Dmay007839.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mayri
Gene Symbol
-
Assembly
GCA_008042485.1
Location
VNJN01009644.1:126013-132469[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.7e-05 0.0012 19.1 2.1 1 23 225 247 225 247 0.97
2 18 5.4e-06 0.00038 20.6 0.4 1 23 253 275 253 275 0.97
3 18 0.0008 0.056 13.8 0.9 1 23 281 303 281 303 0.95
4 18 1.2e-05 0.0008 19.6 3.1 1 23 309 331 309 331 0.97
5 18 2.6e-05 0.0018 18.4 4.7 1 23 337 359 337 359 0.99
6 18 4.8e-05 0.0033 17.6 5.7 1 23 365 387 365 387 0.97
7 18 2.3e-07 1.6e-05 24.9 4.3 1 23 393 415 393 415 0.98
8 18 8.4e-08 5.9e-06 26.3 2.4 1 23 421 443 421 443 0.97
9 18 4.9e-05 0.0034 17.6 6.7 1 23 450 472 450 472 0.97
10 18 8.5e-05 0.006 16.8 6.5 1 23 478 500 478 500 0.98
11 18 7.6e-06 0.00053 20.1 4.5 1 23 506 528 506 528 0.98
12 18 5.5e-06 0.00039 20.6 8.1 1 23 534 556 534 556 0.98
13 18 4.5e-06 0.00031 20.9 7.6 1 23 562 584 562 584 0.97
14 18 5e-07 3.5e-05 23.9 7.7 1 23 590 612 590 612 0.98
15 18 0.00016 0.011 16.0 9.5 1 23 618 641 618 641 0.95
16 18 5.6e-05 0.0039 17.4 0.9 1 23 647 669 647 669 0.98
17 18 0.00061 0.043 14.1 3.4 1 23 679 701 679 701 0.97
18 18 6.9e-06 0.00048 20.3 1.6 1 23 707 730 707 730 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCAGTTGTATCCCCCGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGACCACCACCGCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATTGAGATGTACAAGGTTAACATCGAGGACATCTCCCAGCTCTTCACCTATCACGAGGTCTTTGGCAAGATCCATGGCGATGTTGTGAATCATCAATTGGCAGCGGCCCATGGAGGCCAGctgccaccaccgccgccccTTCCACCGCAGGCCACTAGTCATGCGGCCagtgcggcagcagcagccgcagcagcgtCCACAAATAATGCCGCTGTAGCGGCAGTAATGGCCTCCGCCaatgcggcggcggcggcagcggcggctgcaTCAGCAGcgggcggcggtggaggactGCCGCCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTAACGACGACCAGCAGCTCGACGGCCAGCAGCGTCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGGCAATGGCGGCGGCAACGGCGGGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCAATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTATCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAACCGTTCATGTGCCAGGTGTGTGGCCAGGGCTTCACCACGTCGCAGGATTTGACCCGCCACGGCAAGATTCACATTGGCGGGCCCATGTTTACCTGCATCGTGTGCTTCAATGTGTTCGCGAATAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGATAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTGAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGTGATGTCTGCGGCAAGAAATATACGCGCAAGGAGCACCTAGCTAACCATATGCGCTCCCACACAAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCACACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGCTTAACCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTTACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCATCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCATACGGGCGACTCGCCCCACAAGTGCGAGTACTGCCAGAAGACGTTTACGCGGAAGGAGCATCTCAACAACCATATGCGTCAGCATTCAAGCGACAATCCGCACTGCTGCAATGTCTGCAATAAGCCGTTCACGCGCAAGGAGCACCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGACCCTTCACCTGCGAGACATGCGGCAAATCGTTCCCCCTCAAGGGTAACCTGCTCTTCCATCAGCGTAGCCATACCAAGGGCCAGGAGATGGAGCGGCCATTTGCCTGCGAGAAGTGCCCCAAGAATTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCATTCGGCGACCACCACGATGCACACTATCCAGCAGATAACAGCTGGTGCGGCGGGCGGTGCCAGTGCCGTGCAGCTAACACCGGGCCTGGTGCCCCTGCTGCAGCATCTGCCAGCGAACGTGGAGCAACACCCGGTTGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVSPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQQVTVTTTSSSTASSVGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGASAVQLTPGLVPLLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00505532;
90% Identity
iTF_00507738;
80% Identity
-