Dtru002690.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila truncata
Gene Symbol
-
Assembly
GCA_008042515.1
Location
VNJQ01003742.1:24270-30775[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.11 9.6 7.0 1.3 7 23 210 226 210 226 0.95
2 13 2.2e-07 1.9e-05 24.9 4.3 1 23 232 254 232 254 0.98
3 13 7.9e-08 6.9e-06 26.3 2.4 1 23 260 282 260 282 0.97
4 13 4.6e-05 0.004 17.6 6.7 1 23 289 311 289 311 0.97
5 13 8e-05 0.007 16.8 6.5 1 23 317 339 317 339 0.98
6 13 7.2e-06 0.00062 20.1 4.5 1 23 345 367 345 367 0.98
7 13 5.2e-06 0.00045 20.6 8.1 1 23 373 395 373 395 0.98
8 13 4.2e-06 0.00037 20.9 7.6 1 23 401 423 401 423 0.97
9 13 4.7e-07 4.1e-05 23.8 7.7 1 23 429 451 429 451 0.98
10 13 0.00015 0.013 16.0 9.5 1 23 457 480 457 480 0.95
11 13 5.2e-05 0.0046 17.4 0.9 1 23 486 508 486 508 0.98
12 13 0.00057 0.05 14.1 3.4 1 23 518 540 518 540 0.97
13 13 6.5e-06 0.00057 20.3 1.6 1 23 546 569 546 569 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCAGTTGTAGCCCCCGTTGTGACCACTGGTGGGACGACGATCACCTTGGGCGGACCACCACCGCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATTGAGATGTACAAGGTGAACATCGAGGACATCTCTCAGCTCTTTACCTATCACGAGGTCTTTGGCAAGATCCATGGCGATGTTGTGAATCATCAATTGGCGGCGGCCCATGGAGGCCAGttgccaccaccgccgcccctTCCACCGCAGGCCACTAGTCATGCGGCCAGTgcggcagcagccgcagcagcggcGTCTACAAATAATGCCGCTGTGGCGGCAGTTATGGCCTCCGCCaatgcggcggcggcagcagcagcggctgcatCAGCAGCGGGCGGCGGTGGAGGACTACCGCCGGCCACCAGCGGTAATGGGGGCCAGCAGGTGACTGTAACGACGACCAGCAGCTCGACGGCCAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCGGCAAtggcggcggcaacggcggGCAGAACAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGTGATGTCTGCGGCAAGAAATATACGCGCAAGGAGCACCTAGCCAACCATATGCGATCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCACACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGCTTAACCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCATCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCATACGGGCGACTCGCCCCACAAGTGCGAGTACTGCCAGAAGACGTTCACGCGGAAGGAGCATCTCAACAACCATATGCGTCAGCATTCGAGCGACAATCCGCACTGCTGCAATGTCTGCAACAAGCCGTTCACGCGCAAGGAGCACCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGGCCCTTCACCTGCGAGACATGCGGCAAATCCTTCCCGCTCAAGGGTAACCTGCTCTTCCATCAGCGTAGCCACACCAAGGGCCAGGAGATGGAGCGGCCCTTTGCCTGTGAGAAGTGCCCCAAGAATTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCAGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAGATAACCGGTGGTGCGGCGGGCGGTGCCGGTGCCGTGCAGCTAACGCCGGGCCTGGTGCCCCTGGTCACCTCAACGCTCATCTCGCACAATGccgccgcccagcagcaaTCGCAGAAGCAACAGGCAGCCGCCGTCGCAGCGGCCCAGCAACAGGCTgccgcggcagcagcggctcaACAGCAGGCTGCCCAGCAACAGGCGGCTGCTGCCCatcagcaacaccagcagcaagtggcggcacagcatcagcaacaggcTGCAGTGGCTGcccatcagcagcaacaacaacagcagttgcagcaacagcaacaattgctGCAGTTGTCCATCCAGCAGGCGGCTCACCAtcatcagcaggagcagcatcgtcaacaacagcagcagcaacaccagcagcagcagcagcaacaacaacagcaacagcagcagcaacaccatcagcagcagcagcatccaggCCAAGCGCCGCCGCCGCAACAACAGCCGCCACCAGGAGTGCCCATCGCCTTGATAAGTGATCCCAGTGCTTTGGCCCGCGCCGCcatgcagctgcagcatctGCCAGCGAACGTGGAGCAACATCCGGTTGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQQVTVTTTSSSTASSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGNGGQNKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITGGAAGGAGAVQLTPGLVPLVTSTLISHNAAAQQQSQKQQAAAVAAAQQQAAAAAAAQQQAAQQQAAAAHQQHQQQVAAQHQQQAAVAAHQQQQQQQLQQQQQLLQLSIQQAAHHHQQEQHRQQQQQQHQQQQQQQQQQQQQQHHQQQQHPGQAPPPQQQPPPGVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00505532;
90% Identity
iTF_00483107;
80% Identity
-