Basic Information

Insect: Drosophila seguyi
Gene Symbol: -
Assembly: GCA_008042675.1
Location: VNJU01000897.1:60935-67414[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2e-05 0.0015 18.8 2.1 1 23 226 248 226 248 0.97

2 18 6.7e-06 0.00049 20.3 0.4 1 23 254 276 254 276 0.97

3 18 0.00099 0.072 13.5 0.9 1 23 282 304 282 304 0.95

4 18 1.4e-05 0.001 19.3 3.1 1 23 310 332 310 332 0.97

5 18 3.2e-05 0.0024 18.2 4.7 1 23 338 360 338 360 0.99

6 18 5.9e-05 0.0043 17.3 5.7 1 23 366 388 366 388 0.97

7 18 2.9e-07 2.1e-05 24.6 4.3 1 23 394 416 394 416 0.98

8 18 1e-07 7.5e-06 26.0 2.4 1 23 422 444 422 444 0.97

9 18 6e-05 0.0044 17.3 6.7 1 23 451 473 451 473 0.97

10 18 0.00011 0.0077 16.6 6.5 1 23 479 501 479 501 0.98

11 18 9.4e-06 0.00068 19.9 4.5 1 23 507 529 507 529 0.98

12 18 6.8e-06 0.0005 20.3 8.1 1 23 535 557 535 557 0.98

13 18 5.5e-06 0.0004 20.6 7.6 1 23 563 585 563 585 0.97

14 18 6.2e-07 4.5e-05 23.6 7.7 1 23 591 613 591 613 0.98

15 18 0.00019 0.014 15.7 9.5 1 23 619 642 619 642 0.95

16 18 6.9e-05 0.005 17.1 0.9 1 23 648 670 648 670 0.98

17 18 0.00075 0.055 13.9 3.4 1 23 680 702 680 702 0.97

18 18 8.6e-06 0.00062 20.0 1.6 1 23 708 731 708 731 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2e-05	0.0015	18.8	2.1	1	23	226	248	226	248	0.97
2	18	6.7e-06	0.00049	20.3	0.4	1	23	254	276	254	276	0.97
3	18	0.00099	0.072	13.5	0.9	1	23	282	304	282	304	0.95
4	18	1.4e-05	0.001	19.3	3.1	1	23	310	332	310	332	0.97
5	18	3.2e-05	0.0024	18.2	4.7	1	23	338	360	338	360	0.99
6	18	5.9e-05	0.0043	17.3	5.7	1	23	366	388	366	388	0.97
7	18	2.9e-07	2.1e-05	24.6	4.3	1	23	394	416	394	416	0.98
8	18	1e-07	7.5e-06	26.0	2.4	1	23	422	444	422	444	0.97
9	18	6e-05	0.0044	17.3	6.7	1	23	451	473	451	473	0.97
10	18	0.00011	0.0077	16.6	6.5	1	23	479	501	479	501	0.98
11	18	9.4e-06	0.00068	19.9	4.5	1	23	507	529	507	529	0.98
12	18	6.8e-06	0.0005	20.3	8.1	1	23	535	557	535	557	0.98
13	18	5.5e-06	0.0004	20.6	7.6	1	23	563	585	563	585	0.97
14	18	6.2e-07	4.5e-05	23.6	7.7	1	23	591	613	591	613	0.98
15	18	0.00019	0.014	15.7	9.5	1	23	619	642	619	642	0.95
16	18	6.9e-05	0.005	17.1	0.9	1	23	648	670	648	670	0.98
17	18	0.00075	0.055	13.9	3.4	1	23	680	702	680	702	0.97
18	18	8.6e-06	0.00062	20.0	1.6	1	23	708	731	708	731	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCTAGCTCGGTGCCATCAGTTGTAGCCCCCGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGCCCACCACCGCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATTGAGATGTACAAGGTTAACATCGAGGACATCTCTCAGCTCTTCACCTATCACGAGGTCTTTGGCAAGATCCATGGCGATGTTGTGAATCATCAATTGGCGGCGGCCCATGGAGGCCAgctgccaccaccgccgccccTTCCACCGCAGGCCACTAGTCATGCGGCCagtgcggcagcagcagccgcagcagcgtCCACGAATAATGCTGCTGTGGCGGCAGTGATGGCCTCCGCcaatgcggcggcggcggcagcagcggctgcatCGGCAGCGGGCGGCGGTGGAGGACTGCCACCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTGACGACGACCAGCAGCTCGACGGCCAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGgcaatggcggcggcggcaacggcggGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCAATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAACCGTTCATGTGCCAAGTGTGTGGCCAGGGCTTCACCACGTCGCAGGATTTGACGCGCCACGGCAAGATTCACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCGAACAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGTGCGAAGACGTTTACGCGCAAGGAGCACATGGTGAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGTGATGTCTGCGGCAAGAAATATACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGTTTTAGCCGCAAGGAGCATTTCACCAATCACATACTCTGGCACACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGAAAGGAGCATTTGCTTAACCACGTGCGCCAGCATACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACTTTCACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAACACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGGCTCCACACGGGCGACTCGCCCCACAAGTGCGAGTACTGCCAGAAGACGTTTACGCGGAAGGAGCATCTCAACAACCATATGCGCCAGCATTCAAGCGACAATCCGCACTGCTGCAATGTCTGCAATAAGCCGTTCACGCGCAAGGAGCACCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGGCCCTTCACCTGCGAGACATGCGGCAAATCTTTCCCGCTCAAGGGCAACCTGCTCTTCCATCAGCGCAGTCACACCAAGGGCCAGGAGATGGAGAGGCCCTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGTGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACAACGATGCACACCATCCAGCAGATAACCGCTGGTGCGGcgggcggtgccggtgccgtTCAGTTAACGCCGGGCCTGGTGCCCCTGGTCACCTCAACGCTCATCTCGCACAATGccgccgcccagcagcagtcgcagaaGCAACAGgcagccgccgctgcagcggcCCAGCAAcaggctgcagcggcagcagcggctcaGCAGCAGGCTGCTCAGCAACAGGCGGCGGCCGCCCatcagcaacaccagcagcaagTGGCGGcacagcatcagcaacaggCGGCAGTGGCTgcccatcagcagcagcaacagcagttgcagcagcagcagcaattgctGCAGTTGTCCATCCAGCAGGCGGCTCACCATcatcagcaggagcagcatcgtcagcagcagcagcagcagcaacaccagcaacagcagcagcagcaacaacaacagcagcaacaacaccatcagcagcagcagcatccgggccaggcgccgccgccgcagcaacAGCCGCCACCAGGAGTGCCCATCGCCTTGATAAGTGATCCCAGTGCTTTGGCCCGCGCCGCCATGCAGCTGCAGCATCTGCCAGCGAACGTGGAGCAACACCCGGTTGTTTACTAA
Protein Sequence: MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQQVTVTTTSSSTASSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLVTSTLISHNAAAQQQSQKQQAAAAAAAQQQAAAAAAAQQQAAQQQAAAAHQQHQQQVAAQHQQQAAVAAHQQQQQQLQQQQQLLQLSIQQAAHHHQQEQHRQQQQQQQHQQQQQQQQQQQQQHHQQQQHPGQAPPPQQQPPPGVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505532;
90% Identity: iTF_00507738;
80% Identity: iTF_00613613; iTF_00561887;