Basic Information

Insect: Drosophila kikkawai
Gene Symbol: -
Assembly: GCA_018152535.1
Location: NW:21115877-21133988[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.2e-05 0.0013 18.8 2.1 1 23 223 245 223 245 0.97

2 18 7.1e-06 0.00042 20.3 0.4 1 23 251 273 251 273 0.97

3 18 0.001 0.062 13.5 0.9 1 23 279 301 279 301 0.95

4 18 1.5e-05 0.00089 19.3 3.1 1 23 307 329 307 329 0.97

5 18 3.4e-05 0.002 18.2 4.7 1 23 335 357 335 357 0.99

6 18 6.2e-05 0.0037 17.3 5.7 1 23 363 385 363 385 0.97

7 18 3.1e-07 1.8e-05 24.6 4.3 1 23 391 413 391 413 0.98

8 18 1.1e-07 6.5e-06 26.0 2.4 1 23 419 441 419 441 0.97

9 18 6.4e-05 0.0038 17.3 6.7 1 23 447 469 447 469 0.97

10 18 0.00011 0.0066 16.6 6.5 1 23 475 497 475 497 0.98

11 18 9.9e-06 0.00059 19.9 4.5 1 23 503 525 503 525 0.98

12 18 7.2e-06 0.00043 20.3 8.1 1 23 531 553 531 553 0.98

13 18 5.8e-06 0.00035 20.6 7.6 1 23 559 581 559 581 0.97

14 18 6.5e-07 3.9e-05 23.6 7.7 1 23 587 609 587 609 0.98

15 18 0.0002 0.012 15.7 9.5 1 23 615 638 615 638 0.95

16 18 7.3e-05 0.0043 17.1 0.9 1 23 644 666 644 666 0.98

17 18 0.00079 0.047 13.9 3.4 1 23 676 698 676 698 0.97

18 18 9e-06 0.00054 20.0 1.6 1 23 704 727 704 727 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.2e-05	0.0013	18.8	2.1	1	23	223	245	223	245	0.97
2	18	7.1e-06	0.00042	20.3	0.4	1	23	251	273	251	273	0.97
3	18	0.001	0.062	13.5	0.9	1	23	279	301	279	301	0.95
4	18	1.5e-05	0.00089	19.3	3.1	1	23	307	329	307	329	0.97
5	18	3.4e-05	0.002	18.2	4.7	1	23	335	357	335	357	0.99
6	18	6.2e-05	0.0037	17.3	5.7	1	23	363	385	363	385	0.97
7	18	3.1e-07	1.8e-05	24.6	4.3	1	23	391	413	391	413	0.98
8	18	1.1e-07	6.5e-06	26.0	2.4	1	23	419	441	419	441	0.97
9	18	6.4e-05	0.0038	17.3	6.7	1	23	447	469	447	469	0.97
10	18	0.00011	0.0066	16.6	6.5	1	23	475	497	475	497	0.98
11	18	9.9e-06	0.00059	19.9	4.5	1	23	503	525	503	525	0.98
12	18	7.2e-06	0.00043	20.3	8.1	1	23	531	553	531	553	0.98
13	18	5.8e-06	0.00035	20.6	7.6	1	23	559	581	559	581	0.97
14	18	6.5e-07	3.9e-05	23.6	7.7	1	23	587	609	587	609	0.98
15	18	0.0002	0.012	15.7	9.5	1	23	615	638	615	638	0.95
16	18	7.3e-05	0.0043	17.1	0.9	1	23	644	666	644	666	0.98
17	18	0.00079	0.047	13.9	3.4	1	23	676	698	676	698	0.97
18	18	9e-06	0.00054	20.0	1.6	1	23	704	727	704	727	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCAGTTGTAGCCCCCGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGCCCACCACCGCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATCGAGATGTACAAGGTGAACATCGAGGACATATCTCAGCTCTTCACCTATCACGAGGTCTTTGGCAAGATCCATGGCGATGTTGTGAATCATCAATTGGCGGCGGCACATGGAGGCCAGCTtccaccaccgccgccccTTCCACCGCAGGCCACTAGTCATGCGGCCAgtgcggcagcagcagccgcagcagcgtCCACAAATAATGCCGCTGTGGCGGCAGTGATGGCCTCCGCCaatgcggcggcggcggcagcagcggctgcaTCCGCAGCGGGCGGAGGTCTGCCGCCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTAACGACGACCAGCAGCTCGACGGCCAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGGCAATGGCGGCGGCAACGGCGGGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCAATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGTGAACGGAAACCGTTCATGTGCCAGGTGTGTGGCCAGGGCTTCACCACGTCGCAGGATTTGACGCGCCACGGCAAGATTCACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCGAACAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGTGATGTCTGCGGCAAGAAATATACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAACCACATACTCTGGCACACAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCAAAGACGTTTACGCGCAAGGAGCATTTGCTTAACCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCATACGGGCGACTCGCCCCACAAGTGCGAGTACTGCCAGAAGACGTTTACGCGGAAGGAGCATCTCAACAACCATATGCGCCAGCATTCAAGCGACAATCCGCACTGCTGCAATGTCTGCAATAAGCCGTTCACGCGCAAGGAGCACCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGGCCCTTCACCTGCGAGACATGCGGCAAATCGTTTCCGCTCAAGGGCAACCTGCTCTTCCATCAACGTAGCCACACCAAGGGCCAAGAGATGGAGAGACCATTTGCCTGCGAGAAGTGCCCCAAGAATTTCATCTGTAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCcgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAGATAACCGCTGGTGCGGCGGGCGGTGCCGGTGCCGTGCAGCTAACACCGGGTCTGGTGCCGCTGGTCACCTCAACGCTTATCTCGCACAATGCCGCCGCCCAGCAGCAGTCGCAGAAGCAACAGGCAGCCGCCGCTGCAGCGGCCCAGCAACAGgctgccgcagcagcagcggctcaGCAGCAGGCTGCCCAGCAACAGGCGGCGGCCGCCcatcagcagcaccagcagcaagTGGCGGCACAGCATCAGCAACAGGCGGCAGTGGCTGcccatcagcagcaacaacagcagctgcagcagcagcagcaattgctGCAGTTGTCCATCCAACAGGCGGCTCATCACcatcagcaggagcagcaccgtcaacagcagcagcagcagcaacaccagcaacagcagcagcaacaacagcagcagcagcaacagcaccatcagcagcaacagcatccaGGCCaagcgccgccgccgcagcaacAGCCGCCACCTGGAGTGCCCATCGCCTTGATAAGTGATCCCAGTGCTTTGGCCCGCGCCGCCATGCAGCTGCAGCATCTGCCAGCGAACGTGGAGCAACACCCGGTTGTTTACTAA
Protein Sequence: MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGLPPATSGNGGQQVTVTTTSSSTASSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLVTSTLISHNAAAQQQSQKQQAAAAAAAQQQAAAAAAAQQQAAQQQAAAAHQQHQQQVAAQHQQQAAVAAHQQQQQQLQQQQQLLQLSIQQAAHHHQQEQHRQQQQQQQHQQQQQQQQQQQQQHHQQQQHPGQAPPPQQQPPPGVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505532;
90% Identity: iTF_00507738;
80% Identity: -