Dbia012713.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila biarmipes
Gene Symbol
-
Assembly
GCA_018148935.1
Location
JAECYG010000047.1:20683597-20690792[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.7e-05 0.001 19.1 2.1 1 23 204 226 204 226 0.97
2 18 5.8e-06 0.00034 20.6 0.4 1 23 232 254 232 254 0.97
3 18 0.00085 0.051 13.8 0.9 1 23 260 282 260 282 0.95
4 18 1.2e-05 0.00073 19.6 3.1 1 23 288 310 288 310 0.97
5 18 2.8e-05 0.0017 18.5 4.7 1 23 316 338 316 338 0.99
6 18 5.1e-05 0.003 17.7 5.7 1 23 344 366 344 366 0.97
7 18 2.5e-07 1.5e-05 24.9 4.3 1 23 372 394 372 394 0.98
8 18 8.9e-08 5.3e-06 26.3 2.4 1 23 400 422 400 422 0.97
9 18 5.2e-05 0.0031 17.6 6.7 1 23 429 451 429 451 0.97
10 18 9e-05 0.0054 16.9 6.5 1 23 457 479 457 479 0.98
11 18 8.1e-06 0.00048 20.2 4.5 1 23 485 507 485 507 0.98
12 18 5.8e-06 0.00035 20.6 8.1 1 23 513 535 513 535 0.98
13 18 4.7e-06 0.00028 20.9 7.6 1 23 541 563 541 563 0.97
14 18 5.3e-07 3.2e-05 23.9 7.7 1 23 569 591 569 591 0.98
15 18 0.00017 0.0099 16.1 9.5 1 23 597 620 597 620 0.95
16 18 5.9e-05 0.0035 17.5 0.9 1 23 626 648 626 648 0.98
17 18 0.00064 0.038 14.2 3.4 1 23 658 680 658 680 0.97
18 18 7.3e-06 0.00044 20.3 1.6 1 23 686 709 686 709 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCTAGCTCGGTGCCATCAGTAGTAGCCCCTGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGCCCACCGCCGCTCCCCAAATCGGAGCACAAAGAGGATGGCAAGCCACCGCACGGCATCGAGATGTACAAGGTGAACATCGAGGACATTTCGCAGCTCTTTACCTACCACGAGGTCTTTGGCAAGATCCACGGCGATGTGGTCAACCATCAATTGGCGGCGGCCCACGGAGGGCAGCTGCCACCTCCTCCGCCGCTGCCGCCGCAGGTCACCAGCCATGCGGCGAGTGCAGCGGCAGCCGCGGCAGCAGCCAGCGGCCGCGGCGGCGGCTGCTTCGGCGGGGGAGGACTACCGCCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTGACGACGACCAGCAGCTCGACAAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGGAAACGGCGGCAATGGCGGCGGGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCCATTGCGACGGGGACGCACGTCTGCGACATCTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAGCCGTTCATGTGCCAGGTGTGCGGCCAGGGGTTCACCACATCGCAGGATTTGACGCGCCACGGCAAGATCCACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCGAACAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCACCTGGACAATCACTTCCGCTCGCACACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTCACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGATCGCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAACCACATACTCTGGCATACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCACTTGCTCAACCACGTGCGCCAGCACACGGGAGAGTCGCCGCACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACGTACTGCACTAAGACGTTCACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTTACGCGGAAGGAGCACCTGACGAATCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAATGCGAGTACTGCCAGAAGACGTTCACGCGGAAGGAGCACCTCAACAATCACATGCGCCAGCACTCGAGCGACAATCCGCATTGCTGCAACGTTTGCAACAAGCCGTTTACGCGCAAGGAGCACCTGATCAACCACATGTCGCGGTGCCACACCGGCGACCGGCCCTTCACCTGCGAGACGTGCGGCAAGTCGTTCCCGCTCAAGGGCAACCTGCTCTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGATGGAGCGACCATTTGCCTGCGAGAAGTGCCCCAAGAACTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGTGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATTCAGCAGATCACGGCGGGAGCGGCGGGCGGAGCCGGAGCACTGCGCTCAGTGCATCGTACGGGTCCGACGACCATTCGACTCGTCCACTCTTCTCGCTAG
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQVTSHAASAAAAAAAASGRGGGCFGGGGLPPATSGNGGQQVTVTTTSSSTSSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGNGGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGALRSVHRTGPTTIRLVHSSR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00505532;
90% Identity
iTF_00507738;
80% Identity
-