Dser002387.1
Basic Information
- Insect
- Drosophila serrata
- Gene Symbol
- -
- Assembly
- GCA_002093755.1
- Location
- NW:420980-428832[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 1.9e-05 0.0013 18.8 2.1 1 23 225 247 225 247 0.97 2 18 6.4e-06 0.00042 20.3 0.4 1 23 253 275 253 275 0.97 3 18 0.00095 0.061 13.5 0.9 1 23 281 303 281 303 0.95 4 18 1.4e-05 0.00088 19.3 3.1 1 23 309 331 309 331 0.97 5 18 3.1e-05 0.002 18.2 4.7 1 23 337 359 337 359 0.99 6 18 5.6e-05 0.0037 17.3 5.7 1 23 365 387 365 387 0.97 7 18 2.8e-07 1.8e-05 24.6 4.3 1 23 393 415 393 415 0.98 8 18 9.9e-08 6.4e-06 26.0 2.4 1 23 421 443 421 443 0.97 9 18 5.8e-05 0.0037 17.3 6.7 1 23 449 471 449 471 0.97 10 18 0.0001 0.0065 16.6 6.5 1 23 477 499 477 499 0.98 11 18 9e-06 0.00058 19.9 4.5 1 23 505 527 505 527 0.98 12 18 6.5e-06 0.00042 20.3 8.1 1 23 533 555 533 555 0.98 13 18 5.3e-06 0.00034 20.6 7.6 1 23 561 583 561 583 0.97 14 18 5.9e-07 3.8e-05 23.6 7.7 1 23 589 611 589 611 0.98 15 18 0.00019 0.012 15.7 9.5 1 23 617 640 617 640 0.95 16 18 6.6e-05 0.0043 17.1 0.9 1 23 646 668 646 668 0.98 17 18 0.00072 0.047 13.9 3.4 1 23 678 700 678 700 0.97 18 18 8.2e-06 0.00053 20.0 1.6 1 23 706 729 706 729 0.96
Sequence Information
- Coding Sequence
- ATGCAGCACGTGAGCGCTGCCAGCTCAGTGCCATCAGTTGTAGCTCCCGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGCCCACCACCGCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATTGAGATGTACAAGGTGAACATCGAGGACATCTCTCAGCTCTTTACCTATCACGAGGTCTTTGGCAAGATCCATGGCGATGTTGTGAATCATCAATTGGCGGCGGCCCATGGAGGCCAGctgccaccaccgccgccccCCCCGCAGGCCACTAGTCATGCGGCCAGTGCGGCAGCAGCGGCCGCAGCGGCATCTACAAATAATGCCGCTGTGGCGGCAGTGATGGCCTCCGCCAatgcggcggcggcagcagcagcggctgcaTCGGCAGCGGGCGGCGGTGGAGGATTACCGCCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTAACGACGACCAGCAGCTCGACGGCCAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGGcaatggcggcggcggcaacggCGGGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCAATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAACCGTTCATGTGCCAGGTGTGTGGCCAGGGCTTCACAACGTCACAGGATTTGACCCGCCACGGCAAGATTCACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTTTTCGCGAATAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTGAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCACACCAGTGTGATGTCTGCGGCAAGAAATATACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCACACAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGCTTAATCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCATCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCATACGGGCGACTCGCCCCACAAGTGCGAGTACTGCCAGAAGACGTTCACGCGGAAGGAGCATCTCAACAACCATATGCGTCAGCATTCAAGCGACAATCCGCATTGCTGCAATGTCTGCAATAAGCCGTTCACGCGCAAGGAGCACCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGGCCCTTCACCTGCGAGACATGCGGCAAATCGTTCCCCCTCAAGGGTAACCTGCTCTTCCATCAGCGCAGCCACACCAAGGGTCAGGAGATGGAGAGGCCCTTTGCCTGCGAGAAGTGTCCCAAGAATTTCATCTGCAAAGGTCACTTGGTCTCGCATATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAGATAACCGCTGGTGCGGCGGGCGGTGCCGGTGCCGTGCAGCTAACGCCGGGCCTGGTGCCCCTGGTCACCTCAACGCTCATCTCGCACAATGCCGCCGCCCAACAGCAGTCGCAAAAGCAACAGGCAGCCGCCGCTGCAGCGGCACAGCAACAggccgccgcagcagcagcggctcaGCAGCAGGCTGCCCAGCAACAGGCGGCAGCTGCACatcagcagcaccagcagcaagTGGCGGcacaacatcagcaacaggCTGCAGTGGCTgcccatcagcagcagcaacaacagttgcagcagcaacagcaattgCTGCAGTTGTCCATCCAACAGGCTGCTCACCATcatcagcaggagcagcatcgtcaacagcagcagcagcaacatcagcaacagcagcagcaacaacaacaacagcagcaacaacactCAGCAGCACAGCATCCGGGCCAGGCGCCGCCTCCGCAACAACAGCCGCCACCAGGAGTGCCCATCGCCTTGATAAGTGATCCCAGTGCTTTGGCCCGCGCCGCCATGCAGCTGCAGCATCTGCCAGCGAACGTGGAGCAACATCCGGTTGTTTACTAA
- Protein Sequence
- MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQQVTVTTTSSSTASSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLVTSTLISHNAAAQQQSQKQQAAAAAAAQQQAAAAAAAQQQAAQQQAAAAHQQHQQQVAAQHQQQAAVAAHQQQQQQLQQQQQLLQLSIQQAAHHHQQEQHRQQQQQQHQQQQQQQQQQQQQHSAAQHPGQAPPPQQQPPPGVPIALISDPSALARAAMQLQHLPANVEQHPVVY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00505532;
- 90% Identity
- iTF_00507738;
- 80% Identity
- -