 7.2e-05 0.0055 17.1 0.9 1 23 646 668 646 668 0.98

17 18 0.00076 0.059 13.9 3.4 1 23 678 700 678 700 0.97

18 18 8.7e-06 0.00067 20.0 1.6 1 23 706 729 706 729 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.1e-05	0.0016	18.8	2.1	1	23	224	246	224	246	0.97
2	18	6.8e-06	0.00053	20.3	0.4	1	23	252	274	252	274	0.97
3	18	0.001	0.078	13.5	0.9	1	23	280	302	280	302	0.95
4	18	1.4e-05	0.0011	19.3	3.1	1	23	308	330	308	330	0.97
5	18	3.3e-05	0.0025	18.2	4.7	1	23	336	358	336	358	0.99
6	18	6e-05	0.0046	17.4	5.7	1	23	364	386	364	386	0.97
7	18	2.9e-07	2.3e-05	24.6	4.3	1	23	392	414	392	414	0.98
8	18	1.1e-07	8.1e-06	26.0	2.4	1	23	420	442	420	442	0.97
9	18	6.1e-05	0.0047	17.3	6.7	1	23	449	471	449	471	0.97
10	18	0.00011	0.0083	16.6	6.5	1	23	477	499	477	499	0.98
11	18	9.5e-06	0.00074	19.9	4.5	1	23	505	527	505	527	0.98
12	18	6.9e-06	0.00053	20.3	8.1	1	23	533	555	533	555	0.98
13	18	5.6e-06	0.00043	20.6	7.6	1	23	561	583	561	583	0.97
14	18	6.3e-07	4.9e-05	23.6	7.7	1	23	589	611	589	611	0.98
15	18	0.0002	0.015	15.7	9.5	1	23	617	640	617	640	0.95
16	18	7.2e-05	0.0055	17.1	0.9	1	23	646	668	646	668	0.98
17	18	0.00076	0.059	13.9	3.4	1	23	678	700	678	700	0.97
18	18	8.7e-06	0.00067	20.0	1.6	1	23	706	729	706	729	0.96

Sequence Information

Coding Sequence: ATGCAACACGTGAGCGCTGCCAGCTCGGTGCCATCGGTAGTAGCCCCCGTAGTGACCACTGGTGGTACGACGATCACCTTGGGCGGACCCCCACATACGCTCCCCAAATCGGAGCACAAAGACGATGGCAAGCCGCCGCACGGCTTGGAGATGTACAAGGTTAATATCGAGGACATCTCACAGCTCTTCACCTACCACGAAGTTTTTGGCAAGATACACGGCGATGTGGTGAATCACCAATTGGCGGCTGCCCACGGTGGCCAGTTACCGCCCCCGCCGCCACTACCGCCGCAGGCCACCAGTCATGCGGCGAGTGCGGCGgccgcagcagcggcagcatcgACAAATAACGCCGCCGTTGCGGCAGTAATGGCATCCGCCAatgcagcggcggcggcagcagcagctgcatcAGCAGCGGGAGGCGGCGGGGGACTACCGCCAGCTACCAGCGGTAACGGTGGCCAAGTGACTGTGACGACGACGAGCAGCTCGACGGCCAGTAGCAGCGGCGGCGCTGGGAGCACTACCAGCGGCACTACGACCACGGCGGGTGAGTTGCTAATGCCTAAAATGGAGGGAGGCATACATAACGTGgacggcagcggcggcggcgggcaGTCGAATGTGGCGCTGGCGCCGGACGGTACGCCGATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTTCGGTACCAGCTGATCGTACACCGGCGCTATCACAGCGAACGTAAACCGTTTATGTGCCAGGTGTGCGGTCAGGGCTTCACCACGTCCCAGGATTTGACCCGCCACGGCAAGATTCATATTGGCGGTCCGATGTTCACCTGTATCGTGTGCTTTAATGTTTTCGCTAACAACACGAGTCTGGAGCGGCACATGAAGCGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACATTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGGTCGCACACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGgtCAAACCCCCCACCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAACCACATACTCTGGCATACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAACACTTGCTCAACCACGTGCGCCAGCACACGGGAGAGTCGCCGCACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATCCGGCAGCACACGGGTGAGACACCGTTCAAGTGCACCTACTGCACGAAAGCGTTTACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACCAAGACGTTCACGCGCAAGGAGCATTTGACGAATCATGTGCGCCAGCATACGGGCGACTCCCCGCATCGATGCTCCTACTGCAAGAAGACGTTCACGCGCAAGGAGCATTTGACGAACCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTCACGCGGAAGGAGCACCTCAACAACCACATGCGTCAGCACTCTAGCGACAATCCGCACTGCTGCAATGTCTGCAACAAGCCATTCACGCGCAAGGAACACCTGATCAACCACATGTCTCGGTGCCACACCGGCGACCGGCCCTTCACCTGCGACACCTGCGGCAAGTCGTTCCCATTGAAGGGTAATCTGCTCTTCCACCAGCGCAGCCATACCAAGGGCCAGGAGATGGAGCGACCCTTCGCCTGTGAGAAGTGCCCCAAGAACTTCATCTGCAAGGGTCACTTGGTCTCGCATATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAGGTGAAACCGATCATAATTCCCCACCACTCGGCGGCGACGACCACGATGCACACCATCCAGCAGATAACGGCGGGCGCTGCAACGCAATTGACACCGGGTCTCGTGCCGCTGGTCACCTCGACGCTCATCTCGCATAACCCACAATCGCAAAAGCAGcaagcagccgccgcagcGGTTGCCCAGCAACAGGCGGCCGCTGCAGCTGCCGCCCAACAGCAGGCGGCCCAGCAACAGGCAGCAGCGGCCcatcagcagcaccagcagcaagtGGCCGCCGcccatcagcagcaacagcaagcgGCAGCAGTCCAGGCGGCtcaccaacaacagcagcaacagctccagcagcagcagcagttgcttCAGCTTTCCATTCAACAGGCGGCGCACCATCACCAACAGGAGCAGCATcgccaacagcagcaacaacaacagcagcagcaacaccagcagcagcagcaacaacagcagcagcaccatcagcaacagcaaggcCATCCACAGGCACCGCCgccccagcagcaacagcagccaccTCCGCAGGTTCCAATTGCATTGATAAGCGATCCAAGCGCCCTGGCACGTGCCGCCATGCAGCTGCAACATTTGCCGGCGAATGTGGAGCAACACCCGGTTGTTTACTAA
Protein Sequence: MQHVSAASSVPSVVAPVVTTGGTTITLGGPPHTLPKSEHKDDGKPPHGLEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQVTVTTTSSSTASSSGGAGSTTSGTTTTAGELLMPKMEGGIHNVDGSGGGGQSNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCDTCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSAATTTMHTIQQITAGAATQLTPGLVPLVTSTLISHNPQSQKQQAAAAAVAQQQAAAAAAAQQQAAQQQAAAAHQQHQQQVAAAHQQQQQAAAVQAAHQQQQQQLQQQQQLLQLSIQQAAHHHQQEQHRQQQQQQQQQQHQQQQQQQQQHHQQQQGHPQAPPPQQQQQPPPQVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505532;
90% Identity: iTF_00507738;
80% Identity: iTF_00476054;