Dosh005182.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila oshimai
Gene Symbol
-
Assembly
GCA_018150695.1
Location
JAECWM010000037.1:1061636-1068311[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.7e-05 0.0013 19.1 2.1 1 23 229 251 229 251 0.97
2 18 5.6e-06 0.00042 20.6 0.4 1 23 257 279 257 279 0.97
3 18 0.00083 0.061 13.8 0.9 1 23 285 307 285 307 0.95
4 18 1.2e-05 0.00088 19.6 3.1 1 23 313 335 313 335 0.97
5 18 2.7e-05 0.002 18.4 4.7 1 23 341 363 341 363 0.99
6 18 5e-05 0.0037 17.6 5.7 1 23 369 391 369 391 0.97
7 18 2.4e-07 1.8e-05 24.9 4.3 1 23 397 419 397 419 0.98
8 18 8.7e-08 6.4e-06 26.3 2.4 1 23 425 447 425 447 0.97
9 18 5.1e-05 0.0038 17.6 6.7 1 23 454 476 454 476 0.97
10 18 8.8e-05 0.0065 16.8 6.5 1 23 482 504 482 504 0.98
11 18 7.9e-06 0.00058 20.1 4.5 1 23 510 532 510 532 0.98
12 18 5.7e-06 0.00042 20.6 8.1 1 23 538 560 538 560 0.98
13 18 4.6e-06 0.00034 20.9 7.6 1 23 566 588 566 588 0.97
14 18 5.2e-07 3.9e-05 23.8 7.7 1 23 594 616 594 616 0.98
15 18 0.00016 0.012 16.0 9.5 1 23 622 645 622 645 0.95
16 18 5.8e-05 0.0043 17.4 0.9 1 23 651 673 651 673 0.98
17 18 0.00063 0.047 14.1 3.4 1 23 683 705 683 705 0.97
18 18 7.2e-06 0.00053 20.3 1.6 1 23 711 734 711 734 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCTAGCTCGGTGCCATCAGTTGTAGCCCCTGTTGTGACCACTGGTGGAACGACGATCACCTTGGGCGGTCCACCACATTTACCCAAATCGGAGCACAAAGAGGATGGCAAGCCGCCGCACGGCATCGAAATGTACAAGGTGAACATTGAGGATATCTCCCAGCTCTTCACCTACCACGAGGTTTTTGGCAAGATCCACGGCGATGTGGTCAATCATCAACTAGCAGCGGCTCATGGAGGTCAGTTGCCACCACCACCGCCCCTGCCTCCGTCGCAGGTTACCACCAGTCATGCGGCGAGTGCAGCGGCCGCAGCAGCAGCTGCATCCACCAATAATGCTGCGGTGGCAGCGGTAATGGCCTCTGCGAATGCAGCGGCGGCAGCAGCAGCGGCTGCTTCAGCGGCGGGGGGAGGAGTCGGTCTTCCGCCCGCAACCAGTGGCAATGGGGGCCAGCAGGTGACGGTGACGACAACCAGCAGCTCGACAAGCAGCGGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATACATGGCGTGGACGGCAATGGAGGCGGCAATGGAGGAGGCGGCGGCGGGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCCATTGCAACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTTCAGTTCCGGTACCAGCTAATCGTCCATAGGCGATACCACAGCGAACGGAAGCCGTTCATGTGCCAGGTGTGCGGCCAGGGGTTCACCACGTCGCAGGACTTGACACGTCATGGAAAGATCCACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCAAACAATACGAGCCTGGAGCGGCACATGAAACGTCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGGTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTCACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGTGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCACTTGCTTAACCACGTGCGCCAGCACACGGGAGAGTCGCCTCACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACGTACTGCACCAAGACGTTTACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACCTTTACACGCAAGGAGCACCTGACGAACCATGTGCGCCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTCACACGGAAGGAGCACCTCAACAACCACATGCGCCAGCACTCGAGCGACAATCCGCACTGCTGCAACGTCTGCAACAAGCCGTTCACGCGCAAGGAGCACCTGATCAATCACATGTCGCGATGCCACACCGGCGACCGGCCCTTCACCTGCGAGACCTGCGGCAAGTCGTTCCCGCTCAAGGGCAACCTGCTCTTCCACCAGCGCAGCCACACCAAGGGCCAGGAGATGGAGCGTCCCTTTGCCTGTGAGAAGTGCCCTAAGAACTTCATTTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCTGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACTACGATGCACACGATCCAGCAGATCACCGCGGGAGCAGCAGGCGGAGCAGGTGCGGTGCAACTGACTCCTGGACTGGTGCCCCTGCTGCAGCATCTGCCGGCGAACGTGGAGCAGCACCCGGTTGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPHLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPSQVTTSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGVGLPPATSGNGGQQVTVTTTSSSTSSGGGSTTSGGTTTTAGELLMPKMEGGIHGVDGNGGGNGGGGGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00505532;
90% Identity
iTF_00507738;
80% Identity
-