Dana010916.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ananassae
Gene Symbol
-
Assembly
GCA_017639315.1
Location
CM029942.1:35600602-35607240[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.5e-05 0.0012 19.1 2.1 1 23 224 246 224 246 0.97
2 18 5.1e-06 0.00039 20.6 0.4 1 23 252 274 252 274 0.97
3 18 0.00075 0.057 13.8 0.9 1 23 280 302 280 302 0.95
4 18 1.1e-05 0.00082 19.6 3.1 1 23 308 330 308 330 0.97
5 18 2.4e-05 0.0019 18.5 4.7 1 23 336 358 336 358 0.99
6 18 4.5e-05 0.0034 17.7 5.7 1 23 364 386 364 386 0.97
7 18 2.2e-07 1.7e-05 24.9 4.3 1 23 392 414 392 414 0.98
8 18 7.8e-08 6e-06 26.3 2.4 1 23 420 442 420 442 0.97
9 18 4.6e-05 0.0035 17.6 6.7 1 23 449 471 449 471 0.97
10 18 7.9e-05 0.0061 16.9 6.5 1 23 477 499 477 499 0.98
11 18 7.1e-06 0.00054 20.2 4.5 1 23 505 527 505 527 0.98
12 18 5.1e-06 0.00039 20.6 8.1 1 23 533 555 533 555 0.98
13 18 4.2e-06 0.00032 20.9 7.6 1 23 561 583 561 583 0.97
14 18 4.7e-07 3.6e-05 23.9 7.7 1 23 589 611 589 611 0.98
15 18 0.00015 0.011 16.0 9.5 1 23 617 640 617 640 0.95
16 18 5.3e-05 0.0041 17.4 0.9 1 23 646 668 646 668 0.98
17 18 0.00057 0.043 14.2 3.4 1 23 678 700 678 700 0.97
18 18 6.5e-06 0.00049 20.3 1.6 1 23 706 729 706 729 0.96

Sequence Information

Coding Sequence
ATGCAACACGTGAGCGCTGCCAGCTCGGTGCCATCGGTAGTAGCCCCCGTAGTGACCACTGGTGGTACAACGATCACCTTGGGCGGACCCCCACACACGCTCCCCAAATCGGAGCACAAAGACGATGGCAAGCCGCCGCACGGCTTGGAGATGTACAAGGTCAATATCGAGGACATCTCACAGCTCTTCACCTACCACGAAGTTTTTGGCAAAATCCACGGCGATGTTGTGAATCATCAATTGGCGGCTGCCCATGGTGGCCAGTTACCGCCCCCGCCGCCACTACCGCCGCAGGCCACCAGTCATGCGGCGAGTGCGGCGGCCGCAGCAGCGGCAGCATCCACAAATAATGCCGCTGTGGCGGCAGTAATGGCCTCCGCCAATGCAGCGGCGGCAGCAGCAGCAGCCGCATCGGCAGCGGGAGGCGGCGGGGGACTACCGCCAGCTACCAGCGGAAATGGTGGCCAAGTGACTGTGACGACGACGAGCAGCTCGACGGCCAGTAGCAGCGGCGGCGCTGGAAGTACTACCAGCGGCACTACGACCACGGCGGGTGAGTTGCTAATGCCTAAAATGGAGGGAGGCATACATAACGTGGACGGCAGCGGCGGCGGCGGGCAGTCGAACGTGGCGCTGGCGCCGGACGGTACGCCGATTGCGACGGGGACGCACGTTTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTACACCGGCGCTATCACAGCGAACGTAAACCGTTTATGTGCCAGGTGTGCGGTCAGGGCTTCACAACGTCCCAGGATTTGACCCGCCACGGCAAGATACATATTGGCGGTCCGATGTTCACCTGTATCGTGTGCTTTAATGTTTTTGCTAACAACACGAGTCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACATTTGCCCGAAAAGAGCATCTGGACAATCACTTTCGGTCGCATACGGGCGAAACGCCATTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACCCCCCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAACCACATACTCTGGCATACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAACACTTGCTCAACCACGTGCGCCAGCACACGGGAGAGTCGCCGCACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATCCGGCAGCACACGGGTGAGACACCGTTCAAGTGCACCTACTGCACGAAAGCGTTTACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACCAAGACGTTCACGCGCAAGGAGCATTTGACGAATCATGTGCGCCAGCATACGGGCGACTCCCCGCATCGCTGCTCCTACTGCAAGAAGACCTTTACGCGCAAGGAGCATTTGACGAATCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTCACGCGGAAGGAGCACCTCAACAACCATATGCGCCAGCACTCTAGCGACAATCCGCACTGCTGCAATGTCTGCAACAAGCCATTCACGCGCAAGGAACACCTGATCAACCACATGTCCCGATGCCACACCGGCGACCGGCCCTTCACCTGCGACACATGCGGCAAGTCGTTCCCATTGAAGGGTAATCTGCTCTTCCACCAGCGCAGCCATACCAAGGGCCAGGAGATGGAGCGACCCTTTGCCTGTGAGAAGTGCCCCAAGAACTTTATCTGCAAGGGTCACTTGGTCTCGCATATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAGGTGAAACCGATCATAATTCCCCACCACTCGGCGGCGACGACCACGATGCACACCATCCAGCAGATAACGGCTGGAGCTGCAACGCAATTGACACCGGGTCTCGTGCCGCTGGAGTAG
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPHTLPKSEHKDDGKPPHGLEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQVTVTTTSSSTASSSGGAGSTTSGTTTTAGELLMPKMEGGIHNVDGSGGGGQSNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCDTCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSAATTTMHTIQQITAGAATQLTPGLVPLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00505532;
90% Identity
iTF_00507738;
80% Identity
iTF_00550371; iTF_00481662;